Here are 20 NCERT-based NEET-level MCQs on the topic Transport of CO₂ along with
answers:
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MCQs: Transport of CO₂ (with Answers)
1. What percentage of CO₂ is transported in the form of bicarbonate ions in the blood?
a) 23%
b) 7%
c) 20%
d) 70%
Ans: d) 70%
2. CO₂ binds with the globin part of haemoglobin to form:
a) Carboxyhaemoglobin
b) Carbamino-haemoglobin
c) Carbonic acid
d) Oxyhaemoglobin
Ans: b) Carbamino-haemoglobin
3. Which enzyme catalyzes the formation of carbonic acid from CO₂ and water in RBCs?
a) Amylase
b) Pepsin
c) Carbonic anhydrase
d) Trypsin
Ans: c) Carbonic anhydrase
4. How is CO₂ mainly transported in the blood?
a) Dissolved in plasma
b) As carbamino-haemoglobin
c) As bicarbonate ions
d) Bound to plasma proteins
Ans: c) As bicarbonate ions
5. What is the role of carbonic anhydrase in CO₂ transport?
a) Converts bicarbonate into CO₂
b) Converts CO₂ into carbonic acid
c) Converts oxygen into water
d) Breaks down haemoglobin
Ans: b) Converts CO₂ into carbonic acid
6. The reaction CO₂ + H₂O ⇌ H₂CO₃ ⇌ H⁺ + HCO₃⁻ occurs rapidly due to:
a) High pO₂
b) Presence of haemoglobin
c) Presence of carbonic anhydrase
d) Low pCO₂
Ans: c) Presence of carbonic anhydrase
7. The chloride shift is important for:
a) O₂ binding
b) Ionic balance during CO₂ transport
c) Active transport of CO₂
d) Enzyme activity
Ans: b) Ionic balance during CO₂ transport
8. Where does the majority of conversion of CO₂ into bicarbonate occur?
a) Plasma
b) RBCs
c) Lungs
d) Alveolar fluid
Ans: b) RBCs
9. In tissues, CO₂ diffuses into blood and is transported primarily as:
a) Oxyhaemoglobin
b) Bicarbonate ions
c) Carboxyhaemoglobin
d) Free CO₂ gas
Ans: b) Bicarbonate ions
10. The Haldane effect refers to:
a) Binding of oxygen to haemoglobin
b) Effect of CO₂ on O₂ affinity
c) Increased CO₂ binding when O₂ is released
d) Bohr shift in haemoglobin
Ans: c) Increased CO₂ binding when O₂ is released
11. What facilitates the release of oxygen from oxyhaemoglobin at the tissue level?
a) Low pCO₂
b) High pCO₂
c) High pO₂
d) Low temperature
Ans: b) High pCO₂
12. What percentage of CO₂ is transported dissolved directly in plasma?
a) 7%
b) 20%
c) 23%
d) 70%
Ans: a) 7%
13. Formation of carbamino-haemoglobin takes place at:
a) Lungs
b) Alveoli
c) Tissues
d) Capillaries of lungs
Ans: c) Tissues
14. Which factor does not influence CO₂ transport in blood?
a) Partial pressure of oxygen
b) Enzyme carbonic anhydrase
c) Temperature
d) Vitamin D concentration
Ans: d) Vitamin D concentration
15. What is the main form in which CO₂ is transported from tissues to lungs?
a) Bound to haemoglobin
b) As dissolved gas
c) As carbonic acid
d) As bicarbonate ions
Ans: d) As bicarbonate ions
16. In lungs, the high partial pressure of oxygen leads to:
a) Formation of carbamino-haemoglobin
b) Increased CO₂ uptake
c) Dissociation of carbamino-haemoglobin
d) Conversion of O₂ into CO₂
Ans: c) Dissociation of carbamino-haemoglobin
17. How does the bicarbonate ion return to alveoli from the plasma?
a) Passive diffusion
b) Active transport
c) Reverse chloride shift
d) Pinocytosis
Ans: c) Reverse chloride shift
18. What promotes the formation of bicarbonate at tissue level?
a) High pO₂
b) Low temperature
c) High pCO₂
d) Low pCO₂
Ans: c) High pCO₂
19. The Bohr effect is primarily influenced by:
a) CO₂ concentration
b) Oxygen concentration
c) Temperature
d) Salts in plasma
Ans: a) CO₂ concentration
20. Which process is responsible for maintaining ionic balance during CO₂ transport?
a) Bohr shift
b) Chloride shift
c) Passive diffusion
d) Reverse osmosis
Ans: b) Chloride shift
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