Safety Data Sheet

acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier

Trade name Aflatoxin B1 in acetonitrile
Article number 10000340, 10003652
1.2 Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses Laboratory and analytical use
Uses advised against Do not use for products which come into contact
with foodstuffs. Do not use for private purposes
(household).

1.3 Details of the supplier of the safety data sheet

Romer Labs® Division Holding GmbH
Erber Campus 1
3131 Getzersdorf
Austria
Telephone: +43 2782 803 0
e-mail: [email protected]
Website: www.romerlabs.com
Manufacturer

Country Name Street Postal code/city Telephone e-Mail

Austria Romer Labs Divi- Technopark 5 3430 Tulln +43 2272 615 33 0 office-
sion Holding GmbH europe@romerlabs.
com

1.4 Emergency telephone number

Emergency information service +43 2782 803 0
This number is only available during the follow-
ing office hours: Mon - Thu 09:00 - 16:00, Fri 09:00
- 12:00, GMT+1

Poison centre

Country Name Telephone

Austria Vergiftungsinformationszentrale +43 1 406 43 43 (24h)

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification acc. to GHS

Section Hazard class Category Hazard class and cat- Hazard state-
egory ment

2.6 flammable liquid 2 Flam. Liq. 2 H225

3.1O acute toxicity (oral) 4 Acute Tox. 4 H302

3.1D acute toxicity (dermal) 4 Acute Tox. 4 H312

3.1I acute toxicity (inhal.) 4 Acute Tox. 4 H332

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

Section Hazard class Category Hazard class and cat- Hazard state-
egory ment

3.3 serious eye damage/eye irritation 2 Eye Irrit. 2 H319

For full text of abbreviations: see SECTION 16.

The most important adverse physicochemical, human health and environmental effects
The product is combustible and can be ignited by potential ignition sources.

2.2 Label elements

Labelling
- Signal word danger
- Pictograms
GHS02, GHS07

- Hazard statements
H225 Highly flammable liquid and vapour.
H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled.
H319 Causes serious eye irritation.

- Precautionary statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No
smoking.
P233 Keep container tightly closed.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P312 Call a POISON CENTRE/doctor if you feel unwell.
P370+P378 In case of fire: Use sand, carbon dioxide or powder extinguisher to extinguish.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to industrial combustion plant.

- Hazardous ingredients for labelling acetonitrile

2.3 Other hazards
Results of PBT and vPvB assessment
This mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients

3.1 Substances
Not relevant (mixture)

3.2 Mixtures
Description of the mixture

Name of substance Identifier Wt% Classification acc. to GHS Pictograms

acetonitrile CAS No ≥ 90 Flam. Liq. 2 / H225

75-05-8 Acute Tox. 4 / H302
Acute Tox. 4 / H312
Acute Tox. 4 / H332
Eye Irrit. 2 / H319

For full text of abbreviations: see SECTION 16.

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

SECTION 4: First aid measures

4.1 Description of first aid measures

General notes
Do not leave affected person unattended. Remove victim out of the danger area. Keep affected person warm, still and
covered. Take off immediately all contaminated clothing. In all cases of doubt, or when symptoms persist, seek medic-
al advice. In case of unconsciousness place person in the recovery position. Never give anything by mouth.

Following inhalation
If breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. Provide fresh air.

Following skin contact

Wash with plenty of soap and water.

Following eye contact

Remove contact lenses, if present and easy to do. Continue rinsing. Irrigate copiously with clean, fresh water for at
least 10 minutes, holding the eyelids apart.

Following ingestion
Rinse mouth with water (only if the person is conscious). Do NOT induce vomiting.

4.2 Most important symptoms and effects, both acute and delayed
Symptoms and effects are not known to date.

4.3 Indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media
Water spray, BC-powder, Carbon dioxide (CO2)

Unsuitable extinguishing media

Water jet

5.2 Special hazards arising from the substance or mixture

In case of insufficient ventilation and/or in use, may form flammable/explosive vapour-air mixture. Solvent vapours are
heavier than air and may spread along floors. Places which are not ventilated, e.g. unventilated below ground level
areas such as trenches, conduits and shafts, are particularly prone to the presence of flammable substances or mix-
tures.

Hazardous combustion products

Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2)

5.3 Advice for firefighters

In case of fire and/or explosion do not breathe fumes. Co-ordinate firefighting measures to the fire surroundings. Do
not allow firefighting water to enter drains or water courses. Collect contaminated firefighting water separately. Fight
fire with normal precautions from a reasonable distance.

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

For non-emergency personnel
Remove persons to safety.

For emergency responders

Wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2 Environmental precautions

Keep away from drains, surface and ground water. Retain contaminated washing water and dispose of it.

6.3 Methods and material for containment and cleaning up

Advices on how to contain a spill
Covering of drains

Advices on how to clean up a spill

Wipe up with absorbent material (e.g. cloth, fleece). Collect spillage: sawdust, kieselgur (diatomite), sand, universal
binder

Appropriate containment techniques

Use of adsorbent materials.

Other information relating to spills and releases

Place in appropriate containers for disposal. Ventilate affected area.

6.4 Reference to other sections

Hazardous combustion products: see section 5. Personal protective equipment: see section 8. Incompatible materials:
see section 10. Disposal considerations: see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Recommendations
- Measures to prevent fire as well as aerosol and dust generation
Use local and general ventilation. Avoidance of ignition sources. Keep away from sources of ignition - No smoking.
Take precautionary measures against static discharge. Use only in well-ventilated areas. Due to danger of explosion,
prevent leakage of vapours into cellars, flues and ditches. Ground/bond container and receiving equipment. Use ex-
plosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools.

- Specific notes/details
Places which are not ventilated, e.g. unventilated below ground level areas such as trenches, conduits and shafts, are
particularly prone to the presence of flammable substances or mixtures. Vapours are heavier than air, spread along
floors and form explosive mixtures with air. Vapours may form explosive mixtures with air.

Advice on general occupational hygiene

Wash hands after use. Do not eat, drink and smoke in work areas. Remove contaminated clothing and protective
equipment before entering eating areas. Never keep food or drink in the vicinity of chemicals. Never place chemicals
in containers that are normally used for food or drink. Keep away from food, drink and animal feedingstuffs.

7.2 Conditions for safe storage, including any incompatibilities

Managing of associated risks
- Explosive atmospheres
Keep container tightly closed and in a well-ventilated place. Use local and general ventilation. Keep cool. Protect from
sunlight.

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

- Flammability hazards
Keep away from sources of ignition - No smoking. Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking. Take precautionary measures against static discharge. Protect from sunlight.

- Ventilation requirements
Keep any substance that emits harmful vapours or gases in a place that allows these to be permanently extracted. Use
local and general ventilation. Ground/bond container and receiving equipment.

- Packaging compatibilities
Only packagings which are approved (e.g. acc. to the Dangerous Goods Regulations) may be used.

7.3 Specific end use(s)

See section 16 for a general overview.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational exposure limit values (Workplace Exposure Limits)

Coun- Name of agent CAS No Identi- TWA TWA STEL STEL Ceiling-C Ceiling-C Nota- Source
try fier [ppm] [mg/m³] [ppm] [mg/m³] [ppm] [mg/m³] tion

EU acetonitrile 75-05-8 IOELV 40 70 2006/

15/EC
Notation
Ceiling-C ceiling value is a limit value above which exposure should not occur
STEL short-term exposure limit: a limit value above which exposure should not occur and which is related to a 15-minute peri-
od (unless otherwise specified)
TWA time-weighted average (long-term exposure limit): measured or calculated in relation to a reference period of 8 hours
time-weighted average (unless otherwise specified)

8.2 Exposure controls

Appropriate engineering controls
General ventilation.

Individual protection measures (personal protective equipment)

Eye/face protection
Wear eye/face protection.

Skin protection
- Hand protection
Chemical protection gloves are suitable, which are tested according to EN 374. Wear protective gloves. Check leak-
tightness/impermeability prior to use. For special purposes, it is recommended to check the resistance to chemicals of
the protective gloves mentioned above together with the supplier of these gloves.

- Other protection measures

Take recovery periods for skin regeneration. Wash hands thoroughly after handling.

Environmental exposure controls

Use appropriate container to avoid environmental contamination. Keep away from drains, surface and ground water.

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

Appearance

Physical state liquid

Colour colourless

Odour characteristic

Other safety parameters

pH (value) not determined

Melting point/freezing point -46 °C

Initial boiling point and boiling range 81 °C

Flash point 5 °C

Evaporation rate not determined

Flammability (solid, gas) not relevant, (fluid)

Explosive limits

- Lower explosion limit (LEL) 4.4 vol%

- Upper explosion limit (UEL) 16 vol%

Vapour pressure 97 hPa at 20 °C

Density not determined

Vapour density this information is not available

Relative density information on this property is not available

Solubility(ies) not determined

Partition coefficient

- n-octanol/water (log KOW) this information is not available

Auto-ignition temperature 525 °C

Viscosity not determined

Explosive properties none

Oxidising properties none

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

9.2 Other information there is no additional information

SECTION 10: Stability and reactivity

10.1 Reactivity
Concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials". The mixture contains react-
ive substance(s). Risk of ignition.

If heated:
Risk of ignition

10.2 Chemical stability

See below "Conditions to avoid".

10.3 Possibility of hazardous reactions

No known hazardous reactions.

10.4 Conditions to avoid

Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

Hints to prevent fire or explosion

Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools. Take precautionary meas-
ures against static discharge.

10.5 Incompatible materials

Oxidisers

10.6 Hazardous decomposition products

Reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are
not known. Hazardous combustion products: see section 5.

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Test data are not available for the complete mixture.

Classification procedure
The method for classification of the mixture is based on ingredients of the mixture (additivity formula).

Classification acc. to GHS

Acute toxicity
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

- Acute toxicity estimate (ATE)

Oral 500.1 mg/kg
Dermal 1,250 mg/kg
Inhalation: vapour 11 mg/l/4h

Acute toxicity estimate (ATE) of components of the mixture

Name of substance CAS No Exposure route ATE

acetonitrile 75-05-8 oral 500 mg/kg

acetonitrile 75-05-8 dermal 1,250 mg/kg

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

Acute toxicity estimate (ATE) of components of the mixture

Name of substance CAS No Exposure route ATE

acetonitrile 75-05-8 inhalation: vapour 11 mg/l/4h

Skin corrosion/irritation
Shall not be classified as corrosive/irritant to skin.

Serious eye damage/eye irritation

Causes serious eye irritation.

Respiratory or skin sensitisation

Shall not be classified as a respiratory or skin sensitiser.

Germ cell mutagenicity

Shall not be classified as germ cell mutagenic.

Carcinogenicity
Shall not be classified as carcinogenic.

Reproductive toxicity
Shall not be classified as a reproductive toxicant.

Specific target organ toxicity - single exposure

Shall not be classified as a specific target organ toxicant (single exposure).

Specific target organ toxicity - repeated exposure

Shall not be classified as a specific target organ toxicant (repeated exposure).

Aspiration hazard
Shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information

12.1 Toxicity
Shall not be classified as hazardous to the aquatic environment.

12.2 Persistence and degradability

Data are not available.

12.3 Bioaccumulative potential

Data are not available.

12.4 Mobility in soil

Data are not available.

12.5 Results of PBT and vPvB assessment

Data are not available.

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

12.6 Other adverse effects

Endocrine disrupting potential
None of the ingredients are listed.

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Waste treatment-relevant information
Solvent reclamation/regeneration.

Sewage disposal-relevant information

Do not empty into drains. Avoid release to the environment. Refer to special instructions/safety data sheets.

Waste treatment of containers/packagings

Only packagings which are approved (e.g. acc. to the Dangerous Goods Regulations) may be used. Completely emp-
tied packages can be recycled. Handle contaminated packages in the same way as the substance itself.

Relevant provisions relating to waste (Basel Convention)

Properties of waste which render it hazardous
H3 Flammable liquids

Remarks
Please consider the relevant national or regional provisions. Waste shall be separated into the categories that can be
handled separately by the local or national waste management facilities.

SECTION 14: Transport information

14.1 UN number 1648

14.2 UN proper shipping name ACETONITRILE
14.3 Transport hazard class(es)
Class 3 (flammable liquids)
14.4 Packing group II (substance presenting medium danger)
14.5 Environmental hazards non-environmentally hazardous acc. to the dan-
gerous goods regulations
14.6 Special precautions for user
There is no additional information.

14.7 Transport in bulk according to Annex II of MARPOL and the IBC Code
The cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulations

Transport information - National regulations - Additional information (UN RTDG)
UN number 1648
Proper shipping name ACETONITRILE
Class 3
Packing group II
Danger label(s) 3

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

Special provisions (SP) - (UN RTDG)

Excepted quantities (EQ) E2 (UN RTDG)
Limited quantities (LQ) 1 l (UN RTDG)
International Maritime Dangerous Goods Code (IMDG)
UN number 1648
Proper shipping name ACETONITRILE
Class 3
Marine pollutant -
Packing group II
Danger label(s) 3

Excepted quantities (EQ) E2

Limited quantities (LQ) 1L
EmS F-E, S-D
Stowage category B
International Civil Aviation Organization (ICAO-IATA/DGR)
UN number 1648
Proper shipping name Acetonitrile
Class 3
Packing group II
Danger label(s) 3

Excepted quantities (EQ) E2

Limited quantities (LQ) 1L

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
There is no additional information.

National inventories

Country Inventory Status

EU REACH Reg. not all ingredients are listed

US TSCA not all ingredients are listed

Legend
REACH Reg. REACH registered substances
TSCA Toxic Substance Control Act

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

15.2 Chemical Safety Assessment

Chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other information

Abbreviations and acronyms

Abbr. Descriptions of used abbreviations

2006/15/EC Commission Directive establishing a second list of indicative occupational exposure limit values in imple-
mentation of Council Directive 98/24/EC and amending Directives 91/322/EEC and 2000/39/EC
Acute Tox. Acute toxicity

ATE Acute Toxicity Estimate

CAS Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

Ceiling-C Ceiling value

DGR Dangerous Goods Regulations (see IATA/DGR)

EmS Emergency Schedule

Eye Dam. Seriously damaging to the eye

Eye Irrit. Irritant to the eye

Flam. Liq. Flammable liquid

GHS "Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Na-
tions
IATA International Air Transport Association

IATA/DGR Dangerous Goods Regulations (DGR) for the air transport (IATA)
ICAO International Civil Aviation Organization

IMDG International Maritime Dangerous Goods Code

IOELV Indicative occupational exposure limit value

MARPOL International Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")
PBT Persistent, Bioaccumulative and Toxic

ppm Parts per million

REACH Registration, Evaluation, Authorisation and Restriction of Chemicals

STEL Short-term exposure limit

TWA Time-weighted average

vPvB Very Persistent and very Bioaccumulative

Key literature references and sources for data

UN Recommendations on the Transport of Dangerous Good. International Maritime Dangerous Goods Code (IMDG).
Dangerous Goods Regulations (DGR) for the air transport (IATA).

Classification procedure
Physical and chemical properties: The classification is based on tested mixture.
Health hazards, Environmental hazards: The method for classification of the mixture is based on ingredients of the mix-
ture (additivity formula).

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 Safety Data Sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

Aflatoxin B1 in acetonitrile
version number GHS 1.0 Date of compilation: 29.04.2019
replaces version of

List of relevant phrases (code and full text as stated in chapter 2 and 3)

Code Text

H225 Highly flammable liquid and vapour.

H302 Harmful if swallowed.

H312 Harmful in contact with skin.

H319 Causes serious eye irritation.

H332 Harmful if inhaled.

Disclaimer
This information is based upon the present state of our knowledge. This SDS has been compiled and is solely intended
for this product.
copyright: Romer Labs

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