BOC 2: Chemistry - Endocrinology and Tumor

Markers
Save

Practice questions for this set

Learn 1 /7 Study with Learn

vanillylmandelic acid (VMA)

VMA is a major metabolite of epinephrine and norepinephrine.

Choose matching term

220. A 68-year-old female patient tells her physician of being "cold all the time" and

recent weight gain, with no change in diet. The doctor orders a TSH level, and the
1
laboratory reports a value of 8.7 uU/mL (reference range = 0.5 - 5.0 uU/mL). This patient

most likely has:

2 231. Night blindness is associated with deficiency of which of the following vitamins?

237. The urinary excretion product measured as an indicator of epinephrine production

4 211. TSH is produced by the:

211. TSH is produced by pituitary gland

the:

212. A patient has the hypothyroidism

following thyroid profile:

total T4: decreased

free T4: decreased

thyroid peroxidase

antibody: positive

TSH: decreased

This patient most probably

has:

213. A 45-year-old woman primary hypothyroidism

complains of fatigue, heat

intolerance and hair loss.

Total and free T4 are

abnormally low. If the TSH

showed marked elevation,

this would be consistent

with:

214. The majority of triiodothyronine (T3)

thyroxine (T4) is converted

into the more biologically

active hormone:
215. A 2-year-old child thyroid stimulating hormone (TSH)

with a decreased serum T4

is described as being

somewhat dwarfed,

stocky, overweight, and

having coarse features. Of

the following, the most

informative addiotional

laboratory test would be

the serum:

217. The recommended thyroid stimulating hormone (TSH)

initial thyroid function test

for either a healthy,

asymptomatic patient or a

patient with symptoms

which may be related to a

thyroid disorder:

218. The screening test for total thyroxine (T4) level in the newborn

congenital hypothyroidism

is based upon:

219. Which one of the TSH increased, T4 decreased, positive for

following sets of results is antimicrosomal antibody

consistent with primary

hypothyroidism, (eg,

Hashimoto thyroiditis):
220. A 68-year-old female primary hypothyroidism

patient tells her physician

of being "cold all the time"

and recent weight gain,

with no change in diet. The

doctor orders a TSH level,

and the laboratory reports

a value of 8.7 uU/mL

(reference range = 0.5 -

5.0 uU/mL). This patient

most likely has:

221. Which of the following human chorionic gonadotropin (HCG)

is secreted by the

placenta and used for the

early detection of

pregnancy?

224. In amniotic fluid, the measurement of absorbance at 450 nm

procedure used to detect

hemolytic disease of the

newborn is:

225. During a normal 8 - 10

pregnancy, quantitative

HCG levels peak how

many weeks after the last

menstrual period?

227. Which of the aldosterone

following steroids is an

adrenal cortical hormone?

228. What common cholesterol

substrate is used in the

biosynthesis of adrenal

steroids, including

androgens and

estrogens?
230. Plasma for cortisol a normal finding

determinations were

collected at 7 AM, after

waking the patient, and at

10 PM that evening. The

cortisol level of the

morning sample was

higher than the evening

sample. This is consistent

with:

231. Night blindness is vitamin A

associated with deficiency

of which of the following

vitamins?

232. Beriberi is associated thiamine (B1)

with deficiency of vitamin:

233. Scurvy is associated vitamin C

with deficiency of which of

the following vitamins?

234. Rickets is associated vitamin D

with deficiency of which of

the following vitamins?

235. Pellagra is associated niacin

with deficiency of which of

the following vitamins?

236. The major action of increased vasoconstriction

angiotensin II is:

237. The urinary excretion vanillylmandelic acid (VMA)

product measured as an VMA is a major metabolite of epinephrine and

indicator of epinephrine norepinephrine.

production is:
238. Which of the parathyroid hormone

following hormones

regulates normal blood

calcium levels?

240. A diagnosis of impaired response to ACTH stimulation

primary adrenal ACTH is used to differentiate primary and secondary

insufficiency requires adrenal insufficiency.

demonstration of:

241. The screen for adrenal 24-hour urine free cortisol

cortical hyperfunction

with the greatest

sensitivity and specificity

is:

244. Which of the collect a 24-hour urine free cortisol

following sample

collections would give an

accurate assessment of

potential excess cortisol

production

(hypercortisolism)?

246. Aldosterone is angiotensin II

released by the adrenal

cortex upon stimulation

by:

248. Clinical assays for monitoring the course of a known cancer

tumor markers are most

important for:

249. Detection of which of alpha-fetoprotein

the following substances

is most useful to monitor

the course of a patient

with testicular cancer?

concentrations of alpha-

fetoprotein (AFP) in adults

are most characteristically

associated with:

251. Carcinoembryonic colon

antigen (CEA) is most

likely produced in a

malignancy involving the:

252. Which of the total prostate specific antigen (PSA)

following is useful in

detection and

management of carcinoma

of the prostate?

253. Which of the tumor markers are useful in tracking the efficacy of

following statements most treatment

correctly describes the

utility of clinical laboratory

assays for tumor markers?

254. Cancer antigen 125 ovarian and endometrial carcinoma

(CA 125) is a tumor marker

associated with:

255. In addition to benign prostatic hyperplasia

carcinoma of the prostate,

elevated prostate specific

antigen (PSA) can occur

due to: