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Bpharm 6 Sem Biopharmaceutics and Pharmacokinetics Bp604t Jun 2024

This document outlines the structure of the BPHARM (Semester VI) Theory Examination for Biopharmaceutics and Pharmacokinetics, scheduled for 2023-24. It includes three sections with various questions covering topics such as drug elimination, pharmacokinetic models, and drug absorption mechanisms. The examination consists of multiple-choice and descriptive questions, totaling 75 marks over a duration of 3 hours.

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Dipanshu Kumar
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284 views1 page

Bpharm 6 Sem Biopharmaceutics and Pharmacokinetics Bp604t Jun 2024

This document outlines the structure of the BPHARM (Semester VI) Theory Examination for Biopharmaceutics and Pharmacokinetics, scheduled for 2023-24. It includes three sections with various questions covering topics such as drug elimination, pharmacokinetic models, and drug absorption mechanisms. The examination consists of multiple-choice and descriptive questions, totaling 75 marks over a duration of 3 hours.

Uploaded by

Dipanshu Kumar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Subject Code: BP604T


0Roll No: 0 0 0 0 0 0 0 0 0 0 0 0 0

BPHARM
(SEM VI) THEORY EXAMINATION 2023-24
BIOPHARMACEUTICS AND PHARMACOKINETICS THEORY
TIME: 3 HRS M.MARKS: 75

Note: 1. Attempt all Sections. If require any missing data; then choose suitably.

SECTION A

1. Attempt all questions in brief. 10 x 2 = 20


a. Define elimination and excretion of drug
b. Classify different pharmacokinetic models
c. What is IVIVC studies
d. Define renal clearance of drug
e. What are the different site for binding of drug in case of human serum albumin
f. What is apparent volume of distribution of drug
g. Draw a model for one compartment open model I V infusion

2
h. List out different non per oral route of absorption of drug

23
55

i. What is maintenance and loading dose in multiple dosing of drug

6.
_8

15
j. Explain the cause of non-linearity in case of absorption
P1

8.
4E

.5
SECTION B
52
P2

2. Attempt any two parts of the following: 2 x 10 = 20


|1
Q

a. Calculate the value of α,β and volume of distribution using Two compartment open
AM

model IV bolus using graph.


b. What are the different Pharmacokinetic methods used for the measurement of
bioavailability?
1
:3

c. Describe various pharmacokinetic and pharmacodynamic parameter used to


02

measure plasma concentration time profile of a drug


9:

SECTION C
24

3. Attempt any five parts of the following: 7 x 5 = 35


20

a. Enumerate the patient related factors affecting drug absorption from GIT.
n-

b. Calculate elimination rate constant and half-life using one compartment open model
Ju

I V bolus.
2-

c. What is the clinical significance of protein binding of drugs?


|1

d. Explain the different passive mechanism for absorption of drug with example.
e. What are the different non renal route of drug excretion?
f. How are steady state drug levels in case of multiple drug dosing calculated?
g. Describe the Michaelis-menten method of estimating different pharmacokinetic
parameters.

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QP24EP1_855 | 12-Jun-2024 9:02:31 AM | 152.58.156.232

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