Arunai college of Pharmacy – Tiruvannamalai Apr – Oct 2025 Batch
Lecture Note - Mr. Murugan, Lecture Plan
Associate Professor Medicinal Chemistry III
Arunai College of Pharmacy - Tiruvannamalai
Course Bachelor of Pharmacy Batch 2022 - 2026
Subject Medicinal Chemistry - III Semester 6th Semester
Subject Code BP601T Session Apr – Oct 2025
Name of the Teaching Faculty Mr. Murugan Effective On 21 – Apr - 2025
SUMMARY OF LECTURE PLAN 45 HOURS
S. No Date Lectures - Topics Cover Field of Discussion
1 Antibiotics History, Definition, Classification, Mechanism & Uses
2 β - lactam antibiotics Definition, Classification, Mechanism & Uses
3 History, Definition, Classification, Mechanism & Uses
Penicillin
4 Nomenclature, Chemistry, Degradation, SAR
5 History, Definition, Classification, Mechanism & Uses
Cephalosporin
6 Nomenclature, Chemistry, Degradation, SAR
7 β - lactamase inhibitor Definition, Classification, Mechanism, Use & Drugs
8 Monobactam Definition, Classification, Mechanism, Use & Drugs
9 Definition, Classification, Mechanism, Use & Drugs
Tetracyclines
10 Nomenclature, Chemistry, Degradation, SAR
11 Aminoglycosides Definition, Classification, Mechanism, Use & Drugs
12 Macrolide Definition, Classification, Mechanism, Use & Drugs
Definition, Chemistry, Mechanism, Use, SAR &
13 Chloramphenicol
Synthesis
14 Clindamycin Definition, Mechanism, Use & Drugs - Discussion
15 UTI Agents - Quinolones Definition, Classification, Mechanism, Use
16 Miscellaneous SAR, Drugs, Synthesis & Miscellaneous
17 Sulfonamides Definition, Classification, Mechanism, Use
18 SAR, Drugs, Synthesis
19 Anti-folate, Sulfone Folate Reductase inhibitor, Sulfones
20 Antimalarial agents Etiology of malaria, Definition, Classification
21 Quinolones Chemistry, SAR, Mechanism Uses & Drugs
Anti-folate Biguanides, dihyrotriazines & Pyrimethamine
22
Miscellaneous Artemisinin, Quinacrine, Atovaquone
23 Antitubercular Agents - Synthetic Definition, Classification, Mechanism, Use & Drugs
24 Antitubercular antibiotics Definition, Classification, Mechanism, Use & Drugs
1st sessional Exam
Arunai college of Pharmacy – Tiruvannamalai Apr – Oct 2025 Batch
Lecture Note - Mr. Murugan, Lecture Plan
Associate Professor Medicinal Chemistry III
S. No Date Lectures - Topics Cover Field of Discussion
25 Anti-viral Agents Definition, Classification, Mechanism, Use & Drugs
26 Definition, Classification, Mechanism, Use & Drugs
27 Definition, Classification, Mechanism, Use & Drugs
28 Antifungal Agents - antibiotics Definition, Classification, Mechanism, Use & Drugs
29 Synthetic antifungal agents Definition, Classification, Mechanism, Use & Drugs
30 Anti-Protozoal Agents Definition, Classification, Mechanism, Uses & Drugs
31 Anthelmintics Definition, Classification, Mechanism, Uses & Drugs
32 Drug Design Introduction of drug Design
33 QSAR Definition, Concepts, Application
34 Physiochemical parameter Partition co-efficient, Hammet electranic parameter
35 Taft steric parameter, Hansch Analysis
36 Pharmacophore Modeling Definition, Concepts, Types, Application
37 Molecular Docking Definition, Concepts, Types, Application
38 Definition, Concepts, Types
Prodrug
39 Application
40 Combinatorial Chemistry Definition, Concepts, Types, Application
41 Solid Phase Synthesis Definition, Concepts, Application
42 Solution Phase Synthesis Definition, Concepts, Application
2nd sessional Exam
43 Discussion & revision
44
45
Prepared By Checked by Approved by
Subject Staff Class in-charge Principal
Arunai college of Pharmacy – Tiruvannamalai Apr – Oct 2025 Batch
Lecture Note - Mr. Murugan, Lecture Plan
Associate Professor Medicinal Chemistry III
Arunai College of Pharmacy - Tiruvannamalai
Course Bachelor of Pharmacy Batch 2022 - 2026
Subject Medicinal Chemistry - III Semester 6th Semester
Subject Code BP607P Session Apr – Oct 2025
Name of the Teaching Faculty Mr. Murugan Effective On 21 – Apr - 2025
SUMMARY OF PRACTICAL PLAN 4HOURS / WEEK
S.
No Experiment Thursday Friday Monday Tuesday
Preparation of Drugs Assay of Drugs Batch A Batch B Batch C Batch D
1 Introduction
7- OH, 4- CH3
2 Coumarin Chloroquine
2 Chlorobutanol Chlorpheniramine
3 Hexamine Dapsone
4 Sulphanilamide Benzyl Penicillin
5 Triphenyl Imidazole Isoniazid
6 Tolbutamide Metronidazole
7 Sessional Practical Exam - I
Preparation of medicinally important compounds or Intermediates by Microwave irradiation technique
8 Paracetamol Triphenyl Imidazole
Drawing structures and Reactions using ACD/Chemsketh
9 Structure
10 Reactions
Determination of physicochemical properties such as logP, clogP, MR, Molecular weight, Hydrogen bond
donors and acceptors for class of drugs course content using drug design software like drug likelines
screening (lipinskies RO5)
11
12
13 Sessional Practical Exam - II
Prepared By Checked by Approved by
Subject Staff Class in-charge Principal
