MTRD Medicin
MTRD Medicin
Lo. 1
Use basic knowledge of organic chemistry
Organic chemistry
Organic chemistry is the area of chemistry that involves the study of carbon and its
compounds. Carbon is now known to form a seemingly unlimited number of compounds.
The uses of organic compounds impact our lives daily in medicine, agriculture, and
general life.
is the study of carbon and the study of the chemistry of life
the study of molecules containing the carbon-hydrogen (C-H) bond and their reactions.
is the study of compounds containing carbon with the exception of simple compounds
e.g. carbonates (CO3), carbon dioxide (CO2) and carbon monoxide (CO)
is the science of the arrangement, structure, properties and reactions of substances,
especially of atomic and molecular systems called organic compounds
deals with the compounds of carbon
Compounds derived from plants and animals became known as organic and those
derived from nonliving sources were inorganic
organic compounds
All organic compounds contain carbon in combination with one or more elements.
The hydrocarbons contain only carbon and hydrogen.
A great many compounds contain carbon, hydrogen, and oxygen, and they are
considered to be the major elements.
Minor elements in naturally occurring compounds are nitrogen, phosphorus, and sulfur,
and sometimes halogens and metals.
Properties
Organic compounds, in general, differ greatly from inorganic compounds in seven respects:
Organic compounds are
1. usually combustible
2. have lower melting and boiling points
3. usually less soluble in water
4. exist for a given formula called isomerism = Compounds having the same molecular formula
5. Reactions usually molecular rather than ionic
6. The molecular weights may be very high, often well over 1000.
7. serve as a source of food for bacteria.
Sources
Organic compounds are derived from l sources:
1. Nature: fibers, vegetable oils, animal oils and fats, alkaloids, cellulose, starch, sugars, etc
2. Synthesis: A wide variety of compounds and materials prepared by manufacturing processes.
3. Fermentation: Alcohols, acetone, glycerol, antibiotics, acids, and the like are derived by the
action of microorganisms upon organic matter
Drugs that we use for the healing of various illnesses are chemical compounds, either organic or
inorganic. Nevertheless, most drugs are based on organic structural features. Aspirin is a well-
known example.
Aspirin
analgesic drug
usages in some cardiovascular related diseases
structural simplicity and low cost
chemically known as acetylsalicylic acid, an organic molecule
The precursor of aspirin is salicin, which is found in willow tree bark
easily be synthesized from phenol using the Kolbe reaction
Aloe
Key Constituents
■ Anthraquinones (aloin, aloe-emodin)
■ Resins
■ Tannins
■ Polysaccharides
■ Aloectin= Phenyl pyrones Glycosides include aloenin and aloenin B.( B
CLOVE
Key Constituents
■ Volatile oil containing eugenol (up to 85%), acetyl eugenol, methyl salicylate, pinene, vanillin
■ Gum
■ Tannins
Key Actions
■ Antiseptic ■ Prevents vomiting
■ Carminative ■ Antispasmodic
■ Stimulant ■ Eliminates parasites
■ Analgesic
Ginger
Key Constituents
■ Volatile oil (about 1%) containing alpha-pinene, cineole, linalool
■ Sesquiterpene lactones (galangol, galangin)
■ Diterpenes
■ Flavonoids
Carbohydrates Starch (major constituent, up to 50%).
Lipids 6–8%. Free fatty acids (e.g. palmitic acid, oleic acid, linoleic acid, caprylic acid,
capric acid, lauric acid, myristic acid, pentadecanoic acid, heptadecanoic acid, stearic
acid, linolenic acid, arachidic acid, triglycerides, phosphatidic acid, lecithins;
gingerglycolipids
Key Actions
■ Warming digestive tonic ■ Antibacterial
■ Carminative ■ Antifungal
■ Anti-inflammatory ■ Antitumor
■ Anti-emetic
7
LO2: Identifying medicinal plants in their natural and dry state
Definition of terms
Traditional medicine (TM): It is the sum total of the knowledge, skill, and
practices based on the theories, beliefs, and experiences indigenous to different
cultures
Complementary medicine (CM): The terms complementary medicine or
alternative medicine refer to a broad set of health care practices that are not part
of conventional medicine and are not fully integrated into the dominant health-care
system.
Allopathic medicine: a system in which medical doctors and other health care
professionals treat symptoms and disease using drugs, radiation, or surgery.
Complementary/Alternative medicine (CAM):-CAM is a group of diverse
medical and health care systems, practices, and products that are not generally
considered to be part of conventional medicine
Traditional medicine refers to
the knowledge, skills and practices based on the theories, beliefs and experiences
indigenous to different cultures, used in the maintenance of health and in the prevention,
diagnosis, improvement or treatment of physical and mental illness.
is often termed alternative or complementary medicine in many countries. Herbal
treatments are the most popular form of traditional medicine and 70% to 80% of the Region
has used a form as primary health care.
Main Popular System of TM/CAM
Traditional Chinese Medicine Homeopathy
Indian Ayurveda Medicine Chiropractic
Arabic Unani Medicine
Categories of TM
Medication
Medicinal plants Animal materials
Mineral materials
Non-medication
Acupuncture: treatment derived from ancient Chinese medicine in which fine needles are
inserted at certain sites in the body for therapeutic or preventative purposes
Ayurveda :
belief that health and wellness depend on a delicate balance between mind, body
and spirit
believed that the body constitution is made up of a combination of five universal
elements; space, air, fire, water and earth
Herbalists
Traditional birth attendants
Bone-setters
Traditional medicinal ingredient dealers
Traditional psychiatrists
Practitioners of therapeutic occultism
Physical, mental and spiritual therapies
8
Traditional Medicine vs Allopathic Medicine
Types of CAM
Major domains of CAM (non allopathic)
• Manipulative and body-based practices:- chiropractic or osteopathic manipulation or
massage therapy
• Energy medicine:- therapies affecting body energy fields (qi gong, healing
touch, Reiki) or unconventional use of electro-magnetic fields.
• Mind-body medicine:- techniques designed to enhance the mind's capacity to affect
bodily function and symptoms e.g. meditation, mental healing.
• Biologically based practices:- herbs and other dietary supplements
• Alternative medical system
Allopathic medicine:
a system in which medical doctors and other health care professionals treat
symptoms and disease using drugs, radiation, or surgery.
Allopathic medicine refers to the broad category of medical practice that is
sometimes called Western medicine, biomedicine, scientific medicine, mainstream
medicine or modern medicine or conventional medicine.
This system was developed in the Western countries.
In this system drugs (tablets, capsules, injections, tonics etc.) are manufactured
using synthetic chemicals and / or chemicals derived from natural products like
plants, animals, minerals etc.
This system also uses modern equipment for diagnosis, analysis, surgery etc.
Medicines or drugs of this system are often criticized for its treatment of the
symptoms rather than the cause of the disease, harmful side effects of certain drugs
and unaffordable to poor people due to the high cost and treatment
9
More affordable than conventional medicine. emphasizes therapies that improve quality
Promote natural healing. of life
Strength in immune system. prevent disease,
Easier to obtain than prescription medicine. address conditions that conventional
Stabilizes hormones and metabolism. medicine has limited success in curing,
Fewer side effects. such as chronic back pain and certain
It is cost effective. cancers
safer and more natural
Disadvantages of herbal medicines
– Herbal medicines are often not potent enough to treat severe illnesses by
themselves, except sometimes with a long-term course.
– Diseases may be drawn out unnecessarily when self-prescribed herbal drugs are
taken improperly.
– The improper long-term use of certain herbal preparations, such as the pyrrolizidine
alkaloid-containing herb comfrey, can lead to severe side effects.
Teanicides Blindness & changes in CNS function took over dosage of Hygeia abyssinica.
Traditional healers may delays in the treatment of communicable diseases such as TB
Other harmful practices: female genital mutilation, uvulectomy, and milk tooth extraction
Recognition of Highly poisonous plants of Ethiopia
No country in Africa enjoys as great a diversification of geology, land forms, soils, and climate as
Ethiopia.
There are more than forty five vegetation types where forests, savannas, woodlands, steppes
and grasslands comprise 75% of the vegetation cover.
possesses one of the richest floras in Africa, with no less than 7.000 species of Pteridophytes
and Spermatophytes.
is one of the primary centers of origin of many of the world's cultivated crops, e.g. , wheat,
barley, teff, coffee, peas, okra, sorghum, millets, lentils.
flora is 35% endemic and is an independent floristic region closely allied to the flora of tropical
East Africa and Central Africa.
Poisonous plants
produce their toxic effects after being ingested and/or absorbed by animals which include
physical upset, loss of productivity and death.
when pasture is dry while most poisonous plants remain green all the year round.
Remain green and attractive for hungry and thirsty animals
include both herbaceous and woody species.
The art of preparing and administering poisons is equally as rich in lore as more conventional
medicine. Ethiopians possess an extensive knowledge of poisonous plants and the art of preparing
poisons from diverse sources. Poisonous preparations applied to weapons were probably first used
for hunting game and arrow poisons are common in East, Central and West Africa.
A number of poison plants are used in Ethiopia
Euphorbia spp = Cassava
Bitter cassava has large quantities of highly toxic glycosides and has caused many deaths,
and must be carefully soaked and cooked before it is safe to eat
Acokanthera schimperi (Carrissa schimperi) = merz =Qeraro
used in the preparation of arrow poisons
Calotropis procera = tobbeya= Falfala Adal= Galiiloo
Its latex is generally considered poisonous both to humans and stock.
The latex causes heart paralysis
Ariti is used to relieve stomach pains. The juice of the crushed leaves is mixed with
water or honey and is administered orally.
It is also used to clean containers perhaps because of the pleasant odor. The plant
is harvested when in the flowering stage.
Veronia amygdalina Del. grawa (A)= hobichaa=ebicha
The dried flower is used to treat
stomach disorder.
used in the treatment of malaria.
leaves are sometimes used in the preparation of the local drink, tela in place of gesho
cooked leaves arre edible.
Catha edulis = khat = jimaa
The root is used in some parts of Africa as a remedy for influenza, for stomach troubles and
diseases of the chest
The leaf has an inebriant narcotic and release from fatigue and hunger
Maytenus ovatus = kambolcha
source of anti-cancer drug
leaf decuction is used to control external parasites both in domestic animals and in humans
Lepidium sativum L.= fetto (A) = shufu
It has the following uses for
The ripe, dried seeds are ground into a fine flour and mixed with water to use as a drench
for stomach disorders of livestock.
A paste is made of the seed-flour and water and used on chapped lips, sunburn, and other
sking disorders.
The flour is mixed with honey and taken as a treatment for amoeba.
The paste is rubbed onto the skin to repel mosquitoes and other insects.
In times past, the paste was rubbed onto the skin by warriors for warmth during cold nights.
fetto, tukur-asmu (Nigella sativa) and salt are ground together to make a thick dough and
allowed to ferment for seven deys. One teaspoon of this is taken once a day for stomach
used in the treatment of a disease of cows' udder called "gigo" solution is massaged onto
the surface.
In humans, it is used in the treatment of acute side pains which often result from overeating
Juniperus procera Hochst ex Engl. tidh = gattira
used in the treatment of stomach worms.
Ajuga remota Benth= akorarchigne= Harmaguusaa
An extract of the leaves is used
against dysentery
against swelling of the legs
for the treatment of high blood pressure.
make babies stop suckling by applying to the teats when such is desired by the mother
Croton macrostachyus Hochst. bissana (A)= Bakanissa,
The fruits and a decoction of the roots are used as e medicine against venereal diseases
and seeds are used to cause abortion.
The pulverized bark mixed with kosso (Hagenia abyssinica, Rosaceae) is a very
effective purgative and vermifuge
The seeds and the resins are toxic and are used as a fish poison
The paste is eaten with bread for at least three day so Plenty of milk is drunk but meat
and oily food must be avoided
Ricinus communis L. = gullo (A)= kobo = castor bean
seed oil is used as a mild purgative and widely used in tannery work.
Thymus schimperi Ron. = tossigne (A)
used in the control of gonorrhea.
When it is added to boiling water and drunk, it is used against cough and liver disease.
Some prefer to smoke it as a cigarette.
is used to flavor tea or drunk alone as tea.
Tamarindus indicus L. = homar (A)= roka = tamarind-hendi (Arabic)
The fruit is used as refrigerant, digestive, carminative, laxative, and anti- scorbutic.
With sugar and water, the fruit makes a colling drink and is use in place of lime juice.
The leaves are high in acid and are used as poul
tices in boils.
The seeds are used against diarrhea.
The over-ripe fruit is used to clean copper and brass perhaps because of acidity.
Linum usitatissimum L.= telba (A)= flax-seed (Eng) = Qonxar
. It is generally used as a demulcent laxative drink.
Cooked seeds are placed on wounds to cause quicker healing. A wound with a bullet
inside is stuffed with the same and wrapped. After a given time period, the flax "draws'
the bullet to the surface where it can be extracted easily.
Phytolacca dodecandra L'Hérit. = endod (A) = handode (G)
The decoction of the root (1 in. long) is used in the treatment of genorrhea.
the root to cause abortion. The dosage must necessarily be regulated to avoid death of the
woman.
use in the control of schestosomiases (bilharzia) by destroying the snail (Lemma, 1971).
Rumex nervousus Vahl = embwacho (A) = dengego
The seeds and dried plant parts are used to flavor local drinks such as areke and tej.
The boiled or roasted roots are used in the treatment of gonorrhea
Zingiber officinale = Roscoe = zingibil
The rhizome, as much as it is a common spice in the preparatlon of traditional foods,
medicine for stomach cramps
chewed or masticated with feto for the treatment of stomach disorders
The whole fresh plant is used to dress wounds and sores
Clerodendrum myricoides = missiritch= Tiiro
• Fruits vary
Preparation of Herbs
Good collecting
General Advice
Harvesting medicinal herbs requires careful planning to ensure the parts are processed in peak
condition and fast enough to retain their active ingredients.
Equipment
use a wooden tray or open basket for collecting herbs
Always cut with a sharp knife or scissors to minimize damage to plant
Wear gloves if gathering prickly or allergenic plants
What to Look For
Collect material from healthy plants, free from insect damage and pollution.
discard damaged plants because they can lead to disease or decay in dried plant material
Do not mix cut plant material to avoid mistakes in identification
When to Harvest
Gather herbs in dry weather, preferably on a sunny morning after the dew has evaporated.
Picking when the plant is at its peak of maturity ensures that it will have a high
concentration of active constituents.
Leaves are best collected as they open during the spring or summer months,
flowers as they start to bloom,
fruit and berries just as they become ripe,
roots in the autumn once the plant has drawn its vitality back beneath ground
Bark must be gathered with great care if the shrub or tree is to survivein most cases,
harvest it in spring or autumn.
Roots and rhizomes: Best collected October to February, when the plants are more
vigorously storing food in their underground organs.
Processing Quickly
Only collect plant material that you will be able to use or process immediately after
harvesting. This is because
o fresh plant material deteriorates very quickly and the medicinally active constituents
are often the first to be affected.
o aromatic herbs can lose their volatile oils within hours
o Salad leaves and culinary herbs are best eaten right away to make the most of their
nutrients, although they can be stored for a few days in a plastic bag filled with air
in a refrigerator.
Proper drying of the medicinal plants
When medicinal plant materials are prepared for use in dry form, the moisture content of
the material should be kept as low as possible in order to reduce damage from mould and
other microbial infestation..
Medicinal plants can be dried in a number of ways:
1. in the open air (shaded from direct 5. drying ovens/rooms and solar dryers;
sunlight) 6. by indirect fire;
2. placed in thin layers on drying frames, 7. baking;
3. wire-screened rooms or buildings; 8. microwave;
4. by direct sunlight, if appropriate; 9. infrared devices
When possible, temperature and humidity should be controlled to avoid damage to the
active chemical constituents.
The method and temperature used for drying may have a considerable impact on the quality
of the resulting medicinal plant materials. For example,
o shade drying is preferred to maintain or minimize loss of color of leaves and
flowers;
– Control temperature (normally 40ºC) & ventilation (allows dry air to replace wet
air).
5. Vacuum Drying
Steam-heated ovens: pump used to extract air
Low pressure to ensure rapid and complete drying
Expensive method
Reserved for expensive herbs and which cannot be sufficiently dried through other
methods.
General Drying Techniques
a) Leaves/Herbs:
– 40-50º C
– Maintains good colour
– Without over drying herbs
– Normally destalked first
– Best dried for short periods of time only à prevents shrivelling and discolouration
– Leaves may be bleached through the drying process à best dried in dark
b) Roots/Rhizomes
– Washed
– Sliced
– Dried between 30-65ºC
– Temperature too high: forms a tough crust on the outside à preventing the further
drying of deeper tissue
– Thick organs may require long periods of drying (10days-3weeks) to avoid mould
growth.
6. Flowers
Normally destalk before drying
Flowers may also be bleached when dried à best dried in dark.
General Drying Techniques:
Volatile oil containing herbs
Air-Dried at very low temperature
Avoid volatilization of oil contents
Should also be dried separately from other herbs.
7. Fruits & Seeds
Normally partially dry before harvesting
May be air-dried afterwards
Seeds are normally separated from the fruits before drying
Fruits are normally left whole
Some fruits (cardamom) rupture due to excessive heat.
8. Bark
Occasionally requires the removal of the outer layers
Storing Herbs
It is vital to store dried herbs properly or they will not last.
Leaves, flowers, roots, and other parts should be stored
o in sterilized, dark glass containers with airtight lids
o new brown paper bags, which must be kept dry and away from light.
Metal and plastic containers are inadvisable because they may contaminate the herb.
If stored in a cool, dark place, herbs can be kept for about 12 months after harvesting.
Herbs frozen in plastic bags can be used for up to 6 months.
Label the container with the herb, source, date of harvesting, and strength of preparation if
appropriate.
Watch out for insect infestation
Dirt and other foreign substances should be removed
Many medicinal plants are seasonal, some not easily accessible, available only in deep
forests or mountain peaks.
If washing is needed, it should be done quickly to minimize deterioration and loss of active
substances.
As a rule, all parts of the plant collected should be dried as soon as possible to avoid
unnecessary waste of the drug materials through natural processes of denaturation, decay
and fungal attacks.
Storage materials
The dried plant materials should be placed in
o plastic containers
o tightly covered bottles
o brown colored bottles are preferred as they minimize deterioration due to sunlight
o Dry charcoal (separated from the medicinal plant) may be placed inside the bottles
to absorb moisture.
o The storage place should be
dry,
well-ventilated, and
spacious, lest fungi and insects may invade rampantly
o Dry drug materials after proper processing can be kept in large open wooden
shelves.
o Materials rich in volatile oils are advised to be kept in airtight containers.
o If all factors are favorable, prepared drugs can be used even after years of storage.
Store in a cool (not cold), dark place, out of the reach of children.
Discard after the expiration date.
Factors that can reduce the shelf life of herbal medicines:
Exposure to air (keep in airtight bottles)
Humidity
Heat
Light (leading to oxidation-related decomposition)
Lo 4: Communicating knowledge of herbal medicine philosophy, principles and
practice
(a) The body is made up of the four basic elements that have different temperaments, that is,
1) earth (cold), 3) water (wet), and
2) air (hot), 4) fire (dry)
(b) Mixing and interactions of the four elements result in the creation of new compounds
having new Mizaj (temperament), that is,
1) hot wet, 3) cold wet, and
2) hot dry, 4) cold dry.
(c) The body has simple and compound organs that receive their nourishment through four
Akhlaat (humors),
1) Dam (blood), 3) Safra (yellow bile), and
2) Balgham (phlegm), 4) Sauda (black bile).
(d) Each humor has its own temperament:
1) blood is hot and moist, 3) yellow bile is hot and dry, and
2) phlegm is cold and moist, 4) black bile is cold and dry.
(e) Every healthy person attains a temperament according to the preponderance of the humors
in the body. The temperament of a person may be
1) Sanguine = too much blood
2) Phlegmatic = too much phlegm
3) Choleric = too much yellow bile
4) melancholic = too much black bile
Health represents a balance of the four humors and functions of the human body.
1) To maintain an optimal balance, there is a power of self-preservation or adjustment
called Quwwat-e-Mudabbira (medicatrix naturae) in the body.
A disease is a result of a quantitatively or qualitatively imbalance in the equilibrium of the
humors
The duty of physician is to determine the cause of the underlying imbalance of humors, so that it can be
corrected and disease can be cured.
Imbalance of humors may be due to
1) external factors such as an injury, incorrect diet, environmental factors, and so on,
2) internal factors such as improper digestion, or both.
External environmental factors and daily lifestyle can affect the human body, for example,
1) air quality,
2) food and drink,
3) movement and rest,
4) sleep and wakefulness, and
5) emotions
It is believed that each of these five factors must be balanced in terms of quality, quantity,
and sequence in order to sustain good health.
Imbalance of humors tends to occur as a result of
Imbalances of humors tend to occur in four ways:
1. Thinning of humor (Riqqat-e-Khilt): The consistency of humor becomes thinner.
2. Thickening of humor (Ghilzat-e-Khilt): The consistency of humor becomes thicker.
3. Plethora (Ghalba-e-Khilt): The humor becomes over active/ hyperactivity
FACE INSPECTION
CHANGES IN THE EXTERNAL FORM OF THE FACE
Facial swelling and white coloration is spleen(rajjijji) and kidney vacuity.
Swelling with hot pain, numbness or itching is wind(maruu fashan) evil(hama) heat toxin.
Sudden facial swelling in enduring or serious disease is a symptom of earth being used up
by the spleen.
Cheek swelling -Sudden swelling up of the face and cheeks, fever, red face, swollen and
painful throat, or no throat pain but swollen cheeks accompanied by deafness, is mumps, a
warm toxin pattern.
Mouth
o Ulceration of the mouth and tongue usually is heat evil (stomach fire or food accumulation
generating heat).
o Deviated mouth and eyes and stirring of the lips are wind stroke.
o Clenched jaw and inability to speak are tetany. P
o U
o lips with green-blue color and convulsive spasms indicate liver wind overwhelming the
spleen.
o White spots or patches like snowflakes in the mouth of infants are goose-mouth sores which
are generally due to depressed heat in the spleen channel.
o If in disease there is darkness around the lips, the opening of the mouth is like a fish's
mouth and air is exhaled but not inhaled, this is a critical sign of spleen expiry
o Swollen lips and burnt black teeth are expiry of the spleen and kidney
o Open mouth = Here the mouth opens but does not close. This governs vacuity.
o Clenched jaw =Here the mouth closes but there is difficulty in opening. This governs
repletion.
o Pursed = Here the upper and lower lips have a pursed-together form. This indicates that, in
the battle between evil and right, right is debilitated and evil is prevailing.
o Deviated = Here the left and right [sides of the mouth
o are in a condition of [one being] relaxed and the other tensed. The channel sinews are
stretched. The tense side shows the right qi and the relaxed side shows the evil qi.
o Mouth biting = Here there is a slight movement, but the teeth do not open; the kidney is
being vanquished, the disease has thrust out from the stomach channel.
INSPECTION OF VOMIT
Vomit comes from the stomach.
Stomach cold causes the vomit to be relatively clear and thin without an odor.
Food stagnation causes the retching of putrid smelling food dregs (food retention).
Evening food vomited at dawn and dawn food vomited in the evening, and vomiting of
retained food indicates stomach reflux.
Damage to the stomach network vessels causes the vomiting of blood.
Vomiting of yellow-green bitter water is usually from liver and gallbladder damp-heat.
A. Diet therapy
For old people
Recommended that they should be given food
o in small amounts at a time and that they can have two to three meals a day
o divided according to the digestive capacity
o general condition of the old person in question
o fruits, such as figs and prunes
o Some laudable nutrition may be allowed at bedtime
o Milk is good for the aged, being nutritious and humectant in nature
o with a laxative action are most appropriate for the elderly
avoid any gross aliment
o all hot, sharp or desiccative foods
o dishes made with vinegar, salt, hot aromatics, seasonings and pickles
B. Bloodletting
1. Cupping (Hijamah)
is the sucking of blood by cupping
is a method used for local evacuation or diversion of morbid blood in which a horn is
attached to the surface of the skin of the diseased part through negative pressure created by
vacuum.
The vacuum is created by the introduction of suction.
Cupping is of two types;
2. wet cupping, that is, cupping with bloodletting and
3. dry cupping, that is, cupping without bloodletting.
In the wet cupping,
o the skin site is shaved, cleaned, and marked by placing the mihjamah such as a bull
horn on the site and sucking the mouth end of the horn to mark the site for extraction
o The horn is removed and superficial incisions are made within the marked area. Then,
the horn is reapplied and the horns mouthpiece is vigorously sucked.
o Blood accumulates within the horn.
o After that, the wound is cleaned with dry cloth and either left uncovered or herbal
powder is applied.
o The patient is instructed to keep the wound dry for one day.
For each complaint, there is a specific site for hijamah. For instance,
o for headache, the location is behind the head
o For chest pain, the location is on the shoulder, dorsally.
Bloodletting (Fasd)
o is phlebotomy or venesection,
o is rarely practiced nowadays in the Arab world
o is a procedure in which an incision is made to any of the superficial veins, and blood
containing waste material is allowed to flow
o removes excess humors in the same proportion as present in the blood vessels,
abnormal humor, or both.
o applied for purification of vitiated humors in meningitis, pneumonia, pleurisy, sciatica,
gout, rheumatic arthritis, diphtheria, piles, and amnesia
o 30 blood vessels as suitable for venesection
o 16 vessels in the head,
o 5 in each arm and hand, and
o 3 veins in each leg and foot
Leech Therapy (Taleeq)
o is a unique method of removal of bad matters from the body
o is better than cupping for drawing the blood from deep tissues
o Leave leeches in fresh water for a day and a night until they are hungry and nothing
is left in their bellies. Scrub the afflicted part until it is flushed; and then place the
leeches on it. When they are full they will fall off..
Used in
Microsurgery
o reduce blood coagulation (they produce an anticoagulant molecule called hirudin),
relieve venous pressure from pooling blood (venous insufficiency), and
o stimulate circulation in reattachment operations for organs with critical blood flow,
such as eyelids, fingers, and ears, in reconstructive surgery
Side effect
o prolonged bleeding, which can easily be treated,
o allergic reactions and bacterial infections may also occur
Cauterization (Kayy)
o burning of part of a body to remove or close off a part of it in a process
o destroys some tissue, in an attempt to mitigate damage, remove an undesired growth, or
minimize other potential medical harmful possibilities such as infections when
antibiotics are not available
o useful in stopping severe blood loss to close amputations and in preventing infections
WATER THERAPY
Water is a natural gift and is a part of the act of purification
Water from the Zamzam well in Mecca is considered holy, and millions of Muslim
believers use it to cure diseases.
The Prophet (SAW) described the water of the well of Zamzam saying,
o It is blessed! It is a kind of food and cure for illness.
o So, if you drink it in order to be cured of illness, God cures you; if you drink it in
order to satisfy your appetite, God satisfies your appetite for you; and if you drink it
in order to quench your thirst, God quenches your thirst for you. It was dug up by
Gabriel and provided by God to Ishmael to drink.
Thermal and Mineral Waters.
o cure a variety of illnesses
o heart diseases
o joint disorders
o respiratory inflammation
o and kidney stones
o relax muscles and the mind
o provide relief from muscular and joint pains
o heal infections
o Naturally occurring hot springs were particularly valued in colder climates
o considered curative due to their physical and chemical properties and also through
psychological effect
o Water containing hydrogen, sulfur, carbon dioxide, and bromides are useful
as a tranquilizer and a relaxant.
o waters are radioactive and contain high levels of iodides, iron, calcium, and
magnesium and are useful for the body as a whole.
o mineral water exerts an effect on
o the immunological and neuropeptidergic systems of the skin beyond the
antibacterial, antifungal, and keratolytic effects
o dermatological therapy through its hydrating, cooling, and cleansing effects
and as a vehicle for more effective delivery of active agents
SPIRITUAL THERAPY
o Spiritual medicine refers to the belief in a spiritual, ethical, or psychological cure for
diseases that may have physical or mental origin.
o Rhazes wrote al-Tibb al-Ruhani (Spiritual Medicine), which has been translated into
English as The Spiritual Physick of Rhazes.
Fasting
o means of providing the ideal conditions necessary for the repair of bodily damages and
for the elimination of toxins
o purifies the body and soul by feeling hunger and thus sympathizes with those who are
hungry and cannot afford to buy food
o during Ramadan every year includes meditation, contemplation, and cogitation
Siwak or Miswak
o oral hygiene is essential for a healthy body
DRUG THERAPY
o The drugs may be derived from plants, minerals, or animals.
Drug Temperament
o every drug has its specific temperament based on its ingredients.
o classified into five classes:
1. hot,
2. cold,
3. dry,
4. wet, and
5. sometimes neutral
A drug may be hot and dry, hot and wet, cold and dry, or cold and wet.
A drug used in a given pathological condition should have temperament opposite to the
prevailing temperament of the affected organ.
Potency of Drugs
1. The concept temperament by Hippocrates and Galen discussed only the
qualitative and not the quantitative nature of the temperaments of simple drugs
(single plants).
2. The term degree was considered as a sensation effect of a drug without any
quantitative scale based on scientific methods.
3. The four degrees of each drug temperament, which represent the strength of the
drug, or maybe, the harmacological and toxicological effects,
1. 1st degree understood as mathematical sum of each degree
2. second degree meant double of first degree
3. third degree meant three times of the first degree, and so on.
4. temperament of a drug, according to Al-Kindi, means the chemical properties,
toxicity, drug interactions, mechanism of action, and efficacy.
5. The temperaments were determined following their physiological action
examined and observed by physicians, animal tests, and clinical trials using both
single and compound drugs.
Hot drugs, for instance, indicate
o the first and second degrees hot drugs that can stimulate and enhance body
temperature / activating basic metabolic rates
o The third hot degree is quite toxic
o the fourth one is highly toxic with severe side effects and should be
controlled using ingredients with antidote or antagonistic effects
Herbal Remedies.
o forms
o crude forms
o herbal teas,
o syrups,
o infusions, and
o powders in the treatment and prevention of diseases.
SURGERY
Abu al-Qasim al-Zahrawi (Albucasis) born in 936 in Zahra, Cordoba (Andalusia), is regarded as
the pioneer of modern surgery who contributed greatly to the discipline with his Kitab al-Tasrif
LO 5. Manufacturing herbal medicines according to pharmacy guidelines
Extraction: is the separation of medicinally active portion of plants by using selective solvent and
suitable methods of extraction
Methods of Extraction of Medicinal Plants
Infusions
Macerating for a short period of time with cold or boiling water
It is made in a similar way to tea, using either a single herb or a combination of herbs, and
may be drunk hot or cold
Standard Quantity
CUP 1 tsp (23 g) dried or 2 tsp (46 g) fresh herb (or mixture of herbs) to a cup of water
(this makes 1 dose)
POT 20 g dried herb or 30 g fresh herb (or a mixture of different herbs) to 2 cups
(500 ml) of water
1. Place the herb in the strainer of the teacup and place a strainer in the cup. Fill the cup with
freshly boiled water.
2. Cover the cup with the lid and infuse for 510 minutes before removing thetea strainer.
Add a tea spoon of honey to sweeten, if desired.
Pot Infusion
Warm the pot, then add the herb. Pour in water that has just boiled, replace the lid, and infuse for
10 minutes.
Strain some of the infusion into a cup. A teaspoon of honey may be added if desired.
1. Place the herb in a clear glass jar. Pour in oil until it completely covers the herb, close the jar, and shake well.
Place the jar in a sunny spot, such as on a windowsill, and leave for 26 weeks.
2. Pour the oil and herb mixture into a jelly bag, secured to the rim of a jug or bowl with string (or use a wine press as
pictured above in hot infused oils). Allow the oil to filter through the bag.
3. Squeeze out the remaining oil from the bag. Pour the infused oil into dark glass bottles, label, and store. Alternatively,
repeat the whole process with the infused oil and fresh herbs
Decoctions
simmering these tougher parts in boiling water
Boiled in a specified volume of water for a defined Time
Fresh or dried plant material cut or broken into small pieces before decocting. Like
infusions, decoctions can be taken hot or cold.
made using roots, bark, and berries, but sometimes leaves and flowers
Standard Quantity
20 g dried or 40 g fresh herb (or mixture of herbs) to 3 cups (750 ml) cold water, reduced to about
2 cups (500 ml) after simmering (this makes 34 doses)
Procedure
1. Place the herbs in a saucepan. Cover with cold water and bring to a boil. Simmer for about
2030 minutes, until the liquid is reduced by about one-third.
2. Strain the liquid through a sieve into a jug. Pour the required amount into a cup, then cover
the jug and store in a cool place.
Maceration :
Solid ingredients are placed in a closed container with solvent and allowed to stand for at
least 3 days (3 - 7 days) with frequent agitation
Tinctures
Tinctures are made by soaking an herb in alcohol. This encourages the active plant constituents to
dissolve, giving tinctures a relatively stronger action than infusions or decoctions. They are
convenient to use and last up to two years.
Alcohol-reduced Tinctures
Alcoholic tinctures should sometimes be avoided, for example during pregnancy or a gastric
inflammation. Adding 1 tsp (5 ml) of tincture to a small glass of almost boiling water and leaving it
for 5 minutes allows the alcohol to evaporate. To make nonalcoholic tinctures, replace the alcohol
with vinegar or glycerol.
Tincture Ratios
Tinctures are made in different strengths, expressed as ratios. Example, a 1:5 ratio(1 part herb to 5
parts alcohol)
Standard Quantity
200 g dried or 300 g fresh herb chopped into small pieces to 1 quart (1 liter) alcoholvodka of
3540% alcohol is ideal, although rum hides the taste of bitter or unpalatable herbs
Procedure
1. Place the herb in a large, clean glass jar and pour on the alcohol, ensuring that the
herb is covered. Close and label the jar. Shake well for 12 minutes and store in a cool
dark place for 1014 days, shaking the jar every 12 days.
2. Set up the wine press, placing a muslin or nylon mesh bag securely inside. Pour in the
mixture and collect the liquid in the jug.
3. Slowly close the wine press, extracting the remaining liquid from the herbs until no
more drips appear. Discard the leftover herbs.
4. Pour the tincture into clean, dark glass bottles using a funnel. When full, stopper with a
corkor screw top and label the bottles.
Syrups
Honey and unrefined sugar are effective preservatives and can be combined with infusions or
decoctions to make syrups and cordials. They have the additional benefit of having a soothing
action, and therefore make a perfect vehicle for cough mixtures as well as relieving sore throats.
With their sweet taste, syrups can disguise the taste of unpalatable herbs and are therefore greatly
appreciated by children.
A syrup is
made with equal proportions of an herbal infusion or decoction and honey or unrefined
sugar.
When making an infusion or decoction for a syrup, it needs to be infused or simmered for
the maximum time to optimize its medicinal action.
Infusions should be infused for 15 minutes and decoctions should be simmered for 30
minutes.
Press the soaked herb through the strainer or sieve to remove as much liquid as possible.
Small amounts of neat tincture can be added to the cooled syrup to increase its
effectiveness.
Standard Quantity
2 cups (500 ml) infusion or decoction , infused or heated for the maximum time 500 g
honey or unrefined sugar
1. Pour the infusion or decoction into a pan. Add the honey or sugar. Gently heat, stirring constantly until all the honey or
sugar has dissolved and the mixture has a syrupy consistency. Remove from the heat and cool.
2. Pour the cooled syrup into sterilized glass jars using a funnel and store in a cool, dark place. Seal the jars with cork
stoppers, because syrups are prone to ferment and may explode if kept in screw-topped bottles
Ointments
Ointments contain oils or fats heated with herbs and, unlike creams, contain no water
Standard Quantity
60 g dried or 150 g fresh herb (or mixture of herbs) to 500 g of petroleum jelly or soft paraffin wax
1. Melt the petroleum jelly or wax in a glass bowl set in a pan of boiling water, or use a
double boiler. Add the finely cut herb and simmer for 15 minutes, stirring continuously.
2. Pour the herb mixture into a jelly bag secured to the rim of a jug with string, and allow
the liquid to filter through
3. Wearing rubber gloves, squeeze as much of the hot herb mixture as possible through the
bag into the jug.
4. Quickly pour the molten ointment into jars before it sets in the jug. Place the lid on each
jar without securing it firmly. When cool, tighten the lids and label.
Poultices
A poultice is a mixture of fresh, dried, or powdered herbs that is applied to an affected area.
Poultices are used to ease nerve or muscle pains, sprains, or broken bones, and to draw pus from
infected wounds, ulcers, or boils.
Standard Quantity
Sufficient herb to cover the affected area
1. Simmer the herb for 2 minutes. Squeeze out any excess liquid, rub some oil on the affected
area to prevent sticking, and apply the herb while hot.
2. Bandage the herb securely in place using gauze or cotton strips. Leave on for up to 3 hours,
as required
Percolation
It is continuous downward displacement of the solvent through the bed of crude drug
material to get extract.
Most frequently used to extract active ingredients in the preparation of tinctures and fluid
extracts.
A percolator (a narrow, cone-shaped vessel open at both ends) is generally used.
Concentration
• The extract contains huge solvent quantity and small amount of active molecule.
• Evaporate the solvent and enrich the active content
• under vacuum, Thin film evaporator, Freeze
Dos
Do establish clear performance expectations. .
Do focus on the facts
Do review patterns of problem behavior
Do write a specific plan
Do follow up
Donts
Dont generalize
Dont diagnose why the employee is performing poorly
Dont include your mental impressions or editorial comments
Dont embellish, stretch the truth, or call it something it isnt
Dont apologize
Practical Takeaway
documentation must:
follow policy and procedures
be clearly written so it can be understood
be accurate
be written down as soon as possible on the day it happened, not when you remember.
Appropriate and accurate records assist medication management and adequate documentation is an
important component of risk management and quality patient care.
Pharmacists
are encouraged to use reliable systems for documenting critical actions taken in relation to
patient counseling
should also record details of the circumstance and reasons after exercising professional
judgment.
The patient healthcare record should be created or updated in the pharmacy dispensing software at
time of dispensing, and the information confirmed as correct.
At the time of dispensing, the pharmacy dispensing software is used to:
record the details of all prescriptions dispensed
record any other legally required details of dispensing
generate a dispensing label
generate a repeat authorisation to attach to the duplicate of the prescription (if required).
The patient healthcare record may include:
patient details (e.g. date of birth)
medical history, including medical conditions, allergies and details of adverse reactions
medicines the patient is taking, including non-prescription medicines and complementary
medicines
details of any recent medication changes
relevant patient notes including brand preferences, details of services provided,
communication with prescriber, reasons for early or multiple repeats supplied, and follow-
up actions required
Patient privacy
Patient information collected and recorded during the dispensing process is confidential
Patient information should only be disclosed with the patients consent, unless required by
law.
Patient consent is required prior to disclosing patient information to a carer or authorised
representative collecting a medicine on behalf of the patient.
If the patient is unable to consent to the disclosure of their information, the pharmacist may
disclose information to another healthcare professional treating the patient, or responsible
person, providing the pharmacist is satisfied the disclosure
Labeling of Herbal medicines
Counseling
medicines. Counseling is a two-way communication process between the pharmacist and
the patient
It provides an opportunity to elicit the necessary information from a patient, provide the
required information to enable safe and effective use of medicines, and is the final checking
process to ensure the correct medicine is supplied to the correct patient
Objectives Of Performance
1. To provide learning, training, and development opportunities to employees.
2. To improvise individual job performance as well as methods and techniques of
measuring performance.
3. To review the ways of defining and agreeing of performance criteria of teams and
individual employees at the performance planning level
4. To assess commitment and motivational level to accept and realize performance
feedback in positive perspectives.
5. To incorporate change necessitated by external environment and affect over-all
performance improvement of the organization
Performance management as referenced on this page in a broad term coined by Dr. Aubrey
Daniels in the late 1970s to describe a technology (i.e. science imbedded in applications
methods) for managing both behavior and results, two critical elements of what is known as
performance.
Peer education is an approach to health promotion, in which community members are supported
to promote health-enhancing change among their peers. Peer education is the teaching or sharing of
health information, values and behavior in educating others who may share similar social
backgrounds or life experiences.
performance in their current role at work, to increase their effectiveness and productivity at
work. Generally, performance coaching derives its theoretical underpinnings and models
from business and sports psychology as well as general psychological theory.
Skills coaching. This form of coaching focuses on the core skills an employee needs to
perform in their role. Skills coaching provides a flexible, adaptive, just-in-time
approach to skills development. Coaching programmes are tailored specifically to the
individual and are generally focused on achieving a number of skill development objectives
that are linked to the needs of the organisation.
Career Coaching. Coaching activities focus on the individuals career concerns, with the
coach eliciting and using feedback on the individuals capabilities as part of a discussion
of career options. The process should lead to increased clarity, personal change and forward
action.
Personal or life coaching. This form of coaching provides support to individuals wishing
to make some form of significant changes happen within their lives. Coaches help
individuals to explore what they want in life and how they might achieve their aspirations
and fulfil their needs. Personal/life coaching generally takes the individuals agenda as its
start point.
Business coaching. Business coaching is always conducted within the constraints placed on
the individual or group by the organisational context.
Executive coaching: One to one performance coaching is increasingly being recognised as
the way for organisations and individuals to improve performance. By improving the
performance of the most influential people within the organisation, the theory goes that
business results should improve. Executive coaching is often delivered by coaches
operating from outside the organisation whose services are requested for an agreed duration
or number of coaching sessions.
Team facilitation: Coaching in its role as facilitator is particularly valuable during the
budget and strategy planning season. And coaching a team before a presentation can
dramatically improve performance as well as self confidence.
Work shadowing: As well as being a means of identifying an individual's behaviour and
performance, work shadowing is an excellent method of getting immediate feedback on
behaviour, with a discussion of alternative ways of handling future such situations.