LFT( LIVER FUNCTION TEST)
Laboratory Conventio Conversio Presence Measures Increase Decrease
test nal units n factor value value
reasons reasons
AST 0–35 0.01667 Large amounts in Measures Liver Usually
(Aspartate units/L or heart and liver; liver cell damage, not
Aminotransf 0–0.58 moderate damage and heart significa
erase) μkat/L amounts inis also found disease, nt
muscle, kidney, in muscles muscle
and pancreas. ↑ disorders
with MI and liver
injury. Less liver
specific than ALT
ALT 0–35 0.01667 From heart, liver, Measures Liver Usually
(Alanine units/L or muscle, kidney, liver cell damage not
Transaminas 0–0.58 pancreas. ↑ damage. (hepatitis significa
e) μkat/L negligible unless , fatty nt
parenchymal liver,
liver disease. cirrhosis)
More liver , alcohol,
specific than AST drugs,
muscle
injury
ALP 30–120 0.01667 Large amounts in Measures Bile duct Malnutrit
(Alkaline units/L or bile ducts, liver and obstructi ion, zinc
Phosphatase 0.5–2.0 placenta, bone. ↑ bone cell on, bone deficienc
) μkat/L in bile duct damage disease, y
obstruction, pregnanc
obstructive liver y
disease, rapid
bone growth
(e.g., Paget
disease),
pregnancy
GGT 0–70 0.01667 Sensitive test Measures Alcohol Usually
(Gamma- units/L or reflecting liver cell consumpt not
Glutamyl 0–1.17 hepatocellular damage and ion, liver significa
Transferase) μkat/L injury; not is also found disease, nt
helpful in in bile ducts. bile duct
differentiating issues
liver disorders.
Usually high in
chronic
alcoholics
Bilirubin– 0.1–1 17.1 Breakdown Measures Liver Anemia,
total mg/dL or product of liver's ability disease, certain
1.7–17.1 hemoglobin, to remove hemolysi medicati
μmol/L bound to bilirubin s (RBC ons
albumin, from the breakdo
conjugated in blood. wn), bile
LFT( LIVER FUNCTION TEST)
liver. duct
obstructi
on
Bilirubin– 0–0.2 17.1 Total bilirubin Bile duct Rarely
direct mg/dL or includes direct obstructi significa
0–3.4 (conjugated) and on, liver nt
μmol/L indirect bilirubin. dysfuncti
↑ with hemolysis, on
cholestasis, liver
injury.
Albumin 3.5-5.5 Measures Dehydrat Liver
g/dL liver's ability ion disease,
to produce kidney
albumin, a disease,
protein that malnutrit
helps keep ion
fluid in blood
vessels.