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References: Table 1: Association of DMFT Between GERD and Non GERD Patients

The study investigates the association between gastroesophageal reflux disease (GERD) and dental caries, revealing that GERD patients exhibit higher rates of dental caries and tooth loss compared to non-GERD patients. It also finds a significant correlation between higher body mass index (BMI) and the prevalence of GERD, while gender does not significantly affect GERD incidence. Limitations of the study include reliance on self-reported data and lack of comprehensive factors affecting dental health, suggesting the need for further research with longitudinal methods.

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0% found this document useful (0 votes)
9 views1 page

References: Table 1: Association of DMFT Between GERD and Non GERD Patients

The study investigates the association between gastroesophageal reflux disease (GERD) and dental caries, revealing that GERD patients exhibit higher rates of dental caries and tooth loss compared to non-GERD patients. It also finds a significant correlation between higher body mass index (BMI) and the prevalence of GERD, while gender does not significantly affect GERD incidence. Limitations of the study include reliance on self-reported data and lack of comprehensive factors affecting dental health, suggesting the need for further research with longitudinal methods.

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odonto logia
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Suganya, et al.

: Association of GERD and dental caries

Table 1: Association of DMFT between GERD and Conflicts of interest


non‑GERD patients There are no conflicts of interest.
Variables Mean Std. Deviation F P
Decayed teeth References
Cases 2.10 0.849 142.424 <0.001* 1. Yamasaki T, Hemond C, Eisa M, Ganocy S, Fass R. The
Controls 0.93 0.983 changing epidemiology of gastroesophageal reflux disease:
Missing teeth Are patients getting younger? J Neurogastroenterol Motil
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Cases 0.24 0.428 34.167 <0.001*
2. Gaddam S, Sharma P. Shedding light on the epidemiology
Controls 0.03 0.182
ofgastroesophageal reflux disease in India—A big step forward.
Filled teeth Indian J Gastroenterol 2011;30:105‑7.
Cases 0.34 0.756 0.805 <0.370 3. Mahajan R, Kulkarni R, Stoopler ET. Gastroesophageal reflux
Controls 0.41 0.671 disease and oral health: A narrative review. Spec Care Dent
DMFT 2022 Nov; 42:555‑64.
Cases 2.6800 1.29562 98.952 <0.001* 4. Suganya P, Rajmohan M, Prabu D, Dhamodhar D,
Controls 1.3714 1.16179 Bharathwaj VV, Sindhu R, Prashanthy MR. Investigating the
severity of dentin hypersentivity among patients aged 18‑35 years
Significance <0.001*
withgastro‑ esophageal reflux disease (GERD): A cross sectional
study. Int J Health Sci 2022;6:8903‑14.
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gastroesophageal reflux and oral lesions: A mendelian
and non‑GERD patients
randomization study. Front Genet 2022;13:1046989. doi:
Variables GERD group (n) Non‑GERD group (n) P 10.3389/fgene. 2022.1046989.
BMI 6. Mahboobi Z, Jalili asl A, Sharififard N, Faramarzi E,
Normal 67 127 <0.001* Ghavamlaleh Y. Association between gastroesophageal
Overweight 72 42 reflux disease and dental caries among adults in the Azar
Obese 36 6 cohort population: A cross‑sectional study. PLoS One
Sex 2023;18:e0289802. doi: 10.1371/journal.pone. 0289802.
Male 49 60 0.124 7. Yoshikawa H, Furuta K, Ueno M, Egawa M, Yoshino A,
Female 126 115 Kondo S, et al. Oral symptoms including dental erosion in
Significance <0.001* gastroesophageal reflux disease are associated with decreased
salivary flow volume and swallowing function. J Gastroenterol
2012;47:412‑20.
This study provides valuable insights but has limitations. 8. Chi AC, Neville BW, Krayer JW, Gonsalves WC. Oral
As a cross‑sectional study, it shows associations manifestations of systemic disease. Am Fam Physician
rather than causation. The reliance on self‑reported 2010;82:1381‑8.
GERD data and lack of assessment of disease duration 9. Sazanskaya LS, Gulua MM, Gilmiyarov EM, Margaryan EG.
The dental status of patients with gastroesophageal reflux
may affect accuracy. Additionally, factors like diet, disease depending on the intake of proton pump inhibitors.
genetics, and access to dental care were not considered. Stomatologiia (Mosk) 2020;99:25‑31.
Future research should use longitudinal methods and 10. Borysenko A, Timokhina T, Kononova O. Combined caries and
comprehensive data collection to better understand gastroesophageal reflux disease. Georgian Med News 2021:22‑7.
GERD’s impact on dental health. 11. Moynihan PJ, Kelly SA. Effect on caries of restricting sugars
intake: Systematic review to inform WHO guidelines. J Dent Res
Conclusion 2014;93:8‑18.
12. Barrington G, Khan S, Kent K, Brennan DS, Crocombe LA,
Our study found that GERD patients are more susceptible to Bettiol S. Obesity, dietary sugar and dental caries in Australian
dental caries and tooth loss, as evidenced by higher DMFT adults. Int Dent J 2019;69:383‑91.
scores. Additionally, there is a significant association between 13. Robino A, Bevilacqua L, Pirastu N, Situlin R, Di Lenarda R,
higher BMI and the prevalence of GERD, underscoring the Gasparini P, et al. Polymorphisms in sweet taste genes (TAS1R2
importance of weight management in preventing GERD. and GLUT2), sweet liking, and dental caries prevalence in an
adult Italian population. Genes Nutr 2015;10:1‑9. doi: 10.1007/
However, gender did not show a significant relationship
s12263‑015‑0485‑z.
with GERD incidence. These findings highlight the need for 14. Cagnani A, Barros AMdS, Sousa LLAd, Oliveira AMG, Zanin L,
comprehensive dental and medical care for GERD patients, Florio FM. Association between preference for sweet foods and
with a focus on monitoring and managing BMI to improve dental caries. Rev Gaucha Odontol 2014;62:25‑9.
overall health outcomes. 15. Voelker MA, Simmer‑Beck M, Cole M, Keeven E, Tira D.
Preliminary findings on the correlation of saliva pH, buffering
Financial support and sponsorship capacity, flow, consistency and streptococcus mutans in relation
Nil. to cigarette smoking. J Dent Hyg 2013;87:30‑7.

Journal of Pharmacy and Bioallied Sciences ¦ Volume 16 ¦ Supplement 4 ¦ December 2024 S3417

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