Durapore

Family
Guide

The life science business

of Merck operates as
MilliporeSigma in the
U.S. and Canada.
 Durapore® Family Guide
Overview Overview
Selection & Applications Guide
Formats
Choosing the right membrane filter is critical to the success of your process. A trusted OptiScale® Capsules
name in the industry, Durapore® polyvinylidene fluoride (PVDF) membranes are
Cartridge Filters
available in multiple pore sizes and formats to meet the needs of different operations
Cartridges
in bioprocessing including liquid sterile filtration, sterile tank and gas venting, pre-use
in-line integrity testing and final sterilizing filtration. Optiseal® Cartridges
Millidisk® Cartridges
Filters containing Durapore membranes are low protein binding and non-fiber
®

releasing with broad chemical compatibility and low extractables. They can be used Capsule Filters
in a wide range of applications including filtration of cell culture media and feeds, Opticap® XL and XLT Capsules
monoclonal antibodies (mAbs), vaccine, plasma and viral vector intermediates, and for
different operations in ophthalmics and large and small volume parenteral production. Filters for Final Filtration
All Durapore® sterilizing filters are 100% integrity tested during manufacturing. Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Our Durapore® Membrane Family
Durapore® 0.1 μm & 0.22 μm
Durapore® 0.1 μm and Durapore® 0.45 μm Durapore® 5.0 μm Durapore® 0.45 μm
0.22 μm Membrane Membrane Membrane Durapore® 5.0 μm
Sterilizing-grade membranes Bioburden reduction and partic- Membranes for aggregate and Multimedia Durapore®
for cell culture media, buffers, ulate removal filters. Durapore® particulate removal in sterile bulk
intermediate and final filtration. 0.45 μm membranes are avail- applications. Charged Durapore® 0.22 μm
able with or without an integrated Multilayer Durapore®
0.5 μm Milligard® prefilter.
Durapore® CBR 0.1 μm &
Multimedia Durapore ® Multilayer Durapore® 0.2 μm
Membrane Membrane Hydrophobic Durapore®
Sterilizing-grade membrane with Charged Durapore 0.22 μm
®
Sterilizing-grade double layer 0.22 μm
integrated Milligard® prefilter Membrane membranes (0.45/0.22 µm) for Hydrophobic-hydrophilic
media for difficult-to-filter streams. Charged sterilizing-grade difficult-to-filter streams. Durapore® 0.22 μm
membranes for endotoxin
removal and low preservative
Contact Information
adsorption. Hydrophobic-hydrophilic
Durapore® CBR 0.1 μm and
0.2 μm Membrane Durapore® 0.22 μm
Membrane
Bioburden reduction membranes
for non-critical applications. Hydrophobic Durapore® Barrier membranes containing
0.22 μm Membrane both hydrophobic and hydrophilic
Sterilizing-grade membranes for membrane for pre-use integrity 2
sterile tank and gas venting. testing of sterile filtration systems.
 Durapore® Family Guide

Selection & Overview

Applications Guide
Selection & Applications Guide
Formats
OptiScale® Capsules
Cartridge Filters
Cartridges
We offer a full portfolio of membrane filters to meet the needs of different bioprocess applications. The table below
provides a high-level overview of key applications and our preferred filtration solutions as a starting point for Optiseal® Cartridges
development or optimization. Millidisk® Cartridges

Capsule Filters

Final Filtration
Intermediates

Lipid Removal
Media/Serum
mAb Process

Viral Vectors

Ophthalmics

Cell Culture
Opticap® XL and XLT Capsules

Vaccines &

Colloids
Plasma

Buffers
SVPs

LVPs
Filters for Final Filtration

Gas
Millipak® Final Fill Capsules
Particle Removal and Sterile Filter Protection
Milligard® PES Filters ˜ ˜ ˜ ˜ ˜ ˜ ˜ ˜ ˜ M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Milligard® Filters ˜ ˜ ˜ ˜ ˜ ˜
Polysep™ II Filters ˜ ˜ ˜ ˜ ˜ ˜
Durapore® 0.1 μm & 0.22 μm
Lifegard™ Filters ˜ ˜ ˜ ˜
Bioburden Reduction
Durapore® 0.45 μm
Milligard® PES Filters ˜ ˜ ˜ ˜ ˜ ˜ Durapore® 5.0 μm
Durapore® 0.45 Filters ˜ ˜ ˜ ˜ ˜ ˜ Multimedia Durapore®
Sterile Filtration Charged Durapore® 0.22 μm
Millipore Express SHC Filters
®
˜ ˜ ˜ ˜ ˜ ˜ ˜ ˜ ˜ Multilayer Durapore®
Millipore Express® SHF Filters ˜ ˜ ˜ ˜ ˜
Durapore® CBR 0.1 μm &
Millipore Express® PHF Filters ˜ ˜ ˜ ˜ 0.2 μm
Durapore® 0.22 μm Filters ˜ ˜ ˜ ˜ ˜ ˜ ˜ ˜ ˜ Hydrophobic Durapore®
Durapore Multilayer Filters
®
˜ ˜ ˜ 0.22 μm
Aervent® Filters ˜ Hydrophobic-hydrophilic
Aerex® Filters ˜ Durapore® 0.22 μm
Millipore Express® SPG Filters ˜
Mycoplasma Removal and Sterile Filtration Contact Information
Millipore Express® SHR Filters ˜
Durapore® 0.1 μm Filters ˜
Viresolve® Barrier Filters ˜

3
The Emprove Program ® Durapore® Family Guide

Overview

Your fast track through regulatory challenges Selection & Applications Guide
Formats
Complementing our product portfolio, the OptiScale® Capsules
Emprove® Program provides three types
Cartridge Filters
of dossiers to support different stages of
Cartridges
development and manufacturing operations
such as qualification, risk assessment and Optiseal® Cartridges
process optimization. The dossiers consolidate Millidisk® Cartridges
comprehensive product-specific testing data,
quality statements and regulatory information Capsule Filters
in a readily-available format to simplify your Opticap® XL and XLT Capsules
compliance needs.
Filters for Final Filtration
Millipak® Final Fill Capsules
For more information, please visit:
M
 illidisk® Barrier Cartridges
MerckMillipore.com/Emprove and Millipak® Barrier Capsules

or SigmaAldrich.com/Emprove
Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
Durapore® 5.0 μm

Mobius Single-Use Solutions

® Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
Durapore® filters are part of the Mobius®
0.2 μm
component library.
Hydrophobic Durapore®
Whether you are looking to introduce single-use 0.22 μm
manufacturing components into your current Hydrophobic-hydrophilic
process or investigating how you can implement Durapore® 0.22 μm
a single-use process train, Mobius® products and
solutions help meet your evolving process needs. Contact Information

For more information, please visit:

MerckMillipore.com/singleuse-myway

4
 Durapore® Family Guide
Formats Overview
Selection & Applications Guide

Multiple formats offer flexibility and scalable solutions for both single-use and stainless steel operations. Formats
OptiScale® Capsules
Cartridge Filters

CBR 0.1 μm/

Hydrophobic

Hydrophobic
Hydrophilic
Multimedia
Durapore®

Durapore®

Durapore®

Durapore®

Durapore®

Durapore®

Durapore®

Durapore®

Durapore®
Multilayer
0.45/0.22
Cartridges

0.1 μm &

Charged
0.22 μm

0.22 μm

0.45 μm

0.22 μm

0.22 μm

0.22 μm
Format

5.0 μm
Optiseal® Cartridges
Size

μm
Millidisk® Cartridges
Single-use Capsule Filters (small to large scale)
OptiScale® Capsules 25, 47 A A A A
Capsule Filters
Opticap® XL Capsules 2 A A
Opticap® XL and XLT Capsules
4 G, S, A A
5 A A A
Filters for Final Filtration
10 G, S, A G, S, A A G, S, A A
Millipak® Final Fill Capsules
Opticap® XLT Capsules 10, 20, 30 G, S, A G, S, A G, S
Cartridge Filters for Stainless Steel Operations (small to large scale)
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Millidisk® Cartridges 10, 20, A A A
30, 40
Optiseal® Cartridges 4 A A Durapore® 0.1 μm & 0.22 μm
Cartridges 5 A A Durapore® 0.45 μm
10, 20, 30 A A A A A A A
Durapore® 5.0 μm
40 A A
Multimedia Durapore®
Filters for Final Filtration
Charged Durapore® 0.22 μm
Millipak® Barrier Capsule 200 A
Multilayer Durapore®
Millidisk® Barrier Cartridge 40 A
Millipak® Final Fill Capsules 20 G, S G, S G, S Durapore® CBR 0.1 μm &
0.2 μm
40 G, S G, S
60 G, S G, S G, S G, S
Hydrophobic Durapore®
0.22 μm
100 G ,S G, S
Hydrophobic-hydrophilic
200 G, S G, S G, S G, S
Durapore® 0.22 μm
G = GAMMA-COMPATIBLE (CAPSULES): Product is gamma-compatible and can be autoclaved
A = AUTOCLAVABLE: Product can be autoclaved
S = STERILE (CAPSULES): Product has been pre-sterilized by gamma irradiation
Contact Information
Regulatory Compliance
Filters with Durapore® membranes are designed, developed, and manufactured in accordance with a Quality Management System approved by an accredited registering body to an
ISO® 9001 Quality Systems Standard. Each Durapore® filter is shipped with a Certificate of Quality.
Each cartridge filter, Millipak® Final Fill, Opticap® XL and Opticap® XLT capsule filter is integrity tested during manufacturing and is supported with an Emprove® Material
Qualification Dossier or Validation Guide for compliance with regulatory requirements. For traceability and easy identification, each device is marked with the product name and
identifying characteristics.

Emprove® Program
Complementing our product portfolio, the Emprove® Program provides three types of dossiers to support different stages of development and manufacturing operations such as
5
qualification, risk assessment and process optimization. The dossiers consolidate comprehensive productspecific testing data, quality statements and regulatory information in a
readily-available format to simplify your compliance needs.
OptiScale Capsules ® Durapore® Family Guide

For Screening and Scaling Overview

Selection & Applications Guide
Our OptiScale® disposable capsule filters provide a convenient small-volume
option for process development screening and scaling. They are ideal for quickly Formats
evaluating performance of different filters with various process streams. OptiScale® Capsules
Cartridge Filters
Cartridges
Optiseal® Cartridges
OptiScale® Capsules Millidisk® Cartridges

Cartridge Filters Capsule Filters

Opticap® XL and XLT Capsules
For Pilot and Production Scale Processing
Filters for Final Filtration
Cartridge Filters
Millipak® Final Fill Capsules
Our cartridge filters are designed for pilot and production scale processing in M
 illidisk® Barrier Cartridges
stainless steel housings. These filters provide minimal differential pressure with and Millipak® Barrier Capsules
high flow rates and throughput and are designed to withstand multiple steam-
in-place cycles. A full range of filtration areas and connection options are
available for maximum flexibility. Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
Cartridge Filters
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Optiseal™ Cartridge Filters
Multilayer Durapore®
Optiseal® cartridge filters are designed for small-volume processing and
feature a robust cartridge-to-housing sealing mechanism for use in stainless Durapore® CBR 0.1 μm &
steel housings under rigorous processing conditions. The cartridges contain 0.2 μm
membrane in a pleated configuration, resulting in efficient and economical Hydrophobic Durapore®
particle removal while providing high flow rates and throughput. 0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm
Optiseal® Cartridge Filters

Contact Information

Millidisk® Cartridge Filters

Millidisk® Cartridge filters are designed for small-volume processing in stainless
steel housings. These filters contain Durapore® membrane in a stacked disc
format to minimize hold-up volume.
6
Millidisk® Cartridge Filters
Capsule Filters Durapore® Family Guide

For Pilot and Production Scale Processing Overview

Selection & Applications Guide
Formats
OptiScale® Capsules
Opticap® XL and XLT Capsules
Cartridge Filters
Opticap® XL single-use capsule filters are designed for pilot and production Cartridges
scale processing, are available with a range of inlet/outlet connections and
are offered in autoclavable, sterile and gamma-compatible formats. Optiseal® Cartridges
Millidisk® Cartridges
These capsules minimize cleaning, assembly and validation requirements
which translates to increased flexibility, more rapid turnaround and less
downtime than maintaining stainless steel operations. Capsule Filters
Opticap® XLT single-use capsule filters are available with or without a Opticap® XL and XLT Capsules
pressure gauge port. The T-line design accommodates series or parallel
filtration, and a specially-designed stand enables quick and easy integration Opticap® XL Capsules Opticap® XLT Capsules Filters for Final Filtration
into your existing operations.
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

7
Millipak Final Fill Capsules
® Durapore® Family Guide

Overview
Selection & Applications Guide
For Maximum Product Yield in High Value, Small-Volume Processing Formats
Millipak® Final Fill capsule filters are designed for reliable filtration of OptiScale® Capsules
small-volume, high value solutions. In final filling, it is critical to maximize
Cartridge Filters
product recovery and maintain sterility. The filter's stacked disc design
minimizes hold-up volume over standard pleated devices, increasing Cartridges
product recovery. Optiseal® Cartridges
These user-friendly filters feature a multi-purpose port that simplifies Millidisk® Cartridges
venting, integrity testing and sampling, and is validated to maintain an
aseptic flow path even after multiple actuations.
Capsule Filters
Millipak® Final Fill filters contain the proven and trusted Durapore® Opticap® XL and XLT Capsules
membrane in multiple pore sizes offering flexibility for your specific
process needs.
Filters for Final Filtration
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
Benefits Membrane Pore Sizes and Millipak® Barrier Capsules
• Maximizes product recovery in final and high Available with particulate removal, bioburden
value filtration reduction and sterilizing-grade Durapore® Durapore® 0.1 μm & 0.22 μm
polyvinylidene fluoride (PVDF) membranes for
• Simplifies operation and reduces risk of microbial Durapore® 0.45 μm
both liquid and solvent applications.
and particulate contamination
Durapore® 5.0 μm
• Hydrophilic Durapore® membrane: 0.1 µm,
• Contains Durapore® membrane for high flow Multimedia Durapore®
0.22 µm, 0.45 µm, 5.0 µm
rates, low binding and extractables, and broad
chemical compatibility • Hydrophobic Durapore® membrane: 0.22 µm Charged Durapore® 0.22 μm
Multilayer Durapore®
• Improves integration into single-use assemblies
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
Millipak Final Fill Filters Design Features
® 0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm
Vent, sample, and integrity test while Monitor wetting and filtration operations
preventing contamination with the through the transparent housing
Aseptic Multi-Purpose Port (AMPP)
Contact Information

Single-use assembly integration is Minimize hold-up volume with the

simplified with a hook stacked disc design

Enhanced digital integration with the Proven performance with time-tested

2-D barcode Durapore® membrane
8
Millipak® Final Fill Capsules Durapore® Family Guide

Maximize Product Recovery Hold-Up Volumes of Market Leading Filters Overview

In applications like final filtration where maximizing Millipak® Final Fill filters PES pleated filters PVDF pleated filters
Selection & Applications Guide
product recovery is critical, the low hold-up volume of 40 Formats
Millipak® Final Fill filters translates to more vials filled, as OptiScale® Capsules
compared to traditional pleated filters. Millipak® Final Fill 30
filters incorporate Durapore® membrane bonded to solid Cartridge Filters
discs instead of the support material in pleated filters, Cartridges

Hold-up Volume (mL)

resulting in lower hold-up volume and reduced risk of 20
Optiseal® Cartridges
particulates, Figure 1. Consistent, high product recoveries
are achieved across filtration areas from 100-1000 cm2. Millidisk® Cartridges
10
Millipak® Final Fill filters maximize your product recovery,
increasing the efficiency of this critical process step, Capsule Filters
Figure 2. 0
0 200 400 600 800 1000 1200 1400 Opticap® XL and XLT Capsules
Filtration area (cm )
2

Filters for Final Filtration

Figure 2
Millipak® Final Fill Capsules
Hold-up volume of Millipak® Final Fill filters as compared to pleated
polyethersulfone (PES) or polyvinylidene fluoride (PVDF) filters of different M
 illidisk® Barrier Cartridges
areas. Values represent the mean and standard deviation from replicate tests. and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
Figure 1
0.22 μm
Membrane is bonded to solid discs instead of support material used in pleated
filters, resulting in lower hold-up volume and reduced risk of particulates. Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

9
Millipak® Final Fill Capsules Durapore® Family Guide

Robust Protection Combined with Ease Overview

of Use Selection & Applications Guide
The Aseptic Multi-Purpose Port (AMPP) has been designed Formats
for ergonomic use with gloves, and visible ‘open’ and ‘closed’ OptiScale® Capsules
locking positions, Figure 3. It contains three O-rings – the
Cartridge Filters
lower O-ring seals the flow path when the AMPP is closed,
and two upper O-rings maintain an aseptic area that prevents Cartridges
cross-contamination between the environment and flow path. Optiseal® Cartridges
This sterile boundary is maintained after heavy microbial
challenge and multiple actuations keeping your process Millidisk® Cartridges
safe from contaminant exposure. This is critical in final fill,
and also for sterility assurance in redundant filtration trains Capsule Filters
where the flow path downstream of the redundant filter Opticap® XL and XLT Capsules
must not be compromised.
Filter venting, integrity testing and sampling can all be Figure 3 Filters for Final Filtration
performed through the single AMPP, lowering the risks Aseptic Multi-Purpose Port (AMPP).
Millipak® Final Fill Capsules
associated with multiple filter connection points and
streamlining process design. M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Scalable Mobius® Single-use Solutions
Multiple filter sizes enable easy scale up and sizing. All Millipak® Final Fill filters are part of the Mobius® Durapore® 0.1 μm & 0.22 μm
Millipak® Final Fill filter capsules are available as non- library. This provides you with the flexibility to Durapore® 0.45 μm
sterilized (gamma irradiation and autoclave compatible) design single-use assemblies that meet your specific
processing requirements. Durapore® 5.0 μm
or sterilized by gamma irradiation.
Multimedia Durapore®
For more information, please visit:
MerckMillipore.com/Singleuse-MyWay Charged Durapore® 0.22 μm
Multilayer Durapore®
Size Format
20 40 60 100 200 The Emprove® Program – Your Fast Track Durapore® CBR 0.1 μm &
Durapore® (100 cm2) (200 cm2) (300 cm2) (500 cm2) (1000 cm2)
through Regulatory Challenges 0.2 μm
Membrane
Hydrophobic Durapore®
0.1 μm √ √ √ √ √ Complementing our product portfolio, the Emprove®
0.22 μm
Program provides three types of dossiers to support
0.22 μm √ √ √ √ √ different stages of development and manufacturing Hydrophobic-hydrophilic
operations such as qualification, risk assessment and Durapore® 0.22 μm
0.45 μm √ √ √ √ √ process optimization.
For more information, please visit: Contact Information
5.0 μm √ √ MerckMillipore.com/Emprove or
SigmaAldrich.com/Emprove
0.22 μm phobic √ √ √

10
Millidisk Barrier Cartridge and ® Durapore® Family Guide

Millipak Barrier Capsule Filters ®

Overview
Selection & Applications Guide
Formats
OptiScale® Capsules
For Pre-Use Post-Sterilization Integrity Testing
Cartridge Filters
Milllipak® Barrier capsules and Millidisk® Barrier cartridge filters simplify
Cartridges
in-line pre-use, post-sterilization integrity testing (PUPSIT) of single or
redundant liquid filtration systems. Optiseal® Cartridges

The filters contain separate layers of hydrophobic and hydrophilic 0.22 μm Millidisk® Cartridges
Durapore® sterilizing-grade membranes in a stacked disk design allowing the
sterile flow of liquid and gas. These permeable sterile barrier filters simplify Capsule Filters
wetting, flushing and integrity testing of upstream sterile filters in filtration Opticap® XL and XLT Capsules
assemblies while maintaining the system sterility and removing the constraint
of a flush bag or can.
Filters for Final Filtration
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Barrier Filters Flush Bag Downstream Filters Durapore® 0.1 μm & 0.22 μm
Sterile Venting
and Sampling
Sterile Venting
and Sampling Durapore® 0.45 μm
Integrity Tester/
Airline Connection
Integrity Tester/
Airline Connection
Integrity Tester/
Airline Connection Durapore® 5.0 μm
Multimedia Durapore®
Gas
Filter
Gas
Filter
Gas
Filter
Gas
Filter
Charged Durapore® 0.22 μm
Multilayer Durapore®
Inlet
Sterilizing Filter
Inlet
Sterilizing Filter
Inlet
Sterilizing Filter Durapore® CBR 0.1 μm &
Barrier Filter Flush Bag Rush Filter
0.2 μm
Hydrophobic Durapore®
0.22 μm

Barrier Filter Flush Bag Downstream Filter

Hydrophobic-hydrophilic
Durapore® 0.22 μm
Ability to Retest ✔ ✘ ✔

Ability to Dry the Contact Information

✔ ✘ ✔
Product Filter

Simple Design ✔ ✔ ✘

11
Filters Containing Durapore 0.1 μm and ® Durapore® Family Guide

0.22 μm Membrane Overview

Selection & Applications Guide
For sterile filtration of liquids Formats
OptiScale® Capsules
Cartridge Filters

Filters containing hydrophilic, Durapore® Cartridges

polyvinylidene fluoride (PVDF) membranes Optiseal® Cartridges
can be used for applications requiring Millidisk® Cartridges
the highest degree of sterility assurance.
Durapore® 0.1 μm membrane filters can Capsule Filters
be used for filtration of cell culture media Opticap® XL and XLT Capsules
and feeds.
Filters for Final Filtration
Filters containing Durapore® 0.22 μm
Millipak® Final Fill Capsules
membrane are suitable for sterile filtration
M
 illidisk® Barrier Cartridges
of liquids.
and Millipak® Barrier Capsules

Benefits Durapore® 0.1 μm & 0.22 μm

• Protects processes from microbial contamination Durapore® 0.45 μm
• Low protein binding membrane yields high protein Durapore® 5.0 μm
recovery with minimal product loss Multimedia Durapore®
• Broad chemical compatibility, low extractables Charged Durapore® 0.22 μm
• For filtration processes requiring high flow rates Multilayer Durapore®
and throughputs Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
Filter Formats
0.22 μm
• OptiScale® capsules Hydrophobic-hydrophilic
The Emprove® Program. Your fast track through
• Cartridge filters regulatory challenges. Durapore® 0.22 μm

• Optiseal® cartridges Complementing our product portfolio, the Emprove® Program

provides three types of dossiers to support different stages Contact Information
• Millidisk® cartridges of development and manufacturing operations such as
qualification, risk assessment and process optimization.
• Opticap® XL and XLT capsules
• Millipak® Final Fill capsules
For more information, please visit:

MerckMillipore.com/Emprove or
SigmaAldrich.com/Emprove 12
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Overview
Selection & Applications Guide
Performance of filters containing Durapore® 0.1 μm and 0.22 μm sterilizing-grade membrane with a panel of cell culture
media: figures show throughput over time for the panel of media. Formats
OptiScale® Capsules
The filters have different microbial retention characteristics determined by membrane pore size. Filter selection is
generally guided by retention requirements for the process step, throughput performance in the process fluid, and Cartridge Filters
compatibility of the process fluid with the filter. Cartridges
Optiseal® Cartridges
Millidisk® Cartridges

Capsule Filters
Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

13
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

OptiScale® Capsule Filter Specifications Overview

Selection & Applications Guide
Description OptiScale® 25 OptiScale® 47
Formats
Nominal Dimensions
Maximum length: 39 mm (1.52 in.) with female Luer-Lok™ inlet/male luer 82 mm (3.24 in.) with flange inlet/hose barb outlet OptiScale® Capsules
slip outlet 74 mm (2.91 in.) with flange inlet/flange outlet
94 mm (3.70 in.) with hose barb inlet/hose barb outlet Cartridge Filters
Body Diameter: 31 mm (1.21 in.) 70 mm (2.75 in.) Cartridges
Weight: 0.19 oz (5.5 g) 2.4 oz (69 g)
Optiseal® Cartridges
Filtration Area 3.5 cm2 17.7 cm2
Millidisk® Cartridges
Materials of Construction
Filter membrane: Hydrophilic PVDF Hydrophilic PVDF
Structural components: Polypropylene Polycarbonate Capsule Filters
Supports: Polypropylene Polypropylene
Vent cap: Polypropylene PVDF Opticap® XL and XLT Capsules
Internal seal rings: — Fluoroelastomers
Housing Vent Capped vent with female Luer connections on inlet side Adjustable vent with male luer and female Luer-Lok™ Filters for Final Filtration
of device. connections on inlet side of device.
Millipak® Final Fill Capsules
Maximum Inlet Pressure 4.1 bar (60 psi) at 25 °C 5.5 bar (80 psi) at 25 °C
M
 illidisk® Barrier Cartridges
Maximum Differential Pressure
Forward: 4.1 bar (60 psi) at 25 °C 5.6 bar (80 psi) at 25 °C and Millipak® Barrier Capsules
Reverse: 0 psi at 25 °C 0.7 psi at 25 °C
Oxidizable Substances — Meets the USP Oxidizable Substances Test requirements
Durapore® 0.1 μm & 0.22 μm
for sterile purified water after a water flush of 100 mL
Bacterial Endotoxin Aqueous extraction contains <0.25 EU/mL as — Durapore® 0.45 μm
determined by the Limulus Amebocyte Lysate (LAL) Durapore® 5.0 μm
Test. This meets the requirements of USP <85>.
Total Organic Carbon (TOC) / Filter effluent meets the WFI requirement of USP <643>, —
Multimedia Durapore®
Conductivity for Total Organic Carbon and USP <645> for Water Charged Durapore® 0.22 μm
Conductivity at 25 ºC after a WFI flush of 15 mL.
Sterilization May be autoclaved for 1 cycle of 60 minutes at 123 °C. May be autoclaved for 3 cycles of 60 minutes at 126 °C.
Multilayer Durapore®
Non-Fiber Releasing Durapore® membrane meets the criteria for a “non-fiber releasing” filter; defined in 21 CFR 210.3 (b) (6). Durapore® CBR 0.1 μm &
0.2 μm
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
Hydrophobic Durapore®
information provided by raw material suppliers. 0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

14
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Cartridge Filter Specifications Overview

Selection & Applications Guide
Description 5-inch per 10-inch
Formats
Nominal Dimensions
Outside diameter: 6.9 cm (2.7 in.) 6.9 cm (2.7 in.) OptiScale® Capsules
Filtration Area 0.35 m (3.7 ft )
2 2
0.69 m (7.4 ft )
2 2
Cartridge Filters
Materials of Construction Cartridges
Filter membrane: Hydrophilic PVDF
Film edge: Polypropylene Optiseal® Cartridges
Supports: Polypropylene
Structural components*: Polypropylene
Millidisk® Cartridges
Vent O-rings: Silicone
Maximum Differential Pressure Capsule Filters
Forward: 5.5 bar (80 psid) at 25 °C, 1.8 bar (25 psid) at 80 °C, 345 mbar (5 psid) at 135 °C
Opticap® XL and XLT Capsules
Reverse: 3.4 bar (50 psid) at 25 °C, intermittent
Bubble Point at 23 °C
0.1 μm: ≥ 4830 mbar (70.0 psig) air with water Filters for Final Filtration
0.22 μm: ≥ 3450 mbar (50.0 psig) air with water Millipak® Final Fill Capsules
Air Diffusion Through a water wet membrane at ambient temperature:
M
 illidisk® Barrier Cartridges
0.1 μm at 3.9 bar (56 psig): ≤ 10.0 cc/min ≤ 20.0 cc/min
0.22 μm of 2.8 bar (40 psig): ≤ 6.6 cc/min ≤ 13.3 cc/min
and Millipak® Barrier Capsules
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This
meets the requirements of USP <85>.
Durapore® 0.1 μm & 0.22 μm
Bacterial Retention Quantitative retention of 107 CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM© F838 methodology.
Durapore® 0.45 μm
Sterilization Autoclave: 126 °C, 60 minutes, up to 5 times
Steam-in-place: 135 °C, 60 minutes, up to 30 times
Durapore® 5.0 μm
Non-Fiber Releasing Durapore® membrane meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6). Multimedia Durapore®
Toxicity Component materials meet the requirements of USP <88> Biological Reactivity Tests for Class VI Plastics. Charged Durapore® 0.22 μm
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on Multilayer Durapore®
information provided by raw material suppliers.
Durapore® CBR 0.1 μm &
Total Organic Carbon (TOC) / Autoclaved filter effluent meets the WFI requirement of USP <643>, for Total Organic Carbon and USP <645>
0.2 μm
Conductivity for Water Conductivity at 25 ºC after a WFI flush of:
0.1 μm: 3.5 L per 10-inch cartridge Hydrophobic Durapore®
0.22 μm: 5.5 L per 10-inch cartridge
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

15
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Optiseal® Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Optiseal®
Formats
Materials of Construction
Filter membrane: Hydrophilic Durapore® PVDF OptiScale® Capsules
Structural components: Polypropylene
O-rings: Silicone Cartridge Filters
Connections Optiseal® cartridges incorporate a unique double 2-123 (silicone) O-ring seal and are used with Optiseal® Cartridges
stainless steel housings.
Optiseal® Cartridges
Pore Sizes 0.1 μm or 0.22 μm
Millidisk® Cartridges
Filtration Area 0.18 m2 (1.9 ft2)
Maximum Differential Pressure
Forward: 5.5 bar (80 psid) at 25 °C, 3.5 bar (50 psid) at 80 °C, 0.35 bar (5 psid) at 135 °C
Capsule Filters
Reverse: 3.5 bar (50 psid) at 25 °C Opticap® XL and XLT Capsules
Gravimetric Extractables The extractables level was equal to or less than 10 mg per cartridge after 24 hours in ASTM® Type 1 reagent-
grade water at controlled room temperature
Filters for Final Filtration
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for sterile purified water after a water flush of 500 mL.
Millipak® Final Fill Capsules
Bacterial Endotoxin The cartridge meets the definition of a sterilizing-grade filter as described in the FDA “Guideline of Sterile Drug
Products Produced by Aseptic Processing” (June 1987). M
 illidisk® Barrier Cartridges
Bacterial Retention Quantitative retention of 107 CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM© F838 methodology. and Millipak® Barrier Capsules
Toxicity Component materials meet the requirements of the USP <88> Biological Reactivity tests for Class VI plastics.
Integrity Test Durapore® 0.1 μm & 0.22 μm
0.1 μm Bubble point: > 4830 mbar (70.0 psi) at 25 ºC.
Air Diffusion: < 7 cc/min per cartridge at 3.9 bar (56.0 psi) through a 25 °C water wet membrane. Durapore® 0.45 μm
0.22 μm Bubble point: > 3450 mbar (50.0 psi) at 25 ºC. Durapore® 5.0 μm
Air Diffusion: < 5 cc/min per cartridge at 2.8 bar (40.0 psi) through a 25 °C water wet membrane.
Multimedia Durapore®
Multiple Steaming Cartridges maintain integrity (per bacterial retention testing) after 30 steam cycles of 30 minutes at 135 °C.
Continuous Steaming Cartridges maintain integrity after 100 hours of continuous steaming at 135 °C. Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

16
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Millidisk® Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Millidisk® 10 Millidisk® 20 Millidisk® 30 Millidisk® 40
Formats
Filtration Area 500 cm2 (0.54 ft2) 1000 cm2 (1.08 ft2) 1500 cm2 (1.61 ft2) 2000 cm2 (2.15 ft2)
Materials of Construction OptiScale® Capsules
Filter membrane: Durapore® PVDF membrane Cartridge Filters
Structural components: Polysulfone
O-rings: Silicone Cartridges
Maximum Differential Pressure Optiseal® Cartridges
Forward: 4.1 bar (60 psid) at 25 °C, 1.7 bar (25 psid) at 80 °C, 345 mbar (5 psid) at 123 °C
Reverse: 690 mbar (10 psid) at 25 °C
Millidisk® Cartridges
Bubble Point at 23 °C
0.1 μm: ≥ 4830 mbar (70.0 psig) in water* Capsule Filters
0.22 μm: ≥ 3450 mbar (50.0 psig) in water
Opticap® XL and XLT Capsules
Connections Millidisk filters incorporate a double 2-118 (silicone) O-ring seal and are used with Millidisk or Millidisk /
® ® ®

Milligard® stainless steel housings.

Filters for Final Filtration
Gravimetric Extractables Maximum values post autoclaving and a 24 hour soak in ASTM® Type 1 reagent grade water for hydrophilic
units and in 70/30 IPA/Water solution for hydrophobic units: Millipak® Final Fill Capsules
2.5 mg/unit 5 mg/unit 7.5 mg/unit 10 mg/unit
M
 illidisk® Barrier Cartridges
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for sterile purified water after steaming and a water
and Millipak® Barrier Capsules
flush of 200 mL.
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL per 10-inch filter as determined by the Limulus Amebocyte Lysate (LAL)
test. This meets the requirements of USP <85>. Durapore® 0.1 μm & 0.22 μm
Bacterial Retention Quantitative retention of 10 CFU/cm² Brevundimonas diminuta ATCC 19146 per ASTM© F838 methodology.
7 ®
Durapore® 0.45 μm
Sterilization Autoclave: 126 °C, 60 minutes, up to 5 times
Steam-in-place: 135 °C, 60 minutes, up to 5 times Durapore® 5.0 μm
Toxicity Component materials meet the requirements of USP <88> Biological Reactivity Tests for Class VI Plastics. Multimedia Durapore®
*Transient pressure excursion above the maximum differential and inlet pressures of the unit for integrity testing is acceptable. Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

17
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Opticap® XL and XLT Autoclavable Capsule Filter Specifications Overview

Selection & Applications Guide
Opticap® Opticap® Opticap® Opticap® Opticap® Opticap® Opticap®
Description XL 2 XL 4 XL 5 XL 10 XLT 10 XLT 20 XLT 30 Formats
Nominal Dimensions OptiScale® Capsules
Maximum length: 14.2 cm 19.6 cm 21.6 cm 33.5 cm 38.1 cm 62.5 cm 87.1 cm
(5.6 in.) (7.7 in.) (8.5 in.) (13.2 in.) (15 in.) (24.6 in.) (34.3 in.) Cartridge Filters
Body diameter: 8.4 cm 8.4 cm 10.7 cm 10.7 cm — — — Cartridges
(3.3 in.) (3.3 in.) (4.2 in.) (4.2 in.)
Fitting to Fitting
Optiseal® Cartridges
Sanitary flange to sanitary flange: — — — — 15.2 cm 15.2 cm 15.2 cm Millidisk® Cartridges
(6.0 in.) (6.0 in.) (6.0 in.)
Sanitary flange to hose barb: — — — — 17.5 cm 17.5 cm 17.5 cm
(6.9 in.) (6.9 in.) (6.9 in.) Capsule Filters
Hose barb to hose barb: — — — — 19.8 cm 19.8 cm 19.8 cm
(7.8 in.) (7.8 in.) (7.8 in.) Opticap® XL and XLT Capsules
Filtration Area 0.09 m² 0.19 m² 0.35 m² 0.69 m² 0.69 m² 1.4 m² 2.1 m²
(0.93 ft²) (2.09 ft²) (3.7 ft²) (7.4 ft²) (7.4 ft²) (14.8 ft²) (22.2 ft²) Filters for Final Filtration
Materials of Construction Millipak® Final Fill Capsules
Filter membrane: Hydrophilic PVDF
Film edge: Polypropylene M
 illidisk® Barrier Cartridges
Supports: Polypropylene and Millipak® Barrier Capsules
Structural components*: Polypropylene
Vent O-rings: Silicone
Vent/Drain /4 in. hose barb with double O-ring seal; connects to 1/8 in. tubing
1 Durapore® 0.1 μm & 0.22 μm
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C Durapore® 0.45 μm
2.8 bar (40 psi) at 60 °C
1.0 bar (15 psi) at 80 °C Durapore® 5.0 μm
Maximum Differential Pressure Multimedia Durapore®
Forward: 5.5 bar (80 psid) at 25 °C, 1.0 bar (15 psid) at 80 °C 5.5 bar (80 psid) at 25 °C, 1.7 bar (25 psid)
at 80 °C
Charged Durapore® 0.22 μm
Reverse: 3.4 bar (50 psid) at 25 °C, intermittent 3.4 bar (50 psid) at 25 °C Multilayer Durapore®
Bubble Point at 23 °C Durapore® CBR 0.1 μm &
0.1 μm: ≥ 4830 mbar (70.0 psig) air with water
0.2 μm
0.22 μm: ≥ 3450 mbar (50.0 psig) air with water
Air Diffusion Through a water wet membrane at ambient temperature: Hydrophobic Durapore®
0.1 μm at 3.9 bar (56 psig): — ≤ 7.5 cc/min ≤ 10.0 cc/min ≤ 20.0 cc/min ≤ 20.0 cc/min ≤ 40.0 cc/min ≤ 60.0 cc/min 0.22 μm
0.22 μm at 2.8 bar (40 psig): — ≤ 5.5 cc/min ≤ 6.6 cc/min ≤ 13.3 cc/min ≤ 13.3 cc/min ≤ 26.6 cc/min ≤ 39.9 cc/min Hydrophobic-hydrophilic
NVR Gravimetric Extractables After autoclaving and a 24-hour soak in ASTM® Type 1 reagent grade water at controlled room temperature: Durapore® 0.22 μm
≤ 10 mg ≤ 10 mg ≤ 15 mg ≤ 25 mg ≤ 25 mg ≤ 50 mg ≤ 75 mg
Oxidizable Substances Meets the requirements of the USP Oxidizable Substances Test requirements for sterile purified water after a
water flush of: Contact Information
500 mL 500 mL 500 mL 1000 mL 1000 mL 2000 mL 3000 mL
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This
meets the requirements of USP <85>.
Bacterial Retention Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology.
Sterilization May be autoclaved for 3 cycles of 60 minutes at 126 °C. Cannot be steam sterilized in-line.

18
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Opticap® XL and XLT Autoclavable Capsule Filter Specifications Overview

Selection & Applications Guide
Opticap® Opticap® Opticap® Opticap® Opticap® Opticap® Opticap®
Description XL 2 XL 4 XL 5 XL 10 XLT 10 XLT 20 XLT 30 Formats
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6). OptiScale® Capsules
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. Cartridge Filters
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers.
Cartridges

*Cage, core, end caps, and capsule housing

Optiseal® Cartridges
Millidisk® Cartridges
Opticap® XL and XLT Sterile and Gamma-Compatible Capsule Filter Specifications
Capsule Filters
Opticap® Opticap® Opticap® Opticap® Opticap®
Description XL 4 XL 10 XLT 10 XLT 20 XLT 30
Opticap® XL and XLT Capsules
Nominal Dimensions
Maximum length: 19.6 cm (7.7 in.) 33.5 cm (13.2 in.) 38.1 cm (15 in.) 62.5 cm (24.6 in.) 87.1 cm (34.3 in.) Filters for Final Filtration
Body diameter: 8.4 cm (3.3 in.) — — — —
Millipak® Final Fill Capsules
Fitting to Fitting
Sanitary flange to sanitary flange: — — 15.2 cm (6.0 in.) 15.2 cm (6.0 in.) 15.2 cm (6.0 in.)
M
 illidisk® Barrier Cartridges
Sanitary flange to hose barb: — — 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) and Millipak® Barrier Capsules
Hose barb to hose barb: — — 19.8 cm (7.8 in.) 19.8 cm (7.8 in.) 19.8 cm (7.8 in.)
Filtration Area 0.18 m2 (1.9 ft²) 0.73 m2 (7.8 ft²) 0.73 m2 (7.8 ft²) 1.45 m2 (15.6 ft²) 2.17 m2 (23.4 ft²)
Durapore® 0.1 μm & 0.22 μm
Materials of Construction
Filter membrane: Hydrophilic PVDF Durapore® 0.45 μm
Film edge: Polyethylene Durapore® 5.0 μm
Supports: Polyester/polyethylene
Structural components*: Gamma-stable polypropylene Multimedia Durapore®
Vent O-rings: Silicone
Charged Durapore® 0.22 μm
Vent/Drain /4 in. hose barb with double O-ring seal; connects to 1/8 in. tubing
1
Multilayer Durapore®
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C
Durapore® CBR 0.1 μm &
2.8 bar (40 psi) at 60 °C
0.2 μm
1.0 bar (15 psi) at 80 °C
Maximum Differential Pressure
Hydrophobic Durapore®
Forward: 5.5 bar (80 psid) at 25 °C 5.5 bar (80 psid) at 25 °C 0.22 μm
1.0 bar (15 psid) at 80 °C 1.7 bar (25 psid) at 80 °C Hydrophobic-hydrophilic
Reverse: 3.5 bar (50 psid) at 25 °C 3.5 bar (50 psid) at 25 °C Durapore® 0.22 μm
Bubble Point at 23 °C
0.1 μm: ≥ 4830 mbar (70.0 psig) air with water
0.22 μm: ≥ 3450 mbar (50.0 psig) air with water Contact Information
Air Diffusion Through a water wet membrane at ambient temperature:
0.1 μm at 3.9 bar (56 psig): ≤ 5.7 cc/min ≤ 21.1 cc/min ≤ 21.1 cc/min ≤ 42.2 cc/min ≤ 63.3 cc/min
0.22 μm at 2.8 bar (40 psig): ≤ 4.6 cc/min ≤ 14.0 cc/min ≤ 14.0 cc/min ≤ 28.0 cc/min ≤ 42.0 cc/min
Oxidizable Substances Meets the requirements of the USP Oxidizable Substances Test after a water flush of:
1000 mL 1000 mL 1000 mL 2000 mL 3000 mL

19
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Opticap® XL and XLT Sterile and Gamma-Compatible Capsule Filter Specifications Overview
Selection & Applications Guide
Opticap® Opticap® Opticap® Opticap® Opticap®
Description XL 4 XL 10 XLT 10 XLT 20 XLT 30 Formats
NVR Gravimetric Extractables — ≤ 25 mg ≤ 25 mg ≤ 50 mg ≤ 75 mg OptiScale® Capsules
Bacterial Endotoxin Aqueous extraction contains < 0.25 Aqueous extraction contains < 0.5 EU/mL as determined by the Cartridge Filters
EU/mL as determined by the Limulus Limulus Amebocyte Lysate (LAL) Test. This meets the requirements
Amebocyte Lysate (LAL) Test. This meets of USP <85>. Cartridges
the requirements of USP <85>.
Optiseal® Cartridges
Bacterial Retention Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology.
Millidisk® Cartridges
Sterilization
Gamma-compatible: Gamma-compatible to 45 kGy. May be autoclaved for 3 cycles of 60 minutes at 123 °C. (Cannot be steam
sterilized in-line.) Capsule Filters
Sterile: May be autoclaved for 3 cycles of 60 minutes at 123 °C. (Cannot be steam sterilized in-line.)
Opticap® XL and XLT Capsules
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Total Organic Carbon (TOC) / Gamma sterilized — — — — Filters for Final Filtration
Conductivity filter effluent
meets the WFI Millipak® Final Fill Capsules
requirement of USP
<643>, for Total M
 illidisk® Barrier Cartridges
Organic Carbon and Millipak® Barrier Capsules
and USP <645> for
Water Conductivity
at 25 °C after a WFI
flush of 26 L. Durapore® 0.1 μm & 0.22 μm
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. Durapore® 0.45 μm
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on Durapore® 5.0 μm
information provided by raw material suppliers.
Multimedia Durapore®
*Cage, core, end caps, and capsule housing
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

20
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Millipak® Final Fill Capsule Filter Specifications Overview

Millipak® Final Fill Millipak® Final Fill Selection & Applications Guide
Description Millipak® Final Fill 20 Millipak® Final Fill 40 Millipak® Final Fill 60 100 200 Formats
Nominal Dimensions
OptiScale® Capsules
Maximum length 8.1 cm (3.2 in.) 8.6 cm (3.4 in.) 10.9 cm (4.3 in.) 11.9 cm (4.7 in.) 14.5 cm (5.7 in.)
Body diameter 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) Cartridge Filters
Body diameter – – – 8.1 cm (3.2 in.) 8.1 cm (3.2 in.) Cartridges
w/ anti-roll edges
Filtration area 100 cm (0.11 ft )
2 2
200 cm (0.22 ft )
2 2
300 cm (0.32 ft )
2 2
500 cm (0.54 ft )
2 2
1000 cm (1.08 ft )
2 2 Optiseal® Cartridges
Aseptic Multi-Purpose Port (AMPP) 3.2 mm (1/8 in.) hose barb Millidisk® Cartridges
Materials of Construction
Filter membrane: Durapore® PVDF (polyvinylidene fluoride) membrane
Support discs: Polysulfone
Capsule Filters
Filter capsule: Polysulfone Opticap® XL and XLT Capsules
Aseptic Multi-Purpose Port (AMPP) Polyethersulfone
AMPP O-rings: Silicone Filters for Final Filtration
Hold-up Volume 20 psi above the Bubble Point Specification for 1 minute
1.1 mL 1.5 mL 3.2 mL 4.8 mL 7.2 mL Millipak® Final Fill Capsules
Maximum Inlet Pressure 60 psi (4.1 bar) 80 psi (5.5 bar) at 25 °C M
 illidisk® Barrier Cartridges
at 25 °C and Millipak® Barrier Capsules
Maximum Differential Pressure

Forward: 60 psi (4.1 bar) at 25 °C 80 psi (5.5 bar) at 25 °C Durapore® 0.1 μm & 0.22 μm
25 psi (1.7 bar) at 80 °C
Durapore® 0.45 μm
Reverse: 10 psi (0.7 bar) at 25 °C
Bubble Point at 23 °C Durapore® 5.0 μm
0.1 μm: ≥ 70 psi (4830 mbar) air with water* Multimedia Durapore®
0.22 μm: ≥ 50 psi (3450 mbar) air with water
Bacterial Retention for Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology.
Charged Durapore® 0.22 μm
0.1 μm and 0.22 μm Multilayer Durapore®
Microbial Challenge Testing Vents were tested utilizing a bacterial challenge method with 107 B. Diminuta assuring a sterile fluid path during actuation.
Bacterial Endotoxin Aqueous extraction contains < 0.25 EU/mL per device as determined using the Limulus Amebocyte Lysate (LAL) test,
Durapore® CBR 0.1 μm &
meeting requirements of USP <85>, EP 2.6.14 and JP 4.01. 0.2 μm
Total Organic Carbon (TOC) / Samples exhibited < 500 ppb TOC per USP <643> and < 1.3 μS/cm conductivity per USP <645> at 25 °C after Hydrophobic Durapore®
Conductivity sterilization and a water flush of:
0.22 μm
1.0 L 2.0 L 2.0 L 3.0 L 5.0 L
Hydrophobic-hydrophilic
Sterilization Device integrity and retention was maintained after 3 autoclave cycles of 90 minutes at 126 °C. Devices can
withstand a dose ≤ 40 kGy gamma exposure. Durapore® 0.22 μm
Toxicity Component materials meet the criteria for Class VI testing based on USP <88> Biological Reactivity, in vivo,
USP <87> Biological Reactivity, in vitro, and ISO 10993-5 Tests for in vitro Cytotoxicity. This product also meets
physicochemical specifications, as described in USP <661> Containers-Plastics. Contact Information
Particle Shredding Effluent meets the acceptance criteria set forth in USP <788> for large volume parenterals.
Non-Fiber Releasing This product was manufactured with a Durapore® membrane which meets the criteria for a “non-fiber releasing” filter
as defined in 21 CFR 210.3 (b)(6), validated based on large volume parenteral specifications as detailed in USP <788>
Particulate Matter in Injections.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177–182, based on
information provided by raw material suppliers.
Quality Management System These products are manufactured in a facility which is certified to ISO® 9001:2015 Quality Management Systems. 21
*Transient pressure excursion above the maximum differential and inlet pressures of the unit for integrity testing and capsule blow-down is acceptable.
 TTTT==38
38mmmm(1½(1½in.)in.)Sanitary
Sanitary
Flange
FlangeInlet
InletandandOutlet
Outlet
THTH==3838mm
mm(1½ (1½in.)in.)Sanitary
Sanitary
Flange
FlangeInlet
Inletandand16 mm(5(/58/8in.)
16mm in.)
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane HH
Hose
HH==16
HoseBarb
16mm
BarbOutlet
Outlet
mm(5(/58/8in.)
in.)Hose
HoseBarb
BarbInlet
Inletand
andOutlet
Outlet
Durapore® Family Guide
BBBB==2525mm
mm(1(1in.)in.)Hose
HoseBarb
BarbInlet
Inletand andOutlet
Outlet
Typical Clean Water Flow Rates – Cartridge Filters Overview
Selection & Applications Guide
Cartridge Filters — 0.22 μm Formats
Cartridge
CartridgeFilters
Cartridge Filters
Filters — 0.1 μm Hydrophilic Durapore®
Cartridge
CartridgeFilters
Durapore Filters
® ——
Membrane Cartridge
CartridgeFilters
Membrane Filters—— OptiScale® Capsules
0.1
0.1µm
µmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane 0.22
0.22µm
µmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane
Cartridge Filters
Cartridges
Optiseal® Cartridges
Millidisk® Cartridges

Capsule Filters
Opticap® XL and XLT Capsules

99
Filters for Final Filtration
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Typical Clean Water Flow Rates – Millidisk® Cartridge Filters
Durapore® 5.0 μm
Millidisk®
Millidisk ®
Water Flow
Cartridge Filters Rates atMillidisk
25 °C ® Cartridge Filters Multimedia Durapore®
— 0.1 μm Durapore® — 0.22 μm Hydrophilic Charged Durapore® 0.22 μm
Membrane
Millidisk®
Millidisk® 0.1
0.1 µm
µm Hydrophilic
Hydrophilic Filters
Filters Durapore
Millidisk®
Millidisk® 0.22 Membrane
0.22®µm
µm Hydrophilic
Hydrophilic Filters
Filters Millidisk®
Millidisk® 0.22
0.22 µm
µm Hydrophobic
Hydrophobic Filters
Filters
Multilayer Durapore®
L/min L/min
L/min L/min
L/min
L/min
Durapore® CBR 0.1 μm &
00 22 44 66 88 10 12 00 10 20 30 40 50 00 55 10
10 15
15 20
20 25
25 30
30 35
35
10 12 14
14 16
16 18
18 20
20 22
22 10 20 30 40 50
50 50
50 50
50
50
(psid)

0.2 μm
(psid)

Pressure (psid)
(psid)

45
Pressure (psid)
Pressure (psid)

45
45 45
45 3.0 45 3.0
3.0
3.0
3.0 3.0
40 40
40 40
40
40
Differential Pressure

2.5
Differential Pressure
Differential Pressure

2.5 2.5 2.5

Hydrophobic Durapore®
2.5 2.5 35
35
35 35
35 35
30 30
30 30
30 2.0
30 2.0 2.0 2.0
0.22 μm
2.0 2.0
25
Differential

25 25
Differential

25
Differential

25 25
1.5 1.5
1.5 1.5
1.5
20 1.5 20
20 20
20
20
15
15 MCVL
MCVL10S
10S03
03 1.0
1.0
15
15 MCGL
MCGL10S
MCGL
10S03
03 1.0
1.0
15
15 MCGB
MCGB10S
MCGB
10S02
MCGB20S
02
20S02
1.0
1.0 Hydrophobic-hydrophilic
MCVL
MCVL20S
20S03
03 MCGL20S
20S03
03 10 02
Durapore® 0.22 μm
10
10 10
10 10 MCGB
MCVL
MCVL30S
30S03
03 0.5 MCGL
MCGL30S
30S03
03 0.5 MCGB30S
30S01
01 0.5
0.5
0.5 55 0.5 55 MCGB 40S 01
55 MCVL
MCVL40S
40S03
03 MCGL
MCGL40S
40S03
03 MCGB 40S 01
bar

00
bar

bar

0.0
bar

00
bar

00 0.0 0.0
bar

0.0
0.0 0.0
00 11 22 33 44 55 66 00 22 44 66 88 10
10 12
12 14
14 00 11 22 33 44 55 66 77 88 99 10
10

Flow
Flow Rate
Rate (L/min)
(L/min) Flow
Flow Rate
Rate (L/min)
(L/min) Flow
Flow Rate
Rate (L/min)
(L/min)
Contact Information

Millidisk®
Millidisk® 0.45
0.45 µm
µm Hydrophilic
Hydrophilic Filters
Filters Millidisk®
Millidisk® 5.0
5.0 µm
µm Hydrophilic
Hydrophilic Filters
Filters Millidisk®
Millidisk® 0.22
0.22 µm
µm Hydrophobic
Hydrophobic Filters
Filters
Air
Air Flow
Flow Rate
Rate @
@ 25
25 ºC
ºC
L/min
L/min L/min L/min
L/min
L/min
00 10
10 20
20 30
30 40
40 50
50 60
60 70
70 00 200 400 600 800 1000 1200 1400

22
00 10
10 20
20 30
30 40
40 50
50 60
60 70
70 200 400 600 800 1000 1200 1400
50
50 50
50 10
10 .7.7
(psid)
Pressure (psid)

45
(psid)

(psid)

45 MCSL
MCSL10S
10S02
Pressure (psid)

Pressure (psid)

3.0
3.0 45
45 02 3.0
MCSL 3.0
40 MCSL20S
20S02
02
40 40
40 MCSL 88
MCSL30S
30S01
ntial Pressure

2.5
2.5 01
ntial Pressure

tial Pressure

35 2.5
2.5
35 35
35 MCSL
MCSL40S
40S01
01
30
30 2.0 30
2.0 30 2.0
2.0 66
ential

25
25
ntial

25
ntial

25 .35
.35
1.5
1.5 1.5 MCGB
MCGB10
10
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Typical Clean Water Flow Rates – Opticap® XL Autoclavable Capsules Overview

Selection & Applications Guide
Opticap®
Opticap ®
XL 2XLCapsules
Capsule
Opticap®Filters
—
XL 0.1
Capsule
Opticap® XL Capsule Opticap
μmFilters Filters ® XL 2 Capsules — 0.22 μm Opticap® XL 4 Capsules — 0.1 μm
Opticap®
Opticap® XL
XL 2 Capsule
Opticap®
Capsule Filters
XLXL
Filters
Opticap® 2—Capsule
Opticap®
Capsule
Opticap®Filters
XL2—Capsule
Filters
XL Filters—
Capsule Filters Opticap® XL 4 Capsule Filter
Opticap® XL —
4 Capsule
Opticap®
®Filter
XL —4 Capsule Filter —
Formats
Opticap®
Durapore ® XL Capsule
Membrane
Opticap® XL 2 Capsule
Filters
Opticap®
Opticap® XL
Filters
XL 2 Capsule
— Capsule
Opticap®Filters
Filters Hydrophilic
XL 2—Capsule Filters — Durapore ®
Membrane
Opticap® XL 4 Capsule
Opticap®Durapore
Filter
XL—4 Capsule
Opticap®Membrane
Filter
XL 4—Capsule Filter —
0.1 µm Hydrophilic
0.1Durapore®
µmFilters —Membrane
Hydrophilic
0.1 Durapore®
µm Hydrophilic
—Membrane
Durapore® Membrane 0.1 µm Hydrophilic
0.1Durapore®
µmFilter Membrane
Hydrophilic
0.1 Durapore®
µm Hydrophilic
—Membrane
Durapore® Membrane
Opticap® XL 2 Capsule
Opticap®
0.1 µm Hydrophilic XL 2
0.1Durapore® Capsule
µm Hydrophilic µmFilters
Membrane
0.1 Durapore®
Hydrophilic
Membrane
Durapore® Membrane
Opticap® XL 4 Capsule
Opticap®
0.1 µm Hydrophilic XL—4Membrane
0.1Durapore® Capsule
µm Hydrophilic µmFilter
0.1 Durapore®
Hydrophilic
Membrane
Durapore® Membrane OptiScale® Capsules
0.1 µm Hydrophilic
0.1Durapore® Membrane
µm Hydrophilic Durapore® Membrane 0.1 µm Hydrophilic
0.1Durapore® Membrane
µm Hydrophilic Durapore® Membrane
Cartridge Filters
Cartridges
Optiseal® Cartridges
Millidisk® Cartridges

Capsule Filters
Opticap® XL and XLT Capsules

Opticap ®
XL XL
Opticap® 4 4Capsules
Capsule
Opticap® XL—4—0.22
Filters Capsuleμm
Opticap®
Filters Opticap®
XL 4—Capsule Opticap ®
XL 5—Capsule
Filters XL 5 5Capsules
Filters
Opticap® XL —Capsule
Opticap® XL—5—Capsule
Filters 0.1 μm
Opticap® XL 5—Capsule
Filters Opticap
Filters
Opticap®
®
XL 5—Capsule XL
Opticap® 5 5Capsules
Filters
XL ——0.22 μm
—Capsule Filters Filters for Final Filtration
Opticap®
0.22 µm
Hydrophilic XL 4 Capsule
Opticap®
Hydrophilic
Durapore
0.22 Filters
µm XL 4
Durapore® — Capsule
Opticap®
Membrane
Membrane
® Hydrophilic
0.22 Filters
Durapore®
µm Opticap®
XL 4—Capsule
0.1
Hydrophilicµm
Membrane XL 5—Capsule
Filters Opticap®
Hydrophilic
Durapore
Durapore® 0.1 Filters
XL 5
Durapore®
µm
Membrane —Membrane
MembraneCapsule
Opticap®
Hydrophilic
0.1 Filters
XL 5—Capsule
Durapore®
µm 0.22
Hydrophilic Filters
Opticap®
µm
Membrane XL 5—Capsule
Opticap®
Hydrophilic
Durapore® Filters
XL 5
Durapore®
Membrane
0.22 µm — Capsule
Opticap®
Membrane
Hydrophilic
Hydrophilic Filters
XL 5—Capsule
Durapore Filters — Membrane
Membrane
Opticap® XL 4 Capsule Filters
Opticap® XL 4— Capsule Filters — Opticap® XL 5 Capsule ®
Filters
Opticap® XL 5— Capsule Filters — Opticap® XL 5 Capsule Filters
Opticap® XL 5— CapsuleDurapore®
0.22 µm Hydrophilic
Filters — Membrane
Durapore®
®
Millipak® Final Fill Capsules
0.22 µm Hydrophilic
0.22Durapore®
µm Hydrophilic
Membrane
0.22 Durapore® 0.1 µm
µm Hydrophilic Hydrophilic
Membrane
Durapore® 0.1Durapore®
µm Hydrophilic
Membrane Membrane
0.1 Durapore®
µm Hydrophilic
Membrane
0.22Durapore® Membrane
µm Hydrophilic
0.22Durapore®
µm Hydrophilic
Membrane
0.22 Durapore®
µm Hydrophilic
Membrane
Durapore® Membrane
0.22 µm Hydrophilic
0.22Durapore® Membrane
µm Hydrophilic 0.1 µm Hydrophilic
Durapore® Membrane 0.1Durapore® Membrane
µm Hydrophilic 0.22 µm Hydrophilic
Durapore® Membrane 0.22Durapore® Membrane
µm Hydrophilic Durapore® Membrane
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Opticap®
Opticap ® XL
XLXL1010Capsules
Capsule
Opticap®Filters
XL —10—Capsule
Opticap®
0.1 μm Filters Opticap®Opticap
XL 10—Capsule XL 10—Capsule
Filters Filters
Opticap®
® XL 10
XLFilters
10 —Capsule
Opticap®Filters
Capsules XL—10— Opticap®
Capsule
0.22 μm XL Capsule
Filters Legends
— Opticap® Refer
XL Capsule
Opticap®
Legends
XL Capsule
Refer Legends Refer Multilayer Durapore®
Opticap®
0.1 µm 10 Capsule
Opticap®
µm Filters
XL 10 —Opticap®
Capsule Filters Opticap®
XL 10—Capsule XL 10Membrane
µmFilters —Capsule
Opticap® XL 10—Membrane
Opticap®
Capsule Filters Opticap®
XL 10—Capsule XL Capsule
Filters
to Connection Opticap®
—Type Legends
XL Refer
Capsule
Opticap®
Legends
XL Capsule
Refer Legends Refer
® Hydrophilic
Opticap® 0.1Durapore®
XL 10 Capsule Filters Membrane
Hydrophilic
0.1 Durapore®
— Capsule 0.22Durapore®
µm Hydrophilic
Filters Membrane
Opticap® Hydrophilic
0.22
XL 10 CapsuleDurapore®
µmFilters
Hydrophilic
0.22 Durapore®
µm
® Hydrophilic
— Capsule —Membrane
Durapore®
Opticap® to Connection
Membrane
XL Capsule Opticap
Legends Type
to
XL Refer
® Connection
XL CapsuleTypeLegends Refer
Durapore MembraneOpticap®
0.1 µm Hydrophilic XL 10
0.1Durapore®
µm Hydrophilic
Membrane
0.1 Durapore® —0.22
µm Hydrophilic µmHydrophilic
Membrane Hydrophilic
Durapore® 0.22 µm Durapore
Opticap® XL 10
Durapore®
Membrane Hydrophilic
Membrane Membrane
µmFilters
0.22 Durapore® to Connection
Hydrophilic Durapore® Type
Membrane Opticap®
Membrane Capsule
to Connection Type Legends
to Connection Refer
Type Durapore® CBR 0.1 μm &
0.1 µm Hydrophilic
0.1Durapore® Membrane
µm Hydrophilic 0.22 µm Hydrophilic
Durapore® Membrane 0.22Durapore® Membrane
µm Hydrophilic to
TT Connection
Durapore® Membrane
= 38 mm (1½ Type to
in.)
TT = 38to mmConnection
Connection
Sanitary Flange
(1½ Type
TT
in.)=Sanitary
38 mm Type(1½
Flange in.) Sanitary Flange
TT = 38 mm
Inlet (1½
and in.)
OutletTT =Sanitary
38 mm
Inlet and Flange
(1½ TT
in.)= Sanitary
Outlet 38
Inletmm and(1½
Flange in.) Sanitary Flange
Outlet
0.2 μm
TT = 38 mm (1½ in.) TT
Sanitary
TT = Inlet
38 mm =  38
Flange mm (1½ in.) Sanitary Flange Inlet
Inlet and Outlet and(1½ in.) Sanitary
Outlet Inlet andFlange Outlet
FF = Inlet
19 mm and(¾ Outlet
in.)
FF Sanitary
= Inlet
19 mm andFlangeand
(¾Outlet
in.)
FF = Outlet
Sanitary
19 mmFlange (¾ in.) Sanitary Flange Hydrophobic Durapore®
FF = 19 mm
Inlet (¾Outlet
and in.)
FFSanitary
= Inlet
19 mm Flange
and(¾Outlet
in.)
FF =Sanitary
19
Inletmm andFlange
(¾Outlet
in.) Sanitary Flange
FF = 19 mm (¾ in.)
Inlet and Outlet FF Sanitary
= 19 FF
Inletmm Flange
= 
and 19in.) mm
(¾Outlet Sanitary
Inlet (¾and in.)
Flange
Outlet Sanitary Flange Inlet 0.22 μm
HH =Inlet and (Outlet
14 mm 9 /16HH in.)=Hose
Inlet
14 Barb
mmand ( /Inlet
9Outlet
16HH
and in.)= Hose
14
Outlet mmBarb ( Inlet
9/16 in.) Hose Barb Inlet
HH = 14 mm
andmm (9/16 HH
Outlet in.) =Hose
14
and Barb
mm (
Outlet
9Inlet
/ HH
16 in.)
= Hose
14 mmBarb
and Outlet (9/16Inlet
in.) Hose Barb Inlet Hydrophobic-hydrophilic
HH = 14 (9/16 in.) Hose Barb (9Inlet
/16 in.) Hose Barb in.)Inlet Hose Barb Inlet
and Outlet HH = and 14HH mm = 
Outlet 14 mm and(⁹⁄₁₆
Outlet
TH = 38
TH = 38
andmm
mm
Outlet
(1½ TH
(1½
in.)=Sanitary
andmm
38 Flange
Outlet
(1½ and TH
in.)=Outlet
Sanitary
38 mm (1½ Flange in.) Sanitary Flange Durapore® 0.22 μm
TH = 38Inlet
mm and(1½ 14in.)
THmm=Sanitary
in.) (38
9/16mm
Inlet
Sanitary in.)
andFlange
(1½14TH
Hose
Flange
in.)
mm= Sanitary
38
(99/16mm
Inlet in.)
and(1½
Flange
14in.)
Hose mmSanitary
(9/16 in.)Flange
Hose
Inlet
Barb and 14 TH
Outlet mm=(Barb38 TH
Inlet
9/16 mm
in.)
and(1½
= 
Hose
Outlet
38in.)
14 mm
mm Sanitary
Inlet
( (1½
/16
Barb in.)
and Flange
in.)
Hose
Outlet14 mm Sanitary Flange Inlet
(9/16 in.) Hose
Inlet and 14 mm (Inlet 9 /16 in.)
andHose
14 mm ( 9/16 in.) Hose
Barb Outlet Barb Outlet and 14 Barb mm Outlet(9/16 in.) Hose Barb Outlet
FH = Barb
19 mm Outlet
(¾ in.) FH Sanitary
= Barb
19 mm Flange
Outlet
(¾ in.) FH = Sanitary
19 mmFlange (¾ in.) Sanitary Flange
FH = 19
FH = 19
mm
Inlet
mm and(¾14
(¾ in.)
in.)
FHmm 9/FH
Sanitary
= (19 16mm
Inlet
Sanitary
= 
Flange
in.)
and(¾ 19
Hose
14
Flange
in.)
FHmmmm
=Sanitary
19
Inlet(¾
mm
(99/16 in.)
Flange
in.)
and(¾ Hose
14in.)Sanitary
mmSanitary Flange
Hose Inlet
Flange
(99/16 in.) Contact Information
Inlet
Barb and 14 FH
Outlet mm=2(19 9/16mm
Inlet in.)
4and
(¾
Hose
14
andin.)
mm Sanitary
2Inlet
14 (andmm
/16 Flange
in.)
and Hose
14 (XL
(9/16 mm 2( and
in.) in.)
/16Hose Hose
Barb Outlet
Inlet and 14 (XL 9and
Barb
mm (Inlet /16 in.) only)
Outlet
andHose
14 (XL
mm Barb
( 4Outlet
9/16 in.)only)
Hose 4 only)
Barb Outlet (XL 2 Barb and 4Outlet
only) (XL (XL22Barband Outlet
and 44only)
only) (XL 2 and 4 only)
Barb Outlet (XL 2 Barb and 4Outlet
only) (XL 2 and 4 only)

23
 0 0 5 5 10 10 15 15 20 10 20 10
Flow Rate
Flow
(L/min)
Rate (L/min)

psid

psid
Flow Rate
Flow
(L/min)
Rate (L/min)

psid

psid
0.0 0.0 0 0 0.0 0.0 0 0
0 02 24 46 68 10
8 1012 12 0 0 5 5 10 10 15 15 20 20
Millipak 100/200
Millipak Capsule
100/200Filter
Capsule Filter Millipak 100/200
Millipak Capsule
100/200Filter
Capsule Filter
0.1Flow RateFlow(L/min)
Rate (L/min)
0.22 Flow Rate Flow
(L/min)
Rate (L/min)
Millipak®
Millipak®
Capsule
Capsule
Legends
Legends
RefersRefers
to Connection
to Connection
Type Type 0.1 µm Hydrophilic
µm Hydrophilic
Durapore Durapore
Membrane Membrane
(MPVL) (MPVL) 0.22 µm Hydrophilic
µm Hydrophilic
Durapore Durapore
Membrane Membrane
(MPGL) (MPGL)

Filters Containing toDurapore 0.1 μm and 0.22 μm Membrane

14Millipak
9mm 100/200
Millipak Capsule
100/200Filter
(9Durapore Capsule Filter
A =A 140.1
=
mm (0.1
/16 in.)®/16Hose
in.) Barb
Hose Inlet
Barb andInletOutlet
and Outlet
Durapore® Family Guide
Millipak 100/200
Millipak Capsule
100/200Filter
Capsule Filter
Millipak®
Millipak®
Capsule
Capsule
LegendsLegends
RefersRefers
to Connection
Connection
Type Type
µm Hydrophilic
µm Hydrophilic Durapore
Membrane Membrane
(MPVL) (MPVL) 0.22 µm Hydrophilic
0.22 µm Hydrophilic
Durapore Durapore
Membrane Membrane
(MPGL) (MPGL)

F =F 19 = mm19( mm
/ in.)
( /Sanitary
in.) Sanitary
FlangeFlange
Inlet and34
InletOutlet34
and Outlet
A =A 14 =
mm14(9mm (9/16Hose
/16 in.) in.) Barb
Hose Inlet
Barb and
InletOutlet
and Outlet
L =L 38 =
mm 1/2 in.)
38(13mm (13 1/Sanitary
2 in.) Sanitary
FlangeFlange
Inlet and
InletOutlet
and Outlet
F =F 19 =
mm19( mm
/4 in.)
( /Sanitary
4 in.) Sanitary
FlangeFlange
Inlet and
InletOutlet
and Outlet
Typical Clean
1 1
Water Flow Rates - Opticap® XL Sterile and Gamma-Compatible Capsules Overview
L =L 38 =
mm38(1mm
/2 in.)
(1 /Sanitary
2 in.) Sanitary
FlangeFlange
Inlet and
InletOutlet
and Outlet
Opticap®
Opticap®
XL Capsule
XL Capsule
FiltersFilters Selection & Applications Guide
Opticap® XL 4 Capsules — 0.1 μm Opticap® XL 4 Capsules — 0.22 μm Formats
Opticap®
Opticap®
® XLXL
Opticap® 4 Capsule
Opticap® XL 4 Capsule
Capsule
XL Filters
Capsule Filters
– Filters
Filters – Opticap®
Opticap®
XL 4 Capsule
XL 4 Capsule
FiltersFilters
– –
Durapore Membrane Hydrophilic Durapore® Membrane
0.1 µm0.1
Hydrophilic
µm Hydrophilic
Durapore®
Durapore®
Membrane
Membrane 0.22 µm
0.22Hydrophilic
µm Hydrophilic
Durapore®
Durapore®
Membrane
Membrane
Opticap®
Opticap®
XL 4gpmCapsule
XL 4 Capsule
FiltersFilters
– – Opticap®
Opticap®
XL 4 gpm
Capsule
XL 4 Capsule
FiltersFilters
– – OptiScale® Capsules
gpm gpm
0.1 µm0.1
0Hydrophilic
µm10Hydrophilic
21 Durapore®
32 Durapore®
43 Membrane
54 Membrane 0.22 µm
0.22
0Hydrophilic
µm 0Hydrophilic
Durapore®
3 6 Durapore®
6 Membrane
Membrane
4.0
65 6
4.0
3 9 9 12
5.0
12
5.0
70 70
Cartridge Filters
gpm gpm gpm gpm

Cartridges
32 43 54 65 50
6 50
0 10 21 0 0 3 3 6 6 9 9 12 12
60 60
4.0 4.0 4.0
5.0 4.0
5.0
3.0 3.0 70 70

(bar)Drop (bar)

(bar)Drop (bar)
40 40 50 50
50 50
Optiseal® Cartridges
(bar)Drop (bar)

(bar)Drop (bar)

3.0 3.0 60 60
4.0 4.0 40 40
3.0
2.0 3.0
2.0 30 30
40 40 50 50

Pressure

Pressure
2.0
3.0
2.0
3.0
30 30
Millidisk® Cartridges

Pressure Drop

Pressure Drop
Pressure

Pressure

20 20 40 40
2.0 2.0 30 30 20 20
Pressure Drop

Pressure Drop

1.0 1.0
1.0 1.0 30 30
10 10 2.0 2.0
10 10
20 20
20 20
Capsule Filters
psid

psid

1.0
0.0 1.0
0.0 0.0 0.0 0 0
0 0 1.0 1.0
0 0 5 5 10 1015 15 20 2025 10 25 10 0 5 0 10 5 15 1020 1525 2030 2535 30 40 3545 4050 45 50
10 10

Flow Rate
Flow
(L/min)
Rate (L/min) Flow Rate
Flow
(L/min)
Rate (L/min) Opticap® XL and XLT Capsules
psid

psid

0.0 0.0 0 0 0.0 0.0 0 0

0 0 5 5 10 1015 15 20 2025 25 0 5 0 10 5 15 1020 1525 2030 2535 30 40 3545 4050 45 50
Opticap Opticap
XL4 withXL4
Hydrophilic
with Hydrophilic
DuraporeDurapore
MembraneMembrane Opticap Opticap
XL 4 with
XLHydrophilic
4 with Hydrophilic
DuraporeDurapore
MembraneMembrane
Opticap®
Opticap®
XL 10 XLCapsule
100.1Capsule
Flow RateFilters
Flow
µm Filters
(L/min)
Rate
(KVVL)
0.1 µm –(L/min)
(KVVL)– Opticap®
Opticap®
XL 10 XLCapsule
10 Flow
Capsule
0.22Filters
µm 0.22
Rate Filters
–µm
(KVGL)
Flow –
Rate(KVGL)
(L/min) (L/min)

Opticap
0.1 µm
®0.1
XL
Opticap 10
Hydrophilic
µmOpticap
XL4 Capsules
Hydrophilic
withDurapore®
XL4 withDurapore®
Hydrophilic Membrane
Hydrophilic
Durapore — 0.1
Membrane
Durapore
Membrane μm
Membrane Opticap
0.22 µm
0.22 µmXL
Hydrophilic
®
Opticap 10
Hydrophilic
Opticap
XL Capsules
Durapore®
4 with
XL Durapore®
Hydrophilic
4 with Membrane
Hydrophilic
Durapore —Membrane
Membrane
Durapore
Membrane 0.22 μm Filters for Final Filtration
Opticap®
Opticap®
XL 10 XL
Capsule
100.1Capsule
µmFilters Filters
(KVVL)
0.1 µm –(KVVL)– Opticap®
Opticap®
XL 10 XL
Capsule
10 0.22
Capsule
Filters
µm0.22 Filters
–µm (KVGL)
(KVGL) –
Durapore®0gpmMembrane
gpm
Hydrophilic
gpm gpm
Durapore ®
Membrane Millipak® Final Fill Capsules
0.1 µm0.1
Hydrophilic
µm 0Hydrophilic
5 Durapore®
5 10 Durapore®
Membrane
10 15 Membrane
15 20 20 0.22 µm
0.22
0 Hydrophilic
µm 0 Hydrophilic
5 Durapore®
5 10 Durapore®
10 Membrane
15 Membrane
15 20 20
2.5 2.5 2.5 2.5
35 35 35 35
M
 illidisk® Barrier Cartridges
gpm gpm T T TT gpm gpm
TT TT
2.0
0
2.0
0 5FF
HH
5FF 10
HH
10 15 15 20 3020 30 2.0
0
2.0
0 5 FF 5 FF10 10 15 15 20 30 20 30 Opticap® XL Capsule Legends Refer
and Millipak® Barrier Capsules
2.5 2.5 2.5 2.5 HH HH
TH
TT
FH
TH
TT
FH
35
25
35
25
TH
TT
TH
TT
35
25
35
25 to Connection Type
FF FF FH FH
Drop (bar)Drop (bar)

Drop (bar)Drop (bar)

Drop (bar)

Drop (bar)

30 30 1.5 1.5 FF FF 30 30
1.5 1.5 2.0 2.0
2.0 2.0 HH
TH
HH
TH 20 20 HH
TH
HH
TH
20 20 TT = 38 mm (1½ in.) Sanitary Flange Inlet
25 25
FH FH 25 25
1.0 1.0 FH FH 15 15 and Outlet
Drop (bar)

Drop (bar)

15 15 1.5 1.5
Durapore® 0.1 μm & 0.22 μm
1.0 1.0
Pressure Pressure

Pressure Pressure

1.5 1.5
Pressure Pressure

Pressure Pressure

20 20
20
10
20
10
10 10 FF = 19 mm (¾ in.) Sanitary Flange Inlet
0.5 0.5
1.0 1.0 15 15
and Outlet
Durapore® 0.45 μm
0.5
1.0 0.5
1.0 15 15 5 5
5 5
10 10
HH = 14 mm (⁹⁄₁₆ in.) Hose Barb Inlet

psid

psid
10 10 0.0 0.0 0 0
psid

psid

0.5 0.5
Durapore® 5.0 μm
0.0
0.5 0.0
0.5 0 0 0 10 0 2 010 302 0 4 030 504 0 6 050 706 0 8 0705 805
0 100 2010 30
20 40
30 5040 6050 7060 70
805 805 and Outlet
Flow Rate
Flow
(L/min)
Rate (L/min)
psid

psid
Flow Rate
Flow
(L/min)
Rate (L/min) 0.0 0.0 0 0
TH = 38 mm (1½ in.) Sanitary Flange Inlet
psid

psid

0.0
0
0.0
100 2010 30
20 40
30 5040 6050 7060 70
80
0
80
0 0
Opticap XL
Opticap
10 0
2 010 302 0 4 030 504 0 6 050 706 0 8 070
10 Capsule
XL 10Filter
Capsule Filter
80
and 14 mm (9/16 in.) Hose Barb Outlet
Multimedia Durapore®
0.22 µm 0.22Flow Rate
Hydrophilic Flow
(L/min)
µm HydrophilicRate
Durapore (L/min)
Durapore
Membrane Membrane
(KVGL) (KVGL)
Opticap®
Opticap®
XL Capsule
XL Capsule Legends Legends
Refer Refer Flow XL
Opticap Rate
Flow
10 (L/min)
Opticap Rate
Capsule
XL (L/min)Filter
10 Filter
Capsule
0.1 µm Hydrophilic
0.1 µm Hydrophilic
DuraporeDurapore
Membrane Membrane
(KVVL ) (KVVL ) FH = 19 mm (¾ in.) Sanitary Flange Inlet Charged Durapore® 0.22 μm
to Connection
to Connection
Type Type Opticap XL
Opticap
10 Capsule
XL 10Filter
Capsule Filter
0.22 µm 0.22
Hydrophilic
µm Hydrophilic
Durapore Durapore
Membrane Membrane
(KVGL) (KVGL) and 14 mm (9/16 in.) Hose Barb Outlet
Opticap®
Opticap®
XL
TT =TT38 =
mm Capsule
XL1 Capsule
Opticap Legends
XL
Opticap
1
10 Legends
Capsule
XL 10Refer
CapsuleRefer
Filter Filter
Multilayer Durapore®
0.138
µm(1mm /2µmin.)
Hydrophilic
0.1 /Durapore
Sanitary
2 in.) Durapore
(1Hydrophilic Sanitary
Flange
Membrane Flange
Inlet
Membrane
(KVVL and
Inlet
) (KVVL ) Outlet
and Outlet (XL 2 and 4 only)
to Connection
to Connection
Type Type
FF =FF19 =
mm 19(3mm/4 in.) (3/Sanitary
4 in.) Sanitary
FlangeFlangeInlet andInletOutlet
and Outlet
TT =TT38 =
mm 38(19mm1/2 in.)
(19 1/Sanitary
2 in.) Sanitary
FlangeFlangeInlet and
InletOutlet
and Outlet Durapore® CBR 0.1 μm &
HH =HH14 =
mm 14( mm/16 in.)( /16Hose in.) Barb
Hose InletBarb andInletOutlet
and Outlet
FF =FF19 =
mm
TH =TH38 =
mm
19(3mm
38(1mm
/14 in.)(3/Sanitary
/2 in.)
4 in.) Sanitary
(11/Sanitary
FlangeFlange
2 in.) Sanitary
Inlet and
FlangeFlange
InletOutlet
Inlet and
and Outlet
Inlet14and
mm14(9mm (9/16Hose
/16 in.) in.) Hose
Barb Outlet
Barb Outlet
0.2 μm
HH =HH14 =
mm 14(9mm/16 in.)(9/16Hose in.) Barb
Hose InletBarb andInletOutlet
and Outlet 9
FH =FH19 =
mm 19(3mm/4 in.) (3/Sanitary
1/2 in.)
4 in.) Sanitary
FlangeFlangeInlet andInlet14and
mm14( mm (9/16Hose
/16 in.) in.) Barb
Hose Outlet
Barb Outlet Hydrophobic Durapore®
TH =TH38 =
mm 38(1mm (11/Sanitary
2 in.) Sanitary
FlangeFlangeInlet and
Inlet14and
mm14(9mm (9/16Hose
/16 in.) in.) Hose
Barb Outlet
Barb Outlet
FH =FH19 =
mm 19(3mm/4 in.) (3/Sanitary
4 in.) Sanitary
FlangeFlangeInlet andInlet14and
mm14(9mm (9/16Hose
/16 in.) in.) Barb
Hose Outlet
Barb Outlet
0.22 μm
Hydrophobic-hydrophilic
5 5 Durapore® 0.22 μm
5 5

Contact Information

24
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Typical Clean Water Flow Rates - Opticap XLT Autoclavable Capsules Overview

QTJE
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Selection & Applications Guide

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Typical
Typical Clean
Clean Water
Water Flow
Flow Rates
Rates

QTJE
   

ow Rates                                  

Opticap XLT
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10
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JODI
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 JODI
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 Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Typical Clean Water Flow Rates - Opticap® XLT Sterile and Gamma-Compatible Capsules Overview

Typical
Typical Clean
Clean Water
Water Flow
Flow Rates
Rates Selection & Applications Guide
ow Rates Opticap® XLT 10 Capsules Formats
Opticap
Opticap®
Opticap®XLT
XLT
®
XLT 10 Filters
Capsule
Capsule Capsules
Filters — — 0.22 μm Hydrophilic Opticap® XLT 20 Capsules —
Opticap®
Opticap®
0.1 μm XLT
XLT10
10Capsule
CapsuleFilters
Durapore Filters
® ——
Membrane Opticap®
Opticap®
DuraporeXLT
XLT1010
® Capsule
CapsuleFilters
MembraneFilters—— Opticap®
0.1 μmXLT 20 Capsule Filters
Durapore ® —
Membrane Opticap® XLT 20 Capsule Filters — OptiScale® Capsules
Opticap®
0.1
0.1µm XLT 10 Capsule
µmHydrophilic
Hydrophilic FiltersMembrane
Durapore®
Durapore® —
Membrane 0.22
0.22µm
µmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane 0.1 µm Hydrophilic Durapore® Membrane 0.22 µm Hydrophilic Durapore® Membrane
rane 0.22 µm Hydrophilic Durapore® Membrane Opticap® XLT 20 Capsule Filters ——
Opticap® XLT 20 Capsule Filters Opticap® XLT 20 Capsule Filters ——
Opticap® XLT 20 Capsule Filters Cartridge Filters
0.1 µm Hydrophilic Durapore® Membrane
0.1 µm Hydrophilic Durapore® Membrane 0.22µm
0.22 µmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane
Cartridges
Optiseal® Cartridges
Millidisk® Cartridges

Capsule Filters
Opticap® XL and XLT Capsules

Filters for Final Filtration

Opticap® XLT 20 Capsules Opticap
Opticap® ®
XLT XLT
30 30 Capsules
Capsule Filters — Opticap® XLT 30 Capsule Filters — Millipak® Final Fill Capsules
— 0.22
Opticap®
Opticap® μm
XLT
XLT20 Hydrophilic
20Capsule
CapsuleFilters
Filters —— Opticap
Opticap®
Opticap®XLT
XLT XLT
®20
20 30Filters
Capsule
Capsule Capsules
Filters —— — 0.1 µm Hydrophilic
— 0.22 Durapore® Membrane
μm Hydrophilic 0.22 µm Hydrophilic Durapore® Membrane
Opticap®
0.1
0.1µm XLT 20
® Capsule
µmHydrophilic
Hydrophilic FiltersMembrane
Durapore®
Durapore® —
Membrane Opticap®
Opticap®
0.22
0.22µm
µm XLT30
XLT 30Capsule
Capsule
Hydrophilic
Hydrophilic FiltersMembrane
Filters
Durapore®
Durapore® ——
Membrane Opticap®XLT
Opticap® XLT30
30 CapsuleFilters
® Capsule Filters —— M
 illidisk
Opticap® XLT Capsule ®
Barrier
Legends Refer to Cartridges
rane
Durapore Membrane
0.22 µm Hydrophilic Durapore® Membrane
0.1
0.1µm
μm Durapore
µmHydrophilic
®
HydrophilicDurapore®
Membrane
Durapore®Membrane
Membrane
Durapore
0.22µm
Membrane
µmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane Opticap® XLT Capsule Legends
0.1 0.22 Connection Type and Millipak® Barrier Capsules
Refer
Opticap®toXLT
Connection
CapsuleLegends Type
Legends Refertoto
Opticap® XLT Capsule Refer
Connection
Connection Type (1½ in.) Sanitary TT = 38 mm (1½ in.) Sanitary
TT = 38 Type
mm
Flange Inlet and Outlet
TTTT==38 Flange
38mmmm(1½ (1½in.)Inlet and Outlet
in.)Sanitary
Sanitary TH = 38 mm Durapore
(1½ in.) Sanitary® 0.1 μm & 0.22 μm
TH =  38 Inlet
Flange
Flange mm
Inletand (1½
and in.) Sanitary
Outlet
Outlet Flange Inlet and 16 mm (5/8 in.)
THTH==3838Flange
mm(1½
mm (1½Inlet and 16 mm
in.)Sanitary
in.) Sanitary Durapore
Hose Barb Outlet ®
0.45 μm
(5/8 Inlet
Flange
Flange in.)
Inletand Hose
and16 Barb
mm(5(/58/Outlet
16mm in.)
8in.)
HH = 16 mm (5/8 in.) Hose Barb Inlet and Outlet
HH =  Hose
Hose Barb
16Barb
mmOutlet Outlet
(5/8 in.) Hose Barb Durapore ®
5.0 μm
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet
HHHH==1616Inlet
mm(5(and
mm in.)Outlet
/58/8in.) HoseBarb
Hose BarbInlet
Inletand
andOutlet
Outlet
BB
BBBB=== 
2525
25 mmmm
mm (1(1in.) (1
in.) in.)
Hose
Hose Hose
Barb
Barb Inlet
Inlet Barb
andandOutlet
Outlet
Multimedia Durapore®
Inlet and Outlet Charged Durapore® 0.22 μm
Cartridge Filters Multilayer Durapore®
Cartridge Filters — Cartridge Filters —
Opticap®
Opticap®XLT
XLT30
30Capsule
CapsuleFilters
Filters —— Opticap®
Opticap®
Cartridge
Cartridge XLT
XLT30
30Capsule
CapsuleFilters
Filters
Filters Filters —— 0.1 µm Hydrophilic Durapore® Membrane 0.22 µm Hydrophilic Durapore® Membrane
Durapore® CBR 0.1 μm &
Opticap®
0.1
0.1µm XLT 30 Capsule
µmHydrophilic
Hydrophilic FiltersMembrane
Durapore®
Durapore® —
Membrane 0.22
0.22µm
µmHydrophilic
Hydrophilic
Cartridge
Cartridge Filters—— Durapore®
Filters Durapore®Membrane
Membrane CartridgeFilters
Cartridge Filters—— 0.2 μm
rane 0.22 µm Hydrophilic Durapore® Membrane
0.1µm
0.1 µmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane Opticap®
Opticap®
0.22
0.22 µm XLT
XLTCapsule
Capsule
µmHydrophilic
Hydrophilic Legends
LegendsRefer
Durapore®
Durapore® Refertoto
Membrane
Membrane
Opticap® XLT Capsule Legends Refer to Connection
ConnectionType
Type Hydrophobic Durapore®
Connection Type
TTTT==38
38mmmm(1½(1½in.)in.)Sanitary
Sanitary 0.22 μm
TT = 38 mm (1½ in.) Sanitary Flange
FlangeInlet
InletandandOutlet
Outlet
Flange Inlet and Outlet Hydrophobic-hydrophilic
THTH==3838mm
mm(1½ (1½in.)in.)Sanitary
Sanitary
TH = 38 mm (1½ in.) Sanitary Flange
FlangeInlet
Inletandand16 mm(5(/58/8in.)
16mm in.) Durapore® 0.22 μm
Flange Inlet and 16 mm (5/8 in.) Hose
HoseBarb
BarbOutlet
Outlet
Hose Barb Outlet
HHHH==1616mmmm(5(/58/8in.)
in.)Hose
HoseBarb
BarbInlet
Inletand
andOutlet
Outlet
HH = 16 mm (5/8 in.) Hose Barb Inlet and Outlet Contact Information
BBBB==2525mm
mm(1(1in.)in.)Hose
HoseBarb
BarbInlet
Inletand andOutlet
Outlet
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet

9
Cartridge
CartridgeFilters
Filters
Cartridge
CartridgeFilters
Filters—— Cartridge
CartridgeFilters
Filters—— 99
Cartridge
0.1
0.1µm Filters — Durapore®
µmHydrophilic
Hydrophilic Durapore®Membrane
Membrane 0.22
0.22µmµmHydrophilic
HydrophilicDurapore®
Durapore®Membrane
Membrane
rane 0.22 µm Hydrophilic Durapore® Membrane
26
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide
Typical Clean Water Flow Rates
Typical Clean
Typical Water
Typical
Typical
Clean Water Flow
Clean Rates
Water
Clean
Flow Flow
Water
Rates –Rates
Flow Millipak
Rates
®
Final Fill Capsule Filters Overview
Selection & Applications Guide
Millipak® FinalMillipak Final Fill 20/40/60 Capsule Filters with 0.1 µm Millipak ®
Final Fill 100/200 Capsule Filters with 0.1 µm
® ®
Fill 20/40/60 Capsule Filters — 0.1 μm
Hydrophilic Durapore® Membrane
Millipak Final Fill 100/200 Capsule Filters — 0.1 μm
Hydrophilic Durapore® Membrane Formats
Durapore® Membrane
Millipak
20
Millipak
Final Fill40
H, Typical 20/40/60 ®
Final
Millipak
H, Typical
® Fill 20/40/60 Capsule Filters with 0.1 µm
Final60
Capsule Fill 20/40/60
Filters
H/T, with 0.1Capsule
Typical µm Filters with 0.1 µm
®
Durapore 100 Membrane
®
Millipak Final Millipak
Fill 100/200
B/T, Typical
®
Final
Millipak ® Fill 100/200 Capsule Filters with 0.1 µm
CapsuleFinal
200
®
FillTypical
Filters
B/T, 100/200
with 0.1 Capsule
µm Filters with 0.1 µm
Hydrophilic Durapore Membrane Hydrophilic Durapore Membrane
OptiScale® Capsules
® ®
50 Hydrophilic Durapore ®
Hydrophilic
Membrane Durapore ®
Membrane 50 Hydrophilic Durapore ®
Hydrophilic
Membrane Durapore ®
Membrane
20 H,20
Typical 40
60 H, Typical 60 H/T, Typical 100200
B/T, Typical 200 B/T,
200 Typical
(psid) (psid)

(psid) (psid)
20 H, Typical 40 H, Typical H/T,
40 Typical
H, Typical 60 H/T, Typical 100 B/T, Typical B/T,
100 Typical
B/T, Typical B/T, Typical
50 50 50 50 50 50
40 40 Cartridge Filters
Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

Pressure

Pressure
40
30 40 40 40
30 40 40
Cartridges
Pressure

Pressure
30
20 30 30 30
20 30 30
Differential

Differential
Optiseal® Cartridges
20 20 20 20 20 20
Differential

Differential
10 10
Millidisk® Cartridges
10
0 10 10 10
0 10 10
0 0.5 1 1.5 2 0 2 4 6 8 10 12
0 0 0 0
0 0 0
0.5
Flow Rate (L/min)
0.5
1 0.5 1 1
1.5 1.5 1.5
2 20 0 2 2 0 0 04 Flow Rate (L/min)
2 26 4 48 6 610 8 812 10 10 12 12 Capsule Filters
Flow Rate (L/min) Flow Flow
Rate (L/min)
Rate (L/min) Flow Rate (L/min) Flow Flow
Rate (L/min)
Rate (L/min)
Opticap® XL and XLT Capsules
Millipak® Final Fill 100/200 Capsule Filters with 0.22 µm
Millipak® Final Fill 20/40/60 Capsule Filters — 0.22 μm Millipak® Hydrophilic
Final Fill 100/200
Durapore ®
MembraneCapsule Filters — 0.22 μm
Durapore® Membrane
Millipak® Final Fill 20/40/60 Capsule Filters with 0.22 µm Durapore
Millipak Final Membrane
® Fill 100/200
Millipak ®
Final
® Fill
Capsule
Millipak 100/200
Filters
Final®
withCapsuleµmFilters
0.22Capsule
Fill 100/200 with with
Filters 0.22 0.22
µm µm Filters for Final Filtration
Hydrophilic Durapore® Membrane 100 B, TypicalHydrophilic
100 K/L, Hydrophilic
Durapore
Typical®
MembraneDurapore
Hydrophilic
100 F/T,
®
Membrane
Durapore
Typical ®
Membrane
Millipak ®
Final
20 All Types, Typical Millipak
40 Final
Fill 20/40/60 ®
All
® Fill Filters
Final20/40/60
Capsule
Millipak Types, withCapsule
0.22
Fill 20/40/60
Typical AllFilters
µm
Capsule
60 with
Filters
Types, 0.22 0.22
with
Typical µm µm 200 B, Typical 200 B,
100 K/L, Typical
Typical 200 F/T,Typical
Typical Millipak® Final Fill Capsules
50 Hydrophilic Durapore Hydrophilic
®
Membrane Durapore
Hydrophilic ®
Membrane
Durapore ®
Membrane 50 100 B, Typical 100 K/L,
100 B, Typical 100
Typical 100K/L,
F/T,
100 K/L, Typical 100 F/T,
Typical 100 Typical
F/T, Typical
20 All Types, Typical 20 All20
Types, Typical Typical 40 All40
Types, Typical Typical 60 All60
Types, Typical B,200
Typical
B, Typical 200
200K/L,
200TypicalTypical 200 F/T,
200 Typical M
 illidisk® Barrier Cartridges
(psid) (psid)

(psid) (psid)
40
AllAll Types,
Types, Typical 60
All All Types,
Types, Typical All Types, Typical 200 B, Typical 200 K/L, Typical F/T, Typical
K/L, F/T, Typical
50
40 50 50 50
40 50 50
and Millipak® Barrier Capsules
Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

Pressure

Pressure
40
30 40 40 40
30 40 40
Pressure

Pressure
30
20 30 30 30
20 30 30
Differential

Differential

Durapore® 0.1 μm & 0.22 μm

20
10 20 20 20
10 20 20
Differential

Differential

10 10 10 10 10 10
Durapore® 0.45 μm
0 0
0 0.5 1 1.5 2 2.5 3 0 2 4 6 8 10 12 14 16 18 20
0 0 0 0 0 Durapore® 5.0 μm
0 0.5 0 01
Flow Rate (L/min)
0.5 0.5
1.5 1 12 1.5 1.5
2.5 2 23 2.5 2.5 3 03 2 4 0 060 2 Flow
82 4Rate
104(L/min)
6 126 8 148 10 161012 181214 201416 1618 1820 20
Flow Rate (L/min) Flow Flow
Rate (L/min)
Rate (L/min) Flow Rate (L/min) Flow Flow
Rate (L/min)
Rate (L/min)
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Millipak® Final Fill 20/40/60 Capsule Filters with 0.45 µm Millipak® Final Fill 100/200 Capsule Filters with 0.45 µm

Millipak ®
Hydrophilic Durapore® Membrane
Millipak
Final Fill 40
20/40/60 ®
Final
® Fill Filters
Capsule 20/40/60withCapsule
0.45 Filters
µm with with
0.45 0.45
µm µm Millipak ®
Hydrophilic Durapore® Membrane
Millipak
Final Fill100
100/200 ®
Final
® Fill
Capsule 100/200
Filters withCapsuleµmFilters
0.45Capsule with with
0.45 0.45
µm µm
Durapore® CBR 0.1 μm &
20 H, Typical H, Millipak
Typical Final60Fill
H, 20/40/60
Typical Capsule
60 T, Filters
Typical 100 B, Typical T, Millipak
Typical Final Fill
200 B,100/200
Typical Filters
200 T, Typical
50 Hydrophilic Durapore Hydrophilic
®
Membrane Durapore
Hydrophilic ®
Membrane
Durapore ®
Membrane 50 Hydrophilic Durapore Hydrophilic
®
Membrane Durapore
Hydrophilic ®
Membrane
Durapore ®
Membrane 0.2 μm
(psid) (psid)

(psid) (psid)

20 H, Typical 20 H, 20
40 Typical
H, Typical 40
60 H,40
Typical
H, Typical 60 T,
H,60Typical
Typical
H, Typical 60 T, 60
Typical
T, Typical 100 B, Typical 100 T,
100 B,100
Typical
Typical 100 B,
B, Typical 200 T,100
Typical
Typical 200 T,
T, Typical 200 B,200
Typical
B, Typical 200 T,200
Typical Typical
T, Typical
50
40 50 50 50
40 50 50 Hydrophobic Durapore®
Differential Pressure (psid)

Differential Pressure (psid)

0.22 μm
Differential Pressure (psid)

Differential Pressure (psid)

Pressure

Pressure

40
30 40 40 40
30 40 40
Pressure

Pressure

30
20 30 30 30
20 30 30 Hydrophobic-hydrophilic
Differential

Differential

20
10 20 20 20
10 20 20 Durapore® 0.22 μm
Differential

Differential

10
0 10 10 10
0 10 10
0 2 4 6 8 10 0 5 10 15 20 25 30
0 0 0 Flow Rate (L/min) 0 0 0 Flow Rate (L/min) Contact Information
0 2 0 0 4 2 2 6 4 4 8 6 6 10 8 8 10 0 10 5 0 010 5 515 20
10 10 25
15 15 30
20 20 25 25 30 30
Flow Rate (L/min) Flow Flow
Rate (L/min)
Rate (L/min) Flow Rate (L/min) Flow Flow
Rate (L/min)
Rate (L/min)

Legend
B = 13 mm (½
Legend in.)
Legend stepped hose barb inlet and outlet
Legend
Millipak® Final Fill 60/200 Capsule Filters with 5.0 µm
Hydrophilic Durapore® Membrane
C = 13
B 19 mm (½
(¾B in.)
=B13=sanitary
stepped
mm
13 mm flange
(½hose inlet
barb
in.) in.)
(½ stepped and
inlet and
hose
stepped hoseoutlet
barb inletinlet
barb andand
outlet
outlet
60Millipak
H, TypicalFinal Fill
®
6060/200
MillipakCapsule
®
Final Filters
® Fill 60/200with 5.0Capsule
µmFilters
Capsule with with
5.0 µm 6 mm (¼ in.) hose barb outlet
Millipak
T, Typical Final
200Fill 60/200
B, Typical Filters
200 T, Typical 5.0 µm C = 19 mm (¾ C in.)
=C19=sanitary
mm
19 mm(¾flange inlet
in.) in.)
(¾ sanitary and
flange
sanitary inletinlet
flange andand
5
27
Hydrophilic Durapore Membrane
Hydrophilic
®
Durapore
Hydrophilic ®
Membrane
Durapore ®
Membrane
F = 19 6 mmmm(¼
(¾in.)
in.)6sanitary
hose
mm (¼ flange
barb
6 mm (¼outlet
in.) inlet
hose
in.) and
barb
hose outlet
outlet
barb outlet
(psid) (psid)

60 H, Typical 60 T, Typical
H,60
Typical
H, Typical 200T,B,60
60 Typical
Typical
T, Typical T,200
200 B, Typical
Typical
B, Typical 200 T,200
Typical
T, Typical
5
4 5 5 H= = 196 mm
F mm(¼
(¾Fin.)
in.)stepped
=F19sanitary
= mm (¾
19 mm hose
in.)barb
flange
(¾ inlet
inlet
sanitary
in.) and and
flange
sanitary outlet
outletinletinlet
flange andand
outlet
outlet
ssure (psid)
Pressure

ssure (psid)

4
3 4 4 K = 19mm
H (¾Hin.)
6 mm (¼ in.)
=H6 sanitary
stepped
=mm
6 mm flange
(¼hose inlett
barb
in.) in.)
(¼ stepped and
inlet
stepped and
hose outlet
barb
hose inletinlet
barb andand
outlet
outlet
13 mm (½ in.) hose barb outlet
ssure

3
2 3 3 K = 19mm (¾Kin.) sanitary
=K19mm
= 19mm(¾flange
(¾ inlett
in.) in.)
sanitary and
flange
sanitary inlett
flange andand
inlett
ial
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
OptiScale® Capsules
OptiScale® Capsules
Cartridge Filters
S V A Cartridges
Optiseal® Cartridges
Membrane Type May be Disc Size Quantity per pkg. Millidisk® Cartridges
Autoclaved
V = Durapore®
25 = 25 mm 3 = 3/pk
47 = 47 mm 6 = 6/pk
Capsule Filters
OptiScale® Pore Size
Connection Type Opticap® XL and XLT Capsules
Capsule Filter
VL = 0.1 μm
HH = 6 mm (¼ in.) Hose Barb Inlet and Outlet
GL = 0.22 μm
FF = 19 mm (¾ in.) Sanitary Flange Inlet and Outlet Filters for Final Filtration
FH = 19 mm (¾ in.) Sanitary Flange Inlet and
6 mm (¼ in.) Hose Barb Outlet Millipak® Final Fill Capsules
NB = Female Luer-Lok™ Inlet/Male Luer Slip Outlet M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Cartridge Filters
Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
C V
Durapore® 5.0 μm
Multimedia Durapore®
Media Type Cartridge Code Packaging Code
Charged Durapore® 0.22 μm
V = Durapore® 0 = (2-222) O-ring S01 = 1/pk (5-inch element only)
5 = (2-222) O-ring with spear TP3 = 3/pk (all other elements) Multilayer Durapore®
7 = (2-226) O-ring with locking Durapore® CBR 0.1 μm &
Cartridge Pore Size tab and spear
VL = 0.1 μm
0.2 μm
GL = 0.22 μm Hydrophobic Durapore®
Cartridge Length
0.22 μm
1= 10-inch
2= 20-inch Hydrophobic-hydrophilic
3= 30-inch Durapore® 0.22 μm
5= 5-inch (Code 0
and Code 7 only)
Contact Information

28
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Optiseal® Cartridges
OptiScale® Capsules
Cartridge Filters
L A 0 4 T P 6 Cartridges
Optiseal® Cartridges
Cartridge Pore Size Cartridge Length Quantity per pkg. Millidisk® Cartridges
Filter
VL = 0.1 μm 4 = 4-inch 6 = 6/pk
GL = 0.22 μm
Capsule Filters
Media Type Cartridge Code Connection Type
Opticap® XL and XLT Capsules
A=D
 urapore® 0 = (2-222) O-ring
membrane
Filters for Final Filtration
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
Millidisk® Cartridges and Millipak® Barrier Capsules

M C 0 3 Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Millidisk® Cartridges Pore Size Millidisk® Stack Size Connection Type Quantity per pkg. Durapore® 5.0 μm
VL = 0.1 μm 40S = 40-stack 3 = 3/pk Multimedia Durapore®
GL = 0.22 μm 30S = 30-stack
Charged Durapore® 0.22 μm
20S = 20-stack
10S = 10-stack Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

29
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Opticap® XL Autoclavable Capsule Filters
OptiScale® Capsules
Cartridge Filters
K V A Cartridges
Optiseal® Cartridges
Media Type May be Disc Size Quantity per pkg. Millidisk® Cartridges
Autoclaved
V = Durapore ®
02 = Opticap
®
XL 2 1=1  /pk (Opticap XL 5
®

04 = Opticap® XL 4 and 10 filters only)

3 = 3/pk (Opticap® XL 2 Capsule Filters
05 = Opticap® XL 5
Opticap® XL Pore Size and 4 filters only)
10 = Opticap® XL 10 Opticap® XL and XLT Capsules
Capsule Filter
VL = 0.1 μm
GL = 0.22 μm
Connection Type Filters for Final Filtration
TT = 38 mm (1 ½ in.) Sanitary Flange Inlet and Outlet Millipak® Final Fill Capsules
FF = 19 mm (¾ in.) Sanitary Flange Inlet and Outlet
HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet
M
 illidisk® Barrier Cartridges
TH = 38 mm (1 ½ in.) Sanitary Flange Inlet and 14 mm (9/16 in.) and Millipak® Barrier Capsules
Hose Barb Outlet
FH = 19 mm (¾ in.) Sanitary Flange Inlet and 14 mm (9/16 in.)
Hose Barb Outlet (Opticap® XL 2 and 4 filters only) Durapore® 0.1 μm & 0.22 μm
NN = 6 mm (¼ in.) NPT Inlet and Outlet (Opticap® XL 2 and 4
Durapore® 0.45 μm
filters only, 0.22 µm only)
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Opticap® XL Sterile and Gamma-Compatible Capsule Filters
Multilayer Durapore®
Durapore® CBR 0.1 μm &
K V 0.2 μm
Hydrophobic Durapore®
0.22 μm
Membrane Type Sterilization Capsule Sizes Quantity per pkg.
V = Durapore® G=G  amma- 04 = Opticap® XL 4 1 = 1/pk Hydrophobic-hydrophilic
Compatible 10 = Opticap® XL 10 3 = 3/pk Durapore® 0.22 μm
S = Sterile
Opticap® XL Pore Size
Capsule Filter Connection Type
VL = 0.1 μm Contact Information
TT = 38 mm (1 1/2 in.) Sanitary Flange Inlet and Outlet
GL = 0.22 μm
FF = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet
HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet
TH = 3 8 mm (1 1/2 in.) Sanitary Flange Inlet and
14 mm (9/16 in.) Hose Barb Outlet
FH = 19 mm (3/4 in.) Sanitary Flange Inlet and
14 mm (9/16 in.) Hose Barb Outlet
30
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Opticap® XLT Autoclavable Capsule Filters
OptiScale® Capsules
Cartridge Filters
K V A 1 Cartridges
Optiseal® Cartridges
Media Type May be Gauge Port Quantity per pkg. Millidisk® Cartridges
Autoclaved
V = Durapore® T = Without Gauge Port 1 = 1/pk
Z = With Gauge Port
Capsule Filters
Opticap® XLT Pore Size
Capsule Filter
Opticap® XL and XLT Capsules
VL = 0.1 μm
GL = 0.22 μm
Capsule Size Filters for Final Filtration
Connection Type
1 = Opticap® XLT 10
TT = 38 mm (1 ½ in.) Sanitary Flange Inlet and Outlet Millipak® Final Fill Capsules
2 = Opticap® XLT 20
HH = 16 mm (5⁄8 in.) Hose Barb Inlet and Outlet M
 illidisk® Barrier Cartridges
3 = Opticap® XLT 30
TH = 38 mm (1 ½ in.) Sanitary Flange Inlet and
and Millipak® Barrier Capsules
16 mm (5⁄8 in.) Hose Barb Outlet
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Opticap® XLT Sterile and Gamma-Compatible Capsule Filters Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
K V T 1
Multilayer Durapore®
Durapore® CBR 0.1 μm &
Membrane Type Sterilization Gauge Port Quantity per pkg. 0.2 μm
V = Durapore® G=G  amma- T=W
 ithout 1 = 1/pk
Compatible gauge port
Hydrophobic Durapore®
S = Sterile 0.22 μm
Hydrophobic-hydrophilic
Opticap® XLT Pore Size Capsule Sizes Connection Type
Capsule Filter Durapore® 0.22 μm
VL = 0.1 μm 1 = Opticap® XLT 10 TT = 3
 8 mm (11⁄2 in.) Sanitary Flange Inlet and Outlet
GL = 0.22 μm 2 = Opticap® XLT 20 HH = 16 mm (5⁄8 in.) Hose Barb Inlet and Outlet
3 = Opticap® XLT 30 TH = 3
 8 mm (11⁄2 in.) Sanitary Flange Inlet and Contact Information
16 mm (5⁄8 in.) Hose Barb Outlet
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet

Accessory
Description Qty/Pk Cat. No.
Standard Opticap® XLT Capsule Filter Stand 1/pk XLTSTAND1
31
Filters Containing Durapore® 0.1 μm and 0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Millipak® Final Fill Capsule Filters
OptiScale® Capsules
Cartridge Filters
M F 3 Cartridges
Optiseal® Cartridges
Millipak Final
®
Membrane Pore Size Quantity per pkg. Millidisk® Cartridges
Fill Filter
VL = Durapore 0.1 μm
® 3 = 3/pk
GL = Durapore® 0.22 μm
Capsule Filters
Millipak Final Fill Filter Series
®
Opticap® XL and XLT Capsules
02G = 20, Non-sterilized
02S = 20, Sterilized by Gamma Radiation Connection Type
Filters for Final Filtration
04G = 40, Non-sterilized Millipak® Final Fill 20, 40, 60
04S = 40, Sterilized by Gamma Radiation C* = 19 mm (3/4 in.) Sanitary Flange Inlet and 6 mm (1/4 in.) Hose Barb Outlet Millipak® Final Fill Capsules
06G = 60, Non-sterilized H = 6 mm (1/4 in.) Stepped Hose Barb Inlet and Outlet
M
 illidisk® Barrier Cartridges
06S = 60, Sterilized by Gamma Radiation Millipak® Final Fill 60, 100, 200 and Millipak® Barrier Capsules
10G = 100, Non-sterilized L* = 38 mm (1½ in.) Sanitary Flange Inlet and 13 mm (1/2 in.) Stepped Hose Barb Outlet
10S = 100, Sterilized by Gamma Radiation T = 38 mm (1½ in.) Sanitary Flange Inlet and Outlet
20G = 200, Non-sterilized Millipak® Final Fill 100, 200 Durapore® 0.1 μm & 0.22 μm
20S = 200, Sterilized by Gamma Radiation B = 13 mm (1/2 in.) Stepped Hose Barb Inlet and Outlet
K* = 19 mm (3/4 in.) Sanitary Flange Inlet and 13 mm (1/2 in.) Hose Barb Outlet
Durapore® 0.45 μm
Millipak® Final Fill 20, 40, 60, 100, 200 Durapore® 5.0 μm
F = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet Multimedia Durapore®
* available with 0.22 μm Membrane only Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

32
Filters Containing Durapore 0.45 μm Membrane ® Durapore® Family Guide

Overview
For bioburden reduction and particulate removal
Selection & Applications Guide
Formats
OptiScale® Capsules
Filters containing Durapore® 0.45 μm
Cartridge Filters
hydrophilic polyvinylidene fluoride
Cartridges
(PVDF) membrane can extend the life of
sterilizing filters by removing particles and Optiseal® Cartridges
microorganisms from liquid streams. These Millidisk® Cartridges
filters are ideally suited for large volume
parenteral or ophthalmics manufacturing where Capsule Filters
protein binding must be minimized. Opticap® XL and XLT Capsules

Filters containing Durapore® 0.45 μm membrane Filters for Final Filtration

are available with or without an integrated Millipak® Final Fill Capsules
prefilter, providing opportunities for process
M
 illidisk® Barrier Cartridges
efficiency with prefiltration and bioburden and Millipak® Barrier Capsules
reduction in a single filter.
Durapore® 0.1 μm & 0.22 μm
Benefits Filter Formats
Durapore® 0.45 μm
• Ideal for bioburden reduction before final sterilization • OptiScale® capsules
Durapore® 5.0 μm
• Low protein binding membrane yields high protein • Cartridge filters
Multimedia Durapore®
recovery with minimal product loss
• Millidisk cartridges
®
Charged Durapore® 0.22 μm
• Broad chemical compatibility, low extractables
• Opticap XL and XLT capsules
®
Multilayer Durapore®
• For filtration processes requiring high flow rates and
• Millipak Final Fill capsules
®
Durapore® CBR 0.1 μm &
throughputs
0.2 μm
Hydrophobic Durapore®
Membrane Types 0.22 μm
Hydrophobic-hydrophilic
• 0.45 μm Durapore® membrane with prefilter
Durapore® 0.22 μm
• 0.45 μm Durapore® membrane without prefilter
Contact Information

33
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

OptiScale® Capsule and Cartridge Filter Specifications Overview

Selection & Applications Guide
Description OptiScale® 25 Capsule OptiScale® 47 Capsule Cartridge (per 10-inch)
Formats
Nominal Dimensions
Maximum length: 39 mm (1.52 in.) with female 82 mm (3.24 in.) with flange inlet/ — OptiScale® Capsules
Luer-Lok™ inlet/male luer slip hose barb outlet
outlet 74 mm (2.91 in.) with flange inlet/ Cartridge Filters
flange outlet
94 mm (3.70 in.) with hose barb Cartridges
inlet/hose barb outlet Optiseal® Cartridges
Body diameter: 31 mm (1.21 in.) 69 mm (2.75 in.) 6.9 cm (2.7 in.)
Weight: 0.19 oz (5.5 g) 2.3 oz (67 g) — Millidisk® Cartridges
Filtration Area 3.5 cm2 17.7 cm2 0.69 m2 (7.4 ft2)
Materials of Construction Capsule Filters
Filter membrane: Hydrophilic PVDF Hydrophilic PVDF Hydrophilic PVDF Opticap® XL and XLT Capsules
Prefilter media: — — Mixed esters of cellulose
Film edge: — — Polypropylene
Structural components: Polypropylene Polycarbonate Polypropylene Filters for Final Filtration
Supports: Polypropylene Polypropylene Polypropylene
Vent cap: Polypropylene Polyvinylidene fluoride (PVDF) — Millipak® Final Fill Capsules
Internal seal rings: — Fluoroelatomers Silicone M
 illidisk® Barrier Cartridges
Housing Vent Capped vent with female Luer Adjustable vent with male luer and — and Millipak® Barrier Capsules
connections on inlet side of device. female Luer-Lok™ connections on
inlet side of device.
Maximum Inlet Pressure 4.1 bar (60 psi) at 25 °C 5.5 bar (80 psi) at 25 °C — Durapore® 0.1 μm & 0.22 μm
Maximum Differential Pressure Durapore® 0.45 μm
Forward: 4.1 bar (60 psi) at 25 °C 5.5 bar (80 psig) at 25 °C 5.5 bar (80 psid) at 25 °C
— — 1.8 bar (25 psid) at 80 °C Durapore® 5.0 μm
— — 345 mbar (5 psid) at 135 °C
Multimedia Durapore®
Reverse: 0 bar (0 psi) 0.7 bar (10 psig) at 25 °C 3.5 bar (50 psid) at 25 °C,
intermittent Charged Durapore® 0.22 μm
Bubble Point at 23 °C — — ≥ 1790 mbar (26 psig) air Multilayer Durapore®
with water
Durapore® CBR 0.1 μm &
Air Diffusion — — Through a water wet membrane
at 23 °C at 1.5 bar (22 psi): 0.2 μm
≤ 15 cc/mm
Hydrophobic Durapore®
Total Organic Carbon (TOC)/ — — Autoclaved filter effluent meets the 0.22 μm
Conductivity WFI requirement of USP <643>,
for Total Organic Carbon and USP Hydrophobic-hydrophilic
<645> for Water Conductivity at Durapore® 0.22 μm
25 ºC after a WFI flush of 11.5 L
Oxidizable Substances — Meets the requirements of the USP Oxidizable Substance Test for sterile
purified water after a water flush of: Contact Information
100 mL 1000 mL
Bacterial Endotoxin Aqueous extraction contains < 0.25 — Aqueous extraction contains < 0.5
EU/mL as determined by the Limulus EU/mL as determined by the Limulus
Amebocyte Lysate (LAL) Test. This Amebocyte Lysate (LAL) Test. This
meets the requirements of USP <85>. meets the requirements of USP <85>.

34
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

OptiScale® Capsule and Cartridge Filter Specifications (continued) Overview

Selection & Applications Guide
Description OptiScale® 25 Capsule OptiScale® 47 Capsule Cartridge (per 10-inch)
Formats
Sterilization May be autoclaved for 1 cycle of May be autoclaved for 3 cycles of With prefilter:
60 minutes at 123 °C. 60 minutes at 123 °C. May be autoclaved for 10 cycles OptiScale® Capsules
of 60 minutes at 121 °C; steam
sterilized for 10 cycles of 30 minutes Cartridge Filters
at 121 °C; or hot water sanitized for
30 cycles of 30 minutes at 80 °C. Cartridges
Without prefilter: Optiseal® Cartridges
May be autoclaved for 30 cycles
of 60 minutes at 126 °C; steam Millidisk® Cartridges
sterilized for 30 cycles of 30 minutes
at 135 °C; or hot water sanitized for
30 cycles of 30 minutes at 80 °C. Capsule Filters
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter; defined in 21 CFR 210.3 (b) (6). Opticap® XL and XLT Capsules
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on Filters for Final Filtration
information provided by raw material suppliers.
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
Millidisk® Cartridge Filter Specifications and Millipak® Barrier Capsules

Description Millidisk® 10 Millidisk® 20 Millidisk® 30 Millidisk® 40

Durapore® 0.1 μm & 0.22 μm
Filtration Area 500 cm (0.54 ft )
2 2
1000 cm (1.08 ft )
2 2
1500 cm (1.61 ft )
2 2
2000 cm2 (2.15 ft2)
Durapore® 0.45 μm
Materials of Construction
Filter membrane: Durapore® PVDF membrane Durapore® 5.0 μm
Structural components: Polysulfone
O-rings: Silicone
Multimedia Durapore®
Maximum Differential Pressure Charged Durapore® 0.22 μm
Forward: 4.1 bar (60 psid) at 25 °C Multilayer Durapore®
1.7 bar (25 psid) at 80 °C
345 mbar (5 psid) at 123 °C Durapore® CBR 0.1 μm &
Reverse: 690 mbar (10 psid) at 25 °C 0.2 μm
Bubble Point at 23 °C ≥ 1790 mbar (26.0 psig) in water
Hydrophobic Durapore®
Connections Millidisk® filters incorporate a double 2–118 (silicone) O-ring seal and are used with Millidisk® or Millidisk®/ 0.22 μm
Milligard® stainless steel housings.
Hydrophobic-hydrophilic
Gravimetric Extractables Through a water wet membrane at an ambient temperature of 1.5 bar (22 psi):
2.5 mg/unit 5 mg/unit 7.5 mg/unit 10 mg/unit
Durapore® 0.22 μm
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for sterile purified water after steaming and water flush
of 200 mL.
Contact Information
Bacterial Endotoxin An aqueous extraction from a Millidisk® filter contains < 0.5 EU/mL bacterial endotoxin as determined by the
Limulus Amebocyte Lysate (LAL) test. This meets the requirements of USP <85>.

35
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Millidisk® Cartridge Capsule Filter Specifications (continued) Overview

Description Millidisk® 10 Millidisk® 20 Millidisk® 30 Millidisk® 40

Selection & Applications Guide
Sterilization Formats
Autoclave: 126 °C, 60 minutes, up to 5 times OptiScale® Capsules
Steam-in-place: 135 °C, 60 minutes, up to 5 times
Cartridge Filters
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Cartridges
Optiseal® Cartridges
Opticap® XL Autoclavable Capsule Filter Specifications Millidisk® Cartridges

Description Opticap® XL 2 Opticap® XL 4 Opticap® XL 5 Opticap® XL 10

Capsule Filters
Nominal Dimensions
Maximum length: 14.2 cm (5.6 in.) 19.6 cm (7.7 in.) 21.6 cm (8.5 in.) 33.5 cm (13.2 in.)
Opticap® XL and XLT Capsules
Body diameter: 8.4 cm (3.3 in.) 8.4 cm (3.3 in.) 10.7 cm (4.2 in.) 10.7 cm (4.2 in.)
Filtration Area 0.09 m2 (0.93 ft2) 0.19 m2 (2.09 ft2) 0.35 m2 (3.7 ft2) 0.69 m2 (7.4 ft2) Filters for Final Filtration
Materials of Construction Millipak® Final Fill Capsules
Filter membrane: Hydrophilic PVDF
Prefilter Media: Mixed esters of cellulose
M
 illidisk® Barrier Cartridges
Film edge: ­ – and Millipak® Barrier Capsules
Supports: Polypropylene
Structural components*: Polypropylene
Vent O-rings: Silicone Durapore® 0.1 μm & 0.22 μm
Vent/Drain /4 in. hose barb with double O-ring seal; connects to 1/8 in. tubing
1
Durapore® 0.45 μm
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C Durapore® 5.0 μm
2.8 bar (40 psi) at 60 °C
1.0 bar (15 psi) at 80 °C Multimedia Durapore®
Maximum Differential Pressure Charged Durapore® 0.22 μm
Forward: 5.5 bar (80 psid) at 25 °C (with prefilter)
1.0 bar (15 psid) at 80 °C (with prefilter) Multilayer Durapore®
3.4 bar (50 psid) at 25 °C (without prefilter)
Reverse: 3.4 bar (50 psid) at 25 °C, intermittent
Durapore® CBR 0.1 μm &
0.2 μm
Bubble Point at 23 °C ≥ 1930 mbar (28 psig) air with water
Hydrophobic Durapore®
Air Diffusion Through a water wet membrane at an ambient temperature of 1.5 bar (22 psi):
– ≤ 4.5 cc/min. ≤ 7.5 cc/min ≤ 15 cc/min
0.22 μm
Gravimetric Extractables After autoclaving and a 24 hour soak in ASTM Type 1 reagent grade water at controlled room temperature:
® Hydrophobic-hydrophilic
With prefilter – – – ≤ 50 mg Durapore® 0.22 μm
Without prefilter ≤ 10 mg ≤ 10 mg ≤ 15 mg ≤ 25 mg
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for sterile purified water after autoclaving and a water
flush of: Contact Information
500 mL 500 mL 500 mL 1000 mL
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This meets the
requirements of USP <85>.
Sterilization
With prefilter May be autoclaved for 3 cycles of 60 minutes at 121 °C. Cannot be steam sterilized in-line.
Without prefilter May be autoclaved for 3 cycles of 60 minutes at 126 °C. Cannot be steam sterilized in-line.
36
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Opticap® XL Autoclavable Capsule Filter Specifications (continued) Overview

Selection & Applications Guide
Description Opticap® XL 2 Opticap® XL 4 Opticap® XL 5 Opticap® XL 10
Formats
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
OptiScale® Capsules
information provided by raw material suppliers. Cartridge Filters
European Pressure This product complies with the European Pressure Equipment Directive, 2014/68/EU of 15 May 2014. This
product has been classified under article 4 § 3 of the Pressure Vessel Directive. It has been designed and
Cartridges
Equipment Directive
manufactured in accordance with sound engineering practice to ensure safe use. In compliance with Article 4 § Optiseal® Cartridges
3 of the Directive, 2014/68/EU, this product does not bear the CE mark.
Millidisk® Cartridges
*Cage, core, end caps, and capsule housing

Capsule Filters
Opticap® XL and XLT Sterile and Gamma-Compatible Capsule Filter Specifications
Opticap® XL and XLT Capsules
Description Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30
Nominal Dimensions Filters for Final Filtration
Maximum length: 33.5 cm (13.2 in.) 37.6 cm (14.8 in.) 62.5 cm (24.6 in.) 87.1 cm (34.3 in.)
Body diameter: 10.7 cm (4.2 in.) — — —
Millipak® Final Fill Capsules
Fitting to Fitting M
 illidisk® Barrier Cartridges
Sanitary flange to sanitary flange: 33.5 cm (13.2 in.) 15.2 cm (6.0 in.) 15.2 cm (6.0 in.) 15.2 cm (6.0 in.) and Millipak® Barrier Capsules
Sanitary flange to hose barb: 33.2 cm (13.1 in.) 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) 17.5 cm (6.9 in.)
Hose barb to hose barb: 33.2 cm (13.1 in.) 19.8 cm (7.8 in.) 19.8 cm (7.8 in.) 19.8 cm (7.8 in.)
Filtration Area 0.62 m2 (6.7 ft2) 0.62 m2 (6.7 ft2) 1.24 m2 (13.3 ft2) 1.86 m2 (20.0 ft2)
Durapore® 0.1 μm & 0.22 μm
Materials of Construction Durapore® 0.45 μm
Filter membrane: Hydrophilic Durapore PVDF membrane
®
Durapore® 5.0 μm
Film Edge: Polyethylene
Supports: Polyester/Polyethylene Multimedia Durapore®
Structural components*: Gamma-stable Polypropylene
Charged Durapore® 0.22 μm
Vent O-rings: Silicone
Vent/Drain /4 in. hose barb with double O-ring seal; connects to 1/8 in. tubing
1 Multilayer Durapore®
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C Durapore® CBR 0.1 μm &
2.8 bar (40 psi) at 60 °C 0.2 μm
1.0 bar (15 psi) at 80 °C
Hydrophobic Durapore®
Maximum Differential Pressure
0.22 μm
Forward: 4.1 bar (60 psid) at 4-40 ˚C
Reverse: 2.1 bar (30 psid) at 4-40 ˚C Hydrophobic-hydrophilic
Bubble Point at 23 °C ≥ 1930 mbar (28.0 psig) air with water Durapore® 0.22 μm
Air Diffusion Through a water wet membrane at an ambient temperature of 1.5 bar (22 psi):
≤ 15 mL/min. ≤ 15 mL/min. ≤ 30 mL/min. ≤ 45 mL/min.
Contact Information
Oxidizable Substances Meets the requirements of USP Oxidizable Substances Test for sterile purified water after a water flush of:
≤ 1500 mL ≤ 1500 mL ≤ 3000 mL ≤ 4500 mL
Bacterial Endotoxin Aqueous extraction contains < 0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This
meets the requirements of USP <85>.

37
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Opticap® XL and XLT Sterile and Gamma-Compatible Capsule Filter Specifications (continued) Overview
Selection & Applications Guide
Description Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30
Formats
Sterilization
Gamma-Compatible: Gamma-compatible to 40 kGy. May be autoclaved for 3 cycles of 60 minutes at 123 °C. (Cannot be steam OptiScale® Capsules
sterilized in-line.)
Sterile Capsules: May be autoclaved for 3 cycles of 60 minutes at 123 °C. (Cannot be steam sterilized in-line.) Cartridge Filters
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6). Cartridges
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. Optiseal® Cartridges
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on Millidisk® Cartridges
information provided by raw material suppliers.
Total Organic Carbon (TOC) / This product exhibited less than 500 ppb TOC and conductivity less than 1.3 micro Siemens/cm at 25 ˚C after a
Conductivity 25 ˚C water flush of 36 L. Capsule Filters
*Cage, core, end caps, and capsule housing Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsule Filter Specifications Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
Description Millipak® Final Fill 20 Millipak® Final Fill 40 Millipak® Final Fill 60 Millipak® Final Fill 100 Millipak® Final Fill 200
and Millipak® Barrier Capsules
Nominal Dimensions
Maximum length 8.1 cm (3.2 in.) 8.6 cm (3.4 in.) 10.9 cm (4.3 in.) 11.9 cm (4.7 in.) 14.5 cm (5.7 in.)
Body diameter 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.)
Durapore® 0.1 μm & 0.22 μm
Body diameter w/ anti-roll edges – – – 8.1 cm (3.2 in.) 8.1 cm (3.2 in.)
Filtration Area 100 cm2 (0.11 ft2) 200 cm2 (0.22 ft2) 300 cm2 (0.32 ft2) 500 cm2 (0.54 ft2) 1000 cm2 (1.08 ft2)
Durapore® 0.45 μm
Aseptic Multi-Purpose Port 3.2 mm (1/8 in.) hose barb Durapore® 5.0 μm
Materials of Construction Multimedia Durapore®
Filter membrane: Durapore PVDF (polyvinylidene fluoride) membrane
®
Charged Durapore® 0.22 μm
Support discs Polysulfone
Filter capsule Polysulfone Multilayer Durapore®
Aseptic Multi-Purpose Port (AMPP) Polyethersulfone
AMPP O-rings Silicone Durapore® CBR 0.1 μm &
0.2 μm
Hold-up Volume 20 psi above the Bubble Point Specification for 1 minute
1.1 mL 1.5 mL 3.2 mL 4.8 mL 7.2 mL
Hydrophobic Durapore®
0.22 μm
Maximum Inlet Pressure 60 psi (4.1 bar) at 25 °C 80 psi (5.5 bar) at 25 °C
Hydrophobic-hydrophilic
Maximum Differential Pressure
Forward: 60 psi (4.1 bar) at 25 °C 80 psi (5.5 bar) at 25 °C
Durapore® 0.22 μm
25 psi (1.7 bar) at 80 °C
Reverse: 10 psi (0.7 bar) at 25 °C
Contact Information
Bubble Point at 23 °C ≥ 26 psi (1790 mbar) air with water
Bacterial Endotoxin Aqueous extraction contains < 0.25 EU/mL per device as determined using the Limulus Amebocyte Lysate (LAL)
test, meeting requirements of USP <85>, EP 2.6.14 and JP 4.01.
Microbial Challenge Testing Vents were tested utilizing a bacterial challenge method with 107 Brevundimonas diminuta assuring a sterile
fluid path during actuation.

38
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Millipak® Final Fill Capsule Filter Specifications (continued) Overview

Selection & Applications Guide
Description Millipak® Final Fill 20 Millipak® Final Fill 40 Millipak® Final Fill 60 Millipak® Final Fill 100 Millipak® Final Fill 200
Formats
Total Organic Carbon (TOC) / Samples exhibited < 500 ppb TOC per USP <643> and < 1.3 μS/cm conductivity per USP <645> at 25 °C after
Conductivity sterilization and a water flush of: OptiScale® Capsules
1.0 L 2.0 L 2.0 L 3.0 L 5.0 L Cartridge Filters
Sterilization Device integrity and retention was maintained after 3 autoclave cycles of 90 minutes at 126 °C. Devices can
withstand a dose ≤ 40 kGy gamma exposure.
Cartridges
Toxicity Component materials meet the criteria for Class VI testing based on USP <88> Biological Reactivity, in vivo, Optiseal® Cartridges
USP <87> Biological Reactivity, in vitro, and ISO 10993-5 Tests for in vitro Cytotoxicity. This product also Millidisk® Cartridges
meets physicochemical specifications, as described in USP <661> Containers-Plastics.
Particle Shedding Effluent meets the acceptance criteria set forth in USP <788> for large volume parenterals.
Capsule Filters
Non-Fiber Releasing This product was manufactured with a Durapore® membrane which meets the criteria for a “non-fiber releasing”
filter as defined in 21 CFR 210.3 (b)(6), validated based on large volume parenteral specifications as detailed in Opticap® XL and XLT Capsules
USP <788> Particulate Matter in Injections.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers.
Filters for Final Filtration
Quality Management System These products are manufactured in a facility which is certified to ISO 9001:2015 Quality Management Systems.
® Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

39
 30 30 30
2.0 2.0

Differential P
Differential P

Differential
25 25 25

Delta pressure (psi)

Delta pressure (psi)
10 10 1.5 1.5 20
20 20
15 MCVL 10S 03 15 MCGL 10S 03 1.0 15
1.0
5 5 MCVL 20S 03 MCGL 20S 03
10 10 10
MCVL 30S 03 0.5 MCGL 30S 03 0.5

Filters Containing Durapore 0.45 μm Membrane

5
Durapore Family Guide
5
®
5 MCGL 40S 03
0 0 MCVL 40S 03
® 0

bar
bar
0 0 5 5 10 10 15 15 20 20 25 25 0 0.0 0 0.0
0 1 2 3 4 5 6 0 2 4 6 8 10 12 14 0 1 2 3 4 5 6
Gallons
Gallons
per minute
per minute
Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Typical Clean Water Flow Rates – Cartridge Filters Overview

Hydrophilic
Hydrophilic
Durapore®
Durapore®
Cartridge
Cartridge
Filters
Filters Selection & Applications Guide
Cartridge Filters - 0.45 µm Durapore® Cartridge Filters - 0.45 µm Durapore® Millidisk® Cartridge Filters – 0.45 μm Formats
0.45
0.45
µmwithout
µm
Hydrophilic
Hydrophilic
Durapore®
Durapore®
Cartridge
Cartridge 0.45
0.45
µmµm
Hydrophilic
Hydrophilic
Durapore®
Durapore®
Cartridge
Cartridge Millidisk® 0.45 µm Hydrophilic Filters Millidisk® 5.0 µm Hydrophilic Filters Millidisk® 0.22 µm Hydroph
Membrane Prefilter (CVHL PP) Membrane with Prefilter (CVHL TP) Hydrophilic Durapore® Membrane
without
without
prefilter
prefilter
(CVHL
(CVHL
PP)PP) with
with
prefilter
prefilter
(CVHL
(CVHL
TP)TP) Air Flow Rate @ 25 ºC
0 0 5 5 10 10 15 15 20 20
OptiScale® Capsules
0 0 5 5 10 10 15 15 20 20
0.5 0.5 7 7 L/min L/min L/min
0.6 0.6
10-inch
10-inch 10-inch
10-inch
8 8
50
0 10 20 30 40 50 60 70
50
0 10 20 30 C40artridge
50 60 70Filters
10
0 200 400 600 800
6 6
0.5 0.5
Delta Pressure (psi)
Delta Pressure (psi)

20-inch
20-inch 20-inch
20-inch 7 7

Differential Pressure (psid)

Delta Pressure (psi)
Delta Pressure (psi)
0.4 0.4 45

Differential Pressure (psid)

Differential Pressure (psid)

Cartridges
3.0 45 MCSL 10S 02
30-inch
30-inch 30-inch
30-inch 3.0
5 5 6 6 MCSL 20S 02
40 40
0.4 0.4 2.5 MCSL 30S 01 8
0.3 0.3 35 2.5
Optiseal® 2.0Cartridges
4 4 5 5 35 MCSL 40S 01
30 2.0 30
0.3 0.3 4 4 6
0.2 0.2 3 3 25 25

2 2
0.2 0.2 3 3 20
1.5
20 Millidisk® 1.5Cartridges
4
0.1 0.1 2 2 15 MCHL 10S 03 1.0 15 1.0
1 1 0.1 0.1 MCHL 20S 03
10 10
1 1 MCHL 30S 03 0.5 2
0.5
0.0 0.0 0 0 0.0 0.0 0 0
5 MCHL 40S 03 5
Capsule Filters

bar
0 0 20 20 40 40 6 6 0 0 0 0.0

bar
0 0 20 20 40 40 6 6 0 0 0 0.0 0
0 2 4 6 8 10 12 14 16 18 20
Opticap® XL and XLT Capsules
0 2 4 6 8 10 12 14 16 018 10 20 20 30
Gallons
Gallons
perper
minute
minute Gallons
Gallons
perper
minute
minute Flow Rate (L/min) Flow Rate (L/min) Air Flow Rate (SCFM

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

40
 1.8 TT 12
T2T 25 0.8
0 1 2 3 4 5 0 1 3 4 5 FF

Delta Pressure (psi)

Delta Pressure (psi)

2.0 0.9 1.6 FF
0.7 HH 10
HH
1.8 1.4 T T TH 12 20 TH
TT 25 0.8 0.6
FF FH FH 8

Delta Pressure (psi)

Delta Pressure (psi)

1.6 FF 1.2
0.7 HH 10 0.5
HH 1.0 15
1.4 TH 20 TH 6
0.6

Filters Containing Durapore 0.45 μm Membrane

0.4
® Durapore® Family Guide
FH 0.8 FH 8
1.2
0.5 10 0.3
1.0 15 0.6 4
0.4 6 0.2
0.8 0.4 5 2
10 0.3 0.2 0.1
0.6 4

Typical Clean Water Flow Rates – Opticap XL Capsule Filters 0.4

®
5
0.2 0.0

0.1
0 2 4 6 8 10 12 14 16 18 220
0 Overview
0.0
0 2 4 6 8 10 12 14 16 18 20
0

0.2
0.0 0 0.0 Gallons per minute 0 Selection & minute
Gallons per Applications Guide
Opticap®
Opticap®XLXLCapsule
CapsuleFilters
Filters 0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20
Opticap® XL 2 Capsules – 0.45 μm Opticap® XL 4 Capsules – 0.45 μm Opticap® XL 5 Capsules – 0.45 μm Formats
Durapore® Membrane without prefilter Durapore® Membrane Gallons per minute prefilter
without Gallons per minute
Durapore® Membrane without prefilter
Opticap®
Opticap®XLXL
22Capsule
Capsule
Filters
Filters
0.45
0.45µmµm Opticap®
Opticap®XLXL
44Capsule
Capsule
Filters
Filters
0.45
0.45µmµm Opticap® XL 5 Capsule Filters 0.45 µm Opticap® XL 10 Capsule Filters 0.45 µm
(KPHL)Durapore®
Durapore®Membrane
Membrane without
without prefilter
prefilter
(KPHL)
(KPHL) (KPHL)
Durapore®
Durapore®Membrane
Membrane without
without prefilter
prefilter
(KPHL)
(KPHL)
(KPHL)Durapore® Membrane without prefilter (KPHL)
OptiScale® Capsules
Durapore® Membrane without prefilter (KPHL)
Opticap® XL 4 Capsule Filters 0.45 µm Opticap® XL 5 Capsule Filters 0.45 µm Opticap® XL 10 Capsule Filters 0.45 µm
(KPHL) 0 0
Durapore® 1 1 2 2
Membrane 3 3
without 4 4 5 5
prefilter (KPHL) 0 0 1 1 2 2 3 3 4 4 5 5 Cartridge Filters
2.0 2.0 Durapore®
0.9 0.9 Membrane without prefilter (KPHL) Durapore®
3.0
0
Membrane
5
without
10
prefilter
15 20
(KPHL) 2.5
0 5 10 15 20

1.8 1.8
0 1 T T T 2T 3 4 5 25 25 0.8 0.8
0
TT TT
5 FF
FF 10 15 20
12 12
0
2.5
TT
5 FF 10 15 20
40
Cartridges
TT
(psi) (psi)
Delta Pressure (psi)

Delta Pressure (psi)

(psi) (psi)

Delta Pressure (psi)

30

Delta Pressure (psi)

1.6
0.9 1.6 FF FF 3.0 2.0 FF
0.7 0.7 HH HH 10 10 2.5 HH
Optiseal Cartridges
HH HH 12 HH ®
1.4
0.8 1.4 T T TH
TH 20 20 TH TH 40 30
25 0.6 0.6 TT 2.0
Pressure

Pressure
FF FH 2.5 FH FH 8 8 TT
1.2 FH FF
0.7 1.2 30

Delta Pressure (psi)

HH 10 0.5 0.5 2.0 FF 1.5
20 1.0 1.0
0.6
TH 15 15
2.0
0.4 0.4
HH
6 630
1.5 HH
20 Millidisk® Cartridges
20
Pressure

FH

Pressure
0.8 0.8 8
0.5 1.5 1.0
10 10 0.3 0.3 1.0 20
15 4 4
DeltaDelta

Delta Delta
0.6 0.6 1.5
0.4 6 20 10
0.2 0.2 10
Capsule Filters
0.4 0.4 5 5 0.5
10 2 2 1.0 0.5
0.3 4 1.0
0.1 0.1
0.2 0.2
0.2 10
0 010
Opticap 50XL60 and 80XLT Capsules
0 0 0.0 0.0 0.0 0
5 0.0 0.0
0 0 2 2 4 4 6 6 8 810 1012 1214 1416 1618 1820 2
20 00.5 0 2 2 4 4 6 6 8 810 1012 1214 1416 1618 1820 20 0.5 0 10 20 30 40 50 60 70 80
0.0 ® 0
0.1 0 10 20 30 40 70

0 0.0
0 2 4
Gallons
Gallons
6
perper
minute
minute
8 10 12 14 16 18 20
0 0.0
0 10
Gallons
Gallons
20
perper
30
minute
40
minute
50 60 70 80
0 0.0 Gallons per minute 0 Gallons per minute
0 10 20 30 40 50 60 70 80

Gallons per minute Gallons per minute Gallons per minute Filters for Final Filtration
Opticap®
OpticapOpticap®
®
XL 10 XLXL
5Capsules
5
Capsule
CapsuleFilters
Filters
– 0.45 0.45
0.45 µmµmμm Opticap®
Opticap®
Opticap ®
XLXLXL
1010
10 Capsule
Capsule
Capsules Filters
Filters
–0.450.45
0.45µmµm μm Opticap® XL 10 Capsule Filters 0.45 µm Opticap® XL Capsule Legends Refer to Capsule Connection Type
Durapore®
Durapore® Membrane
Membrane without
without prefilter
prefilter(KPHL)
(KPHL) Durapore®
Durapore® Membrane
Membrane without
without
Millipak® Final Fill Capsules
Durapore ®
Membrane without prefilter Durapore ®
Membrane withprefilter
prefilter
prefilter(KPHL)
(KPHL) Durapore® Membrane with prefilter (KVHL)
Opticap® XL 10 Capsule Filters 0.45 µm Opticap® XL 10 Capsule Filters 0.45 µm Opticap® XL Capsule Legends Refer to Capsule Connection Type TT = 38 mmM (1½ in.) Sanitary Flange Inlet and Outlet
 illidisk Barrier Cartridges
®
(KPHL) (KPHL)Durapore® Membrane without prefilter (KPHL)
0 0 5 5 10 10 15 15 20 20 (KVHL)Durapore®
0 0
Membrane
5 5 10 10
with15prefilter
15
(KVHL)
20 20 0 5 10 15 20
FF = 19 mm (¾ in.) Sanitary Flange Inlet and Outlet
and Millipak® Barrier Capsules
3.0 3.0 2.5
40 40
2.5 2.5
TT = 38 mm (1½ in.) Sanitary Flange Inlet and Outlet
0
TT TT
5 10 15 20 0 T T T 5T 10 15 20 TT HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet
2.5 2.5
FF = 192.0 mm (¾ FFin.) Sanitary Flange Inlet and
30
Outlet

Delta Pressure (psi)

FF FF
(psi) (psi)
Delta Pressure (psi)

30 30
Delta Pressure (psi)
(psi) (psi)

2.5 2.0 2.0

2.5 FF FF
40
HH HH
HH HH HH TH = 38 mm (1½ in.) Sanitary Flange Inlet and
2.0 2.0 TT
30 30
TT HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet 14 mm (9/16 in.) ® Hose Barb Outlet
Pressure

Pressure

30
Durapore 0.1 μm & 0.22 μm
FF FF 30 1.5
2.0 1.5 1.5
2.0
30 1.5 1.5 HH
20 20
HH 20 20
TH = 38 mm (1½ in.) Sanitary Flange Inlet and 20
FH = 19 mm (¾ in.) Sanitary Flange Inlet and
1.0 mm ( 16 in.) Hose Barb Outlet
14 9 /
Pressure

Pressure

1.5
1.0 1.0 20
1.0 1.0
1.5
20 Durapore
14 mm (9/16 in.) ® 0.45
Hose μm
Barb Outlet
Delta Delta

FH = 19 mm (¾ in.) Sanitary Flange Inlet and

Delta Delta

20 10 10 10
10 10
1.00.5
0.5 0.5 0.5
1.0 0.5
14 mm (9/16 in.) Hose Barb Outlet Durapore® 5.0 μm
10 10
10
Multimedia Durapore®
0.0
0.50.0 0 0 0.0 0.0 0 0 0.0 0
0.5
0 0 10 10 20 20 30 30 40 40 50 50 60 60 70 70 80 80 0 0 10 10 20 20 30 30 40 40 50 50 60 60 70 70 80 80 0 10 20 30 40 50 60 70 80

Gallons
Gallons
per
per
minute
minute Gallons per minute Charged Durapore® 0.22 μm
0 0.0
0 10 20 30 40 50 60 70 80
0 0.0
0 10
Gallons
Gallons
20
perper
30
minute
40
minute
50 60 70 80
0

Gallons per minute Gallons per minute Multilayer Durapore®

Opticap®
Opticap® XLXL
1010 Capsule
Capsule Filters
Filters0.45
0.45µmµm Opticap®
Opticap®
XLXL
Capsule
Capsule Legends
LegendsRefer
Refer toto
Capsule
CapsuleConnection
Connection
Type
Type
Durapore®
Durapore® Membrane
Membrane with
with prefilter
prefilter
(KVHL)
(KVHL) Durapore® CBR 70.1 μm &
m Opticap® XL Capsule Legends Refer to Capsule Connection Type TTTT
= =3838mmmm
(1½ (1½ in.)in.)
Sanitary
Sanitary
Flange
FlangeInlet
Inlet
and
and
Outlet
Outlet
VHL) 0 0 5 5 10 10 15 15 20 20 0.2 μm
Opticap® XL Capsule Legends Refer to Capsule Connection FFFF==Type
1919
mmmm
(¾(¾ in.)in.)
Sanitary
SanitaryFlange
Flange Inlet
Inlet
andand
Outlet
Outlet
TT = 2.538
2.5
mm (1½ in.) Sanitary Flange Inlet and Outlet
TT = 38FFmm (1½ in.) T T T T Sanitary Flange Inlet and Outlet HHHH ==1414
mmmm in.)in.)
(9/(169/16 Hose
HoseBarb
BarbInlet
Inlet
and
andOutlet
Outlet Hydrophobic Durapore®
= 2.019
2.0 mm (¾ in.) Sanitary Flange Inlet30 and 30 Outlet
Delta Pressure (psi)
Delta Pressure (psi)

0.22 μm
FF FF
FF = 19HHmm (¾ in.) Sanitary
HH HH
Flange Inlet and Outlet THTH= =3838
mmmm
(1½ (1½ in.)in.)
Sanitary
Sanitary
Flange
FlangeInlet
Inlet
and
and
= 14 mm ( 16 in.) Hose Barb Inlet and Outlet
9 /
30 1414
mmmm in.)in.)
(9/(169/16 Hose
HoseBarb
BarbOutlet
Outlet
HH = 14 THmm
= 38(9/16
1.5 1.5
mm in.)
(1½ in.) Hose Barb Flange
Sanitary Inlet and
Inlet Outlet
20 20and Hydrophobic-hydrophilic
TH = 38 mm (1½ in.)9/ Sanitary Flange Inlet and 14 mm (9/16 FHFH= =19Hose
in.) 19
mmmm
(¾ (¾
Barb in.)in.)
Sanitary
Sanitary
Outlet Flange
Flange Inlet
Inlet
andand
20
1.0 mm ( 16 in.) Hose Barb Outlet
1.014
1414
mmmm in.)in.)
(9/(169/16 Hose
HoseBarb
BarbOutlet
Outlet Durapore® 0.22 μm
FH = 19FHmm
= 19(¾ mmin.)
(¾ Sanitary
in.) Sanitary Flange
Flange Inlet and 14 mm (9/16 in.) Hose Barb Outlet
Inlet10 and
10

14 mm (9/16 in.) Hose Barb Outlet

0.5 0.5

10
0.0 0.0 0 0
0 0 10 10 20 20 30 30 40 40 50 50 60 60 70 70 80 80
Contact Information
0 Gallons
Gallons
perper
minute
minute
77
7

41
 35 30

30 HH 25 HH
TH TH
25 BB BB
TT 20 TT

Filters Containing Durapore 0.45 μm Membrane ® Durapore® Family Guide

20
15
15

Delta pressure (psi)

Delta pressure (psi)
10
10

Typical Clean Water Flow Rates – Opticap XLT Capsule Filters ®

5 5 Overview
0
0 5 10 15 25
0
0
Selection
5 10
& 15Applications
20 25
Guide
Opticap®
Opticap Opticap®
®
XLT XLT
10 XLT
Capsule
Capsule
Capsules Filters
Filters
– 0.45 µm Opticap® XLT 20 Capsules – 0.45 µm Opticap® XLT 30 Capsules – 0.45 µm
20

Typical Clean
Typical Water
Clean Flow Water RatesFlow Rates Gallons per minute
Formats
Gallons per minute

Durapore® Membrane without prefilter Durapore® Membrane without prefilter Durapore® Membrane without prefilter
(KPHL)Opticap®
Opticap®
XLTXLT
1010
Capsule
Capsule
Filters
Filters
0.45
0.45
µmµm Opticap®
(KPHL)Opticap®
XLTXLT
2020
Capsule
Capsule
Filters
Filters
0.45
0.45
µmµm (KPHL)Opticap® XLT 30 Capsule Filters 0.45 µm Opticap®OXLT
ptiScale ®
Capsules
Capsule Legends Refer to Connection Type
Durapore®
Durapore®
Membrane
Membrane
without
without
prefilter
prefilter
(KPHL)
(KPHL) Durapore®
Durapore®
Membrane
Membrane
without
without
prefilter
prefilter
(KPHL)
(KPHL) Durapore® Membrane without prefilter (KPHL)
35 35
Millipak® Final Fill 20/40/60
Millipak® Final
Capsule
FillFilters
20/40/60
withCapsule
0.1 µm Filters with 0.1 µm
30 30
Millipak® Final Fill 100/200
Millipak®Capsule
Final Fill
Filters
100/200
withCapsule
0.1 µm Filters with 0.1 µm TT = 38 mm (11/2 in.) Sanitary
Cartridge Flange Inlet and Outlet
Filters
Hydrophilic Durapore Hydrophilic
®
Membrane Durapore® Membrane Hydrophilic Durapore Hydrophilic
®
Membrane Durapore® Membrane 30
TH = 38 mm (11/2 in.) Sanitary Flange Inlet and
16 mm Cartridges
20 H,
30 30 Typical HH HH 40
20 H,
H,Typical
Typical 60
40 H/T,
H, Typical
Typical 60 H/T, Typical HH HH 100 B/T, Typical 100200
B/T,
B/T,
Typical
Typical 200 B/T, Typical
HH
50 50
TH TH
25 25
50 TH TH 50 25
TH
(5/8 in.) Hose Barb Outlet
Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

25 25 BB BB BB BB BB
40 40
TT TT 20 20 40 TT TT 40 20 TT HH = 16 mmOptiseal
(5/8 in.) Hose
® Barb Inlet and Outlet
Cartridges
20 20
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet
30
15 15
30 15 15 30 30 15 ®
Millidisk Cartridges
20 20 20 20

Delta pressure (psi)

Delta pressure (psi)
Delta pressure (psi)
Delta pressure (psi)

Delta pressure (psi)

10 10 10
10 10
10 10 10 10
5 5 5 5 5 Capsule Filters
0 0 0 0
0 0
0
0
0 5
0.5
5
0
10 10 15 15
0.5
1
20 20 25 25
1.5
1 21.5 0
0
0
0
2 0
5 5 10 10
2 0
15 15
4
20 20
2
25 25
6 4 8 6 10 8 120
0
10
5
12
10 15 20 25
Opticap® XL and XLT Capsules
Flow Rate (L/min) Flow Rate (L/min) Gallons
Gallons per minute
per minute Flow Rate (L/min) Flow Rate (L/min)
Gallons per minute
Gallons per minute Gallons per minute

Opticap®
Opticap®
XLTXLT
3030
Capsule
Capsule
Filters
Filters
0.45
0.45
µmµm Opticap®
Opticap®
XLTXLT
Capsule
Capsule
Legends
Legends
Refer
Refer
to to
Connection
Connection
Type
Type Filters for Final Filtration
OpticapDurapore®
®
XLT Capsule
Durapore® Legends
Membrane
Membrane
without Refer
without to(KPHL)
prefilter
prefilterCapsule
(KPHL) Connection Type Millipak® Final Fill 100/200
Millipak®Capsule
Final Fill
Filters
100/200
withCapsule
0.22 µmFilters with 0.22 µm
TT = 38 mm
30 30 (11/2 in.) Sanitary Flange Inlet and Outlet
TT TT
= 38
= 38 mm mm (11/2
(11/2in.)in.)
Sanitary
Sanitary
Flange
Hydrophilic Flange Inlet
Durapore Inlet
andand
Hydrophilic Outlet Membrane Hydrophilic Durapore® Cartridge Filters
Outlet
Membrane Durapore ® ® Millipak® Final Fill Capsules
Millipak Final Fill 20/40/60
Millipak Final
CapsuleFillFilters
20/40/60
withCapsule
0.22 µmFilters with 0.22 µm THTH = 38
= 38mm mm(11/2
(11/2
®
in.)in.)
Sanitary
Sanitary
Flange
Flange Inlet
®
Inlet
andand
TH = 38 mm
25 25
(11/2Hydrophilic
in.)
HH HH Sanitary
Durapore Flange
Hydrophilic
Membrane Inlet and
Durapore Membrane16 mm (5/8 in.) Hose Barb
1616mm mm(5/8(5/8
Outlet 100
100 B, Typical
in.)in.)
HoseHose
100 K/L,
Barb
Barb
B, Typical
Outlet
Typical
Outlet
100
100K/L,
® F/T,Typical
Typical 100 F/T, Typical ®
M
 illidisk® Barrier Cartridges
0.45 µm Hydrophilic Durapore® Cartridge 0.45 µm Hydrophilic Durapore®
® Cartridge
with prefilterand Millipak Barrier Capsules
TH TH 20 All Types,
HH = 50
16 mm20 All Types, Typical
(5/8 in.)
50
40 All Typical
Types, Typical 40 All Types,
BB BB Hose Barb Inlet and Outlet
60 All Typical
Types, Typical 60 All Types, Typical
50
200 B, Typical
50
200
200 K/L,
B, Typical
Typical 200
200K/L,
F/T,Typical
Typical 200 F/T, Typical
20 20 TT TT HHHH = 16= 16mm mm (5/8(5/8
in.)in.)
Hose
HoseBarb
BarbInlet
Inlet
andand Outlet
Outlet without prefilter (CVHL PP) (CVHL TP)
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet
Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

0 5 10 15 20
40 40 BBBB
= 25
= 25
mm
40mm
(1 (1
in.)in.)
Hose
Hose
Barb
40 Barb
Inlet
Inlet
andand
Outlet
Outlet 0.5 7 0.6
0 5 10 15 20
15 15 8
30 30 30 30 10-inch 10-inch
6
0.5 Durapore 0.1 μm & 0.22 μm
®

Delta Pressure (psi)

20-inch 20-inch
7

Delta Pressure (psi)

0.4
Delta pressure (psi)
Delta pressure (psi)

10 10 30-inch 30-inch
20 20 20 20 5 6
5 5 0.3
4
0.4
Durapore® 0.45 μm 5
10 10 10 10
Durapore® 5.0 μm
0.3 4
0 0 0.2 3
0 0 0 5 05 10 10 15 15 20 20 25 25 0 0 3
30 2 4 0 6 2 8 4 10 6 12 8 14 10 16 12 18 14 20 16 18 20
Typical Clean Water Flow Rates – Millipak Final Fill Capsule Filters
0.2
0 0.5 0 1 0.5 1.5 1 2 1.5 2.5 2 3 2.5 ®
Multimedia Durapore 2
Gallons
Gallons
per minute
per minute 2 ®
0.1
Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min) 0.1
1
1
0.0 0 0.0
Charged Durapore® 0.22
0
μm
0 20 40 6 0 0 20 40 6 0
Hydrophilic
HydrophilicDurapore®
Durapore®Cartridge
Cartridge
Filters
Filters Multilayer Durapore®
Millipak® Final Fill 20/40/60 Capsules – 0.45 μm Millipak® Final Fill 100/200 Capsules – 0.45 μm Gallons per minute Gallons per minute
Hydrophilic Durapore
Millipak MillipakMembrane
®
Final Fill 20/40/60 Final
Capsule
FillFilters
20/40/60
withCapsule
0.45 µmFilters with 0.45 µm ® ® Hydrophilic
Millipak Durapore
Final Fill 100/200
Millipak Capsule
Final Fill
®
Filters
® Membrane
100/200
with
Capsule
0.45 µmFilters with 0.45 µm
® Durapore® CBR 0.1 μm &
0.45
0.45µmµm Hydrophilic
Hydrophilic Durapore®
Durapore®
Hydrophilic Durapore
Cartridge
Cartridge
Hydrophilic
Membrane Durapore Membrane
0.450.45 µmµm Hydrophilic
Hydrophilic Durapore®
Durapore® Cartridge
Cartridge
Hydrophilic Durapore Hydrophilic
Membrane Durapore Membrane
0.2 μm
® ® ® ®

without
without prefilter
prefilter
20 H, Typical (CVHL
40 (CVHL
20 H, PP)PP) 60
H,Typical
Typical 40 H,
H, Typical
Typical 60
60 T,
H,Typical
Typical with
60 T,withprefilter
prefilter
Typical (CVHL
(CVHL
100 TP)TP) 100
B, Typical 100 T,
B, Typical
Typical 100 B,
200 T, Typical
Typical 200 T,
200 B,Typical
Typical 200 T, Typical
50 0 0 50 5 5 10 10 15 15 20 20 0 500 5 5 1050
10 15 15 20 20
0.5 0.5 7 7 0.6 0.6 Hydrophobic Durapore®
Differential Pressure (psid)

Differential Pressure (psid)

(psi) (psid)

Differential Pressure (psid)

40 40 40 40 8 8
10-inch
10-inch
6 6
0.5 0.5
10-inch
10-inch
0.22 μm
Delta Pressure (psi)
Delta Pressure (psi)

20-inch
20-inch 20-inch
20-inch
PressurePressure

7 7
Delta Pressure (psi)

0.4 0.4
30 30 30-inch
30-inch
5 5
30 30-inch
30-inch 30
Hydrophobic-hydrophilic
6 6
0.4 0.4
0.3 0.3
20 20 20 20 5 5
DeltaDifferential

4 4
0.3 0.3 4 4
Durapore® 0.22 μm
10 0.2 0.2 10 3 3 10 10
0.2 0.2 3 3
2 2
0 0.1 0.1
0 0 0 2 2
0 2 0 4 2 6 4 8 6 10 8 0.1 0.1 100 5 0 10 5 15 10 20 15 25 20 30 25 30
Flow Rate (L/min)
1 1
Flow Rate (L/min)
1
Flow Rate (L/min)
1
Flow Rate (L/min)
Contact Information
0.0 0.0 0 0 0.0 0.0 0 0
0 0 20 20 40 40 6 6 0 0 0 0 20 20 40 40 6 6 0 0

Gallons
Gallons
perper
minute
minute Legend Gallons
Legend
Gallons
perper
minute
minute
B = 13 mm (½B in.)
= 13stepped
mm (½hose
in.) barb
stepped
inlethose
and barb
outletinlet and outlet
Millipak® Final Fill 60/200
MillipakCapsule
®
Final Fill
Filters
60/200
withCapsule
5.0 µm Filters with 5.0 µm
Hydrophilic Durapore Hydrophilic
®
Membrane Durapore® Membrane
C = 19 mm (¾
C in.)
= 19sanitary
mm (¾flange
in.) sanitary
inlet and
flange inlet and
60 H, Typical 60
60 T,
H,Typical
Typical 200
60 T,
B,Typical
Typical 200
200 T,
B,Typical
Typical 200 T, Typical
6 mm (¼ in.) 6
hose
mmbarb
(¼ in.)
outlet
hose barb outlet
5 5
F = 19 mm (¾F in.)
= 19sanitary
mm (¾flange
in.) sanitary
inlet and
flange
outletinlet and outlet
42
rential Pressure (psid)

rential Pressure (psid)

4 4 H = 6 mm (¼ H
in.)
=6 stepped
mm (¼hose
in.) barb
stepped
inlethose
and barb
outletinlet and outlet
3 3 K = 19mm (¾Kin.)
= 19mm
sanitary
(¾flange
in.) sanitary
inlett and
flange inlett and
13 mm (½ in.)
13hose
mm barb
(½ in.)
outlet
hose barb outlet
2 2
L = 38 mm (1L½=in.)
38 mm
sanitary
(1 ½flange
in.) sanitary
inlet and
flange inlet and
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
OptiScale Capsule Filters
® Formats
OptiScale® Capsules
Cartridge Filters
S H L A
Cartridges
Optiseal® Cartridges
OptiScale® Pore Size Disc Size Quantity per pkg.
Capsule Filter Millidisk® Cartridges
HL = 0.45 µm 25 = 25 mm 3 = 3/pk
47 = 47 mm 6 = 6/pk
Capsule Filters
Membrane Type May be Connection Type Opticap® XL and XLT Capsules
Autoclaved
V = Durapore ®
HH = 6 mm (1/4 in.) Hose Barb Inlet and Outlet
with prefilter FF = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet
P = Durapore®
Filters for Final Filtration
FH = 19 mm (3/4 in.) Sanitary Flange Inlet and
without prefilter 6 mm (1/4 in.) Hose Barb Outlet Millipak® Final Fill Capsules
NB = Female Luer-Lok™ Inlet and Male Luer-Lok™ Outlet
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Cartridge Filters
Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
C V H L Durapore® 5.0 μm
Multimedia Durapore®
Cartridge Pore Size Cartridge Length Quantity per pkg. Charged Durapore® 0.22 μm
Filter
HL = 0.45 µm 5=5  -inch (Code 0 and 7 1 = 1/pk (5-inch only) Multilayer Durapore®
only without prefilter) 3 = 3/pk
1 = 10-inch Durapore® CBR 0.1 μm &
Membrane Type Cartridge Code 2 = 20-inch Connection Type 0.2 μm
V = Durapore® 0 = (2-222) O-ring 3 = 30-inch TP = With prefilter Hydrophobic Durapore®
5 = (2-222) O-ring 4 = 40-inch (Code 7 only) PP = Without prefilter 0.22 μm
with spear
7 = (2-226) O-ring
Hydrophobic-hydrophilic
with locking tab Durapore® 0.22 μm
and spear

Contact Information

43
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Millidisk® Cartridge Filters
OptiScale® Capsules
Cartridge Filters
M C H L 0 3 Cartridges
Optiseal® Cartridges
Millidisk Cartridges
®
Pore Size Millidisk Stack Size
® Quantity per pkg. Millidisk® Cartridges
HL = 0.45 μm 40S = 40-stack 3 = 3/pk
30S = 30-stack
Capsule Filters
20S = 20-stack
10S = 10-stack Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Opticap® XL Capsule Filters

Durapore® 0.1 μm & 0.22 μm

K H L Durapore® 0.45 μm
Durapore® 5.0 μm
Opticap XL
®
Pore Size Capsule Sizes Quantity per pkg. Multimedia Durapore®
Capsule Filter
HL = 0.45 µm 02 = Opticap
®
XL 2 1=1  /pk (Opticap 5 and
®

Opticap® 10 only) Charged Durapore® 0.22 μm

04 = Opticap® XL 4
05 = Opticap® XL 5 3 = 3/pk (Opticap® XL 2 and Multilayer Durapore®
Opticap® XL 4 only)
10 = Opticap® XL 10
Durapore® CBR 0.1 μm &
Membrane Type Sterilization 0.2 μm
V = Durapore® with prefilter A = Autoclavable Hydrophobic Durapore®
(Opticap® XL 10 only) G = Gamma (Opticap® XL 10 only) 0.22 μm
P = Durapore® without prefilter S = Sterile (Opticap® XL 10 only)
Hydrophobic-hydrophilic
Connection Type Durapore® 0.22 μm
TT = 38 mm (1 1/2 in.) Sanitary Flange Inlet and Outlet
FF = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet
HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet Contact Information
TH = 38 mm (1 1/2 in.) Sanitary Flange Inlet and
14 mm (9/16 in.) Hose Barb Outlet
FH = 19 mm (3/4 in.) Sanitary Flange Inlet and
14 mm (9/16 in.) Hose Barb Outlet

44
Filters Containing Durapore® 0.45 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Opticap® XLT Capsule Filters
OptiScale® Capsules
Cartridge Filters
K P H L T 1 Cartridges
Optiseal® Cartridges
Membrane Type Sterilization Gauge Port Quantity per pkg. Millidisk® Cartridges
P=D
 urapore ®
G=G  amma- T=W
 ithout 1 = 1/pk
without prefilter Compatible gauge port
S = Sterile Capsule Filters
Opticap® XL and XLT Capsules
Opticap® XLT Pore Size Capsule Sizes Connection Type
Capsule Filter
HL = 0.45 µm 1 = Opticap® XLT 10 TT = 38 mm (1 1/2 in.) Sanitary Flange Inlet and Outlet
2 = Opticap® XLT 20 HH = 16 mm (5/8 in.) Hose Barb Inlet and Outlet Filters for Final Filtration
3 = Opticap® XLT 30 TH = 3
 8 mm (1 1/2 in.) Sanitary Flange Inlet and Millipak® Final Fill Capsules
Accessory 16 mm (5/8 in.) Hose Barb Outlet
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet M
 illidisk® Barrier Cartridges
Description Qty/Pk Cat. No.
and Millipak® Barrier Capsules
Standard Opticap® XLT Capsule Filter Stand 1/pk XLTSTAND1

Durapore® 0.1 μm & 0.22 μm

Millipak® Final Fill Capsule Filters Durapore® 0.45 μm

Durapore® 5.0 μm
Multimedia Durapore®
M F H L 3
Charged Durapore® 0.22 μm
Multilayer Durapore®
Millipak® Final Pore Size Quantity per pkg.
Fill Filter
Durapore® CBR 0.1 μm &
HL = 0.45 μm 3 = 3/pk 0.2 μm
Hydrophobic Durapore®
Millipak Final Fill Filter Series
® 0.22 μm
02G = 20, Non-sterilized Hydrophobic-hydrophilic
02S = 20, Sterilized by Gamma Radiation Connection Type Durapore® 0.22 μm
04G = 40, Non-sterilized Millipak® Final Fill 20, 40, 60
04S = 40, Sterilized by Gamma Radiation H = 6 mm (1/4 in.) Stepped Hose Barb Inlet and Outlet
06G = 60, Non-sterilized Millipak® Final Fill 60, 100, 200 Contact Information
06S = 60, Sterilized by Gamma Radiation T = 38 mm (1½ in.) Sanitary Flange Inlet and Outlet
10G = 100, Non-sterilized
Millipak® Final Fill 100, 200
10S = 100, Sterilized by Gamma Radiation
B = 13 mm (1/2 in.) Stepped Hose Barb Inlet and Outlet
20G = 200, Non-sterilized
20S = 200, Sterilized by Gamma Radiation

45
Filters Containing Durapore 5.0 µm Membrane ® Durapore® Family Guide

Overview
For particle removal in sterile bulk applications
Selection & Applications Guide
Formats
OptiScale® Capsules
Filters containing Durapore® 5.0 μm
Cartridge Filters
hydrophilic polyvinylidene (PVDF) membrane
Cartridges
are ideally suited for removing particles in
sterile bulk liquids. Optiseal® Cartridges
Millidisk® Cartridges

Capsule Filters
Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
Benefits Filter Formats 0.22 μm
• Low protein binding membrane yields high protein • Millidisk® cartridges Hydrophobic-hydrophilic
recovery with minimal product loss Durapore® 0.22 μm
• Millipak Final Fill capsules
®

• Broad chemical compatibility, low extractables

• For filtration processes requiring high flow rates Contact Information
and throughputs

46
Filters Containing Durapore® 5.0 μm Membrane Durapore® Family Guide

Millidisk® Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Millidisk® 10 Filters Millidisk® 20 Filters Millidisk® 30 Filters Millidisk® 40 Filters
Formats
Filtration Area 500 cm2 (0.54 ft2) 1000 cm2 (1.08 ft2) 1500 cm2 (1.61 ft2) 2000 cm2 (2.15 ft2)
Materials of Construction OptiScale® Capsules
Filter membrane: Durapore® PVDF membrane Cartridge Filters
Structural components: Polysulfone
O-rings: Silicone Cartridges
Maximum Differential Pressure Optiseal® Cartridges
Forward: 4.1 bar (60 psid) at 25 °C
1.7 bar (25 psid) at 80 °C Millidisk® Cartridges
345 mbar (5 psid) at 123 °C
Reverse: 690 mbar (10 psid) at 25 °C
Capsule Filters
Connections Millidisk® filters incorporate a double 2–118 (silicone) O-ring seal and are used with Millidisk® or Millidisk®/
Milligard® stainless steel housings. Opticap® XL and XLT Capsules
Gravimetric Extractables Through a water wet membrane at an ambient temperature of 1.5 bar (22 psi):
2.5 mg/unit 5 mg/unit 7.5 mg/unit 10 mg/unit Filters for Final Filtration
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for sterile purified water after steaming and a water Millipak® Final Fill Capsules
flush of 200 mL.
M
 illidisk® Barrier Cartridges
Bacterial Endotoxin An aqueous extraction from a Millidisk® filter contains < 0.5 EU/mL bacterial endotoxin as determined by the
Limulus Amebocyte Lysate (LAL) test. This meets the requirements of USP <85>. and Millipak® Barrier Capsules
Sterilization
Autoclave: 126 °C, 60 minutes, up to 5 times
Durapore® 0.1 μm & 0.22 μm
Steam-in-place: 135 °C, 60 minutes, up to 5 times
Toxicity Component materials meet the requirements of USP <88> Biological Reactivity Tests for Class VI Plastics. Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

47
Filters Containing Durapore® 5.0 μm Membrane Durapore® Family Guide

Millipak® Final Fill Capsule Filter Specifications Overview

Selection & Applications Guide
Description Millipak® Final Fill 60 Millipak® Final Fill 200
Formats
Nominal Dimensions
Maximum length 10.9 cm (4.3 in.) 14.5 cm (5.7 in.) OptiScale® Capsules
Body diameter 7.6 cm (3.0 in.) 7.6 cm (3.0 in.)
Body diameter w/ anti-roll edges – 8.1 cm (3.2 in.) Cartridge Filters
Filtration Area 300 cm (0.32 ft )
2 2
1000 cm (1.08 ft )
2 2 Cartridges
Materials of Construction Optiseal® Cartridges
Filter membrane: Durapore® PVDF (polyvinylidene fluoride) membrane
Support discs Polysulfone
Millidisk® Cartridges
Filter capsule Polysulfone
Aseptic Multi-Purpose Port (AMPP) Polyethersulfone Capsule Filters
AMPP O-rings Silicone
Opticap® XL and XLT Capsules
Hold-up Volume 20 psi above the Bubble Point Specification for 1 minute
3.2 mL 6.2 mL
Filters for Final Filtration
Maximum Inlet Pressure 80 psi (5.5 bar) at 25 °C
Millipak® Final Fill Capsules
Maximum Differential Pressure
Forward: 50 psi (3.5 bar) at 25 °C M
 illidisk® Barrier Cartridges
25 psi (1.7 bar) at 80 °C and Millipak® Barrier Capsules
Reverse: 10 psi (700 mbar) at 25 °C
Microbial Challenge Testing Vents were tested utilizing a bacterial challenge method with 107 Brevundimonas diminuta assuring a sterile
fluid path during actuation. Durapore® 0.1 μm & 0.22 μm
Bacterial Endotoxin Aqueous extraction contains <0.25 EU/mL per device as determined using the Limulus Amebocyte Lysate (LAL) Durapore® 0.45 μm
test, meeting requirements of USP <85>, EP 2.6.14 and JP 4.01.
Total Organic Carbon (TOC) / Samples exhibited < 500 ppb TOC per USP <643> and less than 1.3 µS/cm conductivity per USP <645>
Durapore® 5.0 μm
Conductivity at 25 °C after sterilization and a water flush of: Multimedia Durapore®
2.0 L 5.0 L
Charged Durapore® 0.22 μm
Sterilization Device integrity and retention was maintained after 3 autoclave cycles of 90 minutes at 126 °C. Devices can
withstand a dose ≤ 40 kGy gamma exposure. Multilayer Durapore®
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. Durapore® CBR 0.1 μm &
Particle Shedding Effluent meets the acceptance criteria set forth in USP <788> for large volume parenterals.
0.2 μm
Non-Fiber Releasing This product was manufactured with a Durapore® membrane which meets the criteria for a “non-fiber releasing” Hydrophobic Durapore®
filter as defined in 21 CFR 210.3 (b)(6), validated based on large volume parenteral specifications as detailed in 0.22 μm
USP <788> Particulate Matter in Injections.
Hydrophobic-hydrophilic
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
Durapore® 0.22 μm
information provided by raw material suppliers.
Quality Management System These products are manufactured in a facility which is certified to ISO® 9001:2015 Quality Management Systems.
Contact Information

48
 MCGL 30S 03 MCGB 30S 01 0.5
0.5 0.5

Different

Different
5 MCGL 40S 03 5 MCGB 40S 01
10 10

bar
0

bar
0.0
bar 0 0.0 0.0
0 2 4 6 8 10 12 14 0 1 2 3 4 5 6 7 8 9 10

Flow Rate (L/min) 0 Rate (L/min)

Flow 0
0 2 4 6 8 10 0 5 10 ® Family
15 20 25
Filters Containing Durapore® 5.0 μm Membrane Flow Rate (L/min)
Durapore Guide
Flow Rate (L/min)

Typical Clean Water Flow Rates Overview

Legend Selection & Applications Guide
Millidisk® Cartridge Filters – 5.0 μm Millipak® Final Fill 60/200 Capsules – 5.0 μm
Millidisk® 5.0 µm Hydrophilic Filters
Durapore® Membrane
Millidisk® 0.22 µm Hydrophobic Filters
Durapore® Membrane B = 13 mm (½Formats
in.) stepped hose barb inlet and outlet
Air Flow Rate @ 25 ºC Millipak® Final Fill 60/200 Capsule Filters with 5.0 µm
Hydrophilic Durapore® Membrane
C = 19 mm (¾ in.) sanitary® flange
OptiScale inlet and
Capsules
L/min L/min 6 mm (¼ in.) hose barb outlet
0 10 20 30 40 50 60 70 0 200 400 5600
60 H, Typical
800 1000 1200
60 T, Typical
1400
200 B, Typical 200 T, Typical Cartridge Filters
50 10 .7 F = 19 mm (¾ in.) sanitary flange inlet and outlet
Cartridges

Differential Pressure (psid)

Differential Pressure (psid)

Differential Pressure (psid)

MCSL 10S 02
45
MCSL 20S 02
3.0 4 H = 6 mm (¼ in.) stepped hose barb inlet and outlet
40 MCSL 30S 01 8 Optiseal® Cartridges
35 MCSL 40S 01
2.5
3 K = 19mm (¾ in.) sanitary flange inlett and
13 mm (½ in.)Millidisk
hose barbCartridges
®
30 2.0 6 outlet
25 2 .35
1.5 MCGB 10 L = 38 mm (1 ½ in.) sanitary flange inlet and
20 4
1 MCGB 20 Capsule
13 mm (½ in.) steppedFilters
hose barb outlet
15 1.0
Opticap
T = 38 mm (1 ½ in.) sanitary XL andinlet
XLT and
Capsules
MCGB 30 ®
10
0.5
2 0 MCGB 40
flange outlet
5 0 2 4 6 8 10
bar

bar
bar

0 0.0 0 0
0 2 4 6 8 10 12 14 16 18 20 0 10 20 30 40 50
Flow Rate (L/min) Filters for Final Filtration
Flow Rate (L/min) Air Flow Rate (SCFM) Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

49
Filters Containing Durapore® 5.0 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Millidisk® Cartridge Filters
OptiScale® Capsules
Cartridge Filters
M P S L 1 Cartridges
Optiseal® Cartridges
Millipak Filter
®
Membrane Pore Size Millipak® Stack Size Package Quantity Millidisk® Cartridges
SL = Durapore 5.0 μm
®
40S = 40-stack 2 = 2 per package
30S = 30-stack (Millidisk(R) 10, 20)
1 = 1 per package Capsule Filters
20S = 20-stack
(Millidisk(R) 30, 40) Opticap® XL and XLT Capsules
10S = 10-stack

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Millipak® Final Fill Capsule Filters
Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
M F S L 3
Durapore® 5.0 μm
Multimedia Durapore®
Millipak® Final Membrane Pore Size Quantity per pkg.
Fill Filter
SL = Durapore® 5.0 μm 3 = 3/pk
Charged Durapore® 0.22 μm
Multilayer Durapore®

Millipak® Final Fill Filter Series Durapore® CBR 0.1 μm &

0.2 μm
06G = 60, non-sterilized
06S = 60, sterilized by gamma radiation Connection Type Hydrophobic Durapore®
20G = 200, non-sterilized Millipak Final Fill 60
® 0.22 μm
20S = 200, sterilized by gamma radiation H = 6 mm (1/4 in.) Stepped Hose Barb Inlet and Outlet Hydrophobic-hydrophilic
Millipak® Final Fill 200 Durapore® 0.22 μm
B = 13 mm (1/2 in.) stepped hose barb inlet and outlet
Millipak® Final Fill 60, 200
T = 38 mm (1½ in.) sanitary flange inlet and outlet Contact Information

50
Durapore Multimedia Filters
® Durapore® Family Guide

Overview
With integrated prefilter for sterile filtration of fouling and plugging solutions
Selection & Applications Guide
Formats
OptiScale® Capsules
Durapore® Multimedia filters combine a
Cartridge Filters
single or double layer of Milligard® prefilter
Cartridges
media with a 0.22 μm hydrophilic Durapore®
polyvinylidene fluoride (PVDF) membrane in Optiseal® Cartridges
one filter, enabling prefiltration and sterile Millidisk® Cartridges
filtration in a single device.
Capsule Filters
Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Benefits Media/Membrane Types

Durapore® 0.1 μm & 0.22 μm
• Process efficiency — prefiltration and sterile filtration
Milligard®/Durapore® Membrane Durapore® 0.45 μm
in one step
(Single Layer Prefilter)
Durapore® 5.0 μm
• High retention efficiency and throughput
• 0.2 μm/0.22 μm Multimedia Durapore®
• Low protein binding membrane yields high protein
• 0.5 μm/0.22 μm Charged Durapore® 0.22 μm
recovery with minimal product loss
• 1.2 μm/0.22 μm Multilayer Durapore®
• Broad chemical compatibility, low extractables
Milligard® pore sizes are nominal Durapore® CBR 0.1 μm &
• For filtration processes requiring high flow rates 0.2 μm
and throughputs
Milligard®/Durapore® Membrane Hydrophobic Durapore®
(Double Layer Prefilter) 0.22 μm
Filter Formats • 1.2 μm/0.5 μm/0.22 μm Hydrophobic-hydrophilic
• OptiScale capsules
® Durapore® 0.22 μm
• 0.5 μm/0.2 μm/0.22 μm
• Cartridge filters • 1.2 μm/0.2 μm/0.22 μm
Contact Information
• Opticap XL capsules
®

51
Durapore® Multimedia Filters Durapore® Family Guide

OptiScale® Capsule Filter Specifications (Single and Double Layer Prefilters) Overview
Selection & Applications Guide
Description OptiScale® 25 Capsule OptiScale® 47 Capsule
Formats
Nominal Dimensions
Maximum length: 39 mm (1.52 in.) with female Luer-Lok™ 82 mm (3.24 in.) with flange inlet/hose barb outlet OptiScale® Capsules
inlet/male luer slip outlet 74 mm (2.91 in.) with flange inlet/flange outlet
94 mm (3.70 in.) with hose barb inlet/hose barb outlet Cartridge Filters
Body Diameter: 31 mm (1.21 in.) 69 mm (2.75 in.) Cartridges
Weight: 0.19 oz (5.5 g) 2.3 oz (67 g)
Optiseal® Cartridges
Filtration Area 3.5 cm2 17.7 cm2
Millidisk® Cartridges
Materials of Construction
Filter membrane: Hydrophilic PVDF Hydrophilic PVDF
Filter media: Mixed esters of cellulose Mixed esters of cellulose Capsule Filters
Structural components: Polypropylene Polycarbonate
Supports: Polypropylene Polypropylene Opticap® XL and XLT Capsules
Vent cap: Polypropylene PVDF
Internal seal rings: — Fluoroelatomers
Filters for Final Filtration
Housing Vent Capped vent with female Luer connections on inlet side Adjustable vent with male luer and female Luer-Lok™
of device. connections on inlet side of device. Millipak® Final Fill Capsules
Maximum Inlet Pressure 4.1 bar (60 psi) at 25 °C 5.5 bar (80 psi) at 25 °C M
 illidisk® Barrier Cartridges
Oxidizable Substances — Meets the USP Oxidizable Substances Test requirements and Millipak® Barrier Capsules
for sterile purified water after a water flush of ≤ 100 mL.
Sterilization May be autoclaved for 1 cycle of 60 min at 123 °C. May be autoclaved for 3 cycles of 60 minutes at 123 °C.
Durapore® 0.1 μm & 0.22 μm
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Durapore® 0.45 μm
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers. Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Opticap® XL Capsule and Cartridge Filter Specifications
Multilayer Durapore®
Description Opticap® XL 10 Capsule Cartridge (per 10-inch) Durapore® CBR 0.1 μm &
Single Layer Prefilter Double Layer Prefilter Single Layer Prefilter Double Layer Prefilter 0.2 μm
Nominal Dimensions Hydrophobic Durapore®
Maximum length: 33.5 cm (13.2 in.) 33.5 cm (13.2 in.) — —
0.22 μm
Body diameter: 10.7 cm (4.2 in.) 10.7 cm (4.2 in.) 6.9 cm (2.7 in.) 6.9 cm (2.7 in.)
Filtration Area 0.69 m2 (7.4 ft2) 0.56 m2 (6.0 ft2) 0.69 m2 (7.4 ft2) 0.56 m2 (6.0 ft2)
Hydrophobic-hydrophilic
Durapore® 0.22 μm
Materials of Construction
Filter membrane: Hydrophilic PVDF Hydrophilic PVDF
Filter media: Mixed esters of cellulose Mixed esters of cellulose
Contact Information
Film edge: Polypropylene Polypropylene
Structural components: Polypropylene Polypropylene
Supports: Polypropylene Polypropylene
Vent O-rings: Silicone —
O-rings: — Silicone
Housing Vent 1
/4 in. hose barb with double O-ring seal; —
connects to 1/8 in. tubing
Nominal Vent to Vent Diameter 14.5 cm (5.7 in.)
52
Durapore® Multimedia Filters Durapore® Family Guide

Opticap® XL Capsule and Cartridge Filter Specifications (continued) Overview

Selection & Applications Guide
Description Opticap® XL 10 Capsule Cartridge (per 10-inch)
Formats
Single Layer Prefilter Double Layer Prefilter Single Layer Prefilter Double Layer Prefilter
Housing Vent /4 in. hose barb with double O-ring seal; connects to
1
— — OptiScale® Capsules
/8 in. tubing
1
Cartridge Filters
Maximum Inlet Pressure 5.5 bar (80 psi) at 25 °C
2.8 bar (40 psi) at 60 °C
Cartridges
1.0 bar (15 psi) at 80 °C Optiseal® Cartridges
Maximum Differential Pressure
Millidisk® Cartridges
Forward: 5.5 bar (80 psid) at 25 °C 5.5 bar (80 psid) at 25 °C
1.0 bar (15 psid) at 80 °C 1.7 bar (25 psid) at 80 °C
345 mbar (5 psid) at 123 °C
Capsule Filters
Reverse: 3.4 bar (50 psid) at 25 °C 3.4 bar (50 psid) at 25 °C, intermittent
Bubble Point at 23 °C ≥ 3450 mbar (50.0 psig) air with water
Opticap® XL and XLT Capsules
Air Diffusion Through a water wet membrane at 23 °C at 2.8 bar (40 psi):
≤ 13.3 cc/min ≤ 10.8 cc/min ≤ 13.3 cc/min ≤ 10.8 cc/min Filters for Final Filtration
Gravimetric Extractables After autoclaving and a 24-hour soak in ASTM® Type 1 reagent grade water at controlled room temperature: Millipak® Final Fill Capsules
≤ 50 mg ≤ 75 mg ≤ 45 mg ≤ 70 mg
M
 illidisk® Barrier Cartridges
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This and Millipak® Barrier Capsules
meets the requirements of USP <85>.
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for Sterile Purified Water after a water flush of:
≤ 5000 mL ≤ 5000 mL Durapore® 0.1 μm & 0.22 μm
Bacterial Retention Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology. Durapore® 0.45 μm
Sterilization May be autioclaved for 3 cycles of 60 cycles of 60 min. May be autoclaved for 6 cycles of 30 min. at 123 °C or
at 123 °C. (Cannot be steam sterilized in-line). steam sterilized for 6 cycles of 30 min. at 123 °C.
Durapore® 5.0 μm
Non-Fiber Releasing Durapore® and Milligard® membranes meet the criteria for a “non-fiber releasing” filter as defined in 21 CFR Multimedia Durapore®
210.3 (b) (6).
Charged Durapore® 0.22 μm
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Multilayer Durapore®
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers. Durapore® CBR 0.1 μm &
European Pressure Equipment This product complies with the European Pressure —
0.2 μm
Directive Equipment Directive, 2014/68/EU of 15 May 2014. This Hydrophobic Durapore®
product has been classified under article 4 § 3 of the
Pressure Vessel Directive. It has been designed and
0.22 μm
manufactured in accordance with sound engineering Hydrophobic-hydrophilic
practice to ensure safe use. In compliance with Article 4
§ 3 of the Directive, 2014/68/EU, this product does not
Durapore® 0.22 μm
bear the CE mark.

Contact Information

53
 2.5 2.5 2.5 2.5 2.5 2.5 2.5 2.5 2.5
35 35 35 35 35 35 35 35 35

1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C
1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C

1SFTTVSF
%SPQ
C
2.0 2.0 2.0 30 2.0 30 2.0 30 2.0 30 2.0 30 2.0 30 2.0 30 30 30

25 25 25 25 25 25 25 25 25
1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5
20 20 20 20 20 20 20 20 20
1.0 1.0 1.0 15 1.0 15 1.0 15 1.0 15 1.0 15 1.0 15 1.0 15 15 15

Durapore® Multimedia Filters Durapore® Family Guide

10 10 10 10 10 10 10 10 10
0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
5 5 5 5 5 5 5 5 5

psi d

psi d

psi d
psi d

psi d

psi d

psi d

psi d

psi d
0.0 0.0 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0 0 0
0 10 20 30 40 0 5010 6020 7030 80400 10
50 20
60 30 0 804010 50 20 60 30 7040 0 80 5010
70 6020 7030 80400 10
50 20
60 30 0 8040 10 50 20 60 30 70 40 080 5010
70 6020 7030 80400 10
50 20
60 30
70 8040 50 60 70 80
'MPX
3BUF
-NJO 'MPX
3BUF
L-NJO 'MPX
3BUF

L /min-NJO 'MPX
3BUF
-NJO 'MPX
3BUF
L/min
-NJO 'MPX
3BUF

L/min-NJO 'MPX
3BUF
-NJO 'MPX
3BUF
L/min
-NJO 'MPX
3BUF
-NJO
Typical Clean Water Flow Rates
L /min L /min /min L/min L/min
Overview
Selection & Applications Guide
Cartridge Filter – Multimedia Durapore® Cartridge Filter – Multimedia Durapore® Cartridge Filter – Multimedia Durapore® Formats
Cartridge Filter with
Cartridge
Multimedia
Filter Durapore®
with
Cartridge FilterCartridge
Multimedia with Filter with
Durapore®
Multimedia Cartridge
Multimedia
Durapore®Filter Durapore®
with
Cartridge
Multimedia
Filter Cartridge
with
Durapore®
Multimedia
Filter with
Durapore®
Cartridge
Multimedia
Filter Durapore®
with
Cartridge
Multimedia
Filter with
0.5/0.22 μm (CV06)
0.5/0.22 μm (CV06) 0.5/0.22 μm (CV06)
1.2/0.22
1.2/0.22 μm (CV19)
0.5/0.22 μm (CV06)
µm (CV19)
1.2/0.22 μm (CV19) 1.2/0.22 μm (CV19)
0.5/0.2/0.22 μm (CVSS)
0.5/0.2/0.22
0.5/0.2/0.22 μm (CVSS)
µmDurapore®
Multimedia Durapore®
(CVSS)
0.5/0.2/0.22 μm (CVSS)
OptiScale® Capsules
gpm gpm gpm gpm gpm gpm gpm gpm gpm

1.6
0 5 10 0
1.6
15 5 20 10 0
1.6
15 5
1.4
20
0 10 5 15 10 200
1.4
15 5 20 10 0
1.4 20
15 5
2.5
20
0 10
20
5 15 10200
2.5 20
15 5 20 10 0
2.5
15 5 20 10 15 20
Cartridge Filters
35 35 35
1.4 1 0 - i n . C a r 1.4
20-in. Cartridge
tridge 1 0 - i n . C a 1.4
20-in. Cartridge
r t r i20
dge 1 0 - i n . C a r t r i d20
1.2
20-in. Cartridge
ge 1 0 - i n . C a r t r i d g e 20
20-in. Cartridge
1.2
10-in. Cartridge
1.2
20-in. Cartridge
10-in. Cartridge
2 0 - i n 2.0
. Cartridge
10-in. Cartridge
2 0 - i n . C a r 2.0
tridge
10-in. Cartridge
r t r i30
2 0 - i n . C a 2.0 dge
10-in. Cartridge
2 0 - i n . C a r t r i d30
ge 30 Cartridges
1.2 3 0 - i n . C a r 1.2
tridge 3 0 - i n . C a 1.2
rtridge 30-in. Cartridge 30-in. Cartridge 3 0 - i n . C a r t r i15
dge 3 0 - i n . C a r t r i d15
ge 3 0 - i n . C a r t r i d g e 15 30-in. Cartridge 30-in. Cartridge
1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS

1SFTTVSF
%SPQ
CBS
1.0 1.0 1.0
1.0 1.0 1.0
15 15 15
1.5 1.5
25
1.5
25 25
Optiseal® Cartridges
0.8 0.8 0.8 20 20 20

Millidisk® Cartridges
0.8 0.8 0.8 10 10 10
10 0.6 10 0.6 10 0.6
0.6 0.6 0.6 1.0 1.0 1.0 15 15 15

0.4 0.4 0.4 10 10 10

0.4 0.4 0.4 5 5 5
5 5 5
0.5 0.5 0.5
0.2 0.2 0.2 0.2 0.2 0.2 5 5 5
Capsule Filters
psi d

psi d

psi d

psi d

psi d

psi d

psi d

psi d

psi d
0.0 0.0 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0 0 0
0
L /min
10 20 30
'MPX
3BUF
-NJO
L /min
40 0 5010 6020 7030 80400
'MPX
3BUF
L-NJO
/min
50
10 20
60
'MPX
3BUF

30 0 804010 50 20 60 30 7040 080 5010
70
L /min-NJO 'MPX
3BUF
-NJO
L/min
6020 7030 80400
'MPX
3BUF
L/min
-NJO
50
10 20
60
'MPX
3BUF

L/min-NJO
30 0 8040 10 50 20 60 30 70 40 080 5010
70
'MPX
3BUF
-NJO
L/min
6020 7030 80400
'MPX
3BUF
L/min
-NJO
50
10 20
60 30
70 8040
'MPX
3BUF
-NJO
50 60 70 80
Opticap® XL and XLT Capsules
Typical Clean
Typical
WaterClean
Flow
Typical
Water
Rates
Clean
FlowWater
RatesFlow Rates
Typical Clean
Typical
WaterClean
Flow
Typical
Water
Rates
Clean
FlowWater
RatesFlow Rates Filters for Final Filtration
Opticap XL 10 Capsule — Multimedia
® ®
Opticap XL 10 Capsule — Multimedia Opticap® XL 10 Capsule — Multimedia
Opticap
Durapore ® XL 10 Capsule
0.2/0.22Opticap
with
μmXLMultimedia
10 Capsule
(KV03)Opticap
with
XL Multimedia
10 Opticap
Capsule XL
with
10Multimedia
Capsule
Opticap
Durapore with
® XLMultimedia
10 Capsule
0.5/0.22Opticap
with
μm XL Multimedia
10 Capsule
Opticapwith
(KV06) Multimedia
XL 10 Capsule
Opticap
with
XL Multimedia
10 Capsule
DuraporeOpticap
®with
XL Multimedia
10 Capsule μm
1.2/0.22 with Multimedia
(KV19)
Opticap® XL Legends
Durapore® Opticap®
Refer to
XL Capsule
Legends
Opticap®
Connection
Refer XL
to Legends
Capsule
Type Connection
Refer to Capsule
Type Connection Type Millipak® Final Fill Capsules
Opticap XL —100.2/0.22
Durapore®
Capsule
Opticap μm
with (KV03)
XL —100.2/0.22
MultimediaDurapore®
Capsule
Opticap μm
with(KV03)
XL —Multimedia
100.2/0.22
Capsuleμm
Durapore®
Opticap with
XL
(KV03)
—10
0.5/0.22
Durapore®
Multimedia
Capsule
Opticapμm
with (KV06)
XL —100.5/0.22
Durapore®
Multimedia
Capsule
Opticap μm (KV06)
with
XL —Multimedia
100.5/0.22
Opticapμm
Durapore®
Capsule with(KV06)
XL — 1.2/0.22
Durapore®
10Multimedia
Capsule
Opticap μm
with (KV19)
XL —101.2/0.22
Durapore®
Multimedia
Capsule
Opticapμm (KV19)
with
XL —Multimedia
101.2/0.22
Capsuleμm (KV19)
with Multimedia
Durapore®
TT = 38 — 0.2/0.22
Durapore®
gpmmm (11⁄2 in.)
μm
TT =Sanitary
38 (KV03)
—(11⁄2
0.2/0.22
gpm mm Flange
Durapore®
TT
in.)
Inlet μm
=Sanitary
38
gpmand
mm(KV03)
—(11⁄2
0.2/0.22
Durapore®
Outlet
Flange μmand
in.)Inlet
gpm —(KV03)
0.5/0.22
Sanitary Durapore®
Outlet
Flange μm
gpm (KV06)
Inlet — 0.5/0.22
and Durapore®
Outlet μm (KV06)
gpm — 0.5/0.22 gpmμm —
Durapore® (KV06)
1.2/0.22
Durapore®
μm
gpm (KV19)
— 1.2/0.22
Durapore®
μm (KV19)
gpm — 1.2/0.22 μm (KV19) M
 illidisk® Barrier Cartridges
FF =3.519
0
gpm
mm (3⁄4
5
in.)
FF Sanitary
= 10 19
0
3.5 gpm
mmFlange
(3⁄4 in.)
15 5
FF
Inlet
=Sanitary
19
20 10 0
and
3.5 50gpm
mm Outlet
Flange
(3⁄4 in.)
15 5
Inlet
0Sanitary
20 10 and 5Outlet
3.0 gpm 50
Flange3.0
15
Inlet
10200
and15 Outlet
gpm50
5 20 10 0
3.0 gpm
40
15 5 20010
3.0 gpm
40
515 20 0
10
3.0 gpm
40
15 5 20 10 0
3.0 gpm
15 5 20 10 15 20
and Millipak® Barrier Capsules
HH 3.5
= 014 mm (9⁄16
3.0
5
TT HH
in.)3.0
=Hose
10
3.5
014 mm
Barb
15 (9⁄16
T T Outlet
5 HHin.)
20 =10Hose
3.0
3.5
014 mm
45 Barb
15(9⁄16
T T Outlet
5 in.)
0 10Hose 5Barb
20
45 TT
15 Outlet
10 200
45
15 5
TT
20 10 0 15 5
TT 3.0
20010 515
TT
1020 0
3.0
15 5
TT
20 10 40
3.0
0 15 5
TT
20 10 40 15 20 40
50 50 3.0
2.53.0
2.5 50 3.0
2.5 2.5 2.5 2.5
FF FF FF FF FF 40 FF 40 FF 40 FF FF
40 40 40
HH
TT HH
TT 45 HH
TT 45 HH
TT 45 HH
TT HH
TT HH
TT HH
TT 40 HH
TT 40 40
3.0
2.5 3.0
2.5 3.0
2.5 30 30 30
CBS CBS

CBS CBS

CBS CBS

CBS CBS

CBS CBS

CBS CBS
CBS CBS

CBS CBS

CBS CBS
35 35 2.52.5 35 2.5 2.5 2.5 2.5 30
Durapore® 0.1 μm & 0.22 μm
FF FF FF FF 2.02.0 FF 2.0 FF 2.0 FF 2.0 FF 2.0 FF 30 30
40 40 40
HH HH HH HH HH HH
1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

HH HH HH

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

2.0
2.5 2.0
2.5 2.5 30
2.0 30 30 30 30 30
35 2.0 35 2.0 35 2.0 2.0 2.0 2.0 30 30 30
25 1.5 25 1.5 25 1.5 1.5 1.5 1.5
Durapore® 0.45 μm
20 20 20
1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

2.0
1.5 2.0
1.5 2.0 30
1.5 30 30 20 20 20
20 20 20
25 1.5
1.0 25 1.5
1.0 25 1.5 20
1.0 1.5
1.0 20 1.5
1.0 20 1.5
1.0
1.5
1.0 1.5
1.0 1.5 15
1.0 15 15 20 20 20
20
10 1.0
0.5
20
10 1.0
0.5
20
10 1.0
0.5
10
1.0
0.5
10
1.0
0.5
10
1.0
0.5
10 10 10 Durapore® 5.0 μm
1.0
0.5 1.0
0.5 1.0 15
0.5 15 15
5 5 5 10 10 10
Multimedia Durapore®
10 10 10
10 10 10
psi d psi d

psi d psi d

psi d psi d

psi d psi d

psi d psi d

psi d psi d
psi d psi d

psi d psi d

psi d psi d
0.5
0.0 0.5
0.0 0.5
0.0 0 0.5
0.0 0 0.5
0.0 0 0.5 0
0.0 0.5
0.0 0 0.5
0.0 0 0.5 0
0.0 0 0
0 10 20 30 400 5010 20 7030 804005
60 10
50 20
60 70 5 510
30 0 8040 10 50 20 60 30 70 400 80 50 20
60 80400
7030 50
10 20
60 30 08040 10 50 20 60 30 70 40080 5010
70 20
60 80400
7030 50
10 20
60 8040
30
70 50 60 70 80
6 6 6
0.0 L /min
0 10 20
'MPX
3BUF

0.0 -NJO
L /min
30 40 0 5010
'MPX
3BUF

0.0 L0-NJO
6020 7030 80400
/min
10
50 20
60
'MPX
3BUF

0.0 L /min-NJO
0 'MPX
3BUF
-NJO
0.0 L/min 0
30 0 804010 50 20 60 30 7040 0 80 5010
70
'MPX
3BUF
0-NJO
0.0 L/min
6020 7030 80400 10
50 20
60
0.0 L/min0
'MPX
3BUF
-NJO 'MPX
3BUF
-NJO
0.0 L/min
0
30 0 8040 10 50 20 60 30 70 40 080 5010
70
'MPX
3BUF

6020 7030 80400
0-NJO
0.0 L/min
50
10 20
60 30 8040
70
0
'MPX
3BUF
-NJO
50 60 70 80
0
Charged Durapore® 0.22 μm
L /min 'MPX
3BUF
-NJO
L /min 'MPX
3BUF
L-NJO
/min 'MPX
3BUF

L /min-NJO 'MPX
3BUF
-NJO
L/min 'MPX
3BUF
L/min
-NJO L/min-NJO
'MPX
3BUF
'MPX
3BUF
-NJO
L/min 'MPX
3BUF
L/min
-NJO 'MPX
3BUF
-NJO
Opticap XL 10
10 Capsule
Opticap
with
XLMultimedia
10 Capsule
Opticap
with 10 Opticap
Capsule XL
XL Multimedia with10Multimedia
Capsule
Opticap
® with
XLMultimedia
10 Capsule
Opticap
with
XL Multimedia
10 Multilayer Durapore®
Opticap ®
XL Capsule — Multimedia Opticap XL 10 Capsule — Capsule
Opticapwith
XL 10
Multimedia Multimedia
Capsule
Opticap
with
XL Multimedia
10 Capsule
Opticap Opticap
® with
XLXL10
Multimedia
10 Capsule
Capsule with Multimedia
— Multimedia
Durapore®
® XL —
101.2/0.5/0.22
Durapore®μm—10
(KVSC)
1.2/0.5/0.22
Durapore®μm Durapore®
—Multimedia
10(KVSC)
1.2/0.5/0.22 —10
μm0.5/0.2/0.22
Durapore®
(KVSC) μm
—10
(KVSS)
0.5/0.2/0.22
Durapore®μm—Multimedia
(KVSS)
0.5/0.2/0.22
Durapore®XL —
μm1.2/0.2/0.22
(KVSS)
Durapore®μm—10
(KVSX)
1.2/0.2/0.22
Durapore®μm—Multimedia
10(KVSX)
1.2/0.2/0.22 μmMultimedia
(KVSX)
Durapore
Opticap 1.2/0.5/0.22
Capsule
Opticap
with
XL μmCapsule
(KVSC)
Multimedia
Opticap
with
XL Opticap
CapsuleXLDurapore
with Capsule
Opticap
with
Multimedia 0.5/0.2/0.22
® XLMultimedia
Capsule
Opticap
with
XL μm
10 (KVSS)
Capsule
Opticap with10Multimedia
Capsule
Opticap Durapore
with
XLMultimedia
Capsule
Opticap
®
1.2/0.2/0.22
with
XL Capsule with μm (KVSX) Durapore® CBR 0.1 μm &
Durapore®
gpm — 1.2/0.5/0.22
Durapore®
gpm μm
—(KVSC)
1.2/0.5/0.22
Durapore®
gpm μm Durapore®
— (KVSC)gpm —μm
1.2/0.5/0.22 0.5/0.2/0.22
Durapore®
(KVSC) gpm μm
—(KVSS)
0.5/0.2/0.22
Durapore®
gpm μm
— (KVSS)
0.5/0.2/0.22
Durapore®
gpm —
μm1.2/0.2/0.22
(KVSS)
Durapore®
gpm μm
—(KVSX)
1.2/0.2/0.22
Durapore®
gpm μm
— (KVSX)
1.2/0.2/0.22 μm (KVSX)
0 5 10 0 15 5 0 10
20 5 15 20 10 010200 15 5 20 10 0 15 5 15 5 20010 515 10200 15 5 20 10 0 15 5 20 10 15 20 0.2 μm
3.5 gpm 3.5 gpm 3.5 gpm 50 3.5 gpm 50
gpm
3.5 50 gpm
3.5 50 3.5 gpm 50 3.5 gpm50 gpm
3.5 50 50 50

3.0
3.5
0 5
TT
FF
10 0
3.0
3.5
15 5
T
FF
T
20 10 0
3.0
45
3.5 50
15 5
T
FF
T 3.0
3.5
0 10
20
45
50
5 15
T
FF
T
10 200
3.0
3.5
45
50
15 5
T
FF
T
20 10 0
3.0
45
3.5 50
15 5
T
FF
T
3.0
3.5
20
0 10
45
50
5 15
TT
FF
10200
3.0
3.5
45
50
15 5
T
FF
T
20 10 0
3.0
45
3.5 50
15 5
T
FF
T
20 10
45
50
15 20
45
50
Hydrophobic Durapore®
0.22 μm
40 40 40 40 40 40 40 40 40
THH
T HH
T T 45 HH
T T 45 HH
T T 45 HH
T T 45 HH
T T 45 THH
T 45 HH
T T 45 HH
T T 45 45
3.0
2.5 3.0
2.5 3.0
2.5 3.0
2.5 3.0
2.5 3.0
2.5 3.0
2.5 3.0
2.5 3.0
2.5
CBS CBS

CBS CBS

CBS CBS
CBS CBS

CBS CBS

CBS CBS

CBS CBS

CBS CBS

FF FF 35 FF 35 FF 35 FF 35 FF 35 FF 35 FF 35 FF 35 CBS CBS 35
40 40 40 40 40 40 40 40 40
HH HH HH
1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

HH HH HH HH HH HH
1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

2.5 30
Hydrophobic-hydrophilic
2.0
2.5 2.0
2.5 2.5 30
2.0 2.0
2.5 30 2.0
2.5 30 2.0 2.0
2.5 30 2.0
2.5 30 2.5 30
2.0 30 30
35 35 35 35 35 35 35 35 35
25 25 25 25 25 25 25 25 25
1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

1SFTTVSF
%SPQ

30 30 30
Durapore® 0.22 μm
2.0
1.5 2.0
1.5 2.0
1.5 30 2.0
1.5 30 2.0
1.5 30 2.0
1.5 2.0
1.5 2.0
1.5 2.0
1.5 30 30 30
20 20 20 20 20 20 20 20 20
25 25 25 25 25 25 25 25 25
1.5
1.0 1.5
1.0 1.5
1.0 15 1.5
1.0 15 1.5
1.0 15 1.5
1.0 15 1.5
1.0 15 1.5
1.0 15 1.5
1.0 15 15 15
20 20 20 20 20 20 20 20 20
10 10 10 10 10 10 10 10 10
1.0
0.5 1.0
0.5 1.0 15
0.5 1.0
0.5 15 1.0
0.5 15 1.0 15
0.5 1.0
0.5 15 1.0
0.5 15 1.0 15
0.5 15 15
5 5 5 5 5 5 5 5 5

Contact Information
10 10 10 10 10 10 10 10 10
psi d psi d

psi d psi d

psi d psi d
psi d psi d

psi d psi d

psi d psi d

psi d psi d

psi d psi d

psi d psi d
0.5
0.0 0.5
0.0 0.5 0
0.0 0.5
0.0 0 0.5
0.0 0 0.5 0
0.0 0.5
0.0 0 0.5
0.0 0 0.5 0
0.0 0 0
0 10 20 30 400 5010 60 20 7030 804005 10
50 20
60 70 5 50 20 60 30 70 400 80 50
30 0 8040 10 510 6020 7030 804005 10
50 20
60 30 08040 510 50
70 20 60 30 70 40080 55010 60 20 7030 804005 10
50 20
60 30 8040 5 50
70 60 70 80 5
0.0 L /min 'MPX
3BUF

0.0 -NJO
L /min 'MPX
3BUF

0.0 L0-NJO
/min 'MPX
3BUF

0.0 L /min-NJO
0 'MPX
3BUF

0.0 -NJO
L/min0 'MPX
3BUF
0-NJO
0.0 L/min 'MPX
3BUF

0.0 L/min -NJO
0 'MPX
3BUF

0.0 -NJO
L/min0 'MPX
3BUF
0-NJO
0.0 L/min 'MPX
3BUF
-NJO
0 0
0 10 20 30 40 0 5010 6020 7030 80400 10
50 20
60 30 0 804010 50 20 60 30 7040 0 80 5010 6020 7030 80400
70 10
50 20
60 30 0 8040 10 50
70 20 60 30 70 40 080 5010 6020 7030 80400 10
50 20
60 30 8040
70 50 60 70 80
L /min 'MPX
3BUF
-NJO
L /min 'MPX
3BUF
L-NJO
/min 'MPX
3BUF

L /min-NJO 'MPX
3BUF
-NJO
L/min 'MPX
3BUF
L/min
-NJO 'MPX
3BUF

L/min-NJO 'MPX
3BUF
-NJO
L/min 'MPX
3BUF
L/min
-NJO 'MPX
3BUF
-NJO

Opticap ®
XL Legends
Cartridge Filter with Refer
Cartridge
Multimediato Capsule
Filter Durapore®
with
Cartridge Connection
FilterCartridge
Multimedia with
Durapore® Typewith
Filter
Multimedia Cartridge
Multimedia
Durapore® Filter Durapore®
with
Cartridge
Multimedia
Filter with
Cartridge
Durapore®
Multimedia
Filter with
Durapore®
Cartridge
Multimedia
Filter Durapore®
with
Cartridge
Multimedia
Filter with
Durapore®
Multimedia Durapore®
0.5/0.22
Cartridge μm (CV06)
Filter 0.5/0.22
with
Cartridge μm
Multimedia (CV06)
Filter 0.5/0.22
Durapore®
with
Cartridge μm
Multimedia (CV06)
Filter 1.2/0.22
Cartridge
with
Durapore® μm (CV19)
Filter
Multimedia 1.2/0.22
with
Cartridge μm
Multimedia
Durapore® (CV19)
Filter 1.2/0.22
Durapore®
with
Cartridge μm
Multimedia (CV19)
Filter 0.5/0.2/0.22
Cartridge
with
Durapore®
Multimediaμmwith
Filter (CVSS)
0.5/0.2/0.22
Durapore®
Cartridge
Multimedia μmDurapore®
Filter (CVSS)
0.5/0.2/0.22
with
Cartridge
Multimediaμmwith
Filter (CVSS)
Durapore®
Multimedia Durapore®
TT = 38 mm (1½ in.) Sanitary Flange Inlet and Outlet
0.5/0.22
gpm μm (CV06) 0.5/0.22
gpm μm (CV06) 0.5/0.22gpm μm (CV06)1.2/0.22
gpm μm (CV19) 1.2/0.22gpm μm (CV19) 1.2/0.22gpm μm (CV19) 0.5/0.2/0.22 μm (CVSS)
0.5/0.2/0.22 μm (CVSS)
0.5/0.2/0.22 μm (CVSS)
54
gpm gpm gpm
FF = 19 mm 0
(¾ 5in.) Sanitary
10 0
Flange
15 5
Inlet and
20 10 0 15 5
Outlet
20
0 10 5 15 10200 15 5 20 10 0 15 5 20010 515 10200 15 5 20 10 0 15 5 20 10 15 20
1.6 gpm 1.6 gpm 1.6 gpm 1.4 gpm 1.4 gpm gpm
1.4 20 2.5 gpm 20 2.5 gpm20 2.5 gpm
HH = 14 mm 0
(⁹⁄₁₆5
in.) 10Hose
0
Barb
15 5
Inlet
20 10 0
and 15Outlet
5 20
0 10 5 15 10 200 15 5 20 10 0 15 5 200 10 5 15 10200 15 5
35
20 10 0 15 5 20 10
35
15 20
35
1.4 10-in. C a r1.4tridge 1 0 - i n . C a 1.4
r t r i 20
dge 1 0 - i n . C a r t r i d20 ge 10-in. C a r t r i d g e 20 10-in. Cartridge 10-in. Cartridge 10-in. Cartridge 10-in. Cartridge 10-in. Cartridge
1.6 1.6 1.6 1.4
1.2 1.4
1.2 1.4
1.2 2.5 2.5 2.5
20-in. Cartridge 20-in. Cartridge 20-in. Cartridge 20-in. Cartridge 2 0 - i n . C a r t r i 20dge C a r t r i d20
2 0 - i n . 2.0 ge 20-in. C a r2.0 t r i d g e 20 2 0 - i n . C a 2.0 30
r t r i 35
dge 2 0 - i n . C a r t r i d30 35
ge 30
35
1.2
1.4 13 00 -- ii nn .. C aa rr1.2
C tt rr ii dd gg ee
1.4 3100--iinn. . CCaa1.2
r1.4
rttrrii20
ddggee 3100--iinn. . CCaarrttrriidd20
ggee 13 00 -- ii nn .. C aa rr tt rr ii dd gg ee 20
C 3100--iinn. . CCaarrttrrii15
ddggee 3100--iinn. . CCaarrttrriid15
dggee 13 00 -- ii nn .. C aa rr tt rr ii dd gg ee 15
C 3100--iinn. . CCaarrttrriiddggee 3100--iinn. . CCaarrttrriiddggee
PQ
CBS

PQ
CBS

PQ
CBS

S CBS

S CBS

S CBS

S CBS

S CBS

S CBS

1.2 1.2 1.2

20-in. Cartridge 2 0 - i n . C a r t r i15 dge 2 0 - i n1.0
. C a r t r i 15
dge 20-in.
1.0
C a r t r i d g e 15 20-in. Cartridge
1.0
2 0 - i n 2.0
. Cartridge 20-in. C a r 2.0tridge 2 0 - i n . C a 2.0 25
r t r i30
dge 2 0 - i n . C a r t r i 25d30
ge 25
30
1.0
1.2 30-in. C a r1.0 tridge
1.2 3 0 - i n . C a1.0rtridge
1.2 30-in. Cartridge 30-in. Cartridge 3 0 - i n . C a r t r i15 dge 3 0 - i n 1.5
. C a r t r i d15ge 30-in. C a r1.5 t r i d g e 15 3 0 - i n . C a1.5rtridge 30-in. Cartridge
PQ

PQ

PQ

PQ

PQ

PQ

BS

BS

BS

0.8 0.8 0.8

Durapore® Multimedia Filters Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
OptiScale® Capsule Filters
OptiScale® Capsules
Cartridge Filters
S V A Cartridges
Optiseal® Cartridges
Media Type May be Disc Size (mm) Quantity per pkg. Millidisk® Cartridges
Autoclaved
V = Durapore ® 25 = 25 mm 3 = 3/pk
47 = 47 mm 6 = 6/pk
Capsule Filters
OptiScale ®
Media Pore Sizes Connection Type Opticap® XL and XLT Capsules
Capsule Filter
Multimedia: Milligard® (nominal)/ For 25 mm size only
Durapore® NB = Female Luer-Lok™ Inlet/Male Luer Slip Outlet Filters for Final Filtration
03 = 0.2 μm/0.22 μm
For 47 mm size only
06 = 0.5 μm/0.22 μm Millipak® Final Fill Capsules
HH = 6 mm (¼ in.) Hose Barb Inlet and Outlet
19 = 1.2 μm/0.22 μm
FF = 19 mm (¾ in.) Sanitary Flange Inlet and Outlet M
 illidisk® Barrier Cartridges
Multimedia: Milligard (nominal)/
®
FH = 19 mm (¾ in.) Sanitary Flange Inlet and and Millipak® Barrier Capsules
Milligard® (nominal)/Durapore®
6 mm (¼ in.) Hose Barb Outlet
SC = 1.2 μm/0.5 μm/0.22 μm
SS = 0.5 μm/0.2 μm/0.22 μm Durapore® 0.1 μm & 0.22 μm
SX = 1.2 μm/0.2 μm/0.22 μm
Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Cartridge Filters
Multilayer Durapore®
Durapore® CBR 0.1 μm &
C V T P 3 0.2 μm
Hydrophobic Durapore®
0.22 μm
Cartridge Media Type Cartridge Code Cartridge Length Quantity per pkg.
Filter Hydrophobic-hydrophilic
V = Durapore® 0 = (2-222) O-ring 1 = 10-inch 3 = 3/pk
7 = ( 2-226) O-ring with 2 = 20-inch
Durapore® 0.22 μm
locking tab and spear 3 = 30-inch
Media Pore Sizes
Contact Information
Multimedia: Milligard® (nominal)/ Multimedia: Milligard® (nominal)/
Durapore® Milligard® (nominal)/Durapore®
03 = 0.2 μm/0.22 μm SC = 1.2 μm/0.5 μm/0.22 μm
06 = 0.5 μm/0.22 μm SS = 0.5 μm/0.2 μm/0.22 μm
19 = 1.2 μm/0.22 μm SX = 1.2 μm/0.2 μm/0.22 μm

55
Durapore® Multimedia Filters Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Opticap® XL Capsule Filters
OptiScale® Capsules
Cartridge Filters
K V A 1 0 1 Cartridges
Optiseal® Cartridges
Media Type May be Disc Size (mm) Quantity per pkg. Millidisk® Cartridges
Autoclaved
V = Durapore ® 10 = Opticap XL 10
®
1 = 1/pk

Media Pore Sizes Capsule Filters

Opticap XL
®
Multimedia: Milligard® Connection Type Opticap® XL and XLT Capsules
Capsule Filter (nominal)/Durapore® TT = 38 mm (1 1/2 in.) Sanitary Flange Inlet and Outlet
03 = 0.2 μm/0.22 μm FF = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet
06 = 0.5 μm/0.22 μm
Filters for Final Filtration
HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet
19 = 1.2 μm/0.22 μm Millipak® Final Fill Capsules
Multimedia: Milligard (nominal)/
®
M
 illidisk® Barrier Cartridges
Milligard® (nominal)/Durapore® and Millipak® Barrier Capsules
SC = 1.2 μm/0.5 μm/0.22 μm
SS = 0.5 μm/0.2 μm/0.22 μm
SX = 1.2 μm/0.2 μm/0.22 μm Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

56
Filters Containing Charged Durapore ® Durapore® Family Guide

0.22 μm Membrane Overview

Selection & Applications Guide
For sterile filtration, endotoxin removal and low preservative adsorption Formats
OptiScale® Capsules
Filters containing charged Durapore®
Cartridge Filters
0.22 μm membrane are designed for sterile
Cartridges
filtration and endotoxin removal from
pharmaceutical-grade water systems. These Optiseal® Cartridges
filters are manufactured from 0.22 μm Millidisk® Cartridges
hydrophilic polyvinylidene fluoride (PVDF)
membrane modified to have a net positive Capsule Filters
charge which enables binding of negatively Opticap® XL and XLT Capsules
charged endotoxins that would otherwise
pass through 0.22 μm sterilizing-grade filters. Filters for Final Filtration
Charged Durapore® filters reduce adsorptive Millipak® Final Fill Capsules
loss of positively charged preservatives and M
 illidisk® Barrier Cartridges
quartenary amines. and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Benefits Typical water flow rate at 23 °C
Durapore® 0.45 μm
• Positively charged membrane that removes negatively Flow Rate (L/min) Durapore® 5.0 μm
charged species such as endotoxins and minimizes 0 10 20 30 40 50 60 70
adsorption of quaternary amines and other positively 20 1.4 Multimedia Durapore®
charged preservatives 18
Charged Durapore® 0.22 μm
16
• Low protein binding membrane yields high protein Multilayer Durapore®

Differential Pressure (bar)

14
Differential Pressure (psi)

recovery with minimal product loss Durapore® CBR 0.1 μm &

12

• Broad chemical compatibility, low extractables 10 0.7

0.2 μm
8 Hydrophobic Durapore®
• For filtration processes requiring high flow rates and
0.22 μm
throughputs 6

4 Hydrophobic-hydrophilic
Filter Formats 2 Durapore® 0.22 μm
0 0
• Cartridge filters 0 4 8 12 16 20

• Optiseal® cartridge filters

Flow Rate (GPM)
Contact Information

57
Filters Containing Charged Durapore® 0.22 μm Membrane Durapore® Family Guide

Optiseal® Cartridge and Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Optiseal® Cartridge Cartridge (per 10-inch)
Formats
Effective Filtration Area 1.9 ft2 (0.2 m2) per 4-inch (10.2 cm) 7.4 ft2 (0.7 m2)
Optiseal® cartridge OptiScale® Capsules
Materials of Construction Modified polyvinylidene fluoride (PVDF) membrane with a net positive charge. Cartridge Filters
Non-woven polypropylene pleat supports upstream and downstream.
Rigid polypropylene outer sleeve, core, end caps and adapter. Silicone O-rings. Cartridges
Endotoxin Removal Charged Durapore® membrane samples exhibit LRV >5 when challenged with 106 pg/mL of purified Escherichia Optiseal® Cartridges
coli (Type 055:B5 LPS) endotoxins.
Integrity Test Each cartridge must pass our integrity test, which is correlated to the B. diminuta ASTM® bacterial challenge test.
Millidisk® Cartridges
Bacterial Retention Quantitative retention of 107 CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM© F838 methodology.
Capsule Filters
Bubble Point in Water at 23 °C ≥ 2760 mbar (40.0 psig)
Bacterial Endotoxin Aqueous extraction contains <0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This
Opticap® XL and XLT Capsules
meets the requirements of USP <85>.
Thermal Stress Resistance 135 °C, 30 minutes, up to 10 times, Steam-in-Place Filters for Final Filtration
Hydraulic Stress Resistance 80 psid (5.5 bar) at 25 °C in the forward direction Millipak® Final Fill Capsules
50 psid (3.4 bar) at 25 °C in the reverse direction
M
 illidisk® Barrier Cartridges
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. and Millipak® Barrier Capsules
Autoclaved filters are non toxic per USP <88> Safety Test.
Total Organic Carbon (TOC) / Samples exhibited < 500 ppb TOC per USP <643> after sterilization and a WFI water flush of:
Conductivity
2.0 L at 250 mL/min per 4 in. Optiseal® cartridge 5.5 L at 500 mL/min per 10 in. cartridge Durapore® 0.1 μm & 0.22 μm
Non-Fiber Releasing Meets the criteria for a non-fiber releasing filter as defined in the Code of Federal Regulations 21 CFR 210.3 (b) (6). Durapore® 0.45 μm
Air Diffusion in Water at 23 °C ≤ 4.0 cc/min at 30 psid (2.07 bar) in the forward ≤ 10.0 cc/min at 30 psid (2.07 bar) in the forward Durapore® 5.0 μm
direction per 4-inch (10.2 cm) Optiseal® cartridge. direction per 10-inch (25.4 cm) cartridge.
Multimedia Durapore®
Water Flow Rate/Pressure Drop ≤ 8 psid (0.55 bar) at 2 gpm (7.6 Lpm) per 4-inch ≤ 3 psid (0.21 bar) at 2 gpm (7.6 Lpm) per 10-inch
(10.2 cm) Optiseal® cartridge at 23 °C. (25.4 cm) cartridge at 23 °C. Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

58
Filters Containing Charged Durapore® 0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Cartridge Filters Formats
OptiScale® Capsules
Cartridge Filters
C C G L T P 1
Cartridges
Optiseal® Cartridges
Cartridge Pore Size Cartridge Length Quantity per pkg.
Filter
GL = 0.22 μm 1 = 10-inch 1 = 1/pk
Millidisk® Cartridges
2 = 20-inch
Media Type Cartridge Code 3 = 30-inch TP = With prefilter Capsule Filters
C = Charged 0 = (2-222) O-ring Opticap® XL and XLT Capsules
Durapore® 5 = (2-222) O-ring with spear assembly
7 = (2-226) O-ring with locking outlet and spear assembly
Filters for Final Filtration
8 = Concentric O-ring with spear assembly
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Optiseal® Cartridge Filters
Durapore® 0.1 μm & 0.22 μm
L C G L 0 4 T P 6 Durapore® 0.45 μm
Durapore® 5.0 μm

Optiseal® Pore Size Cartridge Length Quantity per pkg.

Multimedia Durapore®
Cartridge
GL = 0.22 μm 4 = 4-inch 6 = 6/pk Charged Durapore® 0.22 μm
Filter
Multilayer Durapore®
Media Type Cartridge Code TP = With prefilter
Durapore® CBR 0.1 μm &
C = Charged 0 = (2-123) O-ring 0.2 μm
Durapore®
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

59
Filters Containing Multilayer Durapore ® Durapore® Family Guide

0.45/0.22 μm Membrane Overview

Selection & Applications Guide
High throughput filters for sterile filtration of challenging streams Formats
OptiScale® Capsules
Filters containing multilayer Durapore®
Cartridge Filters
0.45/0.22 μm hydrophilic polyvinylidene
Cartridges
fluoride (PVDF) membrane provide
sterilizing-grade performance for Optiseal® Cartridges
difficult-to-filter streams. These filters Millidisk® Cartridges
improve process efficiency with high product
recovery, extended throughput and low Capsule Filters
pressure drops. Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Benefits Filter Formats
Durapore® 0.45 μm
• Dual layer filter maximizes product recovery and • OptiScale® capsules
Durapore® 5.0 μm
throughput with low pressure drop
• Cartridge filters Multimedia Durapore®
• Low protein binding membrane yields high protein
• Opticap® XL and XLT capsules Charged Durapore® 0.22 μm
recovery with minimal product loss
Multilayer Durapore®
• Broad chemical compatibility, low extractables
Durapore® CBR 0.1 μm &
• For filtration processes requiring high flow rates 0.2 μm
and throughputs
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

60
Filters Containing Multilayer Durapore® 0.45/0.22 μm Membrane Durapore® Family Guide

OptiScale® Capsule and Cartridge Filter Specifications Overview

Selection & Applications Guide
Description OptiScale® 25 Capsule OptiScale® 47 Capsule Cartridge (per 10-inch)
Formats
Nominal Dimensions
Maximum length: 39 mm (1.52 in.) with female 82 mm (3.24 in.) with flange inlet/ 25.4 cm (10 in.) OptiScale® Capsules
Luer-Lok™ inlet/male luer slip hose barb outlet
outlet 74 mm (2.91 in.) with flange inlet/ Cartridge Filters
flange outlet
94 mm (3.70 in.) with hose barb Cartridges
inlet/hose barb outlet Optiseal® Cartridges
Body Diameter: 31 mm (1.21 in.) 69 mm (2.75 in.) 6.9 cm (2.7 in.)
Weight: 0.19 oz (5.5 g) 2.3 oz (67 g) — Millidisk® Cartridges
Filtration Area 3.5 cm2 17.7 cm2 0.55 m2 (6.0 ft2)
Materials of Construction Capsule Filters
Filter membrane: Dual layer hydrophilic PVDF Dual layer hydrophilic PVDF Dual layer hydrophilic PVDF Opticap® XL and XLT Capsules
Structural components*: Polypropylene Polycarbonate Polycarbonate
Supports: Polypropylene Polypropylene Polycarbonate
Vent cap: Polypropylene PVDF — Filters for Final Filtration
O-rings: — Fluoroelatomers Silicone
Millipak® Final Fill Capsules
Housing Vent Capped vent with female Luer Adjustable vent with male luer and —
connections on inlet side of device. female Luer-Lok™ connections on M
 illidisk® Barrier Cartridges
inlet side of device. and Millipak® Barrier Capsules
Maximum Inlet Pressure 4.1 bar (60 psi) at 25 °C 5.5 bar (80 psi) at 25 °C —
Maximum Differential Pressure
Durapore® 0.1 μm & 0.22 μm
Forward: 4.1 bar (60 psi) at 25 °C — 5.5 bar (80 psid) at 25 °C
Reverse: 0 bar (0 psi) — 1.75 bar (25 psid) at 80 °C Durapore® 0.45 μm
345 mbar (5 psid) at 135 °C
3.4 bar (50 psid) at 25 °C, Durapore® 5.0 μm
intermittent
Multimedia Durapore®
Bubble Point at 23 °C — ≥ 3450 mbar (50.0 psig) air ≥ 3450 mbar (50.0 psig) air
with water with water Charged Durapore® 0.22 μm
Air Diffusion — — Through a water wet membrane at Multilayer Durapore®
2.8 bar (40 psig) at ambient
temperature: ≤ 10.8 cc/min per Durapore® CBR 0.1 μm &
10-inch element 0.2 μm
Bacterial Retention — — Quantitative retention of 107 CFU/ Hydrophobic Durapore®
cm2 Brevundimonas diminuta per
0.22 μm
ASTM® F838 methodology.
Bacterial Endotoxin Aqueous extraction contains < 0.25 — Aqueous extraction contains < 0.25 Hydrophobic-hydrophilic
EU/mL as determined by the Limulus EU/mL as determined by the Limulus Durapore® 0.22 μm
Amebocyte Lysate (LAL) Test. Meets Amebocyte Lysate (LAL) test. Meets
the requirements of USP <85>. the requirements of USP <85>.
Total Organic Carbon (TOC) / Autoclaved filter effluent meets the — Autoclaved cartridges meet the Contact Information
Conductivity WFI requirement of USP <643>, for requirements of USP <643> for Total
Total Organic Carbon and USP <645> Organic Compounds and USP <645>
for Water Conductivity at 25 ºC after for Water Conductivity at 25 ºC after
a WFI flush of 35 mL. a WFI water flush of 16 liters.

61
Filters Containing Multilayer Durapore® 0.45/0.22 μm Membrane Durapore® Family Guide

OptiScale® Capsule and Cartridge Filter Specifications (continued) Overview

Selection & Applications Guide
Description OptiScale® 25 Capsule OptiScale® 47 Capsule Cartridge (per 10-inch)
Formats
Oxidizable Substances — Effluent meets the USP Oxidizable Effluent meets the USP Oxidizable
Substance Test requirements for Substance Test requirements for OptiScale® Capsules
Sterile Purified Water after a water Sterile Purified Water after a water
flush of ≤ 100 mL flush of ≤ 1500 mL per 10-inch Cartridge Filters
element
Cartridges
Sterilization May be autoclaved for 1 cycle of May be autoclaved for 3 cycles of May be autoclaved for 30 cycles of
60 minutes at 123 °C. 60 minutes at 126 °C. 60 minutes at 126 °C or steam Optiseal® Cartridges
sterilized up to 30 times for 30
minutes at 135 °C Millidisk® Cartridges
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
Capsule Filters
information provided by raw material suppliers. Opticap® XL and XLT Capsules
* Cage, core, end caps and capsule housing
Filters for Final Filtration
Opticap XL and XLT Autoclavable Capsule Filter Specifications
® Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
Description Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30
and Millipak® Barrier Capsules
Nominal Dimensions
Maximum length: 33.5 cm (13.2 in.) 37.6 cm (14.8 in.) 62.5 cm (24.6 in.) 87.1 cm (34.3 in.)
Body diameter: 10.7 cm (4.2 in.) — — — Durapore® 0.1 μm & 0.22 μm
Fitting to Fitting Durapore® 0.45 μm
Sanitary flange to sanitary flange: — 15.2 cm (6.0 in.) 15.2 cm (6.0 in.) 15.2 cm (6.0 in.)
Sanitary flange to hose barb: — 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) Durapore® 5.0 μm
Hose barb to hose barb: — 19.8 cm (7.8 in.) 19.8 cm (7.8 in.) 19.8 cm (7.8 in.)
Multimedia Durapore®
Filtration Area 0.55 m2 (6.0 ft2) 0.55 m2 (6.0 ft2) 1.1 m2 (12 ft2) 1.65 m2 (18 ft2)
Charged Durapore® 0.22 μm
Materials of Construction
Filter membrane: Dual layer hydrophilic PVDF Multilayer Durapore®
Supports: Polypropylene Durapore® CBR 0.1 μm &
Structural components*: Polypropylene
Vent O-rings: Silicone
0.2 μm
Vent/Drain /4 in. hose barb with double O-ring seal; connects to 1/8 in. tubing
1 Hydrophobic Durapore®
0.22 μm
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C
2.8 bar (40 psi) at 60 °C Hydrophobic-hydrophilic
1.0 bar (15 psi) at 80 °C Durapore® 0.22 μm
Maximum Differential Pressure
Forward: 5.5 bar (80 psid) at 25 °C, 1.75 bar (25 psid) at 80 °C
Reverse: 3.5 bar (50 psid) at 25 °C, intermittent Contact Information
Bubble Point at 23 °C ≥ 3450 mbar (50.0 psig) air with water
Air Diffusion Through a water wet membrane at 2.8 bar (40 psig) at ambient temperature:
≤ 10.8 cc/min ≤ 10.8 cc/min ≤ 21.6 cc/min ≤ 32.4 cc/min

62
Filters Containing Multilayer Durapore® 0.45/0.22 μm Membrane Durapore® Family Guide

Opticap® XL and XLT Autoclavable Capsule Filter Specifications (continued) Overview

Selection & Applications Guide
Description Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30
Formats
Total Organic Carbon (TOC) / Autoclaved filter effluent meets the WFI requirements of USP <643> for Total Organic Carbon and USP <645>
Conductivity for Water Conductivity at 25 ºC after a WFI water flush of: OptiScale® Capsules
16 L 16 L 32 L 48 L
Cartridge Filters
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for Sterile Purified Water after a water flush of:
≤ 1500 mL ≤ 1500 mL ≤ 3000 mL ≤ 4500 mL Cartridges
Bacterial Endotoxin Aqueous extraction contains < 0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This Optiseal® Cartridges
meets the requirements of USP <85>.
Millidisk® Cartridges
Bacterial Retention Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology.
Sterilization May be autoclaved for 3 cycles of 60 minutes at 126 °C. (Cannot be steam sterilized in-line.)
Capsule Filters
Non-Fiber Releasing Durapore® membrane meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Opticap® XL and XLT Capsules
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers. Filters for Final Filtration
*Cage, core, end caps, and capsule housing Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
Opticap® XL and XLT Sterile and Gamma-Compatible Capsule Filter Specifications and Millipak® Barrier Capsules

Description Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30

Durapore® 0.1 μm & 0.22 μm
Nominal Dimensions
Maximum length: 33.5 cm (13.2 in.) 37.6 cm (14.8 in.) 62.5 cm (24.6 in.) 87.1 cm (34.3 in.) Durapore® 0.45 μm
Body diameter: 10.7 cm (4.2 in.) — — —
Durapore® 5.0 μm
Fitting to Fitting
Sanitary flange to sanitary flange: — 15.2 cm (6.0 in.) 15.2 cm (6.0 in.) 15.2 cm (6.0 in.)
Multimedia Durapore®
Sanitary flange to hose barb: — 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) Charged Durapore® 0.22 μm
Hose barb to hose barb: — 19.8 cm (7.8 in.) 19.8 cm (7.8 in.) 19.8 cm (7.8 in.)
Multilayer Durapore®
Filtration Area 0.60 m2 (6.5 ft2) 0.60 m2 (6.5 ft2) 1.2 m2 (13 ft2) 1.81 m2 (19.8 ft2)
Durapore® CBR 0.1 μm &
Materials of Construction
Filter membrane: Dual layer hydrophilic PVDF 0.2 μm
Supports: Polypropylene Hydrophobic Durapore®
Structural components*: Gamma-compatible polypropylene
0.22 μm
Vent O-rings: Silicone
Vent/Drain ¼ in. hose barb with double O-ring seal connects to 1/8 in. tubing
Hydrophobic-hydrophilic
Durapore® 0.22 μm
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C
2.8 bar (40 psi) at 60 °C
1.0 bar (15 psi) at 80 °C
Contact Information
Maximum Differential Pressure
Forward: 5.5 bar (80 psid) at 25 °C, 1.05 bar (15 psid) at 80 °C
Reverse: 3.5 bar (50 psid) at 25 °C, intermittent

63
Filters Containing Multilayer Durapore® 0.45/0.22 μm Membrane Durapore® Family Guide

Opticap® XL and XLT Sterile and Gamma-Compatible Capsule Filter Specifications (continued) Overview
Selection & Applications Guide

Description Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30 Formats

Bubble Point at 23 °C ≥ 3450 mbar (50.0 psig) air with water OptiScale® Capsules
Air Diffusion Through a water wet membrane at 2.8 bar (40 psig) at ambient temperature: Cartridge Filters
≤ 15.0 cc/min ≤ 15.0 cc/min ≤ 30.0 cc/min ≤ 45.0 cc/min
Cartridges
Total Organic Carbon (TOC) / Filter effluent meets the WFI requirements of USP <643> for Total Organic Carbon and USP <645> for Water
Conductivity Conductivity at 25 ºC after a WFI water flush of: Optiseal® Cartridges
36 L 36 L 72 L 108 L
Millidisk® Cartridges
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for Sterile Purified Water after a water flush of:
≤ 1500 mL ≤ 1500 mL ≤ 3000 mL ≤ 4500 mL
Capsule Filters
Bacterial Endotoxin Aqueous extraction contains < 0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This
meets the requirements of USP <85>. Opticap® XL and XLT Capsules
Bacterial Retention Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology.
Sterilization Filters for Final Filtration
Gamma-compatible: Gamma-compatible to 45 kGy. May be autoclaved for 3 cycles of 60 minutes at 123 °C. (Cannot be steam
sterilized in-line.)
Millipak® Final Fill Capsules
Sterile capsules: May be autoclaved for 3 cycles of 60 minutes at 123 °C. (Cannot be steam sterilized in-line.) M
 illidisk® Barrier Cartridges
Sterility (Sterile capsules only) Meets current USP and AAMI guidelines for sterility utilizing a validated sterilization cycle. and Millipak® Barrier Capsules
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. Durapore® 0.1 μm & 0.22 μm
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on Durapore® 0.45 μm
information provided by raw material suppliers.
Durapore® 5.0 μm
*Cage, core, end caps, and capsule housing
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

64
 1.5
1.5 30 1.5 30
2.0 30 2.0

Pressure Dro

Pressure Dro
Dro

Dro
2.0

PressureDro

PressureDro
20
20 20
25
25 25

Pressure

Pressure
1.0 15 1.5
1.5 1.0 15 1.5
1.0 15 20
20 20

10 1.0
1.0 15
15 10 1.0 15
10
0.5 0.5
Filters Containing Multilayer Durapore 0.45/0.22 μm Membrane Durapore Family Guide
10 10
0.5
55 0.5
0.5 ® 10
5 0.5 ®
55 5

psid
psid

psid
psid

psid
psid
0.0
0.0 00 0.0
0.0 00 0.0 0 0.0 0

TYPICAL CLEAN WATER FLOW–RATES: AUTOCLAVABLE

00 10 20 30 40 50 60 80 00 20
20 40
40 60
60 80
80 0 10 20 30 40 50 60 80 0 20 40 60 80
10 20 30 40 50 60 80
Typical Clean
Flow Water
FlowRate
Rate(L/min)
(L/min) Flow Rates Cartridge
Flow and
FlowRate
Rate Autoclavable Capsule Filters
(L/min)
(L/min) Flow Rate (L/min) Overview
Flow Rate (L/min)

Selection & Applications Guide

Cartridge
Opticap XLFilters — Multilayer Durapore® Opticap
Opticap
®
XL
XLT 10 Capsules — Multilayer Opticap
OpticapXLT
®
XL 10 Capsules — Multilayer OpticapFormats
XLT 20 Capsule Filters —
Car
Opticap XL O
Opticap XLT 20
20 Capsule
Capsule Filters
Filters —
—
0.45/0.22 μm Membrane Durapore® 0.45/0.22 μm Membrane Durapore® 0.45/0.22 μm Membrane
0.45/0.22
0.45/0.22µm
0.45/0.22 µmHydrophilic
HydrophilicDurapore
Durapore 0.45/0.22
0.45/0.22µm
µm Hydrophilic
HydrophilicDurapore
Durapore
0.45/0.22 µm Hydrophilic Durapore 0.45/0.22 µm Hydrophilic Durapore 0.45/0.22 µm Hydrophilic Durapore
®
OptiScale Capsules
gpm
gpm
gpm gpmgpm
gpm gpm gpm
00 0 55 5 1010
10 1515
15 20
20
20
3.5
00 0 55 5 10
10 10 15
15 15 20
20 20
4.5
0 5 10 15 20
3.5
0 Cartridge
5 10Filters
15 20
4.5
2.5
4.5 3.53.5 50 50
35 50 50
4.0
4.0 TT
TT
60
60
3.0
3.03.0
TT
TTTT 45
45 45 4.0 TT
60
3.0
Cartridges
TT 45
2.0 HH
HH 30 HH
HHFF HH HH
3.5 50 40
40 40 3.5 50 40
Optiseal® Cartridges

Pressure Drop (bar)

(bar)
3.5
Pressure Drop (bar)

Drop (bar)
TH 50 TH
THHH TH TH

Pressure Drop(bar)

Pressure Drop (bar)

(bar)

TH
Drop(bar)

BB 2.5
2.52.5 BB BB 2.5 BB
3.0
3.0 BB 25 BBTH 35
35 35 3.0 35
1.5 40 40
40
Millidisk® Cartridges

Pressure Drop
30
30 30 30
PressureDrop

2.5 2.0
2.02.0 2.5 2.0
2.5 20
25
25 25 25
2.0 30
30 2.0 30

Pressure
2.0 1.5
1.51.5 1.5
Pressure

1.0 15 20 20
20 20
1.5
1.5 1.5

1.0
20
2010 1.0
1.01.0 15
15 15
1.0
20 1.0 Capsule Filters 15
0.5
1.0 10
10 10 10
0.5
0.5
10
105 0.5
0.50.5
55 5 0.5
10 0.5
Opticap XL and XLT 5Capsules
®

psid

psid
psid
psid

psid
psid

psid
psid

0.0
0.0
0.0 00 0 0.0
0.00.0 00 0 0.0 0 0.0 0

TYPICAL Flow
CLEAN WATER FLOW RATES: AUTOCLAVABLE
00 0 10 20
2020 30 40
4040 50 60
6060 80
8080 00 0 20
20 20 40
40 40 60
60 60 80
80 80 0 20 40 60 80 0 20 40 60 80

Flow Rate
FlowRate(L/min)
Rate(L/min)
(L/min) Flow
FlowRate
Flow (L/min)
Rate
Rate (L/min)
(L/min) Flow Rate (L/min) FiltersFlow
forRate
Final
(L/min)Filtration

Millipak® Final Fill Capsules

Opticap
Car
®
XLT
OpticapXLTXL
20 Capsules — Multilayer Opticap
O
®
Opticap
XLT 30 Capsules — Multilayer
XLT 20 Capsule Filters —
Opticap
Opticap
Durapore XLT
®
0.45/0.22 μm Membrane Durapore® 0.45/0.22 μm Membrane
Opticap XLT M
 illidisk® Barrier Cartridges
0.45/0.22
0.45/0.22
0.45/0.22 µm
0.45/0.22 µm µmHydrophilic
HydrophilicDurapore
µm Hydrophilic
Hydrophilic Durapore
Durapore
Durapore 0.45/0.22 µm
0.45/0.22 µmHydrophilic
HydrophilicDurapore
Durapore 0.45/0.22 µm Hydrophilic Durapore and Millipak® Barrier Capsules
gpm
gpmgpm gpm
gpm gpm
gpm
0000 5555 10
10
10
10
15
15
15
15
2020
20
20
00 55 10
10 15
15 20
20 0 5 10 15 20
2.5
4.5
3.0 3.5
3.5 50
50 3.0
3.0
4.0 TT
TT
35
60
40
40 TT
TT 45
45 TT 40 Durapore® 0.1 μm & 0.22 μm
TT 3.0
3.0
2.5
2.0
2.5 HH
HH 30 FF
HH 2.5 HH
3.5 HH 35
35
50 40
40 35
Durapore® 0.45 μm
(bar)
(bar)

Drop (bar)

TH HH
TH
(bar)

TH
TH TH

Pressure Drop (bar)

Drop(bar)

2.5
2.5
(bar)

BB
BB 25 TH
BB 35
35 BB
3.0
2.0 BB 30
30 2.0 30
2.0 40
Durapore® 5.0 μm
Pressure Drop

1.5 30
Drop

2.0
2.0 30
PressureDrop

2.5 25 25
Drop

20
25
1.5
1.5 25
25 1.5
30
Multimedia Durapore®
Pressure

2.0 20 20
Pressure

20 1.5
1.5
Pressure

1.0 15 20
Pressure

20
1.5
1.0 15
15 1.0 15
1.0 20
1.0
0.5
10
10
1.0
1.0 15
15
10
Charged Durapore® 0.22 μm
10 10
10
0.5
0.5 510 0.5
0.5 0.5
0.5 55 55 psid
psid
5 Multilayer Durapore®
psid
psid

psid
psid

0.0
psid

0.0
0.0 000 0.0
0.0 00 0.0 0
0.0 0
000 10 20
20
20
20 30 40
40
40
40 50 60
60
60
60
80 0
80
80
80
00 20
20 40
40 60
60 80
80 0 20 40 60 80 Durapore® CBR 0.1 μm &
FlowRate
Rate(L/min)
(L/min) Flow Rate
Flow Rate (L/min)
(L/min)
Flow
Flow
Flow Rate
Rate (L/min)
(L/min) Flow Rate (L/min) 0.2 μm
Hydrophobic Durapore®
Opticap
Opticap XL
XLT Opticap XLT 20 Capsule Filters — 0.22 μm
Opticap®
XL Capsule
0.45/0.22
0.45/0.22 µm LegendsDurapore
µm Hydrophilic
Hydrophilic Refer
Durapore Opticap XLT Capsule
0.45/0.22
®
Legends
µm Hydrophilic Refer
Durapore
to Connection Type to Connection Type Hydrophobic-hydrophilic
gpm gpm
Opticap
gpm
Durapore®
0.22 μm
TTOpticap
Opticap 0 XL
= 38 0mm Capsule
XL(1½
Capsule Legends
1010Legends
5 5 in.) Sanitary Refers
Refers
15Flange
15 20Inlet
20 to
to Connection
TT = 38 Type
Connection Type
mm
0 5 Opticap
(1½ Opticap XLT
XLT
in.) Sanitary
10 Capsule
InletLegends
Capsule
Flange
15 20 Legends Refers
Refers toXL
to Capsule Legends
Connection
Connection Type
Type Refers to Connection Type Opticap XLT Capsule Legends R
4.5 3.5 50
TT
TT==and
38 3.0 Outlet
38 mm mm(1(111//22 in.)
in.)Sanitary
Sanitary Flange
FlangeInlet
Inlet60and
andOutlet
Outlet and Outlet TT TT== 3838 mm
mm(1(111//22 in.)
in.)Sanitary
Sanitary Flange TT =and
FlangeInlet
Inlet 38 Outlet
and mm (11/ 2 in.) Sanitary Flange Inlet and Outlet
Outlet TT = 38 mm (11/ 2 in.) Sanitary Flange In
4.0 TTTT 40 TT 45
FFFF
FF ==19
=  19 2.5mm
mm ((¾
33//4 in.)
( 4 in.)
in.)
HH Sanitary
Sanitary
Sanitary Flange
Flange
Flange Inlet
Inlet
Inlet and
and Outlet
Outlet HH = 16 HH = 16 mm
3.0 mm (5/8 in.) Hose Barb
HH
HH = 16 mm ( in.)
55//Inlet
( 88 in.)Hose
Hose Barb
Barb Inlet
Inlet FF
and
and = 19
Outlet
Outlet mm (3/ 4 in.) Sanitary Flange Inlet and Outlet HH = 16 mm (5/ 8 in.) Hose Barb Inlet an
3.5
and Outlet
HH
5035 and Outlet
40 Contact Information
Pressure Drop (bar)

THTH TH
Pressure Drop (bar)

HH
HH== 14 14 mm mm(( /16
99/ 16 in.)
in.) Hose Barb Inlet and Outlet
BB Hose Barb Inlet and Outlet
TH
BB =
TH = 38
38 mm
mm(1(1 /22 in.)
1 1/ in.)Sanitary
Sanitary Flange HH =and
FlangeInlet
Inlet 14 16
and mm ( 16(( in.)
16 mm
mm9 / 55/ Hose
/88 in.)
in.) Barb Inlet and Outlet
Hose
Hose TH = 38 mm (11/ 2 in.) Sanitary Flange In
Pressure Drop (bar)

BB 2.5
3.02.0 30 35
HH = 
TH = 14
38 mm
mm (⁹⁄₁₆
(1 in.)Sanitary
11//2 in.) Hose Barb InletInlet40and
Flange 14 mmTH
(99/= 38
in.) mm (1½ in.) Sanitary
Barb Flange Inlet
Outlet TH = 38 mm (1 1/ 2 in.) Sanitary Flange Inlet and 14 mm (9/ 16 in.) Barb Outlet
TH = 2.5
38 mm (1 2 in.) Sanitary Flange Inlet 25and 14 mm ( 16 in.) 16
/ 2.0 Barb Outlet 30
and Outlet and 16 mm (5/8 in.) Hose Barb Outlet
Hose
Hose
2.0
1.5 Barb
Barb Outlet
Outlet 30 BB
BB =
= 25
25 mm
mm (1
(1 in.)
in.) Hose
Hose Barb
Barb
25 Inlet
Inlet and
and Hose
Outlet
Outlet Barb Outlet BB = 25 mm (1 in.) Hose Barb Inlet and
TH = 38 mm (1½ in.) Sanitary Flange Inlet20 BB = 25 1.5 mm (1 in.) Hose Barb Inlet and Outlet
20
and
1.51.0 14 mm (9/16 in.) Hose Barb Outlet
20 15
1.0 15
1.0 10 10
0.5 10 0.5
0.5 5 5
psid

65
psid
psid

0.0
0.0 00 0.0 0
00 2020 4040 6060 8080 0 20 40 60 80
Flow
FlowRate
Rate(L/min)
(L/min) Flow Rate (L/min)
77
Filters
TYPICALContaining
TYPICALCLEAN Multilayer
CLEANWATER
WATER FLOW Durapore
FLOWRATES:
®
0.45/0.22
RATES:STERILE
STERILEAND μm Membrane
ANDGAMMA
GAMMACOMPATIBLE
COMPATIBLE Durapore® Family Guide
TYPICAL
TYPICALCLEAN
CLEANWATER
WATERFLOW
FLOWRATES:
RATES:STERILE
STERILEAND
ANDGAMMA
GAMMACOMPATIBLE
COMPATIBLE
Typical Clean Water Flow Rates – Sterile and Gamma-Compatible Capsules Overview
Selection & Applications Guide
0.45/0.22
Opticap ® µm
0.45/0.22
XL µmMembrane
10 Membrane
Capsules — Multilayer 0.45/0.22 ®µm
0.45/0.22
Opticap µm
XLT Membrane
Membrane
10 Capsules — Multilayer Formats
Durapore gpm®
0.45/0.22
0.45/0.220.45/0.22
µm
gpm µm μm Membrane
Membrane
Membrane Durapore
0.45/0.22
0.45/0.22®
µm
gpmgpm 0.45/0.22
µmMembrane μm Membrane
Membrane
0 0
3.0 3.0
gpm gpm
5 5 10 10 15 15 20 20 0 0
4 gpm
5 5 10 10 15 15 20 20 OptiScale® Capsules
4 gpm
0 0
3.0 3.0
2.5
5 T
5T
TT
10 10 15 15 20 2040 40 0 0
3.5 3.5
4 4
5 T
5T
TT
10 10 15 15 20 20
50 50 Cartridge Filters
2.5 FF FF 35 35 BB BB
40 40 3 3
Cartridges
(bar) (bar)

(bar) (bar)
HH
T THH
TT HH
T THH
TT
(bar)(bar)

(bar)(bar)
3.5 3.5 50 50
2.5 2.5
2.0 TH
FFTH
FF 30 30 TH
BBTH
BB 40 40
2.0 35 35 2.532.53
FH
HHFH
HH HHHH
Drop Drop

Drop Drop
Optiseal® Cartridges
DropDrop

DropDrop
25 25
2.0 2.0 TH TH 30 30 TH TH 40 40
30
1.5 1.5 2 2.5
2.5 2 30
FH FH 20 20
Pressure

Pressure
Millidisk® Cartridges
Pressure

Pressure
25 25
1.521.52 30 30
1.5 1.5
1.0 15 15 20 20
1.0 20 20
Pressure
Pressure

Pressure
Pressure
10 10 1 1.5
1.5 1
1.0 1.0 15 15 20 20
10
0.5 0.5 10
5 5
10 10
0.5 0.5
1 1 Capsule Filters
psid psid

psid psid
psid psid

psid psid
0.5 0.5
0.0 0.0 0 0 0 0.5
0.5 0 010 010
0 0 20 20 40 40 60 60 8 0 850 5 0 0 20 20 40 40 60 60 80 80 Opticap® XL and XLT Capsules
0.0 0.0 0 0 0 0 0 0
0 0 2 0 Flow Rate
2 0 Flow 0 (L/min)
4Rate
4 0 (L/min)
60 60 80 80 0 0 2 0 Flow Rate
2 0 Flow 0 (L/min)
4Rate
4 0 (L/min)
60 60 80 80

Flow
Flow
Rate
Rate
(L/min)
(L/min) Flow
Flow
Rate
Rate
(L/min)
(L/min) Filters for Final Filtration
Millipak® Final Fill Capsules
Opticap
Opticap®
XLT
OpticapXLT 2020
20
XLT Capsules
Capsule
Capsule — Multilayer
Filters - -
Filters Opticap
Opticap
Opticap XLT
XLT
®
30
3030
XLT Capsules
Capsule Filters
Capsule —- Multilayer
Filters -
Durapore
0.45/0.22®
0.45/0.22
µm Membrane μm Membrane Durapore
0.45/0.22 µm
®
0.45/0.22
Membrane μm Membrane M
 illidisk® Barrier Cartridges
0.45/0.22
Opticap
OpticapXLT µm
XLT20Membrane
20
Capsule
Capsule
Filters
Filters
- - 0.45/0.22
Opticap
Opticap XLTµm
XLT30Membrane
30
Capsule
Capsule
Filters
Filters
- - and Millipak® Barrier Capsules
0.45/0.22
0.45/0.22µm
gpmgpm µmMembrane
Membrane 0.45/0.22
0.45/0.22µm
gpmgpm µmMembrane
Membrane
0 0 5 10 10 15 15 20 20 0 0 5 5 10 10 15 15 20 20
5
3.0 3.0
gpm gpm 3.0 3.0
gpm gpm
20 2040 40
0 0
3.0 3.0
2.5
5 T
5T
TT
10 10 15 15 20 2040 40
3.0
0 0
3.0
2.5 2.5
5 T
5T
TT
BB BB
10 10 15 15
Durapore® 0.1 μm & 0.22 μm
2.5 BB BB 35 35 35 35
40 40 40 40
(bar) (bar)

HH
Durapore® 0.45 μm
(bar) (bar)

HH T THH
TT
(bar)(bar)

T THH
TT
(bar)(bar)

2.5 2.5 TH
BBTH
BB 30 30 2.5 2.5
2.0 TH
BBTH
BB 30 30
2.0 2.0 35 35 2.0 35 35
HHHH
Drop Drop

HHHH
Drop Drop

Durapore® 5.0 μm
DropDrop

25 25
DropDrop

25 25 TH TH 30 30
2.0 2.0 TH TH 30 30 2.0 2.0
1.5
1.5 1.5 1.5
20 20 20 20
Pressure
Pressure

Pressure

25 25
Multimedia Durapore®
Pressure

25 25
1.5 1.5 15 15 1.5 1.5
1.0 15 15
1.0 1.0 1.0 20 20
20 20
Pressure
Pressure
Pressure
Pressure

1.0 1.0
0.5
10 10
15 15 1.0 1.0
0.5
10 10
15 15 Charged Durapore® 0.22 μm
0.5 0.5
5 5 5 5
10 10 10 10
Multilayer Durapore®
psid
psid psid

0.5 0.5 psid psid

psid psid

0.5 0.5
0.0 0 0 0.0 0.0 0 0
0.0
0 0 20 20 40 40 60 60 8 0 850 5 0 0 20 20 40 40 60 60 8 0 850 5
Durapore® CBR 0.1 μm &
psid

0.0 0.0 0 0 0.0 0.0 0 0

2 0 Flow Rate 0 (L/min) 2 0 Flow Rate 0 (L/min)
0 0 2 0 Flow 4Rate
4 0 (L/min)
60 60 80 80 0 0 2 0 Flow 4Rate
4 0 (L/min)
60 60 80 80
0.2 μm
Flow
Flow
Rate
Rate
(L/min)
(L/min) Flow
Flow
Rate
Rate
(L/min)
(L/min)
Hydrophobic Durapore®
0.22 μm
Opticap® XL Capsule Legends Refer Opticap® XLT Capsule Legends Refer
to Connection Type to Connection Type Hydrophobic-hydrophilic
Durapore® 0.22 μm
TT = 38 mm (1½ in.) Sanitary Flange Inlet TT = 38 mm (1½ in.) Sanitary Flange Inlet
and Outlet and Outlet
FF = 19 mm (¾ in.) Sanitary Flange Inlet HH = 16 mm (5/8 in.) Hose Barb Inlet
and Outlet and Outlet Contact Information
HH = 14 mm (⁹⁄₁₆ in.) Hose Barb Inlet TH = 38 mm (1½ in.) Sanitary Flange Inlet
and Outlet and 16 mm (5/8 in.) Hose Barb Outlet
TH = 38 mm (1½ in.) Sanitary Flange Inlet BB = 25 mm (1 in.) Hose Barb Inlet and Outlet
and 14 mm (9/16 in.) Hose Barb Outlet

66
Filters Containing Multilayer Durapore® 0.45/0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
OptiScale Capsule Filters
® Formats
OptiScale® Capsules
Cartridge Filters
S H G L A
Cartridges
Optiseal® Cartridges
OptiScale® Capsule Size Quantity per pkg.
Capsule Filter Millidisk® Cartridges
25 = 25 mm 3 = 3/pk
47 = 47 mm 6 = 6/pk
Capsule Filters
Membrane Type/Pore Size Sterilization Connection Type Opticap® XL and XLT Capsules
HGL = H
 ydrophilic Multilayer A = Autoclavable HH = 6 mm (1/4 in.) Hose Barb Inlet and Outlet
Durapore® 0.45 µm/0.22 µm FF = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet
Filters for Final Filtration
FH = 19 mm (3/4 in.) Sanitary Flange Inlet and
6 mm (1/4 in.) Hose Barb Outlet Millipak® Final Fill Capsules
NB = Female Luer-Lok™ Inlet and Male Luer-Lok™ Outlet
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Cartridge Filters
Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
C H G L T P 3
Durapore® 5.0 μm
Multimedia Durapore®
Cartridge Filter Cartridge Length
Charged Durapore® 0.22 μm
1 = 10-inch
2 = 20-inch Multilayer Durapore®
3 = 30-inch Durapore® CBR 0.1 μm &
0.2 μm
Membrane Type/Pore Size Cartridge Code Quantity per pkg.
Hydrophobic Durapore®
HGL = H
 ydrophilic Multilayer 0 = (2-222) O-ring TP3 = 3/pk 0.22 μm
Durapore® 0.45 µm/0.22 µm 7 = (2-226) O-ring locking
adapter and spear Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

67
Filters Containing Multilayer Durapore® 0.45/0.22 μm Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Opticap® XL Capsule Filters Formats
OptiScale® Capsules
Cartridge Filters
K H G L 1 0 1
Cartridges
Optiseal® Cartridges
Opticap® XL Capsule Size Quantity per pkg.
Capsule Filter
10 = Opticap® XL 10 1 = 1/pk Millidisk® Cartridges

Capsule Filters
Membrane Type/Pore Size Sterilization Connection Type
Opticap® XL and XLT Capsules
HGL = H
 ydrophilic Multilayer A = Autoclavable TT = 38 mm (1 1/2 in.) Sanitary Flange Inlet and Outlet
Durapore® 0.45 µm/0.22 µm G = Gamma-Compatible FF = 19 mm (3/4 in.) Sanitary Flange Inlet and Outlet
S = Sterile HH = 14 mm ( 9/16 in.) Hose Barb Inlet and Outlet Filters for Final Filtration
TH = 38 mm (11/2 in.) Sanitary Flange Inlet and Millipak® Final Fill Capsules
14 mm ( 9/16 in.) Hose Barb Outlet
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Opticap® XLT Capsule Filters
Durapore® 0.1 μm & 0.22 μm
K H G L T 1 Durapore® 0.45 μm
Durapore® 5.0 μm
Opticap® XLT Sterilization Gauge Port Quantity per pkg. Multimedia Durapore®
Capsule Filter Charged Durapore® 0.22 μm
A = Autoclavable T=W
 ithout 1 = 1/pk
G = Gamma-Compatible Gauge Port
Multilayer Durapore®
S = Sterile
Membrane Type/Pore Size Capsule Size Connection Type Durapore® CBR 0.1 μm &
HGL = H
 ydrophilic Multilayer 1 = Opticap XLT 10
®
TT = 38 mm (11/2 in.) Sanitary Flange Inlet and Outlet
0.2 μm
Durapore® 0.45 µm/0.22 µm 2 = Opticap® XLT 20 HH = 16 mm (5/8 in.) Hose Barb Inlet and Outlet Hydrophobic Durapore®
3 = Opticap® XLT 30 TH = 38 mm (1 1/2 in.) Sanitary Flange Inlet and 0.22 μm
16 mm (5/8 in.) Hose Barb Outlet
Hydrophobic-hydrophilic
BB = 25 mm (1 in.) Hose Barb Inlet and Outlet
Accessory Durapore® 0.22 μm
Description Qty/Pk Cat. No.
Standard Opticap® XLT Capsule Filter Stand 1/pk XLTSTAND1 Contact Information

68
Filters Containing Durapore CBR 0.1 μm and ® Durapore® Family Guide

0.2 μm Membrane Overview

Selection & Applications Guide
For bioburden reduction in non-critical applications Formats
OptiScale® Capsules
Filters containing Durapore® CBR 0.1 μm
Cartridge Filters
and 0.2 μm hydrophilic polyvinylidene
Cartridges
fluoride (PVDF) membrane are designed for
particle removal and bioburden control in Optiseal® Cartridges
non-critical applications, which do not require Millidisk® Cartridges
sterilizing-grade filter performance.
Capsule Filters
Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Benefits Filter Formats

Durapore® 0.1 μm & 0.22 μm
• Protects processes from microbial contamination • Cartridge filters
Durapore® 0.45 μm
• Low protein binding membrane yields high protein
Durapore® 5.0 μm
recovery with minimal product loss
Multimedia Durapore®
• Broad chemical compatibility, low extractables
Charged Durapore® 0.22 μm
• For filtration processes requiring high flow rates
Multilayer Durapore®
and throughput
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

69
Filters Containing Durapore® CBR 0.1 μm and 0.2 μm Membrane Durapore® Family Guide

Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Durapore® CBR 0.1 μm (per 10-inch element) Durapore® CBR 0.2 μm (per 10-inch element)
Formats
Nominal Dimensions
Outside diameter: 6.9 cm (2.7 in.) 6.9 cm (2.7 in.) OptiScale® Capsules
Filtration Area 0.69 m (7.4 ft )
2 2
0.69 m (7.4 ft )
2 2
Cartridge Filters
Materials of Construction Cartridges
Filter membrane: Hydrophilic PVDF Hydrophilic PVDF
Film edge: Polypropylene Polypropylene Optiseal® Cartridges
Supports: Polypropylene Polypropylene
Structural components*: Polypropylene Polypropylene
Millidisk® Cartridges
Vent O-rings: Fluorocarbon rubber or silicone Fluorocarbon rubber or silicone
Maximum Differential Pressure Capsule Filters
Forward: 5.5 bar (80 psid) at 25 °C, 1.75 bar (25 psid) at 80 °C, 345 mbar (5 psid) at 135 °C
Opticap® XL and XLT Capsules
Reverse: 3.4 bar (50 psid) at 25 °C, intermittent
Bubble Point at 23 °C ≥ 4830 mbar (70.0 psig) air with water ≥ 3100 mbar (45.0 psig) air with water
Filters for Final Filtration
Air Diffusion Through a water wet membrane at ambient temperature:
≤ 20 cc/min at 3860 mbar (56 psi) ≤ 13.3 cc/min at 2.8 bar (40 psig) Millipak® Final Fill Capsules
per 10-inch cartridge per 10-inch cartridge
M
 illidisk® Barrier Cartridges
Bacterial Retention Samples of the Durapore® membrane used in these cartridges meet the criteria for quantitative retention and Millipak® Barrier Capsules
of 107 CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM© F838 methodology.
Total Organic Carbon (TOC) / Autoclaved filter effluent meets the WFI requirement of USP <643>, for Total Organic Carbon and USP <645>
Conductivity for Water Conductivity at 25 °C after a WFI flush of: Durapore® 0.1 μm & 0.22 μm
3.5 L 5.5 L
Durapore® 0.45 μm
Animal Origin Statement Based on the current information from our suppliers, all component materials used in the manufacture of this
device are either animal-free or in compliance with EMA/410/01. Durapore® 5.0 μm
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6). Multimedia Durapore®
Toxicity Component materials meet the criteria for the USP <88> Biological Reactivity Tests for Class VI Plastics. Charged Durapore® 0.22 μm
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers. Multilayer Durapore®
*Outer sleeve, core and end caps Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

70
 Filters Containing Durapore® CBR 0.1 μm and 0.2 μm Membrane Durapore® Family Guide

Typical Clean Water Flow Rates Overview

Selection & Applications Guide
Cartridge Filters – 0.1 μm Durapore® Cartridge Filters – 0.2 μm Durapore® Formats
0.1Membrane (CVVI)
µm Hydrophilic Durapore (CVVI) Membrane (CVDI)
0.2 µm Hydrophilic Durapore (CVDI)
OptiScale® Capsules
gpm gpm
0 5 10 15 20 0 5 10 15 20 Cartridge Filters
2.5 1.5
35
10-inch Cartridge
20-inch Cartridge
10-inch Cartridge
20-inch Cartridge
20
Cartridges
30
2.0 30-inch Cartridge 30-inch Cartridge
Optiseal® Cartridges
Pressure Drop (bar)

Pressure Drop (bar)

25 15
1.0
1.5
20 Millidisk® Cartridges
10
1.0 15
0.5
10
5
Capsule Filters
0.5
5 Opticap® XL and XLT Capsules

psid
psid

0.0 0 0.0 0
0 10 20 30 40 50 60 70 80 0 10 20 30 40 50 60 70 80

Flow Rate (L/min) Flow Rate (L/min) Filters for Final Filtration
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Ordering Information Durapore® 0.45 μm

Durapore® 5.0 μm
Cartridge Filters Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
C V D I T P
Durapore® CBR 0.1 μm &
0.2 μm
Cartridge Pore Size Cartridge Length O-ring Material Hydrophobic Durapore®
Filter 0.22 μm
VI = 0.1 μm 1 = 10-inch E = Fluorocarbon rubber
DI = 0.2 μm 2 = 20-inch S = Silicone
Hydrophobic-hydrophilic
3 = 30-inch
Membrane Type Cartridge Code Packaging Durapore® 0.22 μm
4 = 40-inch Code
V = Durapore® 0 = (2-222) O-ring (Code 7 only*)
5 = (2-222) O-ring with spear TP = 1/pk
assembly* Contact Information
7 = (2-226) O-ring with locking
outlet and spear assembly *Durapore® CBR 0.1 only

71
Filters Containing Hydrophobic 0.22 μm Durapore® Family Guide

Durapore Membrane ®
Overview
Selection & Applications Guide
For sterile filtration of non-aqueous solutions and gases Formats
OptiScale® Capsules
Filters containing hydrophobic Durapore®
Cartridge Filters
0.22 μm membrane are used for sterile
Cartridges
filtration of liquids such as alcohols,
solvents, oils, emulsions and for sterile Optiseal® Cartridges
tank and gas venting. Millidisk® Cartridges

Capsule Filters
Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Benefits Filter Formats

Durapore® 0.1 μm & 0.22 μm
• Hydrophobic sterilizing-grade membrane that • Cartridge filters
eliminates particles and microorganisms even at Durapore® 0.45 μm
• Optiseal® cartridges
high pH Durapore® 5.0 μm
• Millidisk® cartridges Multimedia Durapore®
• Low protein binding membrane yields high protein
recovery with minimal product loss • Opticap® XL capsules Charged Durapore® 0.22 μm
• Broad chemical compatibility, low extractables • Millipak® Final Fill capsules Multilayer Durapore®
• For processes requiring high flow rates Durapore® CBR 0.1 μm &
and throughputs 0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

72
Filters Containing Hydrophobic 0.22 μm Durapore® Membrane Durapore® Family Guide

Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Optiseal® Cartridge 5-inch Cartridge Per 10-inch Cartridge
Formats
Nominal Dimensions
Maximum length: 12.0 cm (4.7 in.) 12.5 cm (5 in.) 25 cm (10 in.) OptiScale® Capsules
Outside diameter: 6.9 cm (2.7 in.) 6.9 cm (2.7 in.) 6.9 cm (2.7 in.)
Cartridge Filters
Filtration Area 0.18 m2 (1.9 ft2) — 0.7 m2 (7.4 ft2)
Cartridges
Materials of Construction
Filter membrane: Hydrophilic PVDF Hydrophilic PVDF Optiseal® Cartridges
Supports: Polypropylene Polypropylene
O-rings: Silicone Silicone
Millidisk® Cartridges
Connections Double 2-123 O-ring Code 7 (2-226) O-ring with locking tab and spear
Code 5 (2-222) O-ring with spear Capsule Filters
Code 0 (2-222) O-ring
Opticap® XL and XLT Capsules
Maximum Differential Pressure
Forward: 5.5 bar (80 psid) at 25 °C; 3.5 bar (50 psid) at 80 °C; 0.35 bar (5 psid) at 135 °C
Reverse: 3.4 bar (50 psid) at 25 °C Filters for Final Filtration
Bubble Point at 23 °C ≥ 2000 mbar (29 psig) in water ≥ 2000 mbar (29 psig) in water Millipak® Final Fill Capsules
0.22 µm hydrophobic ≥ 1240 mbar (18 psig) in 60/40 IPA/water ≥ 1240 mbar (18 psig) in 60/40 IPA/water
Durapore® membrane ≥ 1170 mbar (17 psig) in 70/30 IPA/water ≥ 1170 mbar (17 psig) in 70/30 IPA/water M
 illidisk® Barrier Cartridges
≥ 1170 mbar (17 psig) in 100 IPA and Millipak® Barrier Capsules
Nitrogen Diffusion At 1.0 bar (15 psig) in 60/40 IPA/water at 23 °C: At 1.7 bar (25 psig) in water at 23 °C:
≤ 2 cc/min ≤ 5.0 mL/min ≤ 10.0 mL/min
At 1.7 bar (25 psig) in water at 23 °C: Durapore® 0.1 μm & 0.22 μm
≤ 5.0 cc/min Durapore® 0.45 μm
Bacterial Endotoxin < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This meets the requirements of USP
Durapore® 5.0 μm
<85>.
Bacterial Retention Quantitative retention of 107 CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM© F838 methodology. Multimedia Durapore®
Sterilization 30 steam-in-place cycles of 30 min at 135 °C; 30 steam-in-place cycles at 30 min at 126 °C; Charged Durapore® 0.22 μm
10 autoclave cycles of 30 min at 126 °C. 30 autoclave cycles of 60 min at 126 °C.
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

73
Filters Containing Hydrophobic 0.22 μm Durapore® Membrane Durapore® Family Guide

Millidisk® Cartridge Filter Specifications Overview

Selection & Applications Guide
Description Millidisk® 10 Millidisk® 20 Millidisk® 30 Millidisk® 40
Formats
Filtration Area 500 cm2 (0.54 ft2) 1000 cm2 (1.08 ft2) 1500 cm2 (1.61 ft2) 2000 cm2 (2.15 ft2)
Materials of Construction OptiScale® Capsules
Filter membrane: Hydrophobic Durapore® PVDF membrane Cartridge Filters
Structural components: Polysulfone
O-rings: Silicone Cartridges
Maximum Differential Pressure Optiseal® Cartridges
Forward: 4.1 bar (60 psid) at 25 °C
1.7 bar (25 psid) at 80 °C Millidisk® Cartridges
345 mbar (5 psid) at 123 °C
Reverse: 690 mbar (10 psid) at 25 °C
Capsule Filters
Bubble Point at 23 °C ≥ 1170 mbar (17.0 psig) in 100% IPA using nitrogen as the test gas
Opticap® XL and XLT Capsules
Connections Millidisk® filters incorporate a double 2-118 (silicone) O-ring seal and are used with Millidisk® or Millidisk®/
Milligard® stainless steel housings.
Gravimetric Extractables Maximum values post autoclaving and a 24 hour soak in ASTM® Type 1 reagent grade water for hydrophilic Filters for Final Filtration
units and in 70/30 IPA/Water solution for hydrophobic units: Millipak® Final Fill Capsules
2.5 mg/unit 5 mg/unit 7.5 mg/unit 10 mg/unit
M
 illidisk® Barrier Cartridges
Oxidizable Substances Meets the USP Oxidizable Substances Test requirements for sterile purified water after steaming and a water
flush of 200 mL. and Millipak® Barrier Capsules
Bacterial Endotoxin An aqueous extraction from a Millidisk® filter contains < 0.5 EU/mL bacterial endotoxin as determined by the
LAL test. This meets the requirements of USP <85>.
Durapore® 0.1 μm & 0.22 μm
Bacterial Retention Quantitative retention of 107 CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM© F838 methodology.
Durapore® 0.45 μm
Sterilization
Autoclave: 126 °C, 60 minutes, up to 5 times Durapore® 5.0 μm
Steam-in-place: 135 °C, 60 minutes, up to 5 times
Multimedia Durapore®
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Charged Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

74
Filters Containing Hydrophobic 0.22 μm Durapore® Membrane Durapore® Family Guide

Opticap® XL Autoclavable Capsule Filter Specifications Overview

Selection & Applications Guide
Description Opticap® XL 4 Opticap® XL 5 Opticap® XL 10
Formats
Nominal Dimensions
Maximum length: 14.2 cm (5.6 in.) 21.6 cm (8.5 in.) 33.5 cm (13.2 in.) OptiScale® Capsules
Body diameter: 8.4 cm (3.3 in.) 10.7 cm (4.2 in.) 10.7 cm (4.2 in.)
Vent to vent diameter: 12.5 cm (4.9 in) 14.5 cm (5.7 in.) 14.5 cm (5.7 in.) Cartridge Filters
Filtration Area 0.19 m² (2.09 ft²) 0.35 m2 (3.7 ft2) 0.69 m2 (7.4 ft2) Cartridges
Materials of Construction Optiseal® Cartridges
Filter membrane: Hydrophobic PVDF Hydrophobic PVDF Hydrophobic PVDF
Film edge: Polypropylene Polypropylene Polypropylene
Millidisk® Cartridges
Supports: Polypropylene Polypropylene Polypropylene
Structural components*: Polypropylene Polypropylene Polypropylene Capsule Filters
Vent O-rings: Silicone Silicone Silicone
Opticap® XL and XLT Capsules
Vent/Drain 1/4 in. hose barb with double O-ring seal: connects to 1/8 in. tubing
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C 5.5 bar (80 psi) at 23 °C
Filters for Final Filtration
2.8 bar (40 psi) at 60 °C 2.8 bar (40 psi) at 60 °C
1.0 bar (15 psi) at 80 °C 1.0 bar (15 psi) at 80 °C Millipak® Final Fill Capsules
Maximum Differential Pressure M
 illidisk® Barrier Cartridges
Forward: 5.5 bar (80 psid) at ambient temperature, 1.0 bar (15 psid) at 80 °C and Millipak® Barrier Capsules
Reverse: 3.4 bar (50 psid) at ambient temperature
Bubble Point at 23 °C ≥ 1170 mbar (17.0 psig) nitrogen ≥ 1170 mbar (17.0 psig) nitrogen > 1240 mbar (18.0 psig) nitrogen
with 70/30 IPA/water with 70/30 IPA/water with 60/40 IPA/water Durapore® 0.1 μm & 0.22 μm
Nitrogen Diffusion Through a water wet membrane at ambient room temperature at 1720 mbar (25 psig) nitrogen: Durapore® 0.45 μm
≤ 5 cc/min ≤ 5 cc/min ≤ 10 cc/min
Durapore® 5.0 μm
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test. This meets
the requirements of USP <85>. Multimedia Durapore®
Bacterial Retention Quantitative retention of 107 CFU/cm2 Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology. Charged Durapore® 0.22 μm
Sterilization May be autoclaved for 20 cycles of 30 minutes at 126 °C. Multilayer Durapore®
Non-Fiber Releasing Meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Durapore® CBR 0.1 μm &
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics. 0.2 μm
European Pressure Equipment This product complies with the European Pressure Equipment Directive, 2014/68/EU of 15 May 2014. This product Hydrophobic Durapore®
Directive has been classified under article 4 § 3 of the Pressure Vessel Directive. It has been designed and manufactured in
accordance with sound engineering practice to ensure safe use. In compliance with Article 4 § 3 of the Directive, 0.22 μm
2014/68/EU, this product does not bear the CE mark.
Hydrophobic-hydrophilic
*Cage, core, end caps, and capsule housing Durapore® 0.22 μm

Contact Information

75
Filters Containing Hydrophobic 0.22 μm Durapore® Membrane Durapore® Family Guide

Millipak® Final Fill Capsule Filter Specifications Overview

Selection & Applications Guide
Description Millipak® Final Fill 20 Millipak® Final Fill 60 Millipak® Final Fill 200
Formats
Nominal Dimensions
Maximum length 8.1 cm (3.2 in.) 10.9 cm (4.3 in.) 14.5 cm (5.7 in.) OptiScale® Capsules
Body diameter 7.6 cm (3.0 in.) 7.6 cm (3.0 in.) 7.6 cm (3.0 in.)
Body diameter w/ anti-roll edges – – 8.1 cm (3.2 in.) Cartridge Filters
Filtration Area 100 cm (0.11 ft )
2 2
300 cm (0.32 ft )
2 2
1000 cm (1.08 ft )
2 2 Cartridges
Aseptic Multi-Purpose Port 3.2 mm (1/8 in.) hose barb Optiseal® Cartridges
Materials of Construction Millidisk® Cartridges
Filter membrane: Hydrophobic Durapore® PVDF (polyvinylidene fluoride) membrane
Support discs Polysulfone
Filter capsule Polysulfone Capsule Filters
Aseptic Multi-Purpose Port (AMPP) Polyethersulfone
Opticap® XL and XLT Capsules
AMPP O-rings Silicone
Hold-up Volume 20 psi above the Bubble Point Specification for 1 minute
Filters for Final Filtration
1.1 mL 3.2 mL 7.2 mL
Millipak® Final Fill Capsules
Maximum Inlet Pressure 60 psi (4.1 bar) at 25 °C
Maximum Differential Pressure M
 illidisk® Barrier Cartridges
Forward: 60 psi (4.1 bar) at 25 °C and Millipak® Barrier Capsules
25 psi (1.7 bar) at 80 °C
Reverse: 10 psi (0.7 bar) at 25 °C
Bubble Point at 23 °C ≥ 29 psi (2000 mbar) air with water Durapore® 0.1 μm & 0.22 μm
≥ 18 psi (1240 mbar) in 60/40% IPA water Durapore® 0.45 μm
≥ 17 psi (1170 mbar) in 70/30% IPA water
Microbial challenge testing Vents were tested utilizing a bacterial challenge method with 107 Brevundimonas diminuta assuring a sterile
Durapore® 5.0 μm
fluid path during actuation. Multimedia Durapore®
Bacterial Endotoxin Aqueous extraction contains < 0.25 EU/mL per device as determined using the Limulus Amebocyte Lysate (LAL)
test, meeting requirements of USP <85>, EP 2.6.14 and JP 4.01.
Charged Durapore® 0.22 μm
Total Organic Carbon (TOC)/ Samples exhibited < 500 ppb TOC per USP <643> and < 1.3 μS/cm conductivity per USP <645> at 25 °C after Multilayer Durapore®
Conductivity sterilization and a water flush of: Durapore® CBR 0.1 μm &
1.0 L 2.0 L 5.0 L 0.2 μm
Sterilization Device integrity and retention was maintained after 3 autoclave cycles of 90 minutes at 126 °C. Devices can Hydrophobic Durapore®
withstand a dose ≤ 40 kGy gamma exposure.
0.22 μm
Toxicity Component materials meet the criteria of the USP <88> Biological Reactivity Test for Class VI Plastics.
Hydrophobic-hydrophilic
Particle Shedding Effluent meets the acceptance criteria set forth in USP <788> for large volume parenterals.
Durapore® 0.22 μm
Non-Fiber Releasing This product was manufactured with a Durapore® membrane which meets the criteria for a “non-fiber releasing”
filter as defined in 21 CFR 210.3 (b)(6), validated based on large volume parenteral specifications as detailed in
USP <788> Particulate Matter in Injections. Contact Information
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182 based on
information provided by raw material suppliers.
Quality Management System These products are manufactured in a facility which is certified to ISO® 9001:2015 Quality Management Systems.

76
 0 PSIG 25
Outlet 0 PSIG Outlet 0 PSIG Outlet 0.40 0 PSIG Outlet 0 PSIG Outlet 0.40 0 PSIG Outlet

Different
6 30 1.5 156PSIG Inlet 30

Differen
2.0 1.5 15 PSIG Inlet
0.41.5 15 PSIG20Inlet 15 PSIG
20 Inlet 0.4 15 PSIG Inlet 0.35 2.0 15 PSIG Inlet
5 0.35 5
30 PSIG Inlet 30 PSIG Inlet 30 PSIG Inlet 30 PSIG Inlet 30 PSIG Inlet 30 PSIG Inlet

Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

MCVL 10S 03 15 5 MCGL 10S 03 1.0 15 25 MCGB 10S 02 1.0 5 25
1.0 0.30 0.30
MCVL 20S 03 0.3 MCGL 20S 03 1.5 MCGB 20S 02 4 4
10 10 0.3 1.5
MCVL 30S 03 4 MCGL 30S 03 20 MCGB 30S 01 0.25
0.5 4 20 0.25
0.5 0.5 5
MCVL 40S 03 5 MCGL 40S 03 MCGB 40S 01
0.20 3 0.20 3
3 3

bar
15 15

Filters Containing Hydrophobic 0.22 μm Durapore® Membrane

0
Durapore® Family Guide

bar
1.0 0.0 0.0 1.0

bar
0.20.0 0 0.2
4 5 6 0 2 4 6 8 10 12 14 0 1 2 3 4 5 6 7 8 9 100.15 2
0.15
2
2 10 2 10
(L/min) 0.1 Flow Rate (L/min) 0.5 Flow
0.1 Rate (L/min) 0.10 0.5 0.10
1 5 1 1 5 1
0.05 0.05

psid

psid

psid

psid

psid

psid
Typical Air Flow Rates and Pressure Drops
0.0
0 10 20 30 40 50 60 70 80 90
0 0.0
0 10 20 30 40 50 60
0.0 0
70 0 80 1090 20 30 40 50
0.00
60 70 0 20
80 40
90
0
60
0.0
80 100 120 1 400 1 60
10 180
20
0
30 40 50 60 70 80 90
0 0.00
0 20 40 60 80 100 Overview
120 1 40 1 60 180
0

Air Flow Rate (Nm3 / h) Air Flow Rate (Nm3 /h) Air Flow Rate (Nm3 / h) Air Flow Rate (Nm3 /h) Air Flow Rate (Nm3 /h) Air Flow Rate (Nm3 /h)
Selection & Applications Guide
Optiseal
philic Filters Optiseal Cartridge
Millidisk®
Cartridge with – Hydrophobic
5.00.22
μm Hydrophilic
µm Millidisk
Filters10-inch Cartridge
Millidisk®
with0.22Cartridge
®
μmµm
0.22 – Hydrophobic
Hydrophobic
Optiseal Filters
Cartridge with 0.22 µm
®
10-inch
10-inch Cartridge
Cartridge – Hydrophobic
with 0.22 µm Formats
Hydrophobic 0.22 μmMembrane
Durapore®Durapore Membrane Durapore
HydrophobicAirDurapore
®
@0.22
25 ºC μm Durapore
Flow RateHydrophobic
Membrane Membrane Membrane Durapore®Durapore
Hydrophobic 0.22 μmMembrane
Membrane
OptiScale® Capsules
scfm L/min scfm L/min scfm scfm
50 60 70
0.28
0 2 4 6
50
8 0 10 1012 14
20 1630 18 40
20 50
4.0
60 70
0.45
0 20
10
400 200
60 400 80 0600 100
0.28
2 800
4 1000
6 8 1200 140014
10 12
.7
16 18 20
4.0 0.45
0 20 40 60 80 100
Cartridge Filters
Differential Pressure (psid)

Differential Pressure (psid)

3.0 45 MCSL 10S 02 6 6
Cartridges
0 PSIG Outlet 3.5 0.40
3.0 0 PSIG Outlet 0 PSIG Outlet 3.5 0.40 0 PSIG Outlet
MCSL 20S 02 15 PSIG Inlet 15 PSIG Inlet
15 PSIG
40 Inlet MCSL 30S 01 0.35 8 15 PSIG Inlet 0.35
2.5 3.0 2.5 30 PSIG Inlet 5 3.0 30 PSIG Inlet 5
30 PSIG Inlet 30 PSIG Inlet
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

35 MCSL 40S 01
2.0
50 PSIG Inlet
30 2.5
0.30
2.0 6
50 PSIG Inlet
4 2.5
0.30
4 Optiseal® Cartridges
0.25 0.25
25 .35
Millidisk® Cartridges
0.14
1.5 2.0 0.14 2.0
1.5
0.20 3 MCGB 10 0.20 3
20 4
1.5 MCGB 20 1.5
MCHL 10S 03 1.0 15 0.15 0.15
1.0 2 2
MCHL 20S 03 1.0 MCGB 30 1.0
MCHL 30S 03 10 0.10 2 0.10
0.5
Capsule Filters
MCHL 40S 03 0.5 1 MCGB 40 1
5 0.5 0.05 0.5 0.05
bar

psid

psid

psid

psid
0.0

bar
bar
0 0.0
0.00 0 0 0.00
2 14 16 18 20 0.0 0.0 0.0 0 0.0 0

min)
0 70 140 2100 2802 350 6 490
4 420 8 105 6 012 14 16 18 20 0 20 40 0 16070180301 4 0
60 0 80 10010120 14020 21040 280 350
50 420 490 560 0 20 40 60 80 100 120 140 160 180
Opticap® XL and XLT Capsules
Air Flow Rate (L/min) Flow Rate (L/min) Air Flow Rate (Nm3Air Air Flow Rate (L/min)
/h)Flow Rate (SCFM) Air Flow Rate (Nm3 /h)

Typical Liquid
Typical AirTypical
Flow FlowRate
Air Typical
Flow
Rate andand Rate
Air
Pressure
Flow
and Rate
Pressure Pressure
Drop
Dropand Pressure
Drop Drop Liquid Flow Rate and Pressure Drop®
Typical Filters for Final Filtration
Opticap® XL 5 Capsules – Opticap® XL 5 Capsules – Opticap XL 5 Capsules –
Hydrophobic
Typical Air Durapore
Typical
Flow Rate
Air Typical
Flow
®
and 0.22
Rate
Air μm
Pressure
Flow
and Rate
Pressure
Drop and Hydrophobic
Pressure
Drop Drop Durapore® 0.22 μm Hydrophobic Durapore® 0.22 μm Millipak® Final Fill Capsules
Opticap XL Opticap
5 Capsule XL Opticap
with
5 Capsule
Hydrophobic
XL with
5 Capsule
Hydrophobic
Opticap
with Hydrophobic
XL Opticap
5 Capsule XL Opticap
with
5 Capsule
Hydrophobic
Opticap XL 5 Capsule with Hydrophobic Opticap XL 10 Capsule with Hydrophobic 10-inch Cartridge with 0.22 µm XL with
5 Capsule
Hydrophobic
Opticap
with Hydrophobic
XL Opticap
5 Capsule XL Opticap
with
5 Capsule
Hydrophobic
XL with
5 Capsule
Hydrophobic
with Hydrophobic
10 Capsule with Hydrophobic 10-inch Cartridge with 0.22 µm
Membrane,
Durapore0.220.22
FF
Durapore
Fitting*
µmMembrane
Membrane,
0.22
Durapore
µm Membrane,
FF 0.22
Fitting*
µm Membrane,
FFDurapore
Fitting*0.22FF
Membrane,
0.22
Durapore
Fitting*
µmMembrane
Membrane,
0.22
HH Fitting*
Durapore
µm Membrane,
HH 0.22Fitting* Membrane,
HH Durapore
Fitting* HH 0.22
Durapore
Fitting*
µm Membrane,
Membrane,
0.22
Durapore
µm Membrane,
TT0.22
TT Membrane,
Fitting*
Fitting*
µm Membrane
TT Fitting* TT Fitting* Hydrophobic Durapore Membrane
Durapore µm Durapore µm Durapore 0.22 µm Membrane
Hydrophobic Durapore Durapore
Membrane 0.22 µm M
 illidisk® Barrier Cartridges
Opticap
scfm XL Opticap
5 Capsule
scfm XLOpticap
with
5 Capsule
Hydrophobic
scfm XL with
5 Capsule
Hydrophobic
Opticap
with Hydrophobic
scfm
XL Opticap
5 Capsule
scfm
XLOpticap
with
5 Capsule
Hydrophobic
scfm
XL with
5 Capsule
Hydrophobic
Opticap
withgpm Hydrophobic
scfm
XL Opticap
5 Capsule
scfm
XLOpticap
with
5 Capsule
Hydrophobic
scfm
XL with
5 Capsule
Hydrophobic
with Hydrophobic
and Millipak® Barrier Capsules
gpm gpm gpm gpm gpm
Durapore
00 10.22
5 Durapore
0 µm
0 10 Membrane,
20 1 00.22
30 Durapore
µm
15 40200 20
0.7
Membrane,
FF
50
30 0.22
10 Fitting*
µm 50Membrane,
4020 FF
30Durapore
Fitting*
400
0
0.7
0.22
FF
5Durapore
5010 Fitting*
µm
20010 Membrane,
300.22
10
0.7
Durapore
µm
15 40
2000 20 Membrane,
HH
50
30 0.22
105 Fitting*
µm
4020 10 Membrane,
HH
30Durapore
50 Fitting*
15 40
00 HH
40.22
50
20 20Durapore
Fitting*
µm
8400 Membrane,
0.22
1260
20Durapore
µm
1680
40
00 20Membrane,
TT
1000.22
60
205 Fitting*
µm
40 10 Membrane,
80 TT
60 Fitting*
100 15 80 TT Fitting*
100
20 0 4 8 12 16 20
3.0 10 2.5
103.0 10 2.5 2.5
3.0 0.9 0.9
3.0 20 1.400.9 1.40 20
35 35 35
scfm scfm scfm 40 scfm scfm scfm 40 40 scfm scfm 12 12 12
40 scfm
0.6 T0
T PSIG
0.6 Outlet 0 PSIG
0.6 Outlet 0 PSIG Outlet T0
T PSIG Outlet 0 PSIG Outlet T0TPSIG Outlet 0.8 Outlet
0 PSIG 0.8 Outlet
0 PSIG 18
T0TPSIG Outlet 0.8 18
2.5 0 1 0FF 200
15 PSIG Inlet
301 0 40200
15 PSIG Inlet
10
5030
15
4020 5030
2.5
400 50
10 200 3010 40200
2.5 5030
10FF 4020
30 PSIG 5030 50
20 30 400 6020 80400
2.5 10060
20FF 8040 100
60 80 30 400
100
0.7 0.7 0.7 8 PSIG Inlet 2.0
8 2.5 158 PSIG
FF 2.0
2.5
Inlet 15 PSIG
2.0
2.5
Inlet 15 Inlet 15 PSIG
0.7
0.9
Inlet 15 PSIG
0.7
0.9
Inlet 1615
10
PSIG Inlet
10 0.7
10
0.9 16
HH 10 PSIG Inlet 10 3010 HH
Durapore 0.1 μm & 0.22 μm
Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

(bar)

30 PSIG
0.5 Inlet 30 PSIG
0.5 Inlet 30 HH PSIG Inlet 30 PSIG Inlet 30
35 PSIG Inlet HH ®

Drop (bar)

Drop (bar)

(bar)
Pressure Drop (bar)

Drop (bar)

3035PSIG Inlet 30 PSIG Inlet 30 PSIG Inlet 35

Pressure Drop (bar)

Drop (bar)
1.05 1.05

Pressure Drop (bar)

Pressure Drop (bar)

0.5
2.0
30
2.0 Outlet 3025 25 0.6
30
0.8Outlet 0.6
0.8 Outlet 1412 12 3012
25 0.6
0.8 14
0 PSIG
0.6Outlet 0 PSIG
0.6 Outlet 0 PSIG Outlet 2.0 0 PSIG Outlet 0 PSIG 0 PSIG Outlet 0 PSIG 2.0
0 PSIG
0.6
615 PSIG Inlet 1.5
6 2.0 1.5 1.5 30 30PSIG Inlet 80 PSIG Outlet 8 30 8
1568PSIG
Pressure Drop

15 PSIG
0.4 Inlet 15 PSIG
0.4 Inlet 2.0 Inlet 15 PSIG
2.0 Inlet 15 PSIG Inlet 1215 PSIG Inlet 12

Drop
0.4 8 8 15 15 PSIG Inlet
20 20 0.5
0.7 0.5
0.7 10 10 20 0.7
0.5
10
Durapore ®
0.45 μm
Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

30 PSIG
0.5 Inlet 30 PSIG
0.5 Inlet 30 PSIG Inlet 30 PSIG Inlet 30 1.5
PSIG Inlet 30 PSIG Inlet

Drop (bar)

Drop (bar)

Drop (bar)
0.5
1.5 30 PSIG Inlet 30 PSIG Inlet 30 PSIG Inlet
20 1.5 25 2025 0.4 1.5 106 6 0.70
25 0.6
6 0.70 10
20 20
PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

0.3 0.3 0.3 15 0.6 0.4

0.6 15 0.4
PressurePressure

PressurePressure

Pressure
Pressure
4 1.0
4 1.5 4 1.0 1.0 15
6 1.5 1.5 88 8 8 8
Durapore 5.0 μm
0.4 0.4 0.4 6 6 ®
1.0 1.0 1.0 20 0.3
20 0.5 20 0.3
0.5 0.3
0.5
1.0
0.2 0.2 0.2 10 10 10 64 4 4 6
0.3 0.3 0.3 102 1015 0.350.4
0.2 10 0.20.4 0.2
0.4 6 6 106 0.35

Pressure
2 0.5
1.0 2 0.5 0.5 15 15 4 4
4 1.0 1.0
Multimedia Durapore®
0.5
0.1 0.1 0.1 4 40.5 0.5 5 5 5 0.5 2 2 2
0.1
0.3 0.1
0.3 0.1
0.3
0.2 0.2 0.2 24 4 4 2
10 10 10
psid

psid

psid

psid

psid

psid

psid

psid

psid
psid

psid
psid

psid

psid

psid
0.0 0.0 0.0
0.0 00 0 0.0
0.0
2 0.570
0 0.0
0.5 0 40 1050 20 0.0
0.0
0.5 00 0 0.2
0.00 0.0 00 0.00.2 0.0
0.2
0.0 00 0 00 0.00 0
0.10
0 10
10 220
0 30
30 0 40 1050 2060 630
0.1 4 0 50
70 070
00.1 40801050 20260 3070 4080 50 90 60
8 090 0
0 80
10
10
20 2 30
90
20 30 40 50
60 3070 0 4080105090 20
60 0 70 1080 2 50
60 30
70 4080
30 4 0 5090
50 60 70
0.1
80
20 890
5 6 0 0 7010 40
0 5 60
20 30 0 804020
0.1
1005040
120 60
60
14000 70
0.1
8016020
10100
180
80 40
120
202 60 140
30 80160
40 100180
50 120
2 60140 70
160 80
180 2 0 10 20 30 40 Charged
5060 70 80 Durapore® 0.22 μm
Air Flow
FlowRate
Rate(Nm Air
3 / h)
Flow Rate (NmAir
3 / h)
Flow Rate (Nm3 / h) Air Flow Rate (NmAir
3 /h)
Flow Rate (Nm Air
3 /h)
Flow
FlowRate
Rate(Nm
3 /h)
Air Flow
FlowRate
Rate(Nm Air
3/h)
Flow Rate (Nm
Air
3/h)
Flow
FlowRate
Rate(Nm
Water (L/min) 3/h) Water Flow Rate (L/min)
psid

psid

psid

Water (L/min) Water (L/min)

psid

psid

psid

psid

psid

psid
Water Flow Rate (L/min) Water (L/min)
Multilayer Durapore®
0.0 0.0 0.0 0 0 0.0 0 0.0 0.0 0 0 0.0 0 0.0 0.0 0 0 0
0 10 20 30 040 10 70 0 40
50 2060 30 801050902060 3070 4080 50 90 60 70 0 80
10 20
90 30 040 10
50 20
60 30
70 0 40 90 20
801050 60 3070 4080 5090 60 70
0 80
20 90
40 60 080 20
100 40
120 60
140 0 80
16020
100
18040
120 60
140 80
160100
180 120 140 160 180

Opticap XL
Opticap XL
® Opticap
10 Capsule
Air Flow
XL XL
Rate (Nm
10 Capsules Opticap
10with
Air Capsule
Hydrophobic
XL 10
3 / h)Flow Rate (NmAir
– with
3 / h)
Capsule
Flow Hydrophobic
Opticap
Rate (Nm with Hydrophobic
3 / h)
XLOpticap
Opticap
10 Capsule
Air Flow XL
Rate® Opticap
(Nm10with
Air
XL Capsule
Hydrophobic
XL
XL 10
3 /h)Flow Rate (Nm
10 with
Air Capsule
3 /h)
Capsules
Flow Hydrophobic
RateOpticap
– with Hydrophobic
(Nm3 /h) XLTypes
Opticap
10 Capsule
Air Flow XL(Nm
Rate Opticap
10
with
Air
3/h)
Capsule
Flow
Opticap Hydrophobic
XL
Rate®(Nm 10
with
Air
XL Capsule
3/h)
Flow
10Hydrophobic
with
Rate (Nm 3/h)
Capsules Hydrophobic
–
*Opticap Capsule Connection Types *Opticap Capsule Connection Durapore® CBR 0.1 μm &
Durapore
Hydrophobic
TT
0.22
Durapore
= 38 mm (1 1/2 in.)
µm Membrane,
Durapore 0.22
Durapore
sanitary flange
µm ® Membrane,
FF
0.220.22
Fitting*
inlet and μmµm Membrane,
FFDurapore
Fitting*
outlet; FF = 19 mm (3/4
FF
0.22
Durapore
Fitting*
µm
Hydrophobic Membrane,
0.22
in.) sanitary
Durapore
µm
TTflange
= 38
Membrane,
HH
Durapore
mm
0.22
Fitting*
inlet(1and
µm ®
1/2outlet;
in.)
Membrane,
HHDurapore
0.22 Fitting*
HH = μm
sanitary 14
flange
HH
0.22
Durapore
mm inlet
Fitting*
(9/16and
µm Membrane,
0.22
Durapore
µm
hoseHydrophobic
in.)outlet; FF
barb= 19
Membrane,
inletmm
TT0.22
and(3/4
Fitting*
µmsanitary
outlet
Membrane,
TT Fitting*
in.)Durapore ® TT Fitting*
flange 0.22
inlet andμm
outlet; HH = 14 mm (9/16 in.) hose0.2
barb μm
inlet and outlet
Opticap XL Opticap
10 Capsule XL Opticap
10
with Capsule
Hydrophobic
XL 10with Capsule
Hydrophobic
Opticap
with Hydrophobic
XL Opticap
10 Capsule XL Opticap
10
with Capsule
Hydrophobic
XL 10
with Capsule
Hydrophobic
Opticap
with Hydrophobic
XL Opticap
10 Capsule XL Opticap
10
withCapsule
Hydrophobic
XL 10
with Capsule
Hydrophobic
with Hydrophobic
Membrane,
scfm
FF scfm
Fitting* scfm scfm
Membrane,
scfm
HHscfm
Fitting* scfm scfm
Membrane,scfm
TT Fitting*
Durapore
0.5
0 10.22
0 Durapore
0.5
µm Membrane,
200 301 0.22
0 Durapore
40
0.5
µm Membrane,
200 50FF
1
30 0.22
0 Fitting*
40 µm Membrane,
20 50FF
30Durapore
Fitting*
2.5
0
40 1
500.22
FF
0 Durapore
Fitting*
2.5
µm Membrane,
200 1
30 0.22
0 Durapore
40
2.5
µm Membrane,
200 HH
50
301 0.22
0 Fitting*
40µm Membrane,
20 HH
50
30Durapore
Fitting*
40
0.45
0 HH
500.22
2 0Durapore
Fitting*
µm Membrane,
0.45
400 2
600.22
0Durapore
µm Membrane,
80
40
0.45
0 TT
100
600.22
2 0 Fitting*
80µm Membrane,
40 TT Fitting* TT Fitting*
100
60 80 100
Hydrophobic Durapore®
7 7 7 35 35 35
scfm scfm scfm scfm scfm scfm scfm scfm scfm 6 6 6
0 10
0 PSIG Outlet
200
15 PSIG Inlet
301 0
0 PSIG Outlet
15
40200
PSIG Inlet
0 PSIG Outlet
10 6
5030
15
4020
PSIG Inlet
5030 6
2.0
0
40 10
50
0 PSIG Outlet
6 200
15 PSIG
2.0 Inlet
301 0
0 PSIG Outlet
15
40200
PSIG
2.0 Inlet
0 PSIG Outlet
1 0 30 4020
5030
15 PSIG Inlet
5030
0.40
30 400
0 PSIG
502 0 15
0.40 Outlet
30PSIG
0 PSIG
0.40 Outlet
400Inlet 602 0 15 PSIG
80400Inlet10060
0 PSIG Outlet
2 0 15 PSIG
8040 Inlet 100
60 80 100 0.22 μm
0.4
0.5 0.4
0.5 0.4
0.5 0.35 0.35 0.35 5 5 5
30 PSIG Inlet 30 PSIG Inlet 7 PSIG Inlet
30 7 2.5 2.5
30 7PSIG Inlet
2.5
30 PSIG Inlet 35 PSIG Inlet
30
0.45
35 30
35 0.45
PSIG Inlet 30 0.45
PSIG Inlet 30 PSIG Inlet
Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

0 PSIG Outlet 0 PSIG Outlet

5
6
0 PSIG Outlet
5
6 1.5
5
0 PSIG Outlet
6 1.5
0 PSIG Outlet
25
0 PSIG Outlet
30
250.30
0.40
30
250.30
0 PSIG
0.40Outlet
30PSIG Inlet
0.30
0 PSIG
0.40 Outlet
6
0 PSIG Outlet
415 PSIG Inlet 4
6
4
6
Hydrophobic-hydrophilic
0.3 0.3 0.3 1.5 Inlet 15 15 PSIG Inlet
0.4 15 PSIG
0.4 Inlet
30 PSIG Inlet
15 PSIG
0.4 Inlet
30 PSIG Inlet
415 PSIG Inlet
30 PSIG Inlet
4 2.0 154PSIG
2.0 Inlet
30 PSIG Inlet
15 PSIG
2.0
30 PSIG Inlet
15 PSIG Inlet
20
30 PSIG Inlet
0.25
200.35 200.25
0.35
30 PSIG Inlet 0.25
0.35
30 PSIG Inlet 530 PSIG Inlet 5 5 Durapore® 0.22 μm
Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

Drop (bar)

5 5 5 25 250.20 250.20 0.20 3 3 3

150.30 15 0.30 0.30
PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

PressurePressure

0.2 0.2 0.2 3 3 1.0 3 1.0 1.0 15

0.3 0.3 0.3 1.5 1.5 1.5 4 4 4
4 4 4 20 0.15
200.25 200.15
0.25 0.15
0.25
2 2 2 2 2 2
10 10 10
0.10
0.20 0.10
0.20 0.10
0.20 3 3 3
0.1 0.1 0.1 0.5 3 0.5 0.5
Contact Information
0.2 0.2 0.2 3 3 1.0 1.0 1.0 15 15 15
1 1 1 5 5 0.05 5 0.05 1 1 1
0.15 0.15 0.05
0.15
2 2 2 2 2 2
10 10 10
psid

psid

psid

psid

psid

psid

psid

psid

psid
0.0 0.0 0.0 0 0 0.0 0 0.0 0.0 0 0.00
0 0.10 0 0.00
0.10 0.00
0.10 0 0 0
0.1 0.1 0 40 1050 2060 30
0.1 0.5 0.5 0.5
0 10 20 30 70 0 408010509020160 3070 4080 5090 60
1 0
70 10
80 20 1 30 0 40 1050 2060 3070 0 40801050902060 3070 4080 5090
90 60 700 20 9040 60 0 80 20
80 100 40
120 60 0 80
1 40 1 60
20
100
18040
120
1 60 1 40 80
1 60100180120
1 1 40 1 60 180 1
5 5 0.05 5 0.05 0.05
Air Flow Rate (NmAir
3 / h)
Flow Rate (NmAir
3 / h)
Flow Rate (Nm3 / h) Air Flow Rate (NmAir
3 /h)
Flow Rate (NmAir
3 /h)Flow Rate (Nm3 /h) Air Flow Rate (NmAir
3 /h)
Flow Rate (NmAir
3 /h)Flow Rate (Nm3 /h)
psid

psid

psid

psid

psid

psid

psid

psid

psid
0.0 0.0 0.0 0 0 0.0 0 0.0 0.0 0 0 0.00 0 0.00 0.00 0 0 0
0 10 20 30 040 10 70 0 40
50 2060 30 90 2060 3070 4080 5090 60 70
801050 0 10
80 20
90 30 040 10 70 0 40
50 2060 30 801050
90 2060 3070 4080 5090 60 70 0 80
20 90
40 60 080 20
100 40 1 400 80
120 60 1 60
20
100
18040
120 60
1 40 80
1 60100
180120 1 40 1 60 180

Optiseal Cartridge
Optiseal with
Cartridge
Air Flow Rate Optiseal
(Nm 0.22 µm
Air with
Cartridge
0.22
3 / h)Flow Rate (NmAir Flowµm
3 / h)
with
Rate 10-inch
(Nm 0.22 µm
3 / h)
Cartridge
10-inch
µm with
Cartridge
Air Flow Rate 10-inch
0.22
(NmAir µmwith
Cartridge
0.22
3 /h)Flow Rate (NmAir
3 /h)
µm
Flow with(Nm0.22
Rate 3 /h) Air Flow Rate (NmAir
3 /h)Flow Rate (NmAir
3 /h)
Flow Rate (Nm3 /h)

Hydrophobic Hydrophobic
DuraporeHydrophobic
Membrane
Durapore Membrane
Durapore Hydrophobic
Membrane Hydrophobic
DuraporeHydrophobic
Membrane
Durapore Membrane Durapore Membrane
*Opticap
Optiseal
scfm
®
XL Capsule
Cartridge
Optiseal
scfm
with Connection
Cartridge
Optiseal
0.22 µmwith
scfm
Types
Cartridge
0.22 µmwith
10-inch
0.22 µm
scfm
Cartridge
10-inch with
scfm
Cartridge
10-inch
0.22 µm with
scfm
Cartridge
0.22 µm with 0.22 µm
Hydrophobic
TT = 30 8 2mm4Hydrophobic
Durapore
(1½
6
in.)
80 10 4Hydrophobic
2 12 Membrane
Durapore
Sanitary
14
6 16
80 18
0.28
10
2 204 Membrane
12 Durapore
Flange
14
6 16 10 Hydrophobic
Inlet
8 18 12 Membrane
20
and Outlet
14 16
0 Hydrophobic
18 20
20 Durapore
400 20Hydrophobic
60 Membrane
Durapore
80400 10020 Membrane
60
0.28
Durapore
8040 60 Membrane
100 80 100
0.28 4.0 4.0
0.45 4.0
0.45 0.45 77
FF = 1scfm
9 mm0 (¾ in.)
scfm
PSIG Outlet Sanitary
0 PSIG OutletFlange
scfm
03.5PSIGInlet
Outlet and Outlet
0.40
3.5
scfm
0 3.5
PSIG
scfm
0.40 Outlet 0 PSIG
scfm
0.40 Outlet
6
0 PSIG Outlet
6 6
0 2 4 6 80 102 124 146 1680 18 10
2 20
12
4 14 6 168 18 10 20
12 14 016 18 202015 PSIG400Inlet 6020 15 PSIG
80400Inlet 10060 8040Inlet 100
20 15 PSIG 60 80 100
15 PSIG Inlet 15 PSIG Inlet 15 PSIG Inlet
HH 0.28
= 14 mm30 PSIG(9/16
0.28
Inletin.) Hose
0.28 Barb Inlet
30 PSIG Inlet
4.0 and Outlet
3.0PSIG Inlet
30
0.35
4.0
0.45
3.0
0.35
4.0
303.00.45 Inlet
PSIG 0.35
0.45 Inlet
30 PSIG 5 PSIG Inlet
30 5 5
)rop (bar)

)rop (bar)

)rop (bar)

)rop (bar)

)rop (bar)

)rop (bar)

50 PSIG Inlet 50 PSIG Inlet 50 PSIG Inlet 6 6 6

0 PSIG Outlet 0 PSIG Outlet 3.5
0 PSIG Outlet 0.30
0.40
3.5 0.30
0 3.5
PSIG
0.40Outlet 0.30
0 PSIG
0.40 Outlet 0 PSIG Outlet
2.5 2.5 152.5
PSIG Inlet 15 PSIG Inlet 415 PSIG Inlet 4 4
15 PSIG Inlet 15 PSIG Inlet 15 PSIG Inlet 0.25 0.25
0.35 0.35 Inlet
30 PSIG 30 0.25
0.35 Inlet
PSIG 530 PSIG Inlet 5 5
 4 5 5 25 25 0.30 0.30

Pressure Drop (b

Pressure Drop (b

Pressure Drop (b

Pressure Drop (b

Pressure Drop (b

Pressure Drop (b
0.3 0.3 1.5 1.5 4 4
3 4 4 20 20 0.25 0.25

0.20 0.20 3 3
0.2 0.2 3 3 1.0 1.0 15 15
2
0.15 0.15
2 2 2 2
10 10

Filters Containing Hydrophobic 0.22 μm Durapore Membrane

1
® Durapore® Family Guide
0.5 0.5 0.10 0.10
0.1 0.1
1 1 5 5 0.05 1 1
psid

0.05
0

psid

psid

psid

psid

psid

psid
80 0 0 0.0
0.0 0.0 0.0 0 0 0.00 0.00 0 0
0 10 20 30 0 40 1050 2060 3070 4080 5090 60 70 80 90 0 10 20 30 0 40 1050 2060 3070 4080 5090 60 70 80 90 0 20 40 60 0 80 20100 40120 601 40801 60
100180120 1 40 1 60 180

Typical Liquid Flow Rates and Pressure Drops Air Flow Rate (NmAir
3 / h)
Flow Rate (Nm3 / h) Air Flow Rate (NmAir
3 /h)
Flow Rate (Nm3 /h) Air Flow Rate (NmAir
3 /h)
Flow Rate (Nm3 /h) Overview

ter FlowOptiseal RatesCartridge

at 25 °C
Optiseal with
Cartridge
0.22 µm
with 0.22 µm 10-inch Cartridge
10-inchwith
Cartridge
0.22 µmwith 0.22 µm Selection & Applications Guide
10-inch
rophobic 10-inch Cartridge
HydrophobicHydrophobic
Durapore
Cartridge –Membrane
Hydrophobic
Durapore
with 0.22 µm Membrane Millidisk
Hydrophobic
Hydrophobic
Durapore ®
Cartridge
Membrane – Hydrophobic
Durapore Membrane Formats
Durapore
Hydrophobic
ophilic Filters scfm
®
0.22scfm μm
Durapore
Millidisk® Membrane
Membrane
0.22 μm Hydrophilic Filters scfm Durapore
Millidisk®
scfm
®
0.22
0.22 μm Membrane
μm Hydrophobic Filters
0
0.28gpm
2 4 6
0.28
08 10
2 12
4 14
6 168 18
10 2012 14
4.0
16 18 20
4.00.45
0 20 400
0.45
60
20 80
40 100
60 80 100 OptiScale® Capsules
L/min
0 4 8 L/min12 16 20 6 6
12 14 16 18 20 1.40
22 0 PSIG Outlet
15 PSIG
0
50 Inlet
100 PSIG Outlet
20
15 PSIG Inlet
3.5
30
20 40 3.50.40
50 0 PSIG
0.40 0Outlet5
15 PSIG
50 Inlet
010PSIG15
Outlet 20
15 PSIG Inlet
25 30 35 Cartridge Filters
40 0.35 30 0.35
PSIG Inlet 30 PSIG Inlet 5 5
18
3.0 3.0

Drop (psid)
30 PSIG Inlet 30 PSIG Inlet
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

(bar)
Differential Pressure (psid)

Cartridges
45 45 3.0
3.0 50 PSIG Inlet 50 PSIG Inlet 3.0
0.30 0.30
16
1.05 40 2.5 2.5 40 4 4
Pressure Drop (bar)

Pressure
30 2.5 14 0.25
2.5 0.25 2.5
0.14 0.1435 2.0
12
2.0
0.20
35
0.20
30
3 3 Optiseal® Cartridges

Pressure
30 2.0
0.70
2.0 1.5
10 1.5 2.0

Differential
0.15 0.15
Millidisk® Cartridges
20 25 25 2 2
1.5 81.01.00.10
1.5 1.5
20 20
0.10
6 15 1 MCGB 10S 02 1
MCVL 10S 03 0.35 1.0 15 0.5 MCGL 10S 030.50.05
1.0 0.05 1.0
10 MCGB 20S 02
MCVL 20S 03 4 MCGL 20S 03
psid psid

psid

psid

psid
10
MCVL 30S 03 0.0 0.010 0.0 MCGL 30S 030.00.00 0.00 0 MCGB 30S 01 0 0.5
MCVL 40S 03
0.50 70 140 21050 70 350
280 1 4 0 420
210490 6 02 420 490
280 5350 560 0.50
MCGL 40S 03 20 40 60
5 0 80 20100 40120 60140 80160100
180 120 140
MCGB160
40S 180
01 Capsule Filters
psid

0 0.00 Air Flow Rate (L/min) 0

Air Flow Rate (L/min)

bar
Air 0Flow Rate (Nm
Air
3 /h)
Flow Rate (Nm3 /h)
bar
0.0
bar

0.0 0 0.0
Opticap® XL and XLT Capsules
0 0 10 20 30 40 50 60 70 80
3 4 5 6 0 2 4 6 8 10 12 14 0 1 2 3 4 5 6 7 8 9 10
Water Flow Rate (L/min)
Flow Rate (L/min)
e (L/min)
Typical Liquid
Typical
Flow
Liquid
RateFlow
andRate
Pressure
and Pressure
Drop Drop Flow Rate (L/min)

Opticap ®
XL 5 Capsules
Opticap XLOpticap
5 Capsule
XL with – Hydrophobic
5 Capsule
Hydrophobic
with Hydrophobic Opticap
Opticap XLOpticap XL XL
®
10 Capsule10 10Hydrophobic
with Capsules
Capsule –10-inch
Hydrophobic
with HydrophobicCartridge
10-inchwith
Cartridge
0.22 µm
with 0.22 µm
Filters for Final Filtration
et and outlet; Durapore
HH = 14 mm (9/16 in.) hose
0.22 μmbarb inlet and outlet
Membrane Durapore 0.220.22 μm Membrane
® ®
Durapore 0.22
Durapore
µm Membrane
0.22 µm Membrane Durapore 0.22 Durapore
µm Membrane
µm Membrane Hydrophobic
Hydrophobic
Durapore Membrane
Durapore Membrane Millipak® Final Fill Capsules
gpm gpm gpm gpm gpm gpm
philic Filters 0 5 Millidisk®
0 10 5.0 μm Hydrophilic
5 15 10 20 15 Filters
20 0 5
Millidisk®
0 10
0.22
5 15
μm 10
Hydrophobic
20 15
Filters
20 0 4 80 12
4 168 20
12 16 20 M
 illidisk® Barrier Cartridges
3.0 3.0 3.0 Air3.0Flow Rate @ 25 ºC 1.40 1.40 20 20
TT TT
40 40
TT TT
40 40
18 18
and Millipak® Barrier Capsules
2.5 FF 2.5 FF 2.5 FF 2.5 L/min FF
HH L/min HH 16 16
HH HH
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

50 60 70 1.05 1.05

Pressure Drop (bar)

Pressure Drop (bar)

0 10 20 30 40 30 50 60 7030 0 200 400 600 800 1000 1200 1400
2.0 2.050 30 30 14 14
2.0 2.0
10 .7
12 12
Durapore® 0.1 μm & 0.22 μm
Differential Pressure (psid)

Differential Pressure (psid)

3.0 45 MCSL 10S 02

1.5 1.5
3.0
MCSL 20S 02
40 20 20 1.5 1.5
8 20
0.70
20
0.70 10 10
2.5 MCSL 30S 01
1.0 1.035
MCSL 40S 01
1.0
2.5
1.0
8
6
8
6
Durapore® 0.45 μm
2.0 30 2.0 6
10 10 10 100.35 0.35
0.5
1.5
0.525 0.5
1.5
0.5
MCGB 10
.35
4
2
4
2
Durapore® 5.0 μm
20 4
psid

psid

psid

psid

psid

psid
Multimedia Durapore®
MCHL 10S 03 0.0 0.0 0 0 0.0 0.0 0 MCGB 20 0 0.00 0.00 0 0
1.0 15 1.0
0 10 20 300 410
0 50
20 630
0 704 0 850
0 60 70 80 0 10 20 300 10
40 50
20 30
60 70
40 50
80 60 70 0 10 20 300 40
10 50
20 60
30 70
40 80
50 60 70 80
MCHL 20S 03 MCGB80
30
MCHL 30S 03 10 2
0.5 Water Flow Rate Water
(L/min)Flow Rate (L/min) Water Flow Rate Water
(L/min)Flow Rate (L/min) Water Flow Rate Water
(L/min)Flow Rate (L/min)
Charged Durapore® 0.22 μm
MCHL 40S 03 0.5 MCGB 40
5
bar

0.0
bar
bar

0 0.0 0 0
Multilayer Durapore®
12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20 0 10 20 30 40 50
/min)
*Opticap XL*Opticap
CapsuleXL
Connection
Capsule Connection
Types Types
Flow Rate (L/min) Air Flow Rate (SCFM)
TT = 38 mm (1
TT1/2
= 38
in.)mm
sanitary
(1 1/2flange
in.) sanitary
inlet and
flange
outlet;
inlet
FFand
= 19
outlet;
mm (3/4
FF =in.)
19sanitary
mm (3/4flange
in.) sanitary
inlet and
flange
outlet;
inlet
HHand
= 14
outlet;
mm HH (9/16
= 14
in.)mm
hose
(9/16
barbin.)
inlet
hose
andbarb
outlet
inlet and outlet
Durapore® CBR 0.1 μm &
0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

78
Filters Containing Hydrophobic 0.22 μm Durapore® Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Cartridge Filters Formats
OptiScale® Capsules
Cartridge Filters
C V G B T P 3
Cartridges
Optiseal® Cartridges
Cartridge Pore Size Cartridge Length Quantity per pkg.
Filter
Millidisk® Cartridges
GB = H
 ydrophobic 1 = 10-inch 3 = 3/pk
Durapore® 0.22 µm 2 = 20-inch
3 = 30-inch Capsule Filters
Media Type Cartridge Code Connection Type
5 = 5-inch Opticap® XL and XLT Capsules
V=H
 ydrophobic 0 = (2-222) O-ring TP = With prefilter
Durapore® 5 = (2-222) O-ring with spear assembly
7 = (2-226) O-ring with locking outlet Filters for Final Filtration
and spear assembly Millipak® Final Fill Capsules
Optiseal® Cartridge Filters M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

L A G B 0 4 T P 6 Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Cartridge Pore Size Cartridge Length Quantity per pkg. Durapore® 5.0 μm
Filter
GB = H
 ydrophobic 4 = 4-inch 6 = 6/pk
Durapore® 0.22 µm
Multimedia Durapore®

Media Type Cartridge Code Connection Type

Charged Durapore® 0.22 μm
A = Hydrophobic Durapore® 0 = (2-222) O-ring TP = With prefilter Multilayer Durapore®
Durapore® CBR 0.1 μm &
Millidisk® Cartridge Filters 0.2 μm
Hydrophobic Durapore®
0.22 μm
M C G B 0 Hydrophobic-hydrophilic
Durapore® 0.22 μm
Millidisk® Pore Size Millidisk® Stack Size Package Quantity
Cartridges 40S = 40-stack
GB = H
 ydrophobic 2= 2  per package Contact Information
Durapore® 0.22 μm 30S = 30-stack (Millidisk® 10, 20)
20S = 20-stack 1 = 1 per package
10S = 10-stack (Millidisk® 30, 40)

79
Filters Containing Hydrophobic 0.22 μm Durapore® Membrane Durapore® Family Guide

Ordering Information Overview

Selection & Applications Guide
Formats
Opticap® XL Capsule Filters
OptiScale® Capsules
Cartridge Filters
K V G B A 1 Cartridges
Optiseal® Cartridges
Opticap® XLT Pore Size Capsule Sizes Quantity per pkg. Millidisk® Cartridges
Capsule Filter
GB = H
 ydrophobic 05 = Opticap XL 5
®
1 = 1/pk
Durapore® 0.22 μm 10 = Opticap® XL 10
Capsule Filters
Opticap® XL and XLT Capsules
Media Type May be Connection Type
Autoclaved
V = Hydrophobic TT = 38 mm (1½ in.) Sanitary Flange Inlet and Outlet
Durapore® FF = 19 mm (¾ in.) Sanitary Flange Inlet and Outlet Filters for Final Filtration
HH = 14 mm (9/16 in.) Hose Barb Inlet and Outlet Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Millipak® Final Fill Capsule Filters

Durapore® 0.1 μm & 0.22 μm
Durapore® 0.45 μm
M F G B 3 Durapore® 5.0 μm
Multimedia Durapore®
Millipak® Final Pore Size Quantity per pkg. Charged Durapore® 0.22 μm
Fill Filter
GB = H
 ydrophobic 3 = 3/pk
Durapore® 0.22 μm
Multilayer Durapore®
Durapore® CBR 0.1 μm &
Millipak® Final Fill Filter Series 0.2 μm
02G = 20, non-sterilized
Hydrophobic Durapore®
02S = 20, sterilized by gamma radiation Connection Type
0.22 μm
06G = 60, non-sterilized Millipak® Final Fill 20, 60
06S = 60, sterilized by gamma radiation H = 6 mm (1/4 in.) Stepped Hose Barb Inlet and Outlet Hydrophobic-hydrophilic
20G = 200, non-sterilized Millipak Final Fill 200
® Durapore® 0.22 μm
20S = 200, sterilized by gamma radiation B = 13 mm (1/2 in.) stepped hose barb inlet and outlet
Millipak® Final Fill 60, 200 Contact Information
T = 38 mm (1½ in.) sanitary flange inlet and outlet

80
Barrier Filters Containing Durapore 0.22 μm ® Durapore® Family Guide

Hydrophilic-Hydrophobic Membrane Overview

Selection & Applications Guide
For pre-use integrity testing of sterile filtration systems Formats
OptiScale® Capsules
Cartridge Filters
Filters containing these membranes Cartridges
are designed to simplify in-line pre- Optiseal® Cartridges
use integrity testing of sterile filtration Millidisk® Cartridges
systems. The stacked disc design contains
layers of sterilizing-grade hydrophilic Capsule Filters
and hydrophobic Durapore® 0.22 µm Opticap® XL and XLT Capsules
membranes creating a permeable barrier
which allows sterile flow of liquid and gas. Filters for Final Filtration
Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Benefits Durapore® 0.45 μm
These barrier filters simplify wetting, flushing and Durapore® 5.0 μm
integrity testing of upstream sterilizing filters in
Multimedia Durapore®
filtration assemblies while maintaining the system
sterility and removing the constraint of a flush bag Charged Durapore® 0.22 μm
or can. Multilayer Durapore®
Durapore® CBR 0.1 μm &
Filter Formats 0.2 μm
Hydrophobic Durapore®
• Millipak® 200 Barrier capsule filter 0.22 μm
• Millidisk® 40 Barrier cartridge filter Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

81
Barrier Filters containing Hydrophilic-Hydrophobic Durapore® 0.22 μm Membranes Durapore® Family Guide

Specifications Overview
Selection & Applications Guide
Description Millidisk® 40 Barrier Cartridge Millipak® 200 Barrier Capsule
Formats
Materials of Construction
Membrane: Hydrophilic and Hydrophobic Durapore® Hydrophilic and Hydrophobic Durapore® OptiScale® Capsules
PVDF membrane PVDF membrane
Structural components/Housing: Polysulfone Polycarbonate Cartridge Filters
O-rings: Silicone — Cartridges
Filtration Area 2000 cm2 (310 in2) 1000 cm2 (1.08 ft2)
Optiseal® Cartridges
Maximum Differential Pressure
Forward: 4.1 bar (60 psid) at 25 °C, 1.7 bar (25 psid) at 80 °C 4.1 bar (60 psi) at 25 °C, 1.7 bar (25 psi) at 80 °C Millidisk® Cartridges
Reverse: 690 mbar (10 psid) at 25 °C 690 mbar (10 psid) at 25 °C
Maximum Recommended The maximum forward differential pressure during this operation should not exceed Capsule Filters
Operational Pressure 0.5 bar (7.25 psid) at 25 °C to prevent wetting of hydrophobic membrane.
Opticap® XL and XLT Capsules
Sterilization May be autoclaved at 135 °C for 60 minutes May be autoclaved at 123 °C for 90 minutes
up to 4 times or steamed-in-place at 135 °C up to 3 times; not in-line steam sterilizable
for 60 minutes up to 4 times Filters for Final Filtration
Bubble Point at 23 °C ≥ 1280 mbar (18.5 psi) in 70/30% IPA/water at 23 °C Millipak® Final Fill Capsules
Bacterial Endotoxin An aqueous extraction contains < 0.5 EU/mL bacterial endotoxin as determined by the LAL test. This meets the
requirements of USP <85>.
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules
Toxicity Component materials meet the requirements of Component materials meet the requirements of USP
USP <88> Biological Reactivity Tests for Class VI Plastics. <88> Biological Reactivity Tests for Class VI Plastics.
Oxidizable Substances These filters meet the requirements of the USP WFI Oxidizable Substance requirements after a water flush of Durapore® 0.1 μm & 0.22 μm
200 mL.
Durapore® 0.45 μm
Bacterial Retention Quantitative retention of 10⁷ CFU/cm² Brevundimonas diminuta ATCC® 19146 per ASTM® F838 methodology.
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Ordering Information Multilayer Durapore®
Durapore® CBR 0.1 μm &
Description Qty/Pk Cat. No.
0.2 μm
Millidisk® Barrier Cartridge Filter
Hydrophobic Durapore®
Millidisk® 40 Barrier Filter 3 MCGBL4S03 0.22 μm
Millipak® Barrier Capsule Filters
Hydrophobic-hydrophilic
Millipak® 200 Barrier Filter with Hosebarb 3 MSP010012 Durapore® 0.22 μm
Millipak® 200 Barrier Filter with 1 1/2 in. TC 3 MSP010013

Contact Information

82
 Durapore® Family Guide

Overview
Selection & Applications Guide
Formats
OptiScale® Capsules
Cartridge Filters
Cartridges
Optiseal® Cartridges
For additional information, visit Millidisk® Cartridges
MerckMillipore.com

To place an order or receive technical assistance, visit Capsule Filters

MerckMillipore.com/contactPS Opticap® XL and XLT Capsules

Filters for Final Filtration

Millipak® Final Fill Capsules
M
 illidisk® Barrier Cartridges
and Millipak® Barrier Capsules

Durapore® 0.1 μm & 0.22 μm

Durapore® 0.45 μm
Durapore® 5.0 μm
Multimedia Durapore®
Charged Durapore® 0.22 μm
Multilayer Durapore®
Merck KGaA
Frankfurter Strasse 250
Durapore® CBR 0.1 μm &
64293 Darmstadt, Germany 0.2 μm
Hydrophobic Durapore®
0.22 μm
Hydrophobic-hydrophilic
Durapore® 0.22 μm

Contact Information

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved. Merck, the vibrant M, Millipore, Durapore, Lifegard, Milligard, Opticap, OptiScale, Polysep,
Viresolve, Millidisk, Optiseal, Aerex, Aervent, Millipore Express, Emprove, Millipak, Mobius and Sigma-Aldrich are trademarks of Merck KGaA, Darmstadt, Germany or its
affiliates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.
Lit. No. MK_PG5075EN Ver. 1.0 35675 04/2021 83