Europäisches Patentamt

(19) European Patent Office *EP000845977B1*

Office européen des brevets (11) EP 0 845 977 B1
(12) EUROPEAN PATENT SPECIFICATION

(45) Date of publication and mention (51) Int Cl.7: A61K 7/32, A61K 7/00
of the grant of the patent:
02.05.2003 Bulletin 2003/18 (86) International application number:
PCT/US96/12773
(21) Application number: 96927317.6
(87) International publication number:
(22) Date of filing: 15.08.1996 WO 97/006777 (27.02.1997 Gazette 1997/10)

(54) CLEAR COSMETIC GEL COMPOSITION

KLARE KOSMETISCHE GELZUSAMMENSETZUNG
COMPOSITION DE GEL COSMETIQUE TRANSPARENTE

(84) Designated Contracting States: • HILLIARD, Peter R., Jr.

AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT Far Hills, NJ 07931 (US)
SE
(74) Representative:
(30) Priority: 18.08.1995 US 2509 Smulders, Theodorus A.H.J., Ir. et al
Vereenigde
(43) Date of publication of application: Postbus 87930
10.06.1998 Bulletin 1998/24 2508 DH Den Haag (NL)

(73) Proprietor: Colgate-Palmolive Company (56) References cited:

New York, N.Y. 10022 (US) EP-A- 0 373 499 WO-A-91/08732
WO-A-92/05767 GB-A- 2 283 914
(72) Inventors: US-A- 4 822 620
• LEE, Wilson
Bloomfield, NJ 07003 (US) Remarks:
• POTECHIN, Kathy The file contains technical information submitted
Short Hills, NJ 07078 (US) after the application was filed and not included in this
• BIANCHINI, Robert J. specification
Belle Mead, NJ 08502 (US)
EP 0 845 977 B1

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give
notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in
a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art.
99(1) European Patent Convention).

Printed by Jouve, 75001 PARIS (FR)

 EP 0 845 977 B1

Description

Technical Field

5 [0001] The present invention is directed to a clear cosmetic gel composition (for example, a clear soft gel antiper-
spirant composition) that is a water-in-oil emulsion. The composition of the present invention can include deodorant
and/or antiperspirant active materials, to combat body malodor, for example, in axillary regions of the human body, by
applying the composition to the human body (for example, to the skin, in axillary regions of the body).
[0002] The present invention is particularly directed to cosmetic gel compositions, including antiperspirant and de-
10 odorant gel compositions, that have reduced whitening and tack, and reduced skin irritation, and which can include
increased amounts of the cosmetically active ingredient (for example, increased amounts of antiperspirant active in-
gredient), and can include other commercially beneficial materials, yet which can be provided as a clear gel product.

Background Art
15
[0003] Antiperspirant products are well known in the art. Antiperspirants have appeared in the marketplace in varied
dosage forms, such as sticks, soft solids, soft gels, roll-on, aerosols and creams. Generally, these dosage forms include
a solution of the active ingredient in a suitable solvent, a suspension of the active ingredient in a non-solvent, or a
multiphasic dispersion or emulsion in which a solution of the active ingredient is dispersed in some continuous phase
20 or in which the solubilized active ingredient constitutes a continuous phase.
[0004] Of the above-referred-to dosage forms, the stick form is an example of a solid form, and the soft solid and
soft gel are thickened forms which may or may not be solid (for example, under some circumstances, gels can flow).
The stick form can be distinguished from a soft solid or soft gel in that, in a stick, the formulated product can retain its
shape for extended time periods outside the package, the product not loosing its shape significantly (allowing for some
25 shrinkage due to solvent evaporation). Adjustment of amounts of gelling or thickening agents can be used in order to
form a soft gel or stick.
[0005] Soft gels or soft solids can be suitably packaged in containers which have the appearance of a stick, but
which dispense through apertures (for example, slots or pores) on the top surface of the package. The soft solid products
have also been called soft sticks or "smooth-ons", and hereinafter are generically called "soft solids". Reference is
30 made to US-A-5,102,656, US-A-5,069,897, and US-A-4,937,069, each of which discloses such soft solids, including
physical characteristics thereof such as viscosity and hardness.
[0006] Recently, there has been significant activity in developing clear and translucent antiperspirant sticks and soft
gels, particularly to provide sticks and soft gels having increased efficacy (for example, by providing increased amounts
of the antiperspirant active in the sticks and soft gels), improved cosmetic characteristics (including reduced whitening,
35 reduced residue and reduced tack), and reduced skin irritation potential (e.g., providing a product that is "mild") .
[0007] Clear or translucent antiperspirant sticks consisting essentially of a solution of the active antiperspirant ma-
terial in a polyhydric alcohol vehicle, gelled by dibenzylidene monosorbitol acetal, have been disclosed. Since the
gelling agent is inherently unstable in an acidic environment, and since conventional active antiperspirant materials
are acidic, much work has been involved in discovering suitable stabilizing or buffering agents to prevent or slow down
40 acid attack on the acetal gelling agent. Such work has not been completely successful. Moreover, these clear or trans-
lucent antiperspirant sticks, containing the acetal gelling agent and including a solubilized active antiperspirant material,
have the disadvantage of being inherently tacky. Thus, development work in connection with these clear or translucent
antiperspirant sticks containing the acetal gelling agent has focused on discovering suitable anti-tack agents for this
dosage form. However, since acid hydrolysis of the gelling agent occurs more rapidly in aqueous solutions, formulators
45 have been forced to avoid using water in the formulations. This severely restricts the ability of the formulator to develop
cosmetically elegant formulations which are simultaneously chemically stable, optically clear, low in tack, low in residue
and which have acceptable application aesthetics.
[0008] Various other gelling agents have been utilized in antiperspirant and deodorant products. For example, clear
stick deodorant compositions have been available for some time. The clear deodorant sticks are generally produced
50 by using stearate soaps as gelling agents for an alcoholic or glycolic solution of an antimicrobial agent and a fragrance.
These deodorant products offer no antiperspirant protection (that is, these deodorant products do not reduce flow of
perspiration from a human). Conventional antiperspirant active ingredients, which are acidic, are not ordinarily used
with stearate soap gelling agents, because they are incompatible with the stearate soap gelling agents, due to the
chemical interaction between the antiperspirant active material and the soap and consequent inactivation of the anti-
55 perspirant active material.
[0009] Gelling, for cosmetic compositions, may also be achieved through the use of cellulosic or algin-derived pol-
ymer materials. Most of these materials are incompatible with conventional antiperspirant active ingredients, at levels
of the antiperspirant active ingredients required to obtain antiperspirant efficacy. Moreover, the polymer materials are

2
 EP 0 845 977 B1

unstable at the low pH normally encountered in antiperspirant products.

[0010] Concerning wax and soap-gelled sticks, see each of US-A-4,382,079, US-A-4,414,200, US-A-4,280,994,
US-A-4,265,878 , US-A-3,259,545, US-A-2,970,083, US-A-2,933,433, US-A-2,900,306, US-A-2,857,315, and US-A-
4,383,988.
5 [0011] US-A-4,948,578 discloses a transparent antiperspirant stick which is an oil-in-water emulsion, containing spe-
cific amounts of an antiperspirant effective aluminum salt, a nonionic surfactant which is a C11-C18 fatty alcohol alkox-
ylated with from about 10 to about 20 moles ethylene oxide, a liquid oil immiscible with water, and water, the composition
being free of any wax matrix. Illustratively, aluminum chlorhydrate is the antiperspirant salt, the nonionic surfactant is
a C11-C18 alcohol ethoxylate, and the liquid oil component may be selected from emollient oils, volatile silicones and
10 mixtures of these materials.
[0012] US-A-4,944,938 discloses clear, non-alcoholic, quick drying, antiperspirant and deodorant gels, which are
stable both at room temperatures and at higher temperatures, are non-stinging and leave no white residue on the skin,
the gel not including gelling agents, waxes, clays, or monohydric alcohols having 2-8 carbon atoms. The gels use 3-5
carbon atom trihydric alcohols as coupling agents, these alcohols acting as solublizers in the system and keeping the
15 system stable and clear. The gels can include an aluminum active salt; a volatile water-insoluble emollient, such as
isostearyl benzoate; a soluble emollient such as cetyl ether; solubilizers such as propylene glycol and glycerine; volatile
siloxanes; and water.
[0013] Some cellulosic materials, such as hydroxypropylcelluouse, among others, are compatible with polyvalent
metal salts and have been used in the manufacture of clear lotions. These cellulosic materials, however, must be
20 prepared with a high percentage of water or alcohol in order to insure solubilization of the active ingredient. The resulting
formulations, in addition to a high irritation potential, are tacky and pituitous, and low in efficacy, when alcohol-based;
and exhibit tackiness and a long drying time when water-based.
[0014] Clear or translucent antiperspirant soft gels (which have been dispensed from containers having the appear-
ance of stick) have recently been marketed, consisting of viscous high-internal-phase emulsions. These soft gels exhibit
25 some advantages over the aforementioned sticks, particularly acetal-based clear sticks, in that the selection of formu-
lation ingredients is less restricted (for example, water can be used), and often tack can be reduced significantly.
Concerning these emulsions, note US-A-4,673,570 and US-A-4,900,542. These two U.S. patents disclose clear gelled
antiperspirant compositions free of waxes and conventional gelling agents, containing a volatile silicone fluid, a silicone
emulsifier, a destablizing auxiliary emulsifier, water, non-volatile emollient, a coupling agent, an active antiperspirant
30 component and ancillary agents such as perfume, coloring agents, etc. The silicone emulsifier is a cyclomethicone-
dimethicone copolyol silicone fluid marketed by Dow Corning Corp. under the trademark DOW CORNING 3225C for-
mulation.
[0015] Also to be noted is WO 92/05767. This patent document discloses a clear gel-type cosmetic product having
a viscosity of at least 50,000 cps at 21°C and a refractive index of 1.3975-1.4025 at 21°C, and having an optical clarity
35 better than 50 NTU (Nephelometric Turbidity Units) at 21°C, the product being an emulsion with a water phase having
an active ingredient incorporated therein and with an oil phase. The refractive indices (measured at 5893Å) of the
water and oil phases match to within 0.0004. The oil phase includes an emulsifier which when properly mixed with the
water phase component yields a water-in-oil emulsion, and the water phase includes one or a combination of various
polar species such as water, propylene glycol, sorbitol and ethanol. The water phase includes the deodorant and/or
40 antiperspirant active ingredient. The contents of this PCT (International application) Publication No. 92/05767 are in-
corporated herein by reference in their entirety.
[0016] In GB-A-2 283 914 antiperspirant compositions based on a water-in-oil emulsion comprising a long chain
hydrocarbon modified polydiorganosiloxane-polyoxyalkylene copolymer containing polydimethylsiloxy groups, water,
an astringent salt, a solubilizing agent such as isopropyl palmitate, a volatile liquid such as a methylsiloxane fluid or
45 an organic fluid with a boiling point below 250°C, and a refractive index adjuster such as propylene glycol or sorbitol
are described.
[0017] European Patent Specification Publication No. 0 373 499 B1 to Potini describes a clear non-alcoholic, quick
drying, highly active, antiperspirant and deodorant gel. The compositions comprise volatile siloxanes and use polyhydric
alcohols as solubilizers.
50 [0018] PCT (International application) Publication No. 91/08732 to Kwass describes an optically clear liquid antiper-
spirant roll-on product in the form of a stable water-in-oil emulsion. Examples of stabilizing agents include a polyalkox-
ylated alcohol and a lower alcohol having a molecular weight less than the polyalkoxylated alcohol.
[0019] While various cosmetic gel compositions, including antiperspirant and deodorant compositions, that are clear,
are known, it is still desired to provide a clear cosmetic gel composition (e.g., clear antiperspirant and/or deodorant
55 gel composition) having an increased amount of cosmetically active material (e.g., antiperspirant agent) and also having
other materials providing advantageous cosmetic effects in the composition, while maintaining a clear composition;
having reduced whitening and tack; and which is mild and has reduced skin irritation potential relative to commercially
available products.

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Disclosure of the Invention

[0020] It is a first object of the present invention to provide a clear cosmetic gel composition (for example, a clear
deodorant and/or antiperspirant gel composition) having increased amounts of cosmetically active ingredient (for ex-
5 ample, deodorant active and/or antiperspirant active ingredients) therein, and a packaged product containing such
cosmetic gel composition.
[0021] It is a further object of the present invention to provide a clear cosmetic gel composition and packaged product,
wherein additional components, or additional amounts of these components, providing improved cosmetic effects, can
be incorporated in the composition, while still maintaining a clear composition.
10 [0022] It is a further object of the present invention to provide a clear cosmetic (e.g., deodorant and/or antiperspirant)
gel composition and packaged product, wherein the composition is mild (has lower skin irritation potential) as compared
with commercially available products.
[0023] It is a further object of the present invention to provide a clear cosmetic (e.g., deodorant and/or antiperspirant)
gel composition and packaged product, which has reduced residue, and causes a reduced amount of whitening after
15 application.
[0024] It is a still further object of the present invention to provide a clear cosmetic (e.g., deodorant and/or antiper-
spirant) gel composition, and packaged product, which has improved cosmetic characteristics, including reduced tack-
iness after application.
[0025] It is a still further object of the present invention to provide a clear cosmetic (e.g., deodorant and/or antiper-
20 spirant) soft gel composition, and packaged product, which has an increased amount of active material while main-
taining clarity, which has reduced whitening and residue, and which has reduced tack.
[0026] It is a still further object of the present invention to provide a clear cosmetic (e.g., deodorant and/or antiper-
spirant) gel composition, based on water-in-silicone oil emulsions, having increased amounts of cosmetically active
ingredients therein while maintaining clarity, which is mild (has low skin irritation potential) as compared with commer-
25 cially available products, and which has reduced whitening and residue, and decreased tackiness, after application.
[0027] It is a still further object of the present invention to provide a clear cosmetic (e.g., deodorant and/or antiper-
spirant) gel composition, based on water-in-silicone oil emulsions, having increased amounts of cosmetically active
ingredients therein, and also having additional components (and/or additional amounts of other components) in the
water and/or oil phase of the emulsion providing advantageous cosmetic effects (e.g., reduced whitening and reduced
30 tack, silkier feel and a cool sensation, etc.), while maintaining clarity.
[0028] It is a still further object of the present invention to provide a method of forming, and of using, the clear cosmetic
(e.g., deodorant and/or antiperspirant) gel compositions as discussed in connection with the foregoing objects.
[0029] According to a first aspect of the present invention, various of the foregoing objects are achieved through a
clear and mild cosmetic gel composition comprising (1) an aqueous phase containing water, at least one cosmetically
35 active ingredient in an amount sufficient to have a cosmetic effect, and a glycol, and (2) an oil phase containing a
material having a refractive index in the range of 1.40 to 1.50, the composition further including (3) 10-30% of at least
one coupling agent to bring the aqueous phase and the oil phase into a homogeneous composition (that is, the at least
one coupling agent causes the aqueous phase to be uniformly distributed throughout the oil phase) and (4) an alkox-
ylated, alkyl substituted siloxane surface active agent in an amount sufficient to form the composition into a water-in-
40 oil emulsion, the composition being a water-in-oil emulsion and having a refractive index (prior to addition of fragrance)
in a range of from 1.4026 to 1.4150, characterized in that the glycol is at least one polypropylene glycol and the alkox-
ylated, alkyl substituted siloxane surface active agent is a dimethicone copolyol. Preferably, the refractive index of the
composition is in a range of from 1.4050 to 1.4150, especially from 1.4050 to 1.4085, and most preferably the refractive
index of the composition is a range of from 1.4060 to 1.4080. Refractive index measurements were made using a
45 Bausch and Lomb Abbe 3L Refractometer.
[0030] Addition of fragrance to the gel composition according to the present invention may increase the refractive
index of the finished product. The refractive index referred to previously (e.g., a broadest range of 1.4026 to 1.4150)
is the refractive index prior to incorporating fragrance in the composition.
[0031] By providing a composition having the specified refractive index, a composition containing more of the cos-
50 metically active ingredients (in particular, more of the antiperspirant active ingredient such as an antiperspirant active
salt, where the composition is a clear antiperspirant gel composition) can be achieved.
[0032] Moreover, this composition having the specified refractive index can also include high refractive index com-
ponents, in either the oil phase or the aqueous phase, or additional amounts of high refractive index components, that
provide advantageous cosmetic or other aesthetic effects. That is, conventional clear compositions have a relatively
55 low refractive index. These relatively low refractive indices of conventional clear compositions of the water-in-oil emul-
sion type are due at least in part to the relatively low refractive indices of various conventionally used silicone fluids
(e.g., around 1.3995), incorporated in the oil phase of these conventional compositions. This limits materials (and
amounts) that can be included in the conventional composition such that the emulsion as a whole has the required

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relatively low refractive index. This limitation can be avoided according to the present invention, providing an increased
degree of freedom in the choice of materials that can be incorporated in both the aqueous and oil phases of the com-
position of the present invention. For example, emollients having a higher refractive index can be incorporated in the
oil phase and in the water phase, especially in the oil phase, of compositions according to the present invention, having
5 the relatively high refractive index. Since antiperspirant active materials generally have high refractive indices, these
can be incorporated in larger amounts in compositions of the present invention. Moreover, materials having a high
refractive index, that can reduce tack and whitening of the composition, can be incorporated in the oil phase of the
composition of the present invention.
[0033] Desirably, the composition according to the present invention has at least near refractive index matching
10 between (1) the aqueous phase and at least one coupling agent, on the one hand, and (2) the oil phase and alkoxylated,
alkyl substituted siloxane surface active agent, on the other. In particular, preferably, according to the present invention,
a difference between the refractive index of (1) the aqueous phase and at least one coupling agent, and (2) the oil
phase and alkoxylated, alkyl substituted siloxane surface active agent, is less than 0.0005.
[0034] Compositions according to the present invention can be clear. For example, illustratively, the composition
15 according to the present invention has an optical clarity better than approximately 50 NTU (Nephelometric Turbidity
Units) at room temperature (20°-25°C), preferably having a turbidity measurement of less than approximately 30 NTU,
more preferably less than approximately 20 NTU. Turbidity measurements as discussed in the foregoing and discussed
hereinafter, were made with an Orbeco-Hellige #965 Direct-Reading Turbidimeter.
[0035] Where the cosmetic gel composition of the present invention includes an antiperspirant active agent as the
20 cosmetically active ingredient, with such agent being incorporated in the composition in an amount sufficient to reduce
flow of perspiration when the composition is applied to a human, a clear antiperspirant gel composition can be formed.
Various conventional antiperspirant active aluminum-containing salts, including (but not limited to) aluminum chlorhy-
drate and aluminum zirconium tetrachlorohydrex gly, can be utilized as the antiperspirant active agent. Thus, a clear
antiperspirant gel composition can be achieved, according to the present invention.
25 [0036] The composition according to the present invention can be a soft gel, for example, having a viscosity in a
range from 75,000 - 350,000 mPa.s (75,000 cps to 350,000) at room temperature (20°-25°C). Such a soft gel can be
incorporated in conventional dispensing packages (for example, dispensing packages having slots or pores on the top
thereof for extruding the gel to the upper surface, for rubbing the composition on the skin from such upper surface).
[0037] Desirably, the oil phase of the cosmetic gel composition according to the present invention includes a volatile
30 silicone fluid, a non-volatile silicone fluid and an emollient. Preferably, such emollient, which can be a silicone material
(such as phenyl trimethicone), is the material of the oil phase having the high refractive index, and has a refractive
index higher than that of the volatile silicone fluid and higher than that of the non-volatile silicone fluid (that is, this
emollient is, desirably, a high refractive index emollient compatible with the silicone fluids of the oil phase).
[0038] According to another aspect of the present invention, the aqueous phase of the clear cosmetic gel composition
35 further includes at least one polypropylene glycol. Illustratively, tripropylene glycol can be utilized as the polypropylene
glycol. According to this aspect of the present invention, propylene glycol can be used in combination with the poly-
propylene glycols. Incorporation of the polypropylene glycol in the gel composition improves cosmetic properties, in-
cluding a reduction of tack and a decrease in the whitening and in the residue after application of the composition.
Moreover, compositions incorporating polypropylene glycol, particularly, tripropylene glycol, have improved mildness
40 (that is, reduced skin irritation potential) relative to commercially available products.
[0039] The objectives according to the present invention are also achieved through the method of forming the clear
and mild cosmetic gel composition according to the present invention. In this method, an aqueous-based phase com-
prising water; at least one cosmetically active ingredient in an amount sufficient have a cosmetic effect; and at least
one coupling agent in an amount of 10-30%, drawn to the total composition sufficient to distribute the aqueous phase
45 uniformly in the oil phase; and at least one polypropylene glycol is formed. Also formed is an oil-based phase containing
at least a material having a refractive index in the range of 1.40 to 1.50; optionally silicone fluids; and an alkoxylated,
alkyl substituted siloxane surface active agent, being a dimethicone copolyol, in an amount sufficient to from a water-
in-oil embodiment in the cosmetic gel composition. The refractive index of the oil-based phase is determined, and, if
necessary, adjusted to be in the range from 1.4026 to 1.4150, and the refractive index of the aqueous-based phase is
50 determined and adjusted (if necessary) to differ from the refractive index of the oil-based phase by less than 0.0005.
The aqueous-based phase is then mixed with the oil-based phase (for example, the aqueous-based phase is slowly
added to the oil-based phase with turbulent agitation), and then additional additives, such as fragrance and color or
other active ingredients, are added with mixing. The resulting emulsion is then passed through, for example, a colloid
mill or other high shear emulsifier so as to provide a viscous gel, the gel then being transferred to a suitable applicator
55 or container for use by the consumer. According to the present invention the aqueous based phase includes polypro-
pylene glycol, such as tripropylene glycol, providing advantages in the final product as discussed previously.
[0040] The compositions according to the present invention are used as conventional cosmetic gel compositions are
used. For example, where the composition according to the present invention is a clear antiperspirant soft gel compo-

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 EP 0 845 977 B1

sition, packaged in a dispensing container having a top surface with slots or pores, the gel is extruded from the dis-
pensing container through the slots or pores and applied to the skin (for example, in axillary regions of the human
body) by rubbing the soft gel material extruded through the top surface of the container on the skin in the axillary region.
[0041] As a further aspect of the present invention, the dispensing container is a clear container, so as to exhibit the
5 clarity of the composition of the present invention.
[0042] Accordingly, by the present invention, a clear cosmetic gel composition (for example, a clear antiperspirant
gel composition, such as a clear antiperspirant soft gel composition) can be provided, having increased amounts of
cosmetically active ingredients (such as antiperspirant active material) and having other high refractive index beneficial
materials in the composition while maintaining clarity of the composition. The composition is easy to manufacture. The
10 composition has improved tack, a cool sensation, a silky feel and imparts no white residue on dry down compared to
commercially available products. Moreover, compositions of the present invention incorporating a polypropylene glycol
component (especially tripropylene glycol) have improved mildness (have reduced skin irritation potential) as compared
to commercially available products, and have improved cosmetic properties (including reduced tackiness) and reduced
white residue upon application.
15 [0043] Further, the invention is directed to the uses as claimed in claims 33, 34, 36 and 37.

Best Mode for Carrying Out the Invention

[0044] While the invention will be described in connection with specific and preferred embodiments, it will be under-
20 stood that it is not intended to limit the invention to those embodiments. To the contrary, it is intended to cover all
alterations, modifications and equivalents as may be included within the spirit and scope of the invention as defined
by the appended claims.
[0045] Throughout the present disclosure, the present invention is described primarily in connection with a clear soft
gel antiperspirant composition. However, the present invention is not limited to soft gel compositions or to antiperspirant
25 compositions. For example, compositions according to the present invention can be clear deodorant compositions.
Moreover, depending on additional or other active ingredients included in the composition, the composition can also
be an emollient composition, an analgesic (methyl salicylate) composition, a sunscreen composition, etc. Various active
materials incorporated in cosmetic compositions are disclosed in US-A-4,322,400 which document is incorporated
herein for these active materials.
30 [0046] Throughout the present specification, "active antiperspirant" and "active deodorant" materials are discussed.
Both types of materials contribute to reduction of body (e.g., axillary) malodor. By reduction of body malodor, we mean
that, generally, there is less body malodor after application of a composition to the person's skin as compared to the
person's body malodor without application of the composition. Such reduction can be due to a masking of the malodor,
absorption and/or chemical reaction of the malodorous material, reduction of levels of the bacteria producing the mal-
35 odorous material, e.g., from perspiration, reduction of perspiration, etc. The antiperspirant active materials, when uti-
lized in an antiperspirant effective amount in the composition, act to reduce body malodor by reducing production of
perspiration; however, these antiperspirant active materials can also have a deodorant function, e.g., as an antimicrobial
agent. The deodorant active materials do not substantially reduce the production of perspiration, but reduce malodor
in other ways, e.g., as fragrances masking the malodor or reducing the malodor intensity, as odor absorbents, as
40 antimicrobial agents, as agents chemically reacted with malodorous materials, etc.
[0047] Throughout the present specification, where compositions are described as including or comprising specific
components or materials, it is contemplated by the inventors that the compositions of the present invention also consist
essentially of, or consist of, the recited components or materials. Accordingly, throughout the present disclosure any
described composition of the present invention can consist essentially of, or consist of, the recited components or
45 materials.
[0048] A desired feature of the present invention is that a clear, or transparent, cosmetic gel composition (e.g., clear
or transparent deodorant or antiperspirant gel composition) can be provided. The term clear or transparent (that is
clarity), according to the present invention, is intended to connote its usual dictionary definition; thus, a clear, e.g.,
cosmetic gel composition of the present invention allows ready viewing of objects behind it. By contrast, a translucent
50 composition allows light to pass through, but causes the light to be so scattered that it will be impossible to see clearly
objects behind the translucent composition. Optical clarity of compositions of the present invention can be measured
using a turbidimeter, and desirably is better than 50 NTU measured at room temperature (20°-25°C).
[0049] The present invention contemplates a clear cosmetic gel composition which is a water-in-oil emulsion. The
aqueous phase of this emulsion contains water and at least one cosmetically active ingredient, with the cosmetically
55 active ingredient being in the composition in an amount so as to have a cosmetic effect. The oil phase of the emulsion
includes a high refractive index material (a material having a refractive index in the range of 1.40-1.50), and desirably
also includes silicone fluids, and preferably contains both volatile and non-volatile silicone fluids. The compositions
according to the present invention also include at least one coupling agent to bring the aqueous phase and the oil

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phase into a homogeneous composition, and an alkoxylated, alkyl substituted siloxane surface active agent to provide
a water-in-oil emulsion. According to this aspect of the present invention, the composition has a refractive index in a
range from about 1.4026 to 1.4150. This range for the refractive index is higher than the maximum of the range de-
scribed in WO 92/05767. By utilizing a higher refractive index, in a range as disclosed in the present application, clarity
5 of the composition can be maintained, while increased amounts of cosmetic active ingredient (e.g., antiperspirant active
ingredient such as an antiperspirant aluminum-containing salt) can be incorporated in the composition; and high re-
fractive index materials providing advantageous benefits to the composition can be incorporated in the aqueous and
oil phases of the composition.
[0050] The material, incorporated in the oil phase, which has the high refractive index, desirably is an emollient, and
10 preferably has a refractive index in the range of 1.43 to 1.47, most preferably 1.45 to 1.47.
[0051] Desirably, refractive indices of the mixture of aqueous phase and at least one coupling agent, on the one
hand, and the mixture of the oil phase and alkoxylated, alkyl substituted siloxane surface active agent, on the other,
match each other to within 0.0005; that is, a difference between (1) the refractive index of the mixture of aqueous phase
and coupling agents and (2) the refractive index of the mixture of oil phase and alkoxylated, alkyl substituted siloxane
15 surface active agent, is less than 0.0005.
[0052] An optically clear cosmetic (e.g., antiperspirant or deodorant) gel composition that is visually clear, and, like
glass, allows for the viewing of the objects behind it, is achieved. In particular, a composition having an optical clarity
better than 50 NTU at room temperature (20°-25°C), preferably having a turbidity measurement less than 30 NTU,
more preferably less than 20 NTU, can be achieved.
20 [0053] Moreover, the clear cosmetic gel composition of the present invention, which is in the form of a macro-emulsion
as contrasted to a micro-emulsion, does not need to contain wax or gelling agents such as soaps, cellulosic materials
or algenites. Furthermore, the composition according to the present invention does not require polydimethylcyclosi-
loxane, although the present compositions may contain this material.
[0054] The gel emulsions according to the present invention are stable and optically clear, are cosmetically elegant,
25 and are capable of being delivered from a suitable applicator package. They are easily applied to the skin and have a
smooth, silky feel and a cool sensation, yet are fast-drying and non-tacky. These compositions of the present invention
may be prepared by a batch process, or a continuous or semi-continuous process, and the processes yield compositions
which are stable, highly efficacious and possess excellent aesthetic qualities.
[0055] Where the composition is an antiperspirant gel composition, any of the known antiperspirant active materials
30 can be utilized in the composition of the present invention. Suitable materials which may be mentioned by way of
example include aluminum chlorhydrate, aluminum chloride, aluminum sesquichlorohydrate, aluminum-zirconium hy-
droxychlorides, complexes or adducts of the above-mentioned active ingredients with glycol, such as propylene glycol
(for example, "Rehydrol" II from Reheis Chemical Co.), and combinations thereof. Known aluminum-zirconium salts
in combination with neutral amino acids, such as glycine (e.g., aluminum-zirconium tetrachlorohydrex Gly) can also
35 be used. Generally, any of the Category I active antiperspirant ingredients, listed in the Food and Drug Administration's
Monograph on Antiperspirant Drug Products for overall-the-counter human use (October 10, 1973) can be used. In
addition, any new ingredient, not listed in the Monograph, such as aluminum nitratohydrate and its combination with
zirconyl hydroxychlorides and nitrates, or aluminum-stannous chlorohydrates, can be incorporated as an antiperspirant
active ingredient in antiperspirant compositions according to the present invention.
40 [0056] Antiperspirant active materials can be, but are not limited to, the following:

Antiperspirant Actives

[0057]
45
Astringent salt of aluminum
Astringent salt of zirconium
Aluminum bromohydrate
Aluminum chlorohydrate
50 Aluminum dichlorohydrate
Aluminum sesquichlorohydrate
Aluminum chlorohydrex PG
Aluminum dichlorohydrex PG
Aluminum sesquichlorohydrex PG
55 Aluminum chlorohydrex PEG
Aluminum dichlorohydrex PEG
Aluminum sesquichlorohydrex PEG
Aluminum chloride

7
 EP 0 845 977 B1

Aluminum sulfate
Aluminum zirconium chlorohydrate
Aluminum zirconium trichlorohydrate
Aluminum zirconium tetrachlorohydrate
5 Aluminum zirconium pentachlorohydrate
Aluminum zirconium octachlorohydrate
Aluminum zirconium trichlorohydrex Gly
Aluminum zirconium tetrachlorohydrex Gly
Aluminum zirconium pentachlorohydrex Gly
10 Aluminum zirconium octachlorohydrex Gly
Buffered aluminum sulfate
Potassium alum
Sodium aluminum chlorohydroxy lactate

15 [0058] The preferred antiperspirant materials include Rezal 36G, aluminum zirconium tetrachlorohydrate or alumi-
num chlorhydrate.
[0059] The amount of active component that can be used will vary with the particular active ingredient incorporated.
As a general rule, an antiperspirant product should contain an active antiperspirant material in an amount anywhere
from 10% to 35% by weight, of the total weight of the composition, more preferably from 20% to 30% by weight, of the
20 total weight of the composition. The active antiperspirant material utilized in the compositions of the present invention
can be pre-dissolved in water or in another solvent (for example, in propylene glycol), or can be in powdered form, and
may be buffered or unbuffered. Preferably, the antiperspirant materials are present in solution in a solvent therefor.
[0060] Where a deodorant active material is utilized, any deodorant active material which can be dissolved in the
aqueous phase can be utilized. Illustratively, the deodorant active material can be 2, 4, 4'-trichloro-2'-hydroxy diphenyl
25 ether (triclosan), and/or benzethonium chloride. Where the deodorant ingredient is used in place of the antiperspirant
active ingredient, a deodorant gel composition (rather than an antiperspirant gel composition) would be provided.
[0061] Amounts of cosmetically active ingredients incorporated are those sufficient to have a cosmetic effect. For
example, where a deodorant active ingredient such as triclosan is incorporated, amounts thereof as conventionally
used in the art can be incorporated in the composition according to the present invention.
30 [0062] The aqueous phase includes one or a combination of various polar species, and includes at least water (re-
fractive index of 1.3333). Other polar species include polyhydric alcohols and derivatives thereof (e.g., esters and
ethers thereof). Illustratively, water can be included in the composition in an amount in the range of 20% to 70% by
weight, of the total weight of the composition.
[0063] At least one coupling agent is included in the composition of the present invention. Such coupling agent is
35 illustratively (but not limited to) the following:

Ethyl alcohol
2-ethylhexanol
Ethylene carbonate
40 N-methylglucamine
Linear ethoxylated polymer of methanol
Ethylene glycol monoethyl ether
Diethylene glycol monoethyl ether
Propoxylated oleyl alcohol
45 Butyl stearate
Butyl myristate
Isopropyl alcohol
SD-40 alcohol
Mineral Spirits
50 PPG (2-8) myristyl ether
PPG ( 2-8) lauryl ether
Dipropylene glycol
Sorbitol
PPG (2-10) cetyl ether
55 PEG-6 diisopropyl adipate
Methoxy PEG-22 dodecyl-glycol copolymer
PEG-30 Glyceryl monoacetate sorbitol
PEG-3 oleyl ether phosphate

8
 EP 0 845 977 B1

PEG-(2-5) oleyl ether

PPG-(2-5) lanolate
PPG-(2-8) isostearate
Propylene glycol (2) methyl ether
5 PPG-(2-3) methyl ether
PPG-14 butyl ether
Ethoxylated (2-20 moles) glucose
Propoxylated (2-20 moles) glucose
PPG-15 Stearyl ether
10 PPG-(5-20) methyl glucose ether
Isoprene glycol
Propylene carbonate
Glycerine

15 [0064] This coupling agent acts to stabilize the emulsion and also acts as a clarifying agent. Moreover, various of
these coupling agents, such as SD-40 alcohol, aid in drying and has a cooling effect, providing advantageous aesthetic
properties for the composition.
[0065] The coupling agent is preferably a low molecular weight alcohol such as, but not limited to, an alcohol having
from 2 to 10 carbon atoms, preferably from 2 to 4 carbon atoms; or a glycol such as, but not limited to, propylene glycol,
20 ethylene glycol, isoprene glycol and dipropylene glycol; glycerine, sorbitol and/or propylene carbonate. The coupling
agent can be one compound or a mixture of compounds.
[0066] Illustratively, the coupling agent is present in an amount of from 10% to 30% by weight, preferably from 14%
to 25% by weight, of the total weight of the composition.
[0067] The oil phase according to the present invention is, desirably, a silicone oil phase, so as to provide a water-
25 in-silicone oil emulsion. The total of oil phase and siloxane surface active agent preferably makes up from 8% to 30%
by weight, of the total weight of the composition. This surface active agent is an emulsifier which, when properly mixed
with the aqueous phase components, oil phase components and coupling agents, yields a water-in-oil emulsion. The
oil phase is desirably a blend of liquids.
[0068] The oil phase can include, illustratively, a volatile silicone fluid such as cyclomethicone and a non-volatile
30 silicone fluid such as dimethicone; however, the composition of the present invention need not include both the volatile
and non-volatile silicone fluids. Where the composition includes the volatile silicone, it is preferred that such volatile
silicone be a polydimethylcyclosiloxane, present in an amount up to 18% by weight, of the total weight of the compo-
sition, preferably from 4% to 12% by weight, of the total weight of the composition. Preferred polydimethylcyclosiloxanes
are those named cyclomethicones, exemplified by the formula ((CH3)2SiO)x where x is a number from 4 to 6. Preferred
35 cyclosiloxanes are cctamethylcyclotetrasiloxane (x=4), decamethylcyclopentasiloxane (x=5) and blends of tetramer
and pentamer cyclomethicones. Commercial cyclosiloxanes which can be utilized as part of the composition of the
present invention include, illustratively, Dow Corning 244 fluid, Dow Corning 245 fluid, Dow Corning 344 fluid and Dow
Corning 345 fluid (from Dow Corning Corp.).
[0069] The oil phase preferably is a mixture of a volatile silicone fluid (such as cyclomethicone), a non-volatile silicone
40 fluid (such as dimethicone), and a high refractive index compatible emollient such as phenyl trimethicone. This high
refractive index emollient has a higher refractive index than that of the silicone fluids (volatile silicone fluid and/or non-
volatile silicone fluid) of the oil phase.
[0070] The alkoxylated, alkyl substituted siloxane surface active agent is preferably, but not limited to, a dimethicone
copolyol. An illustrative alkoxylated silicone-containing surfactant utilizable according to the present invention is cetyl
45 dimethicone copolyol, referred to in US-A-5,162,378. Illustratively, the alkoxylated, alkyl substituted siloxane surface
active agent is included in t.he composition in an amount of 0.2% to 2% by weight, of the total weight of the composition.
[0071] A specific cyclomethicone-dimethicone copolyol fluid which can be utilized to provide the alkoxylated silicone
containing surface active agent is a mixture of cyclomethicone and dimethicone copolyol designated as DC3225C from
Dow Corning Corp. This is a polyether substituted silicone of cyclomethicone and dimethicone copolyol (refractive
50 index (RI) = 1.3994). This DC3225C, which is an emulsifying agent, is useful for preparing stable water-in-oil emulsions
where a silicone makes up a large portion of the oil phase, and is a dispersion of a silicone surfactant (dimethicone
copolyol) (10% by wt.) in cyclomethicone (Dow Corning 344 Fluid) (90% by wt.).
[0072] The mixture of cyclomethicone and dimethicone copolyol fluid is present in the composition, illustratively, in
an amount of from 4% to 20% by weight, of the total weight of the composition.
55 [0073] Various materials incorporated in the water-based phase and in the oil-based phase, and their refractive
indices (as measured using the Bausch and Lomb Abbe 3L Refractometer), are set forth in the following:

9
 EP 0 845 977 B1

Water-based phase

[0074]

5 Ingredient RI at
21°C
Al-Zr Tetrachlorohydrex GLY (Rexal 36G (cone) 46%) 1.4185
SD40 Alcohol 1.3644
10 PPG-10 Butanediol 1.4510
Propylene Glycol 1.4334
1,3-Butylene Glycol 1.4404
Dipropylene Glycol 1.4415
Propylene Carbonate 1.4216
15
Sorbitol (70%) 1.4605
Isoprene Glycol 1.4422

Tween 80 1.4725
20 Carbowax PEG 200 1.4589
Carbowax PEG 300 1.4650
Carbowax PEG 400 1.4671
Tween 20 1.4705
Water (Deionized) 1.3336
25 Glycerine 1.4743

Oil-based phase

[0075]
30

Ingredient RI at 21°C
Dimethicone (DC 200 (50cs)) 1.4049
Phenyl Trimethicone (DC 556) 1.4614
35 Polyisobutylene (Panalane L-14E) 1.4592
Diisopropyl adipate (Dermol DIA) 1.4248
Polydecene (Silkflo 362NF) 1.4448
Polydecene (Silkflo 364NF) 1.4554
40
Polydecene (Silkflo 366NF) 1.4595
Diisopropyl Sebacate (Pelemol DIPS) 1.4337
Octyl Isononanoate (Dermol 89) 1.4366
Isostearyl Stearate (Estalon ISS) 1.4565
Dermol G-76 1.4988
45 DC Q2-5220 1.4536
DC 3225C 1.3994

[0076] The composition according to the present invention can include additional cosmetically active ingredients
such as emollients, humectants, antiseptics, antioxidants, chelating agents, ultraviolet absorbers, colorants, fragrances
50
and preservatives, as known in the art, which ingredients include, but are not limited to, the following:

Emollients
Stearyl alcohol Stearic acid
55 Glyceryl monoricinoleate Isobutyl palmitate
Glyceryl monostearate Isocetyl stearate
Sulphated tallow Oleyl alcohol

10
 EP 0 845 977 B1

(continued)

Emollients
Propylene glycol Isopropyl laurate
5 Mink oil Sorbitan Stearate
Cetyl alcohol Hydrogenated Castor
Oil
Stearyl stearate Hydrogenated soy
10
glycerides
Isopropyl isostearate Hexyl laurate
Dimethyl brassylate Decyl oleate
Diisopropyl adipate
n-dibutyl sebacate
15 Diisopropyl sebacate
2-ethyl hexyl palmitate
Isononyl isononanoate
Isodecyl isononanoate
Isotridecyl isononanoate
20
2-ethyl hexyl palmitate
2-ethyl hexyl stearate
D-(2-ethyl hexyl) adipate)
Di-(2-ethyl hexyl) succinate
25 Isopropyl myristate
Isopropyl palmitate
Isopropyl stearate
Octacosanol
Butyl stearate
30
Glyceryl monostearate
Polyethylene glycols
Oleic acid
Triethylene glycol
35 Lanolin
Triethylene glycol
Castor Oil
Acetylated lanolin alcohols
Acetylated lanolin
40
Petrolatum
Isopropyl ester of lanolin
fatty acids
Mineral oils
45 Butyl myristate
Isostearic acid
Palmitic acid
PEG-23 oleyl ether
Olelyl Oleate
50
Isopropyl linoleate
Cetyl lactate
Lauryl lactate
Myristyl lactate
55 Quaternised hydroxy alkyl
aminogluconate
Vegetable Oils

11
 EP 0 845 977 B1

(continued)

Emollients
Isodecyl oleate
5 Isostearyl neopentanoate
Myristyl myristate
Oleyl ethoxy myristate
Diglycol stearate
10
Ethylene glycol monostearate
Myristyl stearate
Isopropyl lanolate
Paraffin waxes
Glycyrrhizic acid
15 Hydrocyethyl stearate amide

Humectants
20 Urea Propylene glycol
Glycerin Butylene glycol
Sorbitol Ethyl hexanediol
Sodium 2-pyrrolidone-5-carboxylate C1-10 polyethylene glycols
25 Hyaluronic acid
Soluble collagen Lactic acid
Dibutyl phthalate Sodium pyrrolidone carboxylate
Gelatin Sodium lactate
Polyglycerogen Orotic acid
30

Antiseptics/Preservatives/Antioxidants/ Chelating Agents

Cetyl pyridinium chloride
Tribromosalicylanilide
35
Benzalkonium chloride
Dehydroacetic acid
Methyl paraben
Propyl paraben
40 Sodium dehydroacetate
Quaternium-15
EDTA Benzyl alcohol
Chlorobutanol
Dichlorobenzyl alcohol
45
Phenethyl alcohol

Antiseptics/Preservatives/Antioxidants/Chelating Agents cont.

50 Phenoxyethanol 5-bromo-5-nitro-1,3-dioxane
Propylene glycol Glutaral
Chloroacetamide Tocopherol
Imidazolidinyl urea Zinc pyrithone
Butyl paraben Sodium borate
55
Butylated Hydroxy Anisol Boric acid
Ethyl paraben Isobutyl paraben 2-(hydroxymethylamine)-ethanol

12
 EP 0 845 977 B1

(continued)

Antiseptics/Preservatives/Antioxidants/Chelating Agents cont.

5-chloro-2-methyl-4-isothiazolin-3-one Paraformaldehyde Trimerosol Dodecyl gallate
5 2-methyl-4-isothiazol-3-one formaldehyde Hydroquinone Phenol
Butylated Hydroxy Toluene Sodium pyritione
DMDM hydantoin Stearalkonium chloride
2-bromo-2-nitropropane-1,3-diol
10
Sorbic acid
Citric acid
Triclosan
Diazolidinyl urea
Benzoic acid
15 Propyl gallate
Sodium benzoate
Potassium sorbate
Chloroxylenol
20 Tetrapotassium pyrophosphate
Benzoxiquine
Chlorobutanol
Quaternium-11
U.V. absorber-1
25
Disodium phosphate
Trisodium HEDTA
Benzethonium chloride
Sodium methyl paraben
30 DMHF
MDM hydantoin
O-phenylphenol
Chlorhexidine digluconate
Myristalkonium chloride
35
Ascorbylpalmitate
Isopropyl paraben

Quaternium-15
40 Benzylparaben
Phenyethyl alcohol
Phosphoric acid
Sodium O-phenyl phenate
Chlorhexidine dihydrochloride
45 Phenoxyisopropanol
Resorcinol
Dichlorophen, sodium salt
T-butyl hydroquinone
50
Dichlorophen
Methylbenzethonium chloride
Chlroacetamide
Phenylmercuric acetate
Ascorbic acid
55 Benzyl benzoate
Hydantoin
Sodium sulfite

13
 EP 0 845 977 B1

(continued)

Antiseptics/Preservatives/Antioxidants/Chelating Agents cont.

Sodium bisulfite
5 Iodine

U.V. Absorbers
10 2-hydroxy-4 ethylhexylsalicylate
methoxybenzophenone Menthyl anthranilate
Octyl dimethyl
p-aminobenzoic acid p-dimethyl
aminobenzoate
15
Digalloyl trioleate
2,2-dihydroxy-4-methoxy
benzophenone
Ethyl 4-[bis(hydroxypropyl)]
20 aminobenzoate
2-ethylhexyl 2-cyano-3,3-
diphenylacrylate
Ethyl hexyl p-methoxy
cinnamate2-
25
Ethyl 4(bis(hydroxypropyl))
aminobenzoate
2-phenylbenzimidazole-5-
sulfonic acid
30 Benzophenone-8
Benzophenone-6
Benzophenone-2
Benzophenone-1
Amyl dimethyl PABA
35
Benzophenone-4
Benzophenone-9

[0077] According to another aspect of the present invention, the aqueous phase further includes at least one poly-
40 propylene glycol, preferably tripropylene glycol. By including, e.g., tripropylene glycol in the composition, illustratively,
in an amount in the range of 1% to 20% by weight, of the total weight of the composition, a clear cosmetic (e.g.,
antiperspirant) gel composition can be achieved, having desirable cosmetic properties such as reduced tack and re-
duced whitening.
[0078] While not being held to any theory, it is also thought that use of the glycol, especially a relatively high molecular
45 weight glycol, e.g., tripropylene glycol, may reduce irritation potential by preventing other irritating agents from perme-
ating into the skin, by preventing mechanical chafing of the skin through extended lubrication of the aluminum salt
active particles on the skin surface, and, where appropriate, by avoiding any irritation by propylene glycol.
[0079] According to this aspect of the present invention, the aqueous phase can include a mixture of polypropylene
glycol (e.g., tripropylene glycol) and propylene glycol. Where the composition includes a mixture of both tripropylene
50 glycol and propylene glycol, the mixture illustratively can be included in the aqueous phase in an amount in the range
of 1%-25% by weight, of the total weight of the composition.
[0080] While not limiting, in preferred embodiments the mixture of oil phase and alkoxylated, alkyl substituted siloxane
surface active agent comprises from 10% to 30% by weight, of the total weight of the composition, and the combination
of aqueous phase and coupling agents make up from 70% to 90% by weight, of the total weight of the composition.
55 [0081] In manufacturing the composition, and to provide an optically clear product (for example, an optically clear
antiperspirant product), refractive indices of a mixture of oil phase and alkoxylated, alkyl substituted silicone surface
active agent, on the one hand, and a mixture of the aqueous phase and the at least one coupling agent, on the other,
are measured using a suitable refractometer such as a Bausch and Lomb Abbe 3L Refractometer, and the refractive

14
 EP 0 845 977 B1

index of one of these mixtures is adjusted as necessary in order to have a refractive index of one mixture that is within
0.0005 of the other mixture. In particular, in connection with antiperspirant compositions according to the present in-
vention, the oil phase and alkoxylated, alkyl substituted silicone surface active agent are mixed and the refractive index
of the mixture is optically measured. The aqueous phase is formulated using, inter alia, the active ingredient and water,
5 and the coupling agent is mixed therewith and the refractive index of this mixture of aqueous phase and coupling agent
is optically measured. If the two mixtures do not match within 0.0005, refractive indices of either mixture can be adjusted.
Preferably, the mixture including the aqueous phase has its refractive index adjusted by adding a coupling agent or
water to change the refractive index so that it matches the refractive index of the mixture of oil phase and surface active
agent, to at least 0.0005, at 21°C. Adding the coupling agent to the aqueous phase increases the refractive index of
10 the mixture, while adding water to the aqueous phase reduces the refractive index of the mixture. Following adjustment,
the mixtures are again optically measured to verify sufficient matching of the refractive indices. The mixture of the
aqueous phase and coupling agent is then slowly added to the mixture of the oil phase and alkoxylated, alkyl substituted
siloxane surface active agent, with turbulent agitation; optionally, fragrance can then be added, and the mixture sheared
(e.g., by passing the resulting emulsion through a colloid mill or other suitable high shear emulsifier) to form a stable
15 water-in-oil emulsion with desired viscosities, illustratively, in excess of 40,000 mPa.s (40,000 cps) at room temperature
(20°-25°C), preferably, between 75,000 and 350,000 mPa.s (cps), more preferably between 120,000 and 325,000
mPa.s (cps), most preferably between 200,000 and 325,000 mPa.s (cps).
[0082] After formation of the composition having the desired viscosity, the composition can then be packaged into
conventional packages, using conventional techniques. For example, the gel can be introduced into a dispensing pack-
20 age (for example, a package having a top surface with slots or pores), as conventionally done in the art. Desirably, the
dispensing package is a clear package, so as to exhibit the clear composition to the purchasing consumer.
[0083] Thereafter, the product can be dispensed from this dispensing package, by extruding the gel from the dis-
pensing package onto the top surface, through the pores or slots, and then rubbing the exposed gel on the skin, (for
example, on skin in the axillary regions), so as to deposit the active material (for example, antiperspirant active material)
25 on the skin. This provides good deposition of the antiperspirant active material, as well as other active materials, on
the skin.
[0084] In the following, specific examples of compositions within the scope of the various aspects of the present
invention are set forth. These specific examples are illustrative of the present invention, and are not limiting. In the
following examples, as well as throughout the present specification, where appropriate the names utilized are the CTFA
30 (Cosmetics, Toiletry and Fragrance Association, Inc.) names, as set forth in the CTFA International Cosmetic Ingredient
Dictionary (4th Ed. 1991), the contents of which dictionary are incorporated herein by reference in their entirety.
Amounts of each of the ingredients is in percent by weight, of the total weight of the composition.

35

40

45

50

55

15
 EP 0 845 977 B1

10

15

20

25

30

35

40

45

50

55

16
 EP 0 845 977 B1

10

15

20

25

30

35

40

45

50
[0085] In the foregoing Examples 10-12, the refractive index of each composition without the fragrance, was 1.4075.
[0086] Thus, according to the present invention, a clear cosmetic gel composition, which can be a soft gel, containing
increased amounts of the cosmetically active ingredient (e.g. increased amounts of the antiperspirant active ingredient,
where the composition is an antiperspirant gel composition), and also containing in both the oil phase and the aqueous
55 phase high-refractive index materials providing cosmetic benefits, can be achieved, while maintaining clarity of the
composition. This composition can be extruded through pores or slots of a conventional soft solid or soft gel dispensing
container. The compositions are stable, even in the presence of conventional antiperspirant active aluminum-containing
salts such as aluminum chlorohydrate or aluminum-zirconium tetrachlorohydrex-GLY. Compositions according to the

17
 EP 0 845 977 B1

present invention can be easily and simply manufactured. Moreover, the composition according to the present invention
has reduced whitening and leaves a decreased residue after application, and has reduced tack. In addition, composi-
tions according to the present invention have reduced skin irritation potential as compared to comparable commercial
products.
5
Industrial Applicability

[0087] As is clear from the foregoing, the composition of the present invention has applicability as a cosmetic com-
position, having various uses depending upon the active cosmetic ingredient incorporated therein. For example, the
10 composition of the present invention has applicability as an antiperspirant composition, for application to axillary regions
of the human body to at least reduce perspiration therefrom, where an antiperspirant active ingredient is incorporated
in the composition. As a further illustration, the composition has applicability as a deodorant composition for application
to axillary regions of the human body to reduce body malodor without reducing flow of perspiration, where the compo-
sition includes a deodorant active ingredient which is not an antiperspirant (e.g., an antimicrobial agent such as Tri-
15 closan, a fragrance, etc.). However, the present invention is not limited to these specific uses, and can have other
uses, depending on the cosmetically active ingredient incorporated therein, and can be applied, e.g., to other parts of
a body. The present invention also has applicability in forming these compositions.
[0088] While we have shown and described several embodiments in accordance with the present invention, it is
understood that the same is not limited thereto, but is susceptible to numerous changes and modifications as known
20 to one having ordinary skill in the art, and we therefore do not wish to be limited to the details shown and described
herein, but intend to cover all such modifications as are encompassed by the scope of the appended claims.

Claims
25
1. A clear and mild cosmetic gel composition comprising:

(a) an aqueous phase containing (i) water; (ii) at least one cosmetically active ingredient in an amount sufficient
to have a cosmetic effect; and (iii) a glycol;
30 (b) an oil phase containing a material having a refractive index in the range of 1.40 to 1.50;
(c) 10-30% of at least one coupling agent such that the aqueous phase is uniformly distributed in the oil phase;
(d) an alkoxylated, alkyl substituted siloxane surface active agent in an amount so as to form a water-in-oil
emulsion;

35 wherein said cosmetic gel composition is a water-in-oil emulsion and wherein the cosmetic gel composition
has a refractive index in a range of 1.4026 - 1.4150, characterized in that the glycol is at least one polypropylene
glycol and the alkoxylated, alkyl substituted siloxane surface active agent is a dimethicone copolyol.

2. A clear and mild cosmetic gel composition according to Claim 1 wherein the refractive index of cosmetic gel com-
40 position is in a range of 1.4050 to 1.4085.

3. A clear and mild cosmetic gel composition according to Claim 2 wherein the refractive index of the cosmetic gel
composition is in a range of 1.4060 to 1.4080.

45 4. A clear and mild cosmetic gel composition according to Claim 1 wherein each of (a) a mixture of the aqueous
phase and the coupling agent; and (b) a mixture of the oil phase and the alkoxylated, alkyl substituted siloxane
surface active agent, has a refractive index and with a difference between the refractive indices of (a) and (b) of
less than 0.0005.

50 5. A clear and mild cosmetic gel composition according to Claim 4 having an optical clarity of less than 50 NTU.

6. A clear and mild cosmetic gel composition according to Claim 1 wherein the cosmetically active ingredient is an
antiperspirant active ingredient.

55 7. A clear and mild cosmetic gel composition according to Claim 6 wherein the antiperspirant active agent is added
to the composition in an amount sufficient to reduce perspiration flow when the composition is applied to human
axillary skin and whereby a clear and mild antiperspirant gel composition is formed.

18
 EP 0 845 977 B1

8. A clear and mild cosmetic gel composition according to Claim 7 wherein the antiperspirant active agent is added
to the composition in an amount of 10% to 35% by weight based on the total weight of the composition.

9. A clear and mild cosmetic gel composition according to Claim 8 wherein the at least one coupling agent is added
5 to the composition in an amount of 14% to 25% by weight.

10. A clear and mild cosmetic gel composition according to Claim 9 wherein the alkoxylated. alkyl substituted siloxane
surfactant is included in the composition in an amount of from 0.2% to 2.0% by weight based on the total weight
of the composition.
10
11. A clear and mild cosmetic gel composition according to Claim 10, wherein the alkoxylated, alkyl substituted siloxane
surfactant and the oil phase is added in a combined amount of 8% to 30% by weight based on the total weight of
the composition.

15 12. A clear and mild cosmetic gel composition according to Claim 11 wherein the composition is a soft gel.

13. A clear and mild cosmetic gel composition according to Claim 11 wherein the composition has a viscosity of from
75,000 to 350.000 mPa.s (cps) at a temperature of 20°C - 25 °C.

20 14. A clear and mild cosmetic gel composition according to Claim I I wherein a volatile silicone fluid and a non-volatile
silicone fluid are added to the oil phase and wherein the material having a refractive index of 1.40 to 1.50 is an
emollient.

15. A clear and mild cosmetic gel composition according to Claim 14 wherein the emollient has a higher refractive
25 index than each of the volatile silicone fluid and the non-volatile silicone fluid.

16. A clear and mild cosmetic gel composition according to Claim 1 wherein the aqueous phase and the at least one
coupling agent are added in a combined amount of 70% - 90% by weight based on the total weight of the compo-
sition; and the oil phase and alkoxylated, alkyl substituted silicone surface active agent are added in a combined
30 amount of 10% - 30% by weight based on the total weight of the composition.

17. A clear and mild cosmetic gel composition according to Claim 16 wherein the polypropylene glycol includes tripro-
pylene glycol.

35 18. A clear and mild cosmetic gel composition according to Claim 17 wherein the alkoxylated, alkyl substituted siloxane
surface active agent is cetyl dimethicone copolyol.

19. A packaged antiperspirant gel composition comprising the clear and mild cosmetic gel composition according to
any one of Claims 8-17 in a clear package.
40
20. A clear and mild cosmetic gel composition according to Claim 1 wherein the cosmetically active ingredient includes
at least one deodorant active agent in an amount sufficient to provide a deodorizing effect.

21. A clear and mild cosmetic gel composition according to claim 1 made by combining:
45
(a) water
(b) at least one coupling agent;
(c) at least one polypropylene glycol;
(d) an antiperspirant active ingredient in an amount sufficient to have an antiperspirant effect when applied to
50 human skin;
(e) a non-volatile silicone fluid;
(f) a volatile silicone fluid;
(g) an emollient having a refractive index of 1.40 - 1.50; and
(h) the alkoxylated, alkyl substituted siloxane surface active agent;
55
wherein components (a) -(h) form a water-in-oil emulsion. the emollient is in the oil phase. and the composition
has a refractive index of 1.4026 - 1.4150, and wherein a soft gel is formed.

19
 EP 0 845 977 B1

22. A clear and mild cosmetic gel composition according to Claim 21 wherein the composition is made by combining
in percent by weight based on the total weight of the composition: 8% - 30% in total of components (e), (f), (g) and
(h) of Claim 21 wherein the 8% - 30% includes 0.2 - 2.0% of the alkoxylated. alkyl substituted siloxane surface
active agent and 10% - 30% of at least one coupling agent.
5
23. A clear and mild cosmetic gel composition according to Claim 22 wherein the antiperspirant active ingredient is
included in the composition in an amount of 10% to 35% by weight based on the total weight of the composition.

24. A clear antiperspirant soft gel composition according to Claim 23 wherein the emulsion has an optical clarity less
10 than 50 NTU.

25. A clear and mild cosmetic gel composition according to Claim 21 wherein each of (1) a mixture of components (a)
- (d); and (2) a mixture of components (e) - (h) has a refractive index and with a difference between the refractive
indices of (a) and (b) of less than 0.0005.
15
26. A clear and mild cosmetic gel composition according to Claim 25 wherein the composition has a viscosity of 75,000
- 350,000 mPa.s (cps) at a temperature of 20 °C - 25 °C.

27. A clear and mild cosmetic gel composition according to Claim 17 wherein the aqueous phase further includes
20 propylene glycol.

28. A clear and mild cosmetic gel composition according to Claim 1 wherein the oil phase includes silicone fluids.

29. A method of forming the clear and mild cosmetic gel composition of claim 1 comprising the steps of
25
a) forming an aqueous-based phase of (i) water; (ii) at least one cosmetically active ingredient in an amount
sufficient to have a cosmetic effect; (iii) at least one coupling agent in an amount of 10-30%, drawn to the total
composition, sufficient to distribute the aqueous phase uniformly in the oil phase; and (iv) at least one poly-
propylene glycol;
30 (b) forming an oil-based phase containing a material having a refractive index in the range of 1.40 to 1.50;
optionally silicone fluids; and an alkoxylated, alkyl substituted siloxane surface active agent, being a dime-
thicone copolyol, in an amount sufficient to form a water-in-oil emulsion in the cosmetic gel composition;

wherein each of the aqueous-based phase and the oil-based phase has a refractive index which is determined
35 and optionally adjusted to a difference between the refractive indices of less than 0.0005; mixing the aqueous-
based phase with the oil-based phase and wherein said cosmetic gel composition is a water-in-oil emulsion and
wherein the cosmetic gel composition has a refractive index in a range of 1.4026 - 1.4150.

30. The method according to claim 29 wherein the at least one polypropylene glycol includes tripropylene glycol.
40
31. The method according to claim 29 wherein the silicone fluids are present and include a volatile silicone fluid and
a non-volatile fluid, and wherein the material having a refractive index in the range of 1.40-1.50 is an emollient
having a higher refractive index than that of the volatile silicone fluid and the non-volatile silicone fluid.

45 32. The method according to claim 29 wherein after the mixing the resulting mixture is transferred to a dispensing
container for use by a consumer.

33. Non-therapeutic use of compositions as defined in claim 1, for the reduction of skin irritation potential.

50 34. Non-therapeutic use of tripropylene glycol in a clear and mild cosmetic gel composition comprising

a) forming an aqueous-based phase of (i) water; (ii) at least one cosmetically active ingredient in an amount
sufficient to have a cosmetic effect; (iii) at least one polypropylene glycol;
(b) an oil phase containing a material having a refractive index in the range of 1.40 to 1.50;
55 (c) 10-30% of at least one coupling agent such that the aqueous phase is uniformly distributed in the oil phase;
(d) an alkoxylated, alkyl substituted siloxane surface active agent, being a dimethicone copolyol, in an amount
so as to form a water-in-oil emulsion; in the cosmetic gel composition;

20
 EP 0 845 977 B1

wherein said cosmetic gel composition is a water-in-oil emulsion and wherein the cosmetic gel composition has a
refractive index in a range of 1.4026-1.4150 for the reduction of skin irritation potential.

35. Composition according to claim 17, wherein the amount of tripropylene glycol ranges from 1-20%.
5
36. Non-therapeutic use of compositions as defined in claim 1 for the reduction of whitening and leaving decreased
residue after application.

37. Use of a composition as defined in claim 1 for the manufacture of a medicament for reducing skin irritation.
10

Patentansprüche

1. Klare und milde Kosmetikgelzusammensetzung, die:

15
(a) eine wässrige Phase, die (i) Wasser, (ii) mindestens einen kosmetisch wirksamen Bestandteil in einer
Menge, die ausreicht, um einen kosmetischen Effekt zu bewirken, und (iii) ein Glykol enthält,

(b) eine Ölphase, die ein Material mit einem Brechungsindex im Bereich von 1,40 bis 1,50 enthält,
20
(c) 10 bis 30 % mindestens eines Kupplungsmittels, so dass die wässrige Phase gleichförmig in der Ölphase
verteilt ist, und

(d) ein alkoxyliertes alkylsubstituiertes Siloxantensid in einer Menge umfasst, so dass eine Wasser-in-Öl-Emul-
25 sion gebildet wird,

wobei die Kosmetikgelzusammensetzung eine Wasser-in-Öl-Emulsion ist und wobei die Kosmetikgelzusammen-
setzung einen Brechungsindex im Bereich von 1,4026 bis 1,4150 aufweist,
dadurch gekennzeichnet, dass das Glykol mindestens ein Polypropylenglykol ist und das alkoxylierte alkylsub-
30 stituierte Silonxantensid ein Dimethiconcopolyol ist.

2. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, bei der der Brechungsindex der Kosmetikgel-
zusammensetzung im Bereich von 1,4050 bis 1,4085 liegt.

35 3. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 2, bei der der Brechungsindex der Kosmetikgel-
zusammensetzung im Bereich von 1,4060 bis 1,4080 liegt.

4. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, bei der jedes von (a) einer Mischung aus der
wässrigen Phase und dem Kupplungsmittel und (b) einer Mischung aus der Ölphase und dem alkoxylierten al-
40 kylsubstituierten Silonxantensid einen Brechungsindex aufweist, wobei die Differenz zwischen den Brechungsin-
dizes von (a) und (b) kleiner als 0,0005 ist.

5. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 4, die eine optische Klarheit unter 50 NTU besitzt.

45 6. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, bei der der kosmetisch wirksame Bestandteil
ein als Antiperspirant wirksamer Bestandteil ist.

7. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 6, bei der der als Antiperspirant wirksame Be-
standteil der Zusammensetzung in einer Menge zugesetzt worden ist, die ausreicht, um den Schweißfluss zu
50 verringern, wenn die Zusammensetzung auf die menschliche Achselhaut aufgebracht wird, wobei eine klare und
milde Antiperspirantgelzusammensetzung gebildet worden ist.

8. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 7, bei der der als Antiperspirant wirksame Be-
standteil der Zusammensetzung in einer Menge von 10 bis 35 Gew.-%, bezogen auf das Gesamtgewicht der
55 Zusammensetzung, zugesetzt worden ist.

9. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 8, bei der mindestens ein Kupplungsmittel der
Zusammensetzung in einer Menge von 14 bis 25 Gew.-% zugesetzt worden ist.

21
 EP 0 845 977 B1

10. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 9, bei der das alkoxylierte alkylsubstituierte Silo-
xantensid in der Zusammensetzung in einer Menge von 0,2 bis 2,0 Gew.-%, bezogen auf das Gesamtgewicht der
Zusammensetzung, enthalten ist.

5 11. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 10, bei der das alkoxylierte alkylsubstituierte Si-
loxantensid und die Ölphase in einer kombinierten Menge von 8 bis 30 Gew.-%, bezogen auf das Gesamtgewicht
der Zusammensetzung, zugesetzt worden sind.

12. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 11, bei der die Zusammensetzung ein weiches
10 Gel ist.

13. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 11, bei der die Zusammensetzung eine Viskosität
von 75000 bis 350000 mPa·s (cPs) bei einer Temperatur von 20 °C bis 25 °C aufweist.

15 14. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 11, bei der ein flüchtiges Silikonfluid und ein nicht-
flüchtiges Silikonfluid zu der Ölphase gegeben worden sind und bei der das Material mit einem Brechungsindex
von 1,40 bis 1,50 ein Aufweichmittel ist.

15. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 14, bei der das Aufweichmittel einen höheren
20 Brechungsindex als jedes von dem flüchtigen Silikonfluid und dem nichtflüchtigen Silikonfluid aufweist.

16. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, bei der die wässrige Phase und das mindestens
eine Kupplungsmittel in einer kombinierten Menge von 70 bis 90 Gew.-%, bezogen auf das Gesamtgewicht der
Zusammensetzung, zugesetzt worden sind, und die Ölphase und das alkoxylierte alkylsubstituierte Silikontensid
25 in einer kombinierten Menge von 10 bis 30 Gew.-%, bezogen auf das Gesamtgewicht der Zusammensetzung,
zugesetzt worden sind.

17. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 16, bei der das Polypropylenglykol Tripropylen-
glykol einschließt.
30
18. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 17, bei der das alkoxylierte alkylsubstituierte Si-
loxantensid Cetyldimethiconcopolyol ist.

19. Verpackte Antiperspirantgelzusammensetzung, die die klare und milde Kosmetikzusammensetzung gemäß einem
35 der Ansprüche 8 bis 17 in einer klaren Verpackung umfasst.

20. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, bei der der kosmetisch wirksame Bestandteil
mindestens einen Deodorantwirkstoff in einer Menge einschließt, die ausreicht, um einen deodorierenden Effekt
zu liefern.
40
21. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, die durch Konbinieren von

(a) Wasser,
(b) mindestens einem Kupplungsmittel,
45 (c) mindestens einem Polypropylenglykol,
(d) einem als Antiperspirant wirksamen Bestandteil in einer Menge, die ausreicht, einen Antiperspiranteffekt
zu ergeben, wenn sie auf menschliche Haut aufgebracht wird,
(e) einem nichtflüchtigen Silikonfluid,
(f) einem flüchtigen Silikonfluid,
50 (g) einem Aufweichmittel mit einem Brechungsindex von 1,40 bis 1,50, und
(h) dem alkoxylierten alkylsubstituierten Silikontensid hergestellt worden ist,

wobei die Komponenten (a) bis (h) eine Wasser-in-Öl-Emulsion bilden, das Aufweichmittel in der Ölphase vorliegt
und die Zusammensetzung einen Brechungsindex von 1,4026 bis 1,4150 aufweist, wobei ein weiches Gel gebildet
55 worden ist.

22. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 21, bei der die Zusammensetzung durch Kombi-
nieren in Gew.-%, bezogen auf das Gesamtgewicht der Zusammensetzung, von: 8 bis 30 % insgesamt an den

22
 EP 0 845 977 B1

Komponenten (e), (f), (g) und (h) gemäß Anspruch 21, wobei die 8 bis 30% 0,2 bis 2,0 % des alkoxylierten al-
kylsubstituierten Silikontensids einschließen, und 10 bis 30 % mindestens eines Kupplungsmittels gebildet worden
ist.

5 23. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 22, bei der der als Antiperspirant wirksame Be-
standteil in der Zusammensetzung in einer Menge von 10 bis 35 Gew.-%, bezogen auf das Gesamtgewicht der
Zusammensetzung, enthalten ist.

24. Klare Antiperspirantweichgelzusammensetzung nach Anspruch 23, bei der die Emulsion eine optische Klarheit
10 unter 50 NTU aufweist.

25. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 21, bei der jedes von (1) einer Mischung der Kom-
ponenten (a) bis (d) und (2) einer Mischung der Komponenten (e) bis (h) einen Brechungsindex mit einer Differenz
zwischen den Brechungsindizes von (a) und (b) von weniger als 0,0005 aufweist.
15
26. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 25, bei der die Zusammensetzung eine Viskosität
von 75000 bis 350000 mPa·s (cPs) bei einer Temperatur von 20 °C bis 25 °C aufweist.

27. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 17, bei der die wässrige Phase ferner Propylen-
20 glykol enthält.

28. Klare und milde Kosmetikgelzusammensetzung nach Anspruch 1, bei der die Ölphase Silikonfluide enthält.

29. Verfahren zur Herstellung der klaren und milden Kosmetikgelzusammensetzung gemäß Anspruch 1, bei dem
25
(a) eine auf Wasser basierende Phase aus (i) Wasser, (ii) mindestens einem kosmetisch wirksamen Bestand-
teil in einer Menge, die ausreicht, um eine kosmetischen Effekt zu bewirken, (iii) mindestens einem Kupp-
lungsmittel in einer Menge von 10 bis 30 %, bezogen auf das gesamte Zusammensetzung, die ausreicht, um
die wässrige Phase gleichförmig in der Ölphase zu verteilen, und (iv) mindestens ein Polypropylenglykol ge-
30 bildet wird,

(b) eine auf Öl basierende Phase gebildet wird, die ein Material mit einem Brechungsindex im Bereich von
1,40 bis 1,50, gegebenenfalls Silikonfluide, und ein alkoxyliertes alkylsubstituiertes Siloxantensid, das ein
Dimethiconcopolyol ist, in einer Menge enthält, die ausreicht, um eine Wasser-in-Öl-Emulsion in der Kosme-
35 tikgelzusammensetzung zu bilden,

wobei jede von der auf Wasser basierenden Phase und der auf Öl basierenden Phase einen Brechungsindex
aufweist, der bestimmt und optisch auf einen Unterschied zwischen den Brechungsindizes von weniger als 0,0005
eingestellt wird,
40 die auf Wasser basierende Phase mit der auf Öl basierenden Phase gemischt wird,
die Kosmetikgelzusammensetzung eine Wasser-in-Öl-Emulsion ist und
die Kosmetikgelzusammensetzung einen Brechungsindex im Bereich von 1,4026 bis 1,4150 aufweist.

30. Verfahren nach Anspruch 29, bei dem das mindestens eine Polypropylenglykol Tripropylenglykol einschließt.
45
31. Verfahren nach Anspruch 29, bei dem die Silikonfluide vorhanden sind und ein flüchtiges Silikonfluid und ein nicht-
flüchtiges Silikonfluid einschließen, und bei dem das Material mit einem Brechungsindex im Bereich von 1,40 bis
1,50 ein Aufweichmittel mit einem höheren Brechungsindex ist, als derjenige des flüchtigen Silikonfluids und des
nichtflüchtigen Silikonfluids.
50
32. Verfahren nach Anspruch 29, bei dem die resultierende Mischung nach dem Mischen in einen Abgabebehälter
zur Verwendung durch einen Verbraucher überführt wird.

33. Nicht-therapeutische Verwendung von Zusammensetzungen gemäß Anspruch 1 für die Verringerung von Haut-
55 reizungspotential.

34. Nicht-therapeutische Verwendung von Tripropylenglykol in einer klaren und milden Kosmetikgelzusammenset-
zung, die

23
 EP 0 845 977 B1

(a) eine auf Wasser basierende Phase aus (i) Wasser, (ii) mindestens einem kosmetisch wirksamen Bestand-
teil in einer Menge, die ausreicht, um einen kosmetischen Effekt zu bewirken, (iii) mindestens einem Polypro-
pylenglykol,

5 (b) eine Ölphase, die ein Material mit einem Brechungsindex im Bereich von 1,40 bis 1,50 aufweist,

(c) 10 bis 30 % mindestens eines solchen Kupplungsmittels, dass die wässrige Phase gleichförmig in der
Ölphase verteilt wird,

10 (d) ein alkoxyliertes alkylsubstituiertes Siloxantensid, das ein Dimethiconcopolyol ist, in einer solchen Menge,
dass eine Wasser-in-Öl-Emulsion gebildet wird, in der Kosmetikgelzusammensetzung umfasst,

wobei die Kosmetikgelzusammensetzung eine Wasser-in-Öl-Emulsion ist und wobei die Kosmetikgelzusammen-
setzung einen Brechungsindex im Bereich von 1,4026 bis 1,4150 aufweist, für die Verringerung von Hautreizungs-
15 potential.

35. Zusammensetzung nach Anspruch 17, bei der die Menge an Tripropylenglykol von 1 bis 20 % reicht.

36. Nicht-therapeutische Verwendung von Zusammensetzungen gemäß Anspruch 1 zur Verringerung des Weißens
20 und Hinterlassens von weniger Rückstand nach Auftragung.

37. Verwendung einer Zusammensetzung gemäß Anspruch 1 zur Herstellung eines Medikaments zur Verringerung
von Hautreizung.

25
Revendications

1. Composition de gel cosmétique transparente et douce comprenant :

30 a) une phase aqueuse contenant (i) de l'eau; (ii) au moins un ingrédient cosmétiquement actif en quantité
suffisante pour avoir un effet cosmétique; et (iii) un glycol;
b) une phase d'huile contenant un matériau ayant un indice de réfraction dans la plage de 1,40 à 1,50;
c) 10% à 30% d'au moins un agent de couplage tel que la phase aqueuse soit uniformément distribuée dans
la phase d'huile; et
35 d) un agent tensioactif de siloxane alcoxylé substitué par des groupes alkyle en quantité telle que soit formée
une émulsion eau dans l'huile;

dans laquelle ladite composition de gel cosmétique est une émulsion eau dans l'huile et dans laquelle la compo-
sition de gel cosmétique a un indice de réfraction dans la plage de 1,4026 à 1,4150,
40 caractérisée en ce que le glycol est au moins un polypropylèneglycol et l'agent tensioactif de siloxane alcoxylé
substitué par des groupes alkyle est un copolyol de diméthicone.

2. Composition de gel cosmétique transparente et douce selon la revendication 1, dans laquelle l'indice de réfraction
de la composition de gel cosmétique se situe dans la plage de 1,4050 à 1,4085.
45
3. Composition de gel cosmétique transparente et douce selon la revendication 2, dans laquelle l'indice de réfraction
de la composition de gel cosmétique se situe dans la plage de 1,4060 à 1,4080.

4. Composition de gel cosmétique transparente et douce selon la revendication 1, dans laquelle chacun (a) d'un
50 mélange de la phase aqueuse et de l'agent de couplage; et (b) d'un mélange de la phase huileuse et de l'agent
tensioactif de siloxane alcoxylé substitué par des groupes alkyle a un indice de réfraction et la différence entre les
indices de réfraction de (a) et (b) est inférieure à 0,0005.

5. Composition de gel cosmétique transparente et douce selon la revendication 4, ayant une transparence optique
55 inférieure à 50 NTU.

6. Composition de gel cosmétique transparente et douce selon la revendication 1, dans laquelle l'ingrédient cosmé-
tiquement actif est un ingrédient actif antiperspirant.

24
 EP 0 845 977 B1

7. Composition de gel cosmétique transparente et douce selon la revendication 6, dans laquelle l'agent actif anti-
perspirant est ajouté à la composition en quantité suffisante pour réduire le flux de transpiration lorsque la com-
position est appliquée à la peau axillaire humaine et de sorte qu'une composition de gel antiperspirante transpa-
rente et douce soit formée.
5
8. Composition de gel cosmétique transparente et douce selon la revendication 7, dans laquelle l'agent actif anti-
perspirant est ajouté à la composition en quantité de 10% à 35% en poids par rapport au poids total de la com-
position.

10 9. Composition de gel cosmétique transparente et douce selon la revendication 8, dans laquelle le au moins un agent
de couplage est ajouté à la composition en quantité de 14% à 25% en poids.

10. Composition de gel cosmétique transparente et douce selon la revendication 9, dans laquelle l'agent tensioactif
de siloxane alcoxylé substitué par des groupes alkyle est inclus dans la composition en quantité de 0,2% à 2,0%
15 en poids par rapport au poids total de la composition.

11. Composition de gel cosmétique transparente et douce selon la revendication 10, dans laquelle l'agent tensioactif
de siloxane alcoxylé substitué par des groupes alkyle et la phase d'huile sont ajoutés en quantité combinée de
8% à 30% en poids par rapport au poids total dc la composition.
20
12. Composition de gel cosmétique transparente et douce selon la revendication 11, dans laquelle la composition est
un gel doux.

13. Composition de gel cosmétique transparente et douce selon la revendication 11, dans laquelle la composition a
25 une viscosité de 75 000 à 350 000 mPa.s (cps) à une température de 20°C à 25°C.

14. Composition de gel cosmétique transparente et douce selon la revendication 11, dans laquelle un fluide de silicone
volatil et un fluide de silicone non volatil sont ajoutés à la phase d'huile et dans laquelle le matériau ayant un indice
de réfraction de 1,40 à 1,50 est un émollient.
30
15. Composition de gel cosmétique transparente et douce selon la revendication 14, dans laquelle l'émollient a un
indice de réfraction supérieur à celui de chacun du fluide de silicone volatil et du fluide de silicone non volatil.

16. Composition de gel cosmétique transparente et douce selon la revendication 1, dans laquelle la phase aqueuse
35 et le au moins un agent de couplage sont ajoutés en quantité combinée de 70% à 90% en poids par rapport au
poids total de la composition; et la phase d'huile et l'agent tensioactif de silicone alcoxylé substitué par des groupes
alkyle sont ajoutés en quantité combinée de 10% à 30% en poids par rapport au poids total de la composition.

17. Composition de gel cosmétique transparente et douce selon la revendication 16, dans laquelle le polypropylène-
40 glycol comprend le tripropylène glycol.

18. Composition de gel cosmétique transparente et douce selon la revendication 17, dans laquelle l'agent tensioactif
de siloxane alcoxylé substitué par des groupes alkyle est un copolyol de cétyldiméthicone.

45 19. Composition de gel antiperspirante conditionnée comprenant la composition de gel cosmétique transparente et
douce selon l'une quelconque des revendications 8 à 17, dans un conditionnement transparent.

20. Composition de gel cosmétique transparente et douce selon la revendication 1, dans laquelle l'ingrédient cosmé-
tiquement actif comprend au moins un agent actif déodorant en quantité suffisante pour fournir un effet désodo-
50 risant.

21. Composition de gel cosmétique transparente et douce selon la revendication 1 préparée en combinant :

a) de l'eau;
55 b) au moins un agent de couplage;
c) au moins un polypropylèneglycol;
d) un agent actif antiperspirant en quantité suffisante pour avoir un effet antiperspirant lorsqu'il est appliqué
à la peau humaine;

25
 EP 0 845 977 B1

e) un fluide siliconé non volatil;

f) un fluide siliconé volatil;
g) un émollient ayant un indice de réfraction de 1,40 à 1,50; et
h) l'agent tensioactif de siloxane alcoxylé substitué par des groupes alkyle;
5
dans laquelle les composants (a) à (h) forment une émulsion eau dans l'huile, l'émollient est dans la phase d'huile
et la composition a un indice de réfraction de 1,4026 à 1,4150, et dans laquelle un gel doux est formé.

22. Composition de gel cosmétique transparente et douce selon la revendication 21, dans laquelle la composition est
10 préparée en combinant en pourcent en poids par rapport au poids total de la composition 8% à 30% au total de
composants (e), (f), (g), et (h) selon la revendication 21, dans laquelle les 8% à 30% comprennent 0,2% à 2,0%
de l'agent tensioactif de siloxane alcoxylé substitué par des groupes alkyle et 10% à 30% d'au moins un agent de
couplage.

15 23. Composition de gel cosmétique transparente et douce selon la revendication 22, dans laquelle l'ingrédient actif
antiperspirant est inclus dans la composition en quantité de 10% à 35% en poids par rapport au poids total de la
composition.

24. Composition de gel souple antiperspirante transparente selon la revendication 23, dans laquelle l'émulsion a une
20 transparence optique inférieure à 50 NTU.

25. Composition de gel cosmétique transparente et douce selon la revendication 21, dans laquelle chacun (1) d'un
mélange de composants (a) à (d) et (2) d'un mélange de composants (e) à (h) a un indice de réfraction et la
différence entre les indices de réfraction de (a) et (b) est inférieure à 0,0005.
25
26. Composition de gel cosmétique transparente et douce selon la revendication 25, dans laquelle la composition a
une viscosité de 75 000 à 350 000 mPa.s (cps) à une température de 20°C à 25°C.

27. Composition de gel cosmétique transparente et douce selon la revendication 17, dans laquelle la phase aqueuse
30 comprend en outre du propylèneglycol.

28. Composition de gel cosmétique transparente et douce selon la revendication 1, dans laquelle la phase d'huile
comprend des fluides siliconés.

35 29. Procédé de formation de la composition de gel cosmétique transparente et douce selon la revendication 1, com-
prenant les étapes suivantes :

a) la formation d'une phase aqueuse contenant (i) de l'eau; (ii) au moins un ingrédient cosmétiquement actif
en quantité suffisante pour avoir un effet cosmétique; (iii) au moins un agent de couplage en quantité de 10%
40 à 30%, par rapport à la composition totale, suffisante pour distribuer la phase aqueuse uniformément dans la
phase d'huile; et (iv) au moins un polypropylèneglycol;
b) la formation d'une phase à base d'huile contenant un matériau ayant un indice de réfraction dans la plage
de 1,40 à 1,50; éventuellement des fluides siliconés; et un agent tensioactif de siloxane alcoxylé substitué par
des groupes alkyle, qui est un copolyol de diméthicone, en quantité suffisante pour former une émulsion eau
45 dans l'huile dans la composition de gel cosmétique;

dans laquelle chacune de la phase aqueuse et de la phase à base d'huile a un indice de réfraction qui est déterminé
et éventuellement ajusté sur une différence entre les indices de réfraction de moins de 0,0005; le mélange de la
phase aqueuse avec la phase à base d'huile, et dans laquelle ladite composition de gel cosmétique est une émul-
50 sion eau dans l'huile et dans laquelle la composition de gel cosmétique a un indice de réfraction dans la plage de
1,4026 à 1,4150.

30. Procédé selon la revendication 29, dans lequel ledit au moins un polypropylèneglycol comprend le tripropylène-
glycol.
55
31. Procédé selon la revendication 29, dans lequel les fluides siliconés sont présents et comprennent un fluide siliconé
volatil et un fluide non volatil, et dans lequel la matériau ayant un indice de réfraction dans la plage de 1,40 à 1,50
est un émollient ayant un indice de réfraction plus élevé que celui du fluide siliconé volatil et du fluide siliconé non

26
 EP 0 845 977 B1

volatil.

32. Procédé selon la revendication 29, dans lequel, après mélange, le mélange obtenu est transféré à un récipient
distributeur pour un usage par un consommateur.
5
33. Utilisation non thérapeutique de compositions telles que définies dans la revendication 1, pour la réduction d'un
potentiel d'irritation de la peau.

34. Utilisation non thérapeutique de tripropylèneglycol dans une composition de gel cosmétique transparente et douce
10 comprenant :

a) la formation d'une phase à base aqueuse (i) d'eau; (ii) d'au moins un ingrédient cosmétiquement actif en
quantité suffisante pour avoir un effet cosmétique; et (iii) d'au moins un polypropylèneglycol;
b) une phase huileuse contenant un matériau ayant un indice de réfraction dans la plage de 1,40 à 1,50;
15 c) 10% à 30% d'au moins un agent de couplage de sorte que la phase aqueuse soit uniformément distribuée
dans la phase huileuse;
d) un agent tensioactif de siloxane alcoxylé substitué par des groupes alkyle en quantité telle que soit formée
une émulsion eau dans l'huile, dans la composition de gel cosmétique;

20 dans laquelle ladite composition de gel cosmétique est une émulsion eau dans l'huile et dans laquelle la compo-
sition de gel cosmétique a un indice de réfraction dans la plage de 1,4026 à 1,4150 pour la réduction du potentiel
d'irritation de la peau.

35. Composition selon la revendication 17, dans laquelle la quantité de tripropylèneglycol se situe dans une plage de
25 1% à 20%.

36. Utilisation non thérapeutique telle que définie dans la revendication 1 pour réduire l'azurage et laisser moins de
résidus après application.

30 37. Utilisation d'une composition telle que définie dans la revendication 1 pour la fabrication d'un médicament pour
réduire l'irritation de la peau.

35

40

45

50

55

27