1-Jurnal Pendukung Judul Skripsi Kedua-Setiawan, P. B. A. Et Al (2020) - The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel
1-Jurnal Pendukung Judul Skripsi Kedua-Setiawan, P. B. A. Et Al (2020) - The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel
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Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the
Degree of Acne Vulgaris in Students of SMA Negeri 2 Bayang
Putri Bunga Anggreno Setiawan1, Ade Teti Vani2, Budi Yulhasfi Febrianto3 , Vina Tri Septiana4
1
Fakultas Kedokteran Universitas Baiturrahmah, Padang,Indonesia
2
Bagian Histologi Fakultas Kedokteran Universitas Baiturrahmah, Padang, Indonesia
3
Bagian Bedah Fakultas Kedokteran Universitas Baiturrahmah, Padang, Indonesia
4
Bagian Radiologi Fakultas Kedokteran Universitas Baiturrahmah, Padang, Indonesia
1. INTRODUCTION
Acne vulgaris is an inflammatory skin condition caused by polysebaceous units that occurs in
adolescents and young adults characterized by comedones, papules, pustules, and nodules.1 The
distribution of acne depends on the density of pilosebaceous units, especially on the face, neck, chest,
shoulders and back. Acne vulgaris can cause scars resulting in a lack of self-confidence, and can also
lead to depression, therefore acne requires serious treatment.2
Records of the Indonesian cosmetic dermatology study group showed that there were 60% of
acne vulgaris sufferers in 2006 and 80% in 2007. The incidence of acne vulgaris is 80 to 100% in young
adults, namely 14-17 years in women, and 16-19 years in men. . In general, many teenagers have
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
39
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Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
problems with acne vulgaris because many teenagers have the wrong treatment and lack of knowledge
about acne vulgaris.3.
Adolescents who have problems with acne vulgaris due to lack of knowledge about the factors
that cause acne vulgaris (multifactorial), including genetic factors, racial factors, food factors, climate
factors, skin type factors, hygiene factors, cosmetic use factors, stress factors, infection factors and
occupational factors. Patients usually complain of a skin rash in the form of comedones, papules,
pustules, nodules, and cysts that can be accompanied by itching, areas that often appear on the face,
shoulders, upper part of the superior extremities, chest and back.
Facial hygiene can be done by using facial soap, facial soap is used at the first step in skin care.
The soap is used to clean the face from exposure to dust, pollution, dirt, and reduce sebum on the face
which can cause acne. 5 Keeping the face clean by washing the face regularly is done 2 times a day, not
only using facial soap, it needs to be supported by using a facial skin moisturizer. like aloe vera gel.6
Aloe vera in Indonesia is widely known by the public as a traditional medicinal plant because it
has many benefits and contains antioxidants consisting of monosaccharides, polysaccharides, essential
and non-essential amino acids, enzymes, minerals, vitamins, anthraquinones, proteins, lignin, salicylate,
saponins, sterols, tannins, magnesium lactate and prostaglandins. Substances that function as
antibacterial are anthraquinones, saponins and tannins. Aloe vera is used to refresh, moisturize the skin
and also has a protective effect against skin damage caused by radiation. Aloe vera also functions as an
anti-aging agent that is useful for inhibiting the thinning process of the skin and preventing the loss of
elastin fibers and increasing the water-soluble collagen content of the dermis..7
Aloe vera contains many antioxidants that function as a source of raw materials for various
products in the food, pharmaceutical and cosmetic industries. Aloe vera contains saponins that function
as cleansing and hydrating properties antiseptic, Aloe vera also has accemanans that function as anti-
virus, anti-bacterial and anti-fungal. Utilizing Aloe vera as an ingredient for making soap, is not only
able to kill bacteria, but can also smooth the skin. Lignin which functions to protect the skin to keep it
moist and retain water in the skin, so that excessive evaporation does not occur.8 The above explanation
explains the content of Aloe vera that can affect the severity of acne vulgaris. Antiacne facial cleansing
soap products that are circulating, but not yet Many studies have been conducted to determine the
effectiveness of Aloe vera in inhibiting the growth of Propionilbacterium Acnes.
This study aims to determine the effectiveness of facial soaps and gels made from Aloe vera in
inhibiting the growth of Propionibacterium acnes bacteria which is one of the factors causing acne
vulgaris. Previous research conducted by Muhammad Silpi on the effect of aloe vera gel on acne
vulgaris in class 2019 students of the Baiturrahmah University medical faculty, proved that there were
significant differences in acne vulgaris before and after administration of aloe vera gel.9 Researchers
are interested in developing previous research on aloe vera gel. against acne by adding facial soap, so
this study aims to determine the effectiveness of aloe vera gel and aloe vera soap on the degree of acne
vulgaris in students of SMA Negeri 2 Bayang.
Researchers are interested in conducting research in the southern coastal area because the
southern coast is an area close to the beach and also the weather in this area is quite hot, the risk factor
for acne vulgaris is food factors, one of which is high levels of iodine which can cause acne vulgaris,
so researchers are interested in taking samples in this area. SMA Negeri 2 Bayang which is one of the
high schools located on the south coast.8
Based on the description above, the formulation of the problem in this study is how the effect of
aloe vera soap and aloe vera gel on the level of acne vulgaris in students at SMA Negeri 2 Bayang. This
study aims to determine the effect of aloe vera facial soap and aloe vera gel on the level of acne vulgaris
on students at SMA Negeri 2 Bayang.
2. METHOD
The scope of this research covers the fields of pharmacology and dermatology. The location of
this research will be at SMA Negeri 2 Bayang Pesisir Selatan. The time of the study was carried out in
April 2021. This type of research used an experimental study with a pre-test and post-test control group
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
40
http://ejournal.seaninstitute.or.id/index.php/healt
Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
design. The sampling method used in this research is stratified random sampling. The sample required
in this study is 20 samples.
Procedure
1. Taking a history and inspection of acne vulgaris by a dermatologist on prospective samples. Samples
were obtained according to the inclusion criteria.
2. Grouping the samples according to the degree of acne vulgaris.
3. Giving aloe vera soap and aloe vera gel to the sample for 28 days.
4. Observation on the 29th day
5. Record the degree of acne vulgaris after treatment.
6. Perform data analysis to determine differences in the degree of acne vulgaris before and after
treatment.
Data analysis
The data was obtained from the pre-post test control group design which was processed using SPSS
from the data that had been obtained
Based on table 2, it was found that from 20 respondents, the most gender were 18 women (90%)
and 2 men (10%).
Acne pre and post students who are given aloe vera facial and aloe vera gel
The results showed that the frequency distribution of pre and post acne on students who were given
aloe vera facial soap and aloe vera gel treatment can be described as follows:
Table 3 Frequency Distribution of Acne Pre and post given Aloe Vera Facial Soap and Aloe
Vera Gel Students at SMA Negeri 2 Bayang
Acne pre A F %
Mild degree 0 0
Moderate Degree 10 100
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
41
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Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
Degree of Weight 0 0
Amount 10 100
Acne post A F %
Mild Degree 10 100
Moderate Degree 0 0
Degree of Weight 0 0
Amount 10 100
Based on table 3, it was found that out of 10 respondents, acne pre who was given aloe vera facial
soap and aloe vera gel were in the moderate degree, namely 10 people (100%) and acne post at the mild
degree, namely 10 people (100%).
Acne pre and post students who are given aloe vera facial soap
The results showed that the frequency distribution of pre and post acne in students who were
given aloe vera facial soap treatment can be described as follows:
Table 4 Frequency Distribution of Acne Pre and Post Treatment of Aloe Vera Facial Soap by
Students at SMA Negeri 2 Bayang
Acne pre B f %
Mild Degree 4 40
Moderate Degree 6 60
Degree of Weight 0 0
Amount 10 100
Acne post B f %
Mild Degree 8 80
Moderate Degree 2 20
Degree of Weight 0 0
Amount 10 100
Based on table 4, it was found that out of 10 respondents, the most acne pre treated with aloe vera
facial soap were in the moderate degree, namely 6 people (60%) and the most acne post was in the mild
degree, namely 8 people (80%).
Normality Test
The normality test in this study used the Shapiro-Wilk test because the research sample was <30
people and the test was carried out on each pre and post data on the treatment given aloe vera facial
soap and aloe vera gel with aloe vera facial soap.
Table 5 Normality test
Variable Signific Signific Description
ant- ance
kansi Limit
acne Pre A 0,363 0,05 Normal
acne Post 0,936 0,05 Normal
A
acne Pre B 0,144 0,05 Normal
acne Post 0,128 0,05 Normal
B
Based on the table above, the results of the Shapiro-Wilk test were obtained in the treatment
given aloe vera facial soap and aloe vera gel and aloe vera facial soap before acne obtained a
significance value of 0.363 and acne post a significance value of 0.936. Treatment with aloe vera acne
pre facial soap obtained a significance value of 0.144 and acne post a significance value of 0.128. The
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
42
http://ejournal.seaninstitute.or.id/index.php/healt
Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
results of the significance values of pre and post acne showed a significance value > 0.005, meaning
that the data distribution was normal and for statistical hypothesis testing, the paired sample t-test was
used.
Bivariate Analysis
Analisis bivariat bertujuan untuk mengetahui perbedaan antara acne pre dan post pada perlakuan
diberikan sabun wajah aloe vera dan gel aloe vera serta sabun wajah aloe vera menggunakan uji paired
sample t-test dan menganalisis perbandingan pemakaian sabun wajah aloe vera dan gel aloe vera
dengan sabun wajah aloe vera menggunakan uji independent sample t test.
Table 6. Paired Sample T Test Aloe vera Facial Soap and Aloe Vera Gel with Aloe Vera Facial
Soap
treatment IK95% differ Mark
Lower Upper ence p
Vulgaris
Pre 9.973 19.826 14.9 0,000
Vulgaris
Post
treatmen IK95% diffe Mark p
t Lowe Upper renc
r e
Vulgaris
Pre 1,494 2,306 1,9 0,000
Vulgaris
Post
Based on the table above, the results of the paired sample t-test showed that the p value of 0.000
was smaller than 0.05, meaning that there were differences between pre and post use of aloe vera facial
soap and the degree of acne vulgaris in students at SMA Negeri 2 Bayang.
Table 7. Independent Sample T Test The treatment was given aloe vera facial soap and aloe
vera gel with aloe vera facial soap
Treatmen IK95% differ Mark p
t Lower Upper ence
Acne -13.074 -0.327 -6,7 0.040
Post A
Acne -13.473 0.073
Post B
Based on the table above, the results of the independent sample t test obtained a p value of 0.040
which is smaller than 0.05, so as the basis for decision making in the independent sample t test, it can
be concluded that there is a significant difference between the average results in the treatment given
aloe vera facial soap and gel. aloe vera with aloe vera facial soap, the results showed that the use of aloe
vera facial soap and aloe vera gel was better for treating acne vulgaris in students of SMA Negeri 2
Bayang than the use of aloe vera facial soap.
DISCUSSION
Frequency distribution of patients with acne vulgaris based on age in student at SMA
Negeri 2 Bayang
Based on the research, the results obtained from 20 respondents, the age of the most students is
17 years as many as 8 people (40%), ages 15 and 16 years are the same number of 6 people each (30%)
in SMA Negeri 2 Bayang. This is because the sampling method is taken from each grade 1 to grade 3
at SMA Negeri 2 Bayang so that the age obtained varies by showing that the 15-17 year age range is
the age of early adolescence, where at that time teenagers have experienced acne vulgaris.
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
43
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Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
The results of this study are in line with previous research conducted by Sole, (2018) which states
that the adolescent age in Manado obtained at the time of the study the most was 17 years, namely
(57%), but different from this previous study conducted by Wibawa, (2019 ) the results showed that the
highest group was in the age range of 15-24 years, namely 39 people (59.1%). The difference in this
study is due to different samples so that the distribution of age is also different.9, 10
In accordance with the previous theory that acne vulgaris is a chronic inflammation of the
pilosebaceous follicles with the highest prevalence at the age of 15-18 years and the age range of 14-17
years is included in the category of early adolescence and starting to enter late adolescence, where about
85% of adolescents have experienced acne vulgaris. .
Distribution Frequency of Acne vulgaris Patients Based on Gender in Students of SMA Negeri 2
Bayang
Based on the research, the results obtained from 20 respondents, the most gender were 18 women
(90%) and 2 men (10%) in SMA Negeri 2 Bayang. This shows that women experience acne vulgaris
more than men.
The results of this study are in line with previous research conducted by Sibero, (2019) found
that acne vulgaris was more experienced by women (69.7%) than men (30.3%)12 and also Wibawa's
research (2019) found that the number of 19 male patients with acne vulgaris (28.8%) and 47 female
patients (71.2%).9
This is because women pay more attention to their appearance besides that according to the peak
severity of acne vulgaris occurs earlier in women compared to men, so it is more encouraging for
women to go to the doctor. The trigger factors for acne vulgaris in women are hormonal and cosmetic
factors. Hormones can affect the severity of acne vulgaris in women, the hormones estrogen and
progesterone play an important role in the mechanism of acne vulgaris because they are influenced by
the menstrual cycle, in women acne vulgaris will appear more days before the menstrual cycle and will
persist for more than a week after menstruation, during puberty, hormones rise. Androgens play an
important role in the blood and can cause hyperplasia and hypertrophy of the sebaceous glands so that
acne vulgaris is most common in adolescents. 13 Cosmetics can cause closed comedones with some
papulopustular lesions on the cheeks and chin, because the ingredients contained in cosmetics are
comedogenic. resulting in increased sebum production. Comedogenic ingredients such as lanolin,
petrolatum, essential oils, butyl stearate, lauryl alcohol and oleic acid. These ingredients are found in
various face creams such as foundation, moisturizer, sun protection cream which causes acne vulgaris.
Frequency Distribution of Acne vulgaris Pre and Post Giving Face Soap and Aloe Vera
Gel to Students at SMA Negeri 2 Bayang.
Based on the research, the results obtained from 10 respondents, acne vulgaris pre given the
treatment of aloe vera facial soap and aloe vera gel were in the moderate degree, namely 10 people
(100%) and post at the mild degree, namely 10 people (100%) at SMA Negeri 2 Bayang. This shows
that after being given the treatment, namely the provision of aloe vera facial soap and aloe vera gel, the
degree of acne vulgaris decreased from moderate to mild. The results of this study are in line with
Putra's research, (2020) obtained the highest degree of moderate acne vulgaris as many as 176 people
(65.2%)15 but it is different from previous research conducted by Gomarjoyo, (2019) in students of
SMKN 1 Samarinda obtained the degree of acne vulgaris most students are mild (93.2%).16
The number of respondents experienced moderate acne vulgaris before being given aloe vera soap
and gel, this was caused by many factors such as the use of cosmetics, especially in women. The cause
of acne vulgaris is the oil element excess in cosmetic products. Oil will act like oil natural and can clog
pores and the presence of dyes can aggravate acne. Acne is more commonly found in the chin and cheek
areas, compared to the forehead area, initially in the form of small bumps and lesions that look reddish.
Cosmetic acne scars less often, but can persist for years as a result of continuous use of cosmetics.17
Acne vulgaris is a disease that occurs due to inflammation of the skin polysebaceous follicles that
play a role in producing sebum and often occurs in adolescence. Clinical features that refer to acne
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
44
http://ejournal.seaninstitute.or.id/index.php/healt
Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
vulgaris include excessive oil production, non-inflammatory lesions such as open comedones and
closed comedones, and inflammatory lesions such as papules and pustules.
The decrease in the degree of acne vulgaris after being given treatment with aloe vera facial soap
and aloe vera gel, it proves that aloe vera facial soap and aloe vera gel can reduce the degree of acne
vulgaris. Aloe vera gel is proven to be effective in killing and inhibiting the growth of bacteria that
cause acne vulgaris. Aloe vera contains active substances such as saponins, tannins, and phenols.
Saponins are alkaloids that can damage bacteria (DNA and RNA), while saponins dissolve lipids in
bacterial cell membranes so that bacterial cell functions become abnormal and lysis. Tannins are
antibacterials that work by inactivating adhesins so that bacteria cannot attach to host epithelial cells.
Tannins also have antioxidant activity inhibiting tumor growth and enzymes, tannins also have
antiseptic properties that can prevent damage caused by bacteria.
Frequency Distribution of Degress of Acne vulgaris Pre and Post Giving Aloe Vera Facial
Soap to Students at AMA Negeri 2 Bayang
Based on the research, the results were obtained from 10 respondents, the most acne pre given
aloe vera facial soap was in the moderate degree, namely 6 people (60%) and the most acne post was
in the mild degree, namely 8 people (80%) at SMA Negeri 2 Bayang. This shows that after being given
treatment, namely giving aloe vera facial soap, the degree of acne vulgaris decreased from moderate to
mild, but there were still 2 people in the moderate category. This study is in line with Marliana, (2018)
which states that the ingredients contained in face wash have the ability to inhibit the growth of
Propionibacterium acnes bacteria that causes acne vulgaris.19 According to Tarek, (2021) aloe vera has
proven its effectiveness in killing and inhibiting the growth of bacteria that cause acne. vulgaris. Aloe
vera can also be used as an antiseptic and antibiotic. This aloe vera produces 6 antiseptic agents such as
lupeol, salicylic acid, urea nitrogen, cinnamonic acid, phenol and sulfur. All of these substances are
classified as antiseptics because they can kill germs or control the formation of bacteria.Knowing the
effectiveness of using aloe vera facial soap and aloe vera gel with aloe vera facial soap against the
degree of acne vulgaris in students of SMA Negeri 2 Bayang Based on the table above, the results of
the independent sample t test obtained that the p value of 0.040 is smaller than 0.05, so as the basis for
decision making in the independent sample t test, it can be concluded that there is a significant
difference between the average results of aloe vera facial soap and aloe vera gel with soap. aloe vera
face, the results showed that the use of aloe vera facial soap and aloe vera gel was better for treating
acne vulgaris in students of SMA Negeri 2 Bayang than the use of aloe vera facial soap.
Proving the effectiveness of aloe vera has previously been carried out by many studies, such as
the Silpi study, (2017) on the Effects of aloe vera gel on acne vulgaris. Pre and post treatment, the
results showed that there was a significant difference in the mean before and after being given aloe vera
gel to medical students class 2019 Faculty of Medicine. Baiturrahmah.20
The effect of using aloe vera soap and aloe vera gel can treat acne vulgaris because aloe vera
contains ingredients that are useful in reducing the degree of acne vulgaris, but the use of facial soap
that is rinsed directly causes the duration of the product content that serves to reduce the degree of acne
vulgaris shorter so that it penetrates into the skin. skin layer is not optimal. Giving aloe vera gel is better
because aloe vera gel contains the content of reducing the degree of acne vulgaris by applying aloe vera
gel to the facial skin for a long duration and can penetrate the skin layers so that the beneficial
ingredients can work effectively. Aloe vera gel includes several compounds such as vitamin E and
vitamin C and several amino acids, which can play an important role in accelerating wound healing to
such an extent that experiments have shown that vitamin C can play a role in increasing collagen
production and preventing the synthesis of DNA strands, as well as vitamin E. as a powerful antioxidant
in wound healing. Aloe vera gel has an enzymatic system of antioxidants such as glutathione peroxidase
and superoxide dismutase, which accelerate wound healing by neutralizing the effects of free radicals
generated at the wound site and with anti-inflammatory properties.
Prevention of acne vulgaris can be overcome by maintaining facial skin cleanliness, cleaning facial
skin regularly by washing your face twice a day can remove dirt, dust, oil which will reduce skin fat
and prevent bacteria from entering the polysebaceous ducts and remove dead skin on the surface of the
The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
45
http://ejournal.seaninstitute.or.id/index.php/healt
Jurnal Eduhealt, Volume 11, No. 01 September 2020
ISSN. 2087-3271
face. , reduce blackheads, and can reduce inflammation so as to minimize the possibility of acne
vulgaris.23 The ingredients contained in facial washing soap can inhibit the growth of bacteria that
cause acne vulgaris, such as benzoyl peroxide which works by forming free radicals that can inhibit
bacterial metabolism, so soap can prevent the growth of bacteria that cause acne vulgaris. Sodium
sulfacetamide has the ability to inhibit the growth of Propionibacterium acnes. Sulfur inhibits the
growth of Propionibacterium acnes and plays a role in keratinolysis, thereby closing the skin pores and
reducing the production of sebaceous glands.
4. CONCLUSION
Based on the results of research on the effectiveness of using aloe vera facial soap and aloe vera
gel on the degree of acne vulgaris in SMA Negeri 2 Bayang students, it can be concluded that giving
aloe vera facial soap and aloe vera gel provides a better improvement on the degree of acne vulgaris
than giving facial soap. aloe vera in adolescent acne vulgaris patients.
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Febrianto, Vina Tri Septiana
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The Effectiveness of Using Aloe Vera Facial Soap and Aloe Gel on the Degree of Acne Vulgaris in
Students of SMA Negeri 2 Bayang Putri Bunga Anggreno Setiawan, Ade Teti Vani, Budi Yulhasfi
Febrianto, Vina Tri Septiana
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