“Me - Scfence_ AcHurties “relating to deleclfon Ossemenl) ‘Underanding Communi Of adver: even! fotos immunizalign +o prevent UNtoWand efferds +o the Vaccine, {eClements +o Consider ‘eOhen Conducting Vaccine PV 2) Vaccine usualy Generally administered to the healthy PETSOP. 2) Vaccine May be _administned 40 birlh Cohort or to fprour. ar hiyb risk fos disease Corn plicalon 8) Sub laHion may be |more Suceptible: for Certain: Agets: ‘te Yodvease event Fetiown og immuntzall 4) The age at the time ot- immunization io Conside. with the emerqende sts Some age related “disease. 2 Benefit at fmmunization may nok be immediatley Visible ff targel disease Tncidence 1s dow 8) Dur to low ccceplance ot risk , intensive - tovestigatien. of -Semious Ager i} vare fs neces: we 4) Non- sevious AEFI Should be Carefully monitored b + Signal _poten Hal bl scause, Haig may Signal typ po loge pose le Lortb Vacetn,— [59 Apevia {access _ ans vs | va ve “ale . = _ 13) Cons rechaly, oy Consideration ok dechallenge +—1echaliy Spa ‘Pow wvatcine + Compan ito other ( + | miediehng, ib st a + foe ail : 7 at I) EP tccHve. Communt catod regan oH Safely Vaccin Fmmunizaton 1s Chilenging . Da, adverse evenl is evidang O- Serious stron, c snot G rebated: tos Virormsunizahoo “ Vocdinatfon Failuxe D may be defined based of Clinical end Or. trvnunglogical Criferfa , “where -Correlat, : aunmgats | rlankcens: for diseav! psotedion A ud primar, foflure> % , 7 lack of: Sewoconwrsion oy genopret ° Secondayt Taflure laws Claning rnmunity. ‘a f My te ; 1aA Cweale ti) -due to Vacetnee: biases Cost re Lote ) Vaccine related Ly D = mninckten @ rt is nol too/. efFicacioy O Age related) ma. ation ogains| inctuded anh’gen: 2 Sencesence sf Tmmume |@ “rncomplete overage: responsiveness] ol alrain, Sevotyre, © xnsutticten} O¥_Suhoptim Jenotype antigenic tromune response, Variants ot escape mutant @Ornterhere With other ethat Con Comme Vaiceine. iofective agent Preventable dtseare © Glanning Strompunt _) Antigenic interterance. ® Suto plimal heatih Slatus Tmmunotoai cal interlenance G manufactersing ve kegteal @_pre- exiding’ infection with 9. Balch vavialion _Pathoren thegeted by vaccine. Quality Variaton @) srmbouna eerste Atuopy cdletects ® © Naccine- vaccine inkvadi: =a | ~ Oadmipistrati 10. . umber time Orn} ob _primaty [ boosty Vaccinatio dsoeJ ' tne Senes incomplete. Compliance with the fo mended Scudule. @ shortage a Vaccine En Leading 400 08m of recnmineded ‘ : incomplete Vaccination ly “Vacei nation: qe vetated ot ie re th ie beyond 0 evpivyU used ss 1 nd ‘ge} 7 =e) Cc i en | Fromuotzaiien = Medical inciden| that _-lakes Place alten the | Iromuniization Catises Concern + is ibetived +o be Caused by im munization _ [ert is recommended that to observe benef teiarfs: receiving Varceing for IS- 30 Min ca ClasailFeatinn of AEE =. Oo Vaccine reaction = oi pri Event! caused bys inherant properties of vaccine i 2 programe Erroy > Event Caused by an error 19 Vaccine prepralion. transport Shérlage ot Adminis} ration © Cofnciden| eet Saas ‘ 1 TENE f Event that happen often immunizaHon but nof Cetttsed by Vaccine. C Tost by Chance) : ; a ; ® =ojection reaction > f ise) Tather ethan Abe! wacet awl i Event from an jeby Or pain from rea? tices! © Onno —> 4 Even) ‘Cause: Caunol the detenminedtas BC testa ea ee t b)cH = °) gles > irorob fopenid i febrile: Seizure t ssp Cu acu Scierasiog pancesh { Bronchial.” Neumitis Apap A) Telanud > Specifics rgides veMect at AEE Plies YO Sarre Syndrome —> Killed: influenza Gy | Wace ine a) Chock =" pests Vaccine » DeT ‘ 1 3d pense _ “Mepis: Be, pei ta q Meniggecocel : ‘ A) Thrombeay lope nia MMR.2 Taveshigation - of Act = Describe About Vaccine Pv> Give bricl About « ’ =n stigaton of AEFr vyouva [Sip > Confira Repod > _patienl _medfeal file. | Step 2 = Envestigalion albouwt paltenl about | +he event O)ommunization history 6) previous medica) history 2 Family history 9) Condistor - under Which Vacetne Wan Shipped § sbored (vet) Step igi sot > Asses the Service. aeeine Vial moni}s : OF Vaceine Storage. SLR b) Diluent shoraqe, ©) Reconsitusion process ¢ time Kept 2» Immunizaton Service Ste p4 > Formulate hypothesis On the possibl Care ot event. Shp © > Tes} - hypothesis. lateorabory test. Step ¢ > Conctude, investigation 4 a)Reach Conclurion bo: Fake Corrective acHon. Pyecommended ov furtear action,. [Cluster of [ Aeey ; a fi ______ no. An Cases got ———} Au: Cases got —-NQ7] Tan Cases Come om one facility eal Same _Voctine r g pot Hol? ° ote Similoe tines tn _otber Who dideil et voccine. s yes Contac dent