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Printed by: USP NF Official Date: Official as of 01-Jan-2018 Document Type: USP @2024 USPC
Do Not Distribute DOI Ref: eb2np DOI: https://doi.org/10.31003/USPNF_M2365_03_01
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the result obtained to calculate the Aluminum/zirconium
Aluminum Zirconium atomic ratio and the (Aluminum plus zirconium)/chloride atomic
Tetrachlorohydrate ratio.
Aluminum/zirconium atomic ratio—Divide the
percentage of aluminum found in the test for Content of
Al y Zr(OH) 3y+4-x Cl x · nH 2 O aluminum by the percentage of zirconium found in the test for
Content of zirconium, and multiply by 92.97/26.98, in which
» Aluminum Zirconium Tetrachlorohydrate is a 92.97 is the atomic weight of zirconium corrected for 2%
polymeric, loosely hydrated complex of basic hafnium content, and 26.98 is the atomic weight of
aluminum zirconium chloride that encompasses a aluminum: the ratio is between 2.0:1 and 5.99:1.
Content of chloride—Using Aluminum Zirconium
range of aluminum-to-zirconium atomic ratios Tetrachlorohydrate instead of Aluminum Zirconium
between 2.0:1 and 5.99:1 and a range of Octachlorohydrate, proceed as directed in the test for Content
(aluminum plus zirconium)-to-chloride atomic of chloride under Aluminum Zirconium Octachlorohydrate. Use
ratios between 1.5:1 and 0.9:1. It contains not less the result obtained to calculate the (Aluminum plus zirconium)
than 90.0 percent and not more than 110.0 /chloride atomic ratio.
(Aluminum plus zirconium)/chloride atomic ratio—
percent of the labeled amount of anhydrous Calculate the (aluminum plus zirconium)/chloride atomic ratio
aluminum zirconium tetrachlorohydrate. by the formula:
Packaging and storage—Preserve in well-closed [(Al/26.98) + (Zr/92.97)]/(Cl/35.453)
containers.
Labeling—The label states the content of anhydrous in which Al, Zr, and Cl are the percentages of aluminum,
al
aluminum zirconium tetrachlorohydrate. zirconium, and chloride as determined in the tests for Content
Identification—A solution (1 in 10) responds to the test for of aluminum, Content of zirconium, and Content of chloride,
Chloride á191ñ. respectively; 26.98 is the atomic weight of aluminum; 92.97 is
pH á791ñ: between 3.0 and 5.0, in a solution [15 in 100 (w/ the atomic weight of zirconium corrected for 2% hafnium
w)]. content; and 35.453 is the atomic weight of chlorine: the ratio
Arsenic,Method I á211ñ: 2 µg per g.
Limit of iron—Using Aluminum Zirconium
Tetrachlorohydrate instead of Aluminum Zirconium
ci is between 1.5:1 and 0.9:1.
Assay—Calculate the percentage of anhydrous aluminum
zirconium tetrachlorohydrate in the Aluminum Zirconium
Octachlorohydrate, proceed as directed in the test for Limit Tetrachlorohydrate by the formula:
of iron under Aluminum Zirconium Octachlorohydrate. The
ffi
specified result is obtained (150 µg per g limit). Al({26.98y + 92.97 + 17.01[3y + 4 − (y + 1)/z] + 35.453(y + 1)
Content of aluminum—Using Aluminum Zirconium /z}/26.98y)
Tetrachlorohydrate instead of Aluminum Zirconium
Octachlorohydrate, proceed as directed in the test for Content in which Al is the percentage of aluminum found in the test
of aluminum under Aluminum Zirconium Octachlorohydrate. for Content of aluminum, y is the aluminum/zirconium atomic
Use the result obtained to calculate the Aluminum/zirconium ratio found in the test for Aluminum/zirconium atomic ratio, z
O
atomic ratio and the (Aluminum plus zirconium)/chloride is the (aluminum plus zirconium)/chloride atomic ratio found
atomic ratio. in the test for (Aluminum plus zirconium)/chloride atomic ratio,
Content of zirconium—Using Aluminum Zirconium 26.98 is the atomic weight of aluminum, 92.97 is the atomic
Tetrachlorohydrate instead of Aluminum Zirconium weight of zirconium corrected for 2% hafnium content,
Octachlorohydrate, proceed as directed in the test for Content 17.01 is the molecular weight of the hydroxide anion (OH),
of zirconium under Aluminum Zirconium Octachlorohydrate. Use and 35.453 is the atomic weight of chlorine (Cl).
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