TITANIUM TETRAISOPROPOXIDE MATERIAL SAFETY DATA SHEET

CAS NO 546-68-9 SDS/MSDS

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Titanium Tetraisopropoxide

CAS-No. : 546-68-9
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Industrial & for professional use only.
1.3 Details of the supplier of the safety data sheet
Company : Central Drug House (P) Ltd
7/28 Vardaan House
New Delhi -110002
INDIA
Telephone : +91 11 49404040
Email : [email protected]
1.4 Emergency telephone number
Emergency Phone # : +91 11 49404040 (9:00am - 6:00 pm) [Office hours]

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008
Flammable liquids (Category 3), H226
Eye irritation (Category 2), H319
Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram

Signal word Warning

Hazard statement(s)
H226 Flammable liquid and vapour.
H319 Causes serious eye irritation.
H336 May cause drowsiness or dizziness.
Precautionary statement(s)
P280 Wear eye protection/ face protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Page 1 of 6
 P337 + P313 If eye irritation persists: Get medical advice/ attention.
P403 + P235 Store in a well-ventilated place. Keep cool.
Supplemental Hazard none
Statements
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.1 Substances
Synonyms : Tetraisopropyl orthotitanate
TYZOR® organic titanate

Formula : C12H28O4Ti
Molecular weight : 284.22 g/mol
CAS-No. : 546-68-9
EC-No. : 208-909-6

Hazardous ingredients according to Regulation (EC) No 1272/2008

Component Classification Concentration
Titanium tetraisopropanolate
CAS-No. 546-68-9 Flam. Liq. 3; Eye Irrit. 2; STOT <= 100 %
EC-No. 208-909-6 SE 3; H226, H319, H336

For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Titanium/titanium oxides
Flash back possible over considerable distance., Container explosion may occur under fire conditions.

Page 2 of 6
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
Use water spray to cool unopened containers.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Beware of vapours accumulating to form explosive concentrations.
Vapours can accumulate in low areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Handle under nitrogen, protect from moisture. Store under nitrogen. Store in cool place. Keep container
tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed
and kept upright to prevent leakage.
Hydrolyses readily. Handle and store under inert gas.
Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. W ash hands before breaks and
at the end of workday.

Personal protective equipment

Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Body Protection
Impervious clothing, Flame retardant antistatic protective clothing., The type of protective
equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace.

Page 3 of 6
 Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use (US) or type ABEK (EN
14387) respirator cartridges as a backup to enginee protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
Colour: light yellow
b) Odour alcohol-like
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing Melting point/range: 14 - 17 °C
point
f) Initial boiling point and 232 °C
boiling range
g) Flash point 45 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower No data available
flammability or
explosive limits
k) Vapour pressure 1.33 hPa at 63 °C
l) Vapour density No data available
m) Relative density 0.96 g/mL at 20 °C
n) Water solubility insoluble
o) Partition coefficient: n- No data available
octanol/water
p) Auto-ignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
May decompose on exposure to moist air or water.
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available

Page 4 of 6
10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
Strong oxidizing agents, Strong acids
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Titanium/titanium oxides
Other decomposition products - No data available
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 7,236 mg/kg(Titanium tetraisopropanolate)
LC50 Inhalation - Rat - 4 h - 7.78 mg/l(Titanium tetraisopropanolate)
Remarks: Material may be irritating to mucous membranes and upper respiratory tract.
LD50 Dermal - Rabbit - > 15.5 g/kg(Titanium tetraisopropanolate)
Skin corrosion/irritation
Skin - Rabbit(Titanium tetraisopropanolate)
Result: Mild skin irritation - 24 h
Serious eye damage/eye irritation
Eyes - Rabbit(Titanium tetraisopropanolate)
Result: Eye irritation - 24 h
Respiratory or skin sensitisation
No data available(Titanium tetraisopropanolate)
Germ cell mutagenicity
No data available(Titanium tetraisopropanolate)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available(Titanium tetraisopropanolate)
Specific target organ toxicity - single exposure
May cause drowsiness or dizziness.(Titanium tetraisopropanolate)
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available(Titanium tetraisopropanolate)
Additional Information
RTECS: NT8060000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.(Titanium tetraisopropanolate)

SECTION 12: Ecological information

12.1 Toxicity
No data available
Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 590 mg/l - 48 h(Titanium
other aquatic tetraisopropanolate)
invertebrates
Toxicity to algae EC10 - Algae - 201 mg/l (Titanium tetraisopropanolate)
Toxicity to bacteria EC50 - Bacteria - 1,050 mg/l - 16 h(Titanium tetraisopropanolate)
12.2 Persistence and degradability
No data available
Page 5 of 6
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available(Titanium tetraisopropanolate)
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber b highly flammable. Offer
surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information

14.1 UN number
ADR/RID: 2413 IMDG: 2413 IATA: 2413
14.2 UN proper shipping name
ADR/RID: TETRAPROPYL ORTHOTITANATE
IMDG: TETRAPROPYL ORTHOTITANATE
IATA: Tetrapropyl orthotitanate
14.3 Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of H-Statements referred to under sections 2 and 3.
H226 Flammable liquid and vapour.
H319 Causes serious eye irritation.
H336 May cause drowsiness or dizziness.
Further information
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Central Drug House (P) Ltd and its Affiliates shall not be
held liable for any damage resulting from handling or from contact with the above product. See
www.cdhfinechemical.com for additional terms and conditions of sale.

Page 6 of 6