B. Pharm.
Sixth Semester
35171 : Biopharmaceutics - II: T-6,5
P. Pages :I AW - 2317
Time : Three Hours ,illilll lllll, JlLlll Max. Marks ; 60
Notes : l. All question carry equal marks.
2. Answ€! any live questions.
3. lllustrate your answcr necessar)' lvith the help ofneat sketches.
4. Use ofpen Blue/Black ink/refill only for writing the answer book.
1. Discuss non linear pharmacokinetics in details. l2
Give details ofArea under curve and discuss Dethods of it's estimation 12
.'. Wbat do you mean by mdtiple dose regimens. Add a r1otc on drug accurnulation in the 't2
body.
4. Which are the differcnt facto$ affccting clinical response t2
a) Discuss various drug intcractions in absorytion and distdbution process. 6
b) Write about tho estimatioD ofclimir)ation halflife lrom urine data. 6
6 Describe one compa..tment open modcl lbr IV bolus injection. t2
7 Write short lotes on sny trYo, 12
a) Absorption mte constant.
b) Clearance.
c) Voluineofdistribution.
AW - 2317 I