Safety Data Sheet

Revision Number: 001.2 Issue date: 06/16/2022

1. PRODUCT AND COMPANY IDENTIFICATION

Product name: LOCTITE 4031 MED. INSTANT IDH number: 229805
ADHESIVE known as 4031 Prism®
Medical Device Ins
Product type/use: Cyanoacrylate Item number: 18683
Restriction of Use: None identified Region: United States
Company address: Contact information:
Henkel Corporation Telephone: +1 (860) 571-5100
One Henkel Way MEDICAL EMERGENCY Phone: Poison Control Center
Rocky Hill, Connecticut 06067 1-877-671-4608 (toll free) or 1-303-592-1711
TRANSPORT EMERGENCY Phone: CHEMTREC
1-800-424-9300 (toll free) or 1-703-527-3887
Internet: www.henkelna.com

2. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
WARNING: BONDS SKIN IN SECONDS.
COMBUSTIBLE LIQUID.
CAUSES EYE IRRITATION.

HAZARD CLASS HAZARD CATEGORY

FLAMMABLE LIQUID 4
EYE IRRITATION 2B

PICTOGRAM(S)
None

Precautionary Statements

Prevention: Keep away from heat, sparks, open flames, hot surfaces - no smoking. Wash affected area
thoroughly after handling. Wear protective gloves, eye protection, and face protection.
Response: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical attention. In case of fire:
Use foam, dry chemical or carbon dioxide to extinguish.
Storage: Store in a well-ventilated place. Keep cool.
Disposal: Dispose of contents and/or container according to Federal, State/Provincial and local
governmental regulations.

Classification complies with OSHA Hazard Communication Standard (29 CFR 1910.1200) and is consistent with the provisions of the
United Nations Globally Harmonized System of Classification and Labeling of Chemicals (GHS).

See Section 11 for additional toxicological information.

3. COMPOSITION / INFORMATION ON INGREDIENTS

Hazardous Component(s) CAS Number Percentage*
Beta-Methoxyethyl Cyanoacrylate 27816-23-5 80 - 100

* Exact percentages may vary or are trade secret. Concentration range is provided to assist users in providing appropriate protections.

IDH number: 229805 Product name: LOCTITE 4031 MED. INSTANT ADHESIVE known as 4031 Prism® Medical Device Ins
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 4. FIRST AID MEASURES
Inhalation: Move to fresh air. If symptoms persist, seek medical advice. If not breathing,
give artificial respiration. If breathing is difficult, oxygen should be
administered by qualified personnel.

Skin contact: Rinse with running water and soap. Do not pull bonded skin apart. It may be
gently peeled apart using a blunt object such as a spoon, preferably after
soaking in warm soapy water. If lips are accidentally stuck together apply
warm water to the lips and encourage maximum wetting and pressure from
saliva inside the mouth. Peel or roll lips apart. Do not try to pull the lips apart
with direct opposing action. If symptoms develop and persist, get medical
attention.

Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15
minutes. Seek medical attention immediately. Do not force eye open. Medical
advice should be sought in case solid particles of cyanoacrylate trapped
behind the eyelid cause any abrasive damage.

Ingestion: Seek immediate medical attention. Do not induce vomiting. Never give
anything by mouth to an unconscious person. Ensure breathing passages are
not obstructed. The product will polymerize rapidly and bond to the mouth
making it almost impossible to swallow. Saliva will separate any solidified
product in several hours. Prevent the patient from swallowing any separated
mass.

Symptoms: See Section 11.

Notes to physician: Surgery is not necessary to separate accidentally bonded tissues. Experience
has shown that bonded tissues are best treated by passive, non-surgical first
aid. If rapid curing has caused thermal burns they should be treated
symptomatically after adhesive is removed.

5. FIRE FIGHTING MEASURES

Extinguishing media: Use extinguishing measures appropriate to local circumstances and the
surrounding environment. Water spray (fog), foam, dry chemical or carbon
dioxide.

Special firefighting procedures: Wear self-contained breathing apparatus and full protective clothing, such as
turn-out gear. Keep unnecessary personnel away. In case of fire, keep
containers cool with water spray.

Unusual fire or explosion hazards: None

Hazardous combustion products: Toxic fumes. Irritating vapors. Oxides of carbon.

6. ACCIDENTAL RELEASE MEASURES

Use personal protection recommended in Section 8, isolate the hazard area and deny entry to unnecessary and
unprotected personnel.

Environmental precautions: Do not allow product to enter sewer or waterways. Prevent further leakage or
spillage if safe to do so.

Clean-up methods: Ensure adequate ventilation. Wear appropriate personal protective equipment.
Do not use cloths for mopping up. Flood with water to complete polymerization
and scrape off the floor. Cured material can be disposed of as non-hazardous
waste. Refer to Section 8 "Exposure Controls / Personal Protection" prior to
clean up. Cured material can be disposed of as non-hazardous waste.

IDH number: 229805 Product name: LOCTITE 4031 MED. INSTANT ADHESIVE known as 4031 Prism® Medical Device Ins
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 7. HANDLING AND STORAGE
Handling: Prevent contact with eyes, skin and clothing. Do not breathe vapor and mist.
Wash thoroughly after handling. Use only with adequate ventilation. Keep
container closed. See Section 8 of the SDS for Personal Protective
Equipment. Avoid contact with fabric or paper goods. Contact with these
materials may cause rapid polymerization which can generate smoke and
strong irritating vapors, and cause thermal burns. When using, do not eat,
drink or smoke.

Storage: Keep in a cool, well ventilated area away from heat, sparks and open flame.
Keep container tightly closed until ready for use.

8. EXPOSURE CONTROLS / PERSONAL PROTECTION

Employers should complete an assessment of all workplaces to determine the need for, and selection of, proper
exposure controls and protective equipment for each task performed.

Hazardous Component(s) ACGIH TLV OSHA PEL AIHA WEEL OTHER

Beta-Methoxyethyl Cyanoacrylate None None None 0.2 ppm TWA

Engineering controls: Provide adequate local exhaust ventilation to maintain worker exposure below
exposure limits.

Respiratory protection: Use NIOSH approved respirator if there is potential to exceed exposure
limit(s).

Eye/face protection: Wear safety glasses with side shields. Full face protection should be used if
the potential for splashing or spraying of product exists.

Skin protection: Use chemical resistant, impermeable clothing including gloves and either an
apron or body suit to prevent skin contact. Use nitrile gloves and aprons as
necessary to prevent contact. Do not use PVC, nylon or cotton. The
information provided on personal protective equipment is for guidance
purposes only. A full risk assessment should be conducted prior to using this
product to determine the appropriate personal protective equipment to suit
local conditions. Personal protective equipment should conform to the
relevant EN standard.

9. PHYSICAL AND CHEMICAL PROPERTIES

Physical state: Liquid
Color: Colorless
Odor: None
Odor threshold: Not available.
pH: Not applicable
Vapor pressure: < 0.2 mm hg < 0.3 mbar < 700 mbar (50 °C (122°F))
Boiling point/range: > 300 °F (> 148.9 °C)None > 149 °C (> 300.2 °F)None
Melting point/ range: Not available.
Specific gravity: > 0.1
Vapor density: Not available.
Flash point: 80 - 93 °C (176°F - 199.4 °F)
Flammable/Explosive limits - lower: Not available.
Flammable/Explosive limits - upper: Not available.
Autoignition temperature: Not available.
Flammability: Not applicable
Evaporation rate: Not available.
Solubility in water: Polymerises in presence of water.
Partition coefficient (n-octanol/water): Not available.
VOC content: < 2 %; < 20 g/l (California SCAQMD Method 316B) (Estimated)
Viscosity: 1,100.0 - 1,650.0 mPa.s
Decomposition temperature: Not available.

IDH number: 229805 Product name: LOCTITE 4031 MED. INSTANT ADHESIVE known as 4031 Prism® Medical Device Ins
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 10. STABILITY AND REACTIVITY
Stability: Stable under recommended storage conditions.

Hazardous reactions: Rapid exothermic polymerization will occur in the presence of water, amines, alkalis and
alcohols.

Hazardous decomposition None

products:

Incompatible materials: Water. Alcohols. Amines. Bases.

Reactivity: Not available.

Conditions to avoid: Keep away from heat, ignition sources and incompatible materials. Protect from direct sunlight.
Store away from incompatible materials.

11. TOXICOLOGICAL INFORMATION

Relevant routes of exposure: Skin, Inhalation, Eyes

Potential Health Effects/Symptoms

Inhalation: May cause respiratory tract irritation. Exposure to vapors above the established exposure limit
results in respiratory irritation, which may lead to difficulty in breathing and tightness in the
chest.
Skin contact: Bonds skin in seconds. May cause skin irritation. Cyanoacrylates have been reported to cause
allergic reaction but due to rapid polymerization at the skin surface, an allergic response is rare.
Cyanoacrylates generate heat on solidification. In rare circumstances a large drop will burn the
skin. Cured adhesive does not present a health hazard even if bonded to the skin.
Eye contact: Irritating to eyes. Causes excessive tearing. Eyelids may bond.
Ingestion: Not expected under normal conditions of use. Not expected to be harmful by ingestion. Rapidly
polymerizes (solidifies) and bonds in mouth. It is almost impossible to swallow.

Hazardous Component(s) LD50s and LC50s Immediate and Delayed Health Effects
Beta-Methoxyethyl Cyanoacrylate None Irritant, Allergen

OSHA Carcinogen
Hazardous Component(s) NTP Carcinogen IARC Carcinogen
(Specifically Regulated)
Beta-Methoxyethyl Cyanoacrylate No No No

12. ECOLOGICAL INFORMATION

Ecological information: Not available.

13. DISPOSAL CONSIDERATIONS

Information provided is for unused product only.

Recommended method of disposal: Follow all local, state, federal and provincial regulations for disposal.

14. TRANSPORT INFORMATION

The transport information provided in this section only applies to the material/formulation itself, and is not specific to any
package/configuration.

U.S. Department of Transportation Ground (49 CFR)

Proper shipping name: Combustible liquid, n.o.s. (Cyanoacrylate ester)
Hazard class or division: Combustible Liquid
Identification number: NA 1993
Packing group: III

International Air Transportation (ICAO/IATA)

IDH number: 229805 Product name: LOCTITE 4031 MED. INSTANT ADHESIVE known as 4031 Prism® Medical Device Ins
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 Proper shipping name: Not regulated
Hazard class or division: None
Identification number: None
Packing group: None

Water Transportation (IMO/IMDG)

Proper shipping name: Not regulated

Hazard class or division: None
Identification number: None
Packing group: None

15. REGULATORY INFORMATION

United States Regulatory Information

TSCA 8 (b) Inventory Status: All components are listed as active or are exempt from listing on the Toxic Substances
Control Act (TSCA) inventory.
TSCA 12 (b) Export Notification: None above reporting de minimis

CERCLA/SARA Section 302 EHS: None above reporting de minimis.

CERCLA/SARA Section 311/312: Reactive, Fire, Immediate Health
CERCLA/SARA Section 313: This product contains the following toxic chemicals subject to the reporting requirements of
section 313 of the Emergency Planning and Community Right-To-Know Act of 1986 (40
CFR 372). Beta-Methoxyethyl Cyanoacrylate (CAS# 27816-23-5).

California Proposition 65: No California Proposition 65 listed chemicals are known to be present.

Canada Regulatory Information

CEPA DSL/NDSL Status: All components are listed on or are exempt from listing on the Canadian Domestic
Substances List.

16. OTHER INFORMATION

This safety data sheet contains changes from the previous version in sections: First issue.

Prepared by: Product Safety and Regulatory Affairs

Issue date: 06/16/2022

DISCLAIMER: The data contained herein are furnished for information only and are believed to be reliable. However, Henkel
Corporation and its affiliates (“Henkel”) does not assume responsibility for any results obtained by persons over whose methods
Henkel has no control. It is the user’s responsibility to determine the suitability of Henkel’s products or any production methods
mentioned herein for a particular purpose, and to adopt such precautions as may be advisable for the protection of property and
persons against any hazards that may be involved in the handling and use of any Henkel’s products. In light of the foregoing,
Henkel specifically disclaims all warranties, express or implied, including warranties of merchantability and fitness for a particular
purpose, arising from sale or use of Henkel’s products. Henkel further disclaims any liability for consequential or incidental damages
of any kind, including lost profits.

This Safety Data Sheet has been generated based on OSHA Hazard Communication Standard (29 CFR 1910.1200) and provides
information in accordance with U.S. federal law only. No warranty or representation of any kind is given with respect to the
substantive or export laws of any other jurisdiction or country. Please confirm that the information provided herein conforms to the
substantive export or other law of any other jurisdiction prior to export. Please contact Henkel Product Safety and Regulatory
Affairs for additional assistance.

IDH number: 229805 Product name: LOCTITE 4031 MED. INSTANT ADHESIVE known as 4031 Prism® Medical Device Ins
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