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LIFE CHEMISTRY RESEARCH
Biological Systems
LIFE CHEMISTRY RESEARCH
Biological Systems

Edited by
Roman Joswik, PhD, Gennady E. Zaikov, DSc, and
A. K. Haghi, PhD
CRC Press Apple Academic Press, Inc
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ABOUT THE EDITORS

Roman Joswik, PhD

Roman Joswik, PhD, is Director of the Military Institute of Chemistry and Ra-
diometry in Warsaw, Poland. He is a specialist in the field of physical chemistry,
chemical physics, radiochemistry, organic chemistry, and applied chemistry. He
has published several hundred original scientific papers as well as reviews in the
field of radiochemistry and applied chemistry.

Gennady E. Zaikov, DSc

Gennady E. Zaikov, DSc, is Head of the Polymer Division at the N. M. Emanuel
Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia,
and Professor at Moscow State Academy of Fine Chemical Technology, Russia,
as well as Professor at Kazan National Research Technological University,
Kazan, Russia. He is also a prolific author, researcher, and lecturer. He has re-
ceived several awards for his work, including the Russian Federation Scholar-
ship for Outstanding Scientists. He has been a member of many professional
organizations and on the editorial boards of many international science journals.

A. K. Haghi, PhD
A. K. Haghi, PhD, holds a BSc in urban and environmental engineering from
University of North Carolina (USA); a MSc in mechanical engineering from
North Carolina A&T State University (USA); a DEA in applied mechanics,
acoustics and materials from the Université de Technologie de Compiègne
(France); and a PhD in engineering sciences from the Université de Franche-
Comté (France). He is the author and editor of 165 books as well as 1,000
published papers in various journals and conference proceedings. Dr. Haghi
has received several grants, consulted for a number of major corporations, and
is a frequent speaker to national and international audiences. Since 1983, he
served as a professor at several universities. He is currently Editor-in-Chief
of the International Journal of Chemoinformatics and Chemical Engineering
and Polymers Research Journal and on the editorial boards of many interna-
tional journals. He is a member of the Canadian Research and Development
Center of Sciences and Cultures (CRDCSC), Montreal, Quebec, Canada.
CONTENTS

List of Contributors.........................................................................................xi
List of Abbreviations...................................................................................... xv
List of Symbols............................................................................................. xvii
Preface.......................................................................................................... xix

PART I: BIOLOGICAL MEDICINE

1. A Step Toward Personalized Medicine...........................................................3
I. R. Oviya

2. Treating Fungal Dermatophytic Infections.................................................13

M. Sharanya and R. Sathishkumar

3. A Note on an Integrated Holistic Approach for Cancer Pain....................43

M. Sharanya and R. Sathishkumar

4. System for Complex Express Analysis of Microbical Infection,

as Well as Biotesting of Various Media, Products and Preparations........57
V. S. Sibirtsev

5. A Study on the Influence of the Treatment by the Cleaned Soluble

Proteins to the Fragmented Sarcoplasmic Reticulum................................61
O. M. Alekseeva

6. A Research Note on Features of Water Vapor Sorption of Chitosan

Medicinal Films..............................................................................................77
Angela S. Shurshina, Elena I. Kulish, and Sergei S. Kolesov

7. A Research Note on Creation of Film Chitosan Coverings with the

Included Medicinal Substances....................................................................87
A. S. Shurshina and E. I. Kulish

PART II: BIOLOGICAL MATERIALS

8. Dimebon Effect on the Fluidity of Mice Synaptosomal Membrane
by EPR Spin Labeling Method.....................................................................97
N. Yu. Gerasimov, O. V. Nevrova, V. V. Kasparov, A. L. Kovarskij, A. N. Goloshchapov,
and E. B. Burlakova
viii Contents

9. Bioconversion of Solid Organic Wastes by Maggots of Black

Soldier Flies (Hermetia illucens).................................................................109
A. I. Bastrakov, A. A. Zagorinsky, A. A. Kozlova, and N. A. Ushakova

10. Chondrogenic Differentiation of Human Adipose Tissue Derived

Stromal Cells................................................................................................ 115
I. P. Savchenkova

11. Investigation of Properties of Fito-Stimulate Cyano-Bacterial

Communities Obtained from Lower Volga Ecosystems...........................125
Bataeva Yulia

12. A Research Note on Heavy Metals Change Effects of Piracetam on

Learning and Memory.................................................................................131
O. V. Karpukhina, K. Z. Gumargalieva, S. B. Bokieva, and A. N. Inozemtsev

13. Investigation on the Action of Two Types of Biological Active

Substances to the Soluble Proteins that Enriched the Animal’s Blood
Serum............................................................................................................139
O. M. Alekseeva and Yu. A. Kim

14. Mechanism of Protective Action of Antiozonants.....................................155

S. D. Razumovsky, V. V. Podmasteryev, and G. E. Zaikov

15. Synthesis of 3′-α-fluoronucleosides Using Pyrimidine Nucleoside

Phosphorylase of Thermus thermophilus and Purine Nucleoside
Phosphorylase of Escherichia coli..............................................................171
A. I. Beresnev, S. V. Kvach, G. G. Sivets, and A. I. Zinchenko

PART III: BIOLOGICAL SCIENCE

16. Application Stable Radicals for Study of Behavior of
Biological Systems........................................................................................183
M. D. Goldfein and E. G. Rozantsev

17. Biopharmaceuticals: An Introduction to Biotechnological Issues and

Practices........................................................................................................199
Sanjay Kumar Bharti and Debarshi Kar Mahapatra

18. Application Efficiency of Microbial Preparation Designed to

Intensify Disposal of Lipid Compounds in Wastewaters..........................219
M. S. Chirikova, T. P. Shakun, and A. S. Samsonova

19. Volatile Steroids as Potential Regulators of Reproduction in the

House Mouse................................................................................................227
M. A. Klyuchnikova and V. V. Voznessenskaya
Contents ix

20. Olfactory Function as Marker of Neurodegenerative Disorders:

Tests for Olfactory Assessment and Its Applicability for the Russian
Population.....................................................................................................239
V. V. Voznessenskaya, A. E. Voznesenskaya, М. А. Klyuchnikova, and Е. I. Rodionova

21. Modification of Receptor Status in Groups of Proliferative Activity

of Breast Carcinomas...................................................................................247
A. A. Brilliant, S. V. Sazonov, and Y. M. Zasadkevich

22. A Research Note on Resuscitation of Viable but Nonculturable

Probiotic Bacteria........................................................................................257
Yu. D. Pakhomov, L. P. Blinkova, O. V. Dmitrieva, O. S. Berdyugina, and
N. N. Skorlupkina

23. Immunological Databases and Its Role in Immunological Research......265

Anamika Singh and Rajeev Singh

24. Effect of Alkylresorcinols on the Chitolytic Activity of Lysozyme and

Papain...........................................................................................................275
E. I. Martirosova, N. A. Grebenkina, and I. G. Plashchina

25. A Research Note on Biotechnological Preparations for Enhancing

the Quality of Domestic Fish Mixed Feed..................................................285
D. S. Pavlov, N. А. Ushakova, V. G. Pravdin, L. Z. Кrаvtsovа, С. А. Liman, and
S. V. Ponomarev

26. A Case Study on Development of a New Aerobic-Anaerobic

Bioremediation Technology.........................................................................291
Sergey Gaydamaka and Valentina P. Murygina Lomonoso

27. Development of Nontoxic Methods of Rodent Population Control as

an Alternative Approach for Big Cities......................................................305
V. V. Voznessenskaya and T. V. Malanina

Index..............................................................................................................317
LIST OF CONTRIBUTORS

O. M. Alekseeva
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, ul. Kosygina, 4,
Moscow, 119334; E-mail: [email protected]

A. I. Bastrakov
A.N. Severtsov Institute of Ecology and Evolution, RAS, 33 Leninskij prosp., Moscow, 119071, Russia.

O. S. Berdyugina
FGBU “I.I. Mechnikov Research Institute for Vaccines and Sera” RAMS., Moscow 105064 Maliy
Kazenniy per. 5a. E-mail [email protected]

A. I. Beresnev
Institute of Microbiology, National Academy of Sciences, 220141, Minsk, Belarus.

Sanjay Kumar Bharti

School of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur,
Chattisgarh, India

L. P. Blinkova
FGBU “I. I. Mechnikov Research Institute for Vaccines and Sera” RAMS. Moscow 105064 Maliy Ka-
zenniy per. 5a. e-mail [email protected].

S. B. Bokieva
N. N. Semenov Institute of Chemical Physics, RAS, Moscow, Russia

A. A. Brilliant
GBUZSO Institute of Medical Cell Technologies, 620036 Yekaterinburg.

E. B. Burlakova
Emanuel Institute of Biochemical Physics RAS, 119334, Moscow, Russia

M. S. Chirikova
Institute of Microbiology, National Academy of Sciences, Belarus, 220141, Minsk, Belarus, E-mail:
[email protected].

O. V. Dmitrieva
FGBU “I. I. Mechnikov Research Institute for Vaccines and Sera” RAMS., Moscow 105064 Maliy Ka-
zenniy per. 5a. e-mail [email protected].

Sergey Gaydamaka
Moscow State University, Chemistry Faculty, Department of Chemical Enzymology. 119991, Moscow,
Russia.

N. Yu. Gerasimov
Emanuel Institute of Biochemical Physics RAS, 119334, Moscow, Russia

M. D. Goldfein
Saratov State University named after N.G. Chernyshevsky, Russia, [email protected]
xii List of Contributors

A. N. Goloshchapov
Emanuel Institute of Biochemical Physics RAS, 119334, Moscow, Russia

N. A. Grebenkina
Higher Chemical College, RAS, Moscow, Russia

K. Z. Gumargalieva
N. N. Semenov Institute of Chemical Physics, RAS, Moscow, Russia

A. N. Inozemtsev
M. V. Lomonosov MSU, Biological Faculty, Leninskie Gory, 119991, Moscow, Russia

V. V. Kasparov
Emanuel Institute of Biochemical Physics RAS, 119334, Moscow, Russia

Yu. A. Kim
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow, Russia

М. А. Klyuchnikova
A. N. Severtzov Institute of Ecology and Evolution, 33 Leninski prospect, Moscow, 119071, Russia; e-
mail: [email protected]

Sergei S. Kolesov
The Institute of Organic Chemistry of the Ufa Scientific Centre the Russian Academy of Science, Russia,
Republic of Bashkortostan, Ufa, 450054, October Prospect 71.

A. L. Kovarskij
Emanuel Institute of Biochemical Physics RAS, 119334, Moscow, Russia.

A. A. Kozlova
A. N. Severtsov Institute of Ecology and Evolution, RAS, 33 Leninskij prosp., Moscow, 119071, Russia.

L. Z. Кrаvtsovа
The “NTС BIO”, LLC, 309292, Russia, Belgorod Region, Shebekino town, e-mail: [email protected]

E. I. Kulish
Bashkir State University, Russia, Republic of Bashkortostan, Ufa, 450074, ul. Zaki Validi.

S. V. Kvach
Institute of Microbiology, National Academy of Sciences, 220141, Minsk, Belarus.

С. А. Liman
the “Аgroakademia”, LLC, 309290 Russia, Belgorod region, Shebekino town, А., e-mail: agroaka-
[email protected]

Murygina Lomonosov
Moscow State University, Chemistry Faculty, Department of Chemical Enzymology. 119991, Moscow,
Leninsky gory 1/11

Debarshi Kar Mahapatra

School of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur,
Chattisgarh, India

T. V. Malanina
A.N.Severtzov Institute of Ecology & Evolution, 33 Leninski prospect, Moscow, 119071, Russia, email:
[email protected].
E. I. Martirosova
Emanuel Institute of Biochemical Physics, RAS, 119334, Moscow, Russia. Email: [email protected]
List of Contributors xiii

O. V. Nevrova
Emanuel Institute of Biochemical Physics RAS, 119334, Moscow, Russia

I. R. Oviya
Department of Bioinformatics, Bharathiar University, Coimbatore, India.

Yu. D. Pakhomov
FGBU “I.I. Mechnikov Research Institute for Vaccines and Sera” RAMS., Moscow 105064 Maliy Ka-
zenniy per. 5a. e-mail [email protected].

D. S. Pavlov
A.N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, 119071 Russia, Mos-
cow.

I. G. Plashchina
Emanuel Institute of Biochemical Physics, RAS, 119334, Moscow, Russia.

V. V. Podmasteryev
N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 119334, Moscow, Russia

S. V. Ponomarev
the “Bioaquapark” Innovation Centre– The Scientific Centre of the Aqua-Culture at the АSTU, 414025,
Astrakhan, e-mail: [email protected]

V. G. Pravdin
The “NTС BIO”, LLC, 309292, Russia, Belgorod region, Shebekino town, e-mail: [email protected]

S. D. Razumovsky
N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Mascow, Russia.

Е. I. Rodionova
A. A. Kharkevich Institute for Information Transmission, 19 B. Karetny, Moscow, 127994, Russia.

E. G. Rozantsev
Saratov State University named after N.G. Chernyshevsky, Russia.

A. S. Samsonova
Institute of Microbiology, National Academy of Sciences, Belarus, 220141, Minsk, Belarus

R. Sathishkumar
Dept. of Biotechnology, Salem Sowdeswari College, Salem, India.

I. P. Savchenkova
All Russian State Research Institute of Experimental Veterinary Medicine of Ya.R. Kovalenko, 109428,
Russia, Moscow, E–mail: [email protected]

S. V. Sazonov
GBUZSO Institute of Medical Cell Technologies, 620036 Yekaterinburg.

T. P. Shakun
Institute of Microbiology, National Academy of Sciences, Belarus, 220141, Minsk, Belarus, E-mail:
[email protected].

M. Sharanya
Department of Bioinformatics, Bharathiar University, Coimbatore, India.
Angela S. Shurshina
Bashkir State University, Russia, Republic of Bashkortostan, Ufa, 450074.
xiv List of Contributors

V. S. Sibirtsev
GiproRjibFlot (Research and design institute on development and exploitation of a fish fleet), lab. Tech-
nical microbiology; Instrumentalnaja ul. 8, 197022 Russia, e-mail: [email protected]; site: http:\\www.
vs1969r.narod.ru\publen.htm

Anamika Singh
Maitreyi Collage, University of Delhi, India. E-mail: [email protected]
Rajeev Singh
Division of Reproductive and Child Health, Indian Council of Medical Research, New Delhi

G. G. Sivets
Institute of Bioorganic Chemistry, National Academy of Sciences, 220141, Minsk, Belarus

N. N. Skorlupkina
FGBU “I. I. Mechnikov Research Institute for Vaccines and Sera” RAMS., Moscow 105064 Maliy Ka-
zenniy per. 5a. e-mail [email protected] tel.: +7 495 916-11-52, fax: +7 495 917-54-60.

N. А. Ushakova
A. N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, 33 Leninskij prosp.,
Moscow, 119071 Russia, fax (8495) 954-55-34, e-mail [email protected]

P. Valentina
Moscow State University, Chemistry Faculty, Department of Chemical Enzymology, 119991, Moscow,
Russia.

A. E. Voznesenskaya
A. A. Kharkevich Institute for Information Transmission, 127994, Moscow, Russia

V. V. Voznessenskaya
A. N. Severtzov Institute of Ecology & Evolution, 33 Leninski prospect, Moscow, 119071, Russia,
Email: [email protected].

Bataeva Yulia
Federal State Budget Educational Institution of Higher Professional Education, Astrakhan State Univer-
sity. E-mail: [email protected]

A. A. Zagorinsky
A. N. Severtsov Institute of Ecology and Evolution, RAS, 33 Leninskij prosp., Moscow, 119071, Russia.

G. E. Zaikov
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow 119334,
Russia, [email protected]

Y. M. Zasadkevich
GBUZSO Institute of Medical Cell Technologies, 620036 Yekaterinburg, Russia.

A. I. Zinchenko
Institute of Microbiology, National Academy of Sciences, 220141, Minsk, Belarus.
LIST OF ABBREVIATIONS

AD Alzheimer's disease
AFO ankle foot orthotics
AHB alkylhydroxybenzenes
AMS amikacin sulfate
AMS antibiotics - amikacin
BSA bovine serum albumin
CBC cyano-bacterial communities
CBT cognitive behavioral therapy
ChTA chitosan acetate
CMC critical micelle concentration
CTD common technical document
EMEA evaluation of medicinal products
EPR electron paramagnetic resonance
ETP electron transport particles
FFA free fatty acids
FSR fragmented sarcoplasmic reticulum
HAS human serum albumin
INNs international non-proprietary names
LMWC low molecular weight chitosans
LT longitudinal tubules
MFC minimal fungicidal concentration
MFD minimum fungicidal dilution
MIC minimal inhibitory concentration
MID minimum inhibitory dilution
NMR nuclear magnetic resonance
PD Parkinson's disease
PRCA pure red cell aplasia
PRET progressive resisted exercise training
RyR ryanodine receptor
SIRS system inflammatory response syndrome
SR sarcoplasmic reticulum
TC terminal cysternaes
TCM traditional chinese medicine
TGA therapeutic goods administration
UPSIT University of Pennsylvania Smell Identification Test
LIST OF SYMBOLS

m∞ relative amount of water in equilibrium swelling film sample

k constant connected with parameters of interaction polymer
n indicator characterizing the mechanism
c0 surface concentration
τ constant of proportionality
τс rotational diffusion correlation time
V volume of the radical
η dynamic viscosity of the medium
K Boltzmann constant
T absolute temperature
n number of cracks
l length of a crack
h depth
D optical density
α solubility coefficient
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