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THREE DAUGHTERS
THREE JOURNEYS
Pan Stanford Series on Renewable Energy — Volume 2

THREE DAUGHTERS
THREE JOURNEYS
Quest for Cancer Cure

Ananda M. Chakrabarty
editors Jill Charles
Preben Maegaard Indrani Mondal
Anna Krenz
Wolfgang Palz Ranjita Chattopadhyay

The Rise of Modern Wind Energy

Wind Power
for the World
Published by

Pan Stanford Publishing Pte. Ltd.

Penthouse Level, Suntec Tower 3
8 Temasek Boulevard
Singapore 038988

Email: [email protected]
Web: www.panstanford.com

British Library Cataloguing-in-Publication Data

A catalogue record for this book is available from the British Library.

Three Daughters, Three Journeys: Quest for Cancer Cure

Copyright © 2017 Pan Stanford Publishing Pte. Ltd.

All rights reserved. This book, or parts thereof, may not be reproduced in any
form or by any means, electronic or mechanical, including photocopying,
recording or any information storage and retrieval system now known or to be
invented, without written permission from the publisher.

For photocopying of material in this volume, please pay a copying fee

through the Copyright Clearance Center, Inc., 222 Rosewood Drive,
Danvers, MA 01923, USA. In this case permission to photocopy is not
required from the publisher.

The characters and events in this book are fictitious. Any similarity to
real persons, living or dead, is coincidental and not intended by the
author.

ISBN 978-981-4745-90-1 (Hardcover)

ISBN 978-1-315-19666-4 (eBook)

Printed in the USA

 Contents

Preface vii

1 Selena – Sunflowers 1
2 Marzena – Daybreak 13
3 Kamola – Murmur of the River 21
4 Selena – The Test 27
5 Marzena – Day 37
6 Kamola – The Magic World 43
7 Selena – Why Right Now? 47
8 Marzena – Twilight 59
9 Kamola – The Big Yellow Moon 65
10 Selena – Knowing the Worst 71
11 Marzena – Night 81
12 Kamola – The Milk Tea and Sterile Bed 89
13 Selena – No Hard Feelings 93
14 Marzena – New Dawn 99
15 Kamola – Light at the End of the Tunnel 103
16 Selena – Sunflower House 113
17 Kamola – The Sunshine 129
vi Contents

18 The Quest Begins 135

19 The Conference 143
20 Three Daughters 161

Index 167
 Preface

Cancer is a dreaded disease worldwide with countless

victims. Although cancers in different organs may have
different etiologies, essentially all cancers are due to
mutations in our genome, anywhere in a few to 100
different genes. The mutations could be due to lifestyle
choice or simply due to bad luck. Several such mutations
have been found in two genes known as BRCA1 and
BRCA2 genes, occurring in two different chromosomes
in our bodies, which may lead to the development of
breast or ovarian cancer in women at a much higher
frequency than normal. Inheritance of such BRCA1 and/
or BRCA2 gene mutations from the parents can therefore
lead to breast or ovarian cancer in women with family
history of such cancers at a much higher rate, thereby
causing alarm in young women with such a family
history. This book is a fiction based on three young girls
with family histories of breast or ovarian cancer who
were diagnosed to harbor the harmful mutations. The
three young girls, living on three different continents,
however, pursued three different avenues for their
therapy, which is the focus of this book. Although the
paths followed by the second and third daughters are
fictional at this time, the book discusses the future
potential of the development of such therapies for
viii Preface

cancer, as reflected during the conversations of the

physicians, to provide some glimpse of how the future
therapy of cancer might take shape. The authors would
love to hear our readers’ thoughts and concerns about
the message, fictional as it is, implied in this book. The
stories of the three daughters have been penned by
Jill Charles (“Story of Selena”), Indrani Mondal (“Story
of Marzena”) and Ranjita Chattopadhyay (“Story of
Kamola”), with Jill Charles writing up the concluding
sections (Chapters 19 and 20) and editing the book.

Ananda M. Chakrabarty
 1

SELENA

Sunflowers

Selena always remembered her mother’s sunflowers.

Nine feet tall, bowing their golden heads toward the
lawn, with yellow goldfinches hiding in their green
leaves, nipping their striped seeds. In her earliest
memory, Selena toddled over to the giant plants, tried
to climb them, and cried when the thick fuzzy stems
bent and broke under her weight. These flowers stood
taller than she was, taller than Mama, even taller than
Daddy, a long lean man people often mistook for a
basketball player.
When Selena couldn’t climb the sunflowers, her
mama and daddy lifted her up on their shoulders so she
could stroke the soft yellow petals. Later they taught her
how to crack the seeds in her teeth and spit the shells.

Three Daughters, Three Journeys: Quest for Cancer Cure

Ananda M. Chakrabarty, Jill Charles, Indrani Mondal,
and Ranjita Chattopadhyay
Copyright © 2017 Pan Stanford Publishing Pte. Ltd.
ISBN 978-981-4745-90-1 (Hardcover), 978-1-315-19666-4 (eBook)
www.panstanford.com
2 Three Daughters, Three Journeys

The brown and gold of the sunflowers reminded Selena

of her mama’s soft brown skin and the gold she liked to
wear in earrings, necklaces and tiny rings at the ends of
her long black braids. The height of the flowers and the
way they swayed in the Chicago wind reminded her of
Daddy playing blues guitar, at home or at his club, the
Blue Jay.
The Blue Jay had three floors with DJs, a 24-hour
restaurant, two bars, a dance club and a concert
hall. Selena would run around after Daddy, tapping
the cymbals or dancing to the piano while the bands
tuned up. She could look out the club windows and
see Lake Michigan, Chicago’s skyline with the Sears
Tower, Hancock Building and the El train tracks of the
South Loop. Daddy pointed out Union Station, where
he had arrived in town years ago on a train from New
Orleans, with only a steel guitar, harmonica, and
backpack full of twenty-year-old dreams. He’d played
in eight bands—blues, jazz and rock—and worked his
way up to managing a club, managing an apartment,
then buying a South side bar, then an apartment
complex. He and Mama bought an old Bronzeville
mansion and remodeled it, like a gray stone palace.
Daddy called Selena “Princess” and her mother
“Queen Bea.” Unlike her husband Jack Ramos, Beatrice
Wells Ramos came from a well-to-do black family that
had lived in Bronzeville since the 1940s. She was the
third generation in her family to go to college, in a long
line of preachers, teachers, businessmen and doctors.
Beatrice was majoring in history at the University of
Chicago when she met Jack. She saw him playing Walking
Blues in a dark, smoky club and fell completely in love
with him. He looked out into the audience and spotted
 Sunflowers 3

her, with her gold-tipped braids and a black-eyed Susan

flower behind her ear, and he fell in love with Bea too.
They danced together before they spoke, then talked
all night, just the beginning of a conversation that
would last a lifetime. They married right after Beatrice
graduated and Selena came along two years later.
Selena always wished for a sibling, but her busy
parents struggled to make time for one daughter as her
mother taught women’s studies and Black history and
competed hard for tenure. Her dad invested more in
real estate and hired new musical acts and DJs at the
Blue Jay every month. Selena felt lucky when she saw
how her parents stretched their schedules, to make sure
at least one of them shared breakfast with her, cooking
her favorite soft-boiled egg and oatmeal. At least one of
them would pick her up from school every day and help
her with long division and Spanish verbs. Daddy would
get up with Selena after being up till 3 a.m. playing
blues when a musician called in sick to the club. Mama
would pile her history books, some of which she wrote,
on the kitchen table with Selena’s. They drank mint tea
while they did homework together.
To keep Selena company, her parents always let
her have pets: two cockatiels named Billie and Buddy,
a fluffy black chinchilla named Coco and a huge
aquarium of angelfish, mollies and tetras, each of
whom Selena had named and fed and cleaned up after
every day. Selena tried to take care of her pets like her
parents took care of her. At age ten she was allowed to
adopt a dog and chose a rescued black Greyhound, free
to a good home, who she named Jojo. Jojo loved Selena
so much she’d wait inside the garden gate for her to
come home from school even when snow covered their
4 Three Daughters, Three Journeys

garden. Selena loved to take the Green Line El train

home from her selective enrollment public high school
and see Jojo waiting to play in the yard and walk around
their neighborhood.
Selena made friends eagerly with all kinds of chil-
dren: girls, boys, outspoken class clowns, shy bookish
kids who rarely spoke except to her, basketball stars,
cheerleaders and a deaf girl who made rap videos in
sign language. Since kindergarten, Selena had kept the
same best friend, Janine Jones, a plump girl with skin
the color of chocolate milk and big glasses who loved to
draw cartoons and even made a comic book version of
their lives. Selena wanted to become blood sisters, but
Janine dreaded needles and would have none of it.
“We’re sisters in our souls. That’s all we need,” Janine
said.
Life was laughter, love and adventure, just like
Janine’s comics, until Selena’s seventeenth Christmas.
Mama was in the kitchen putting the final glaze on a
ham crowned with pineapple rings and cloves. Aromas
of collard greens with smoked turkey, cornbread, sweet
potatoes and macaroni and cheese filled the house. Two
of Mama’s pies, sweet potato and pecan, cooled on the
counter. Daddy was picking up his mother, Grandma
Grace, at the airport. Their friends and the aunts, uncles
and cousins would all be over soon. Janine had arrived
first and was helping Selena set the table with golden
napkins and red glass plates.
From the dining room, Selena heard her mother gasp
and something clatter to the kitchen floor. She rushed
in to help Mama.
“Mama, are you OK?”
 Sunflowers 5

Her mother leaned over the kitchen sink, clutching

the counter. She had dropped a wooden spoon and
Selena bent down to pick it up. Mama pressed a hand,
hard, into the left side of her belly, between her hipbone
and her navel.
She whispered, “I’m all right, baby. Just some
cramps.”
“Sit down for a minute,” Selena said. “I’ll get the
food ready.”
“No, no,” Mama insisted. “I’m all right.”
Janine and Selena carried all the heavy serving
dishes, wanting to help, but unable to convince Mama
to rest. Mama looked more tired than usual, even when
she hugged Grandma Grace and kissed Daddy, as she
welcomed all their friends and family to dinner. She
tried to hide her pain but Selena felt it.
A few nights after Christmas, Selena woke up to get
a drink of water. As she crossed the upstairs hall, she
heard her parents talking downstairs.
Daddy hugged Mama in the rainbow glow of their
Christmas tree lights.
“You take care of everybody, Queen Bea. It’s my job
to take care of you this time.”
“Jack, you know how I hate doctors.”
“I know. That’s why I made you an appointment with
Dr. Chandra Patel. She’s Dahlia Jones’s doctor and the
absolute best, plus being a U of Chicago graduate.”
“I think I had her in freshman history. Jack, I don’t
want to see someone younger than I, someone who
remembers me as a professor, not even if she’s your star
performer’s favorite doctor.”
“Then you can change doctors, Bea, but the appoint-
ment’s on Thursday and I’m going with you.”
6 Three Daughters, Three Journeys

“What about Selena?”

“Mom’s taking her shopping downtown all day. We
won’t need to worry her with any of this until we get
the test results. It could be nothing, but you have to be
checked.”
“I’ll see Dr. Patel.”
Too scared to confront her parents, Selena lay down
in her bed and cried softly. Mama and Daddy seldom
disagreed strongly on anything. She could tell her
mother was scared, not angry, and she already suspected
why.
Selena turned eighteen in January. A week after-
ward, she sat in the living room drinking tea with her
mother. She had convinced herself that whatever tests
her mother had must have come back negative and
been forgotten. Then, instead of asking her what her
homework was, Mama said, “Have tea and talk with
me.”
Sensing that this would be a serious talk, she settled
beside her mother on the couch.
“Selena, you know I’ve been seeing Dr. Patel.”
“Yes.”
“I’ve been having abdominal pain for a few months
and your dad thought I should get it checked out.”
“Right.”
Selena set her teacup down. Her voice sounded small
and her face felt hot.
“Dr. Patel wanted to be certain about my symptoms
and the cause. I had an ultrasound, an MRI and a
biopsy.”
Selena held Mama’s hand, something she hadn’t
done since grade school. Her mother looked down, then
looked Selena in the eye.
 Sunflowers 7

“Selena, I have cancer. There are two tumors, in my

left ovary and in my left breast. It’s stage III and it has
metastasized.”
“What?”
“That means the cancer is in my lymph nodes and
has spread to more than one part of my body. I’ll have a
double mastectomy and have both my ovaries removed,
then have chemotherapy and radiation. Treatment will
be hard, but I know I can count on Daddy and you to
help me.”
“Of course, but why do you have to have both
breasts and both ovaries taken out if only one of each is
cancerous?”
Mama let go of Selena’s hand and sipped her tea.
“This type of cancer has a genetic element. It’s caused
by two genetic mutations on the BRCA1 and BRCA2
genes. I tested positive for both mutations. Women who
have one or both are very likely to get breast or ovarian
cancer. I got a second opinion from another doctor,
and she agreed it’s safest for me to have both breasts
and both ovaries removed to minimize the risk of more
tumors.”
“Mama, does anyone else in our family have this?”
“No one else in our family has been tested, but you
know we lost Grandma Lily to breast cancer when you
were four.”
Selena nodded. She had a few happy memories of
Mama’s mother holding her, singing and reading to her.
“If it’s genetic, will I have it?”
Mama covered her face with her hands and burst
into tears. Selena hugged her, scared and miserable. She
had never seen her mother cry.
“Mama, I’m so sorry. What can I do to help?”
8 Three Daughters, Three Journeys

Both of them cried softly now.

“Stick with your schoolwork. Stick with your college
applications.”
“I’m not going away to Spellman or Stanford. I’ll go
to the University of Chicago.”
“I don’t want you missing out on anything for me. I
especially don’t want you to drink or smoke or try drugs
to kill the pain. This will be bad, but it won’t be forever.
In one year, my chemo will be done.”
“I’m not leaving town, Mama. I can ace all my classes,
but I’m not leaving you for one minute. I can help drive
you to your appointments. I can cook and clean house.”
“Shh. I don’t want you missing school for me. Though
I have to say I’m thrilled that you offered to clean up.
You always help Daddy and me, and Grandma Grace
will come to live with us for a while. We’ll get through
this, Selena. Tomorrow we can go out and buy me a wig,
maybe a purple one.”
Selena tried to laugh.
It hurt to see her mother walking slowly, hurt to
find her asleep, exhausted on the couch after chemo.
Sometimes Selena could barely wake Mama up with
shaking and shouting, which terrified her. It shocked
her to see Mama take off her wig (natural black braids
tipped with gold, not punk purple) and scratch her bare
scalp, then wrap a cotton scarf around her head.
Mama rarely complained about anything, though
Daddy, Selena and Grandma Grace saw how she
suffered. They rushed to help her so much that Mama
protested, “Stop fussing over me.”
“Daddy, I’m so scared for her,” Selena confided.
Daddy hugged her and said, “Me too, Princess. But
she’s a fighter. And Dr. Patel is the best oncologist in
 Sunflowers 9

town, one of the best in the country. We’ll get through

this. I’m so proud of you looking after Mama. You’re a
real adult now.”
Adulthood meant more than the independence
Selena always hoped for; it meant loss and pain and
never, ever taking love for granted again.
Having Grandma Grace move into their biggest guest
room was the only positive aspect of Mama’s cancer.
Grandma Grace helped with everything at home. She
drove Mama to and from appointments or stayed with
Selena while Daddy took Mama to chemo. Daddy would
have to carry her upstairs and tuck her into bed, like a
baby.
Selena prayed harder than she’d ever prayed before.
She promised God she would be perfect in mind, word
and deed if only Mama could survive. She remembered
all the times she’d been rude to Mama or ignored her
or wanted to go out with Janine and her friends instead
of staying home with her family. Now Selena felt she
could never have enough time with her mother. Had
she ever thanked God for giving her such a good mother
who loved her and took care of her every day? Although
Selena always loved her mother, she realized she had
never thanked God for her. Like children often do, she
took her parents’ love for granted and never even tried
to imagine her life without it.
“Thank you for giving me a good mother,” Selena
prayed. “I will help her no matter what, Lord. I will
make her proud of me. I’ll be brave and wise and kind,
like she is and use everything I learn to help others
too. Please make me like Mama. Please let me keep my
Mama.”
10 Three Daughters, Three Journeys

Mama came to Selena’s high school graduation,

though she leaned heavily on Daddy and had to walk
with a cane. That summer she went to stay at the
hospital. The cancer had spread and entered stage IV
with tumors in her liver and her right lung. Dr. Patel
estimated that Mama had six months. She was too sick
to go home, though Daddy could have afforded a full-
time nurse and Grandma Grace was more than willing
to be a full-time caregiver. Mama chose not to continue
chemo and to move into a hospice, to receive palliative
care and visits from all her family and friends, from
many of her students. Daddy played his guitar softly in
her room and sang the blues to her. Grandma Grace and
Selena visited her every day with all the news of school,
the university, church and their neighbors. Selena read
Mama her college term papers. The painkillers clouded
Mama’s energy, but she was still there.
In October, Selena visited Mama in the hospital,
showing her pictures of the University of Chicago dorm
room she and Janine had decorated with plants and
posters.
“You’re doing so well,” Mama whispered. “I’m so
proud of you. I love you, honey.”
Selena set her hand on her mother’s, but couldn’t
hold it because of the IV.
“Mama, please come home.”
“Selena, you know I can’t. I don’t want any room in
our house to be the room where I passed, and for you
and Daddy and Grandma to have to walk past it every
day. I want all your memories of home to be good
memories.”
“Every memory with you is a good memory. Mama,
please don’t leave me.”
 Sunflowers 11

“I’ll never leave you, Selena. I am with you. I am

in you, no matter what you do or where you go. Me
and Daddy and your grandparents, we are part of you
and our love will always be there. Never doubt God’s
love and never doubt mine. Promise me, you’ll always
remember that.”
“I promise. Mama, why did this happen?”
“I don’t know why this happens. No one deserves
this, no one and we just have to love each other and help
each other. It’s OK to cry and to doubt and to be angry,
but know you are never alone, Selena. Remember.”
Beside Mama’s bed, the setting sun shone on a green
glass vase of sunflowers from her garden.
Selena’s Mama died in November, just before Thanks-
giving.
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