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Prelims.qxd 9/15/04 6:14 AM Page i
                                     Pediatric Ultrasound
Prelims.qxd 9/15/04 6:14 AM Page ii
         For Elsevier:
         Senior Commissioning Editor: Sarena Wolfaard
         Project Development Manager: Mairi McCubbin
         Project Manager: Derek Robertson
         Designer: Judith Wright
         Illustrations Manager: Bruce Hogarth
Prelims.qxd 9/15/04 6:14 AM Page iii
            Pediatric Ultrasound
            How, Why and When
            E D I N B U R G H L O N D O N N E W YO R K O X F O R D P H I L A D E L P H I A S T L O U I S S Y D N E Y T O R O N T O   2005
Prelims.qxd 9/15/04 6:14 AM Page iv
        CHURCHILL LIVINGSTONE
        An imprint of Elsevier Limited
        The right of Rose de Bruyn to be identified as author of this work has been asserted by her in
        accordance with the Copyright, Designs and Patents Act 1988.
        No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form
        or by any means, electronic, mechanical, photocopying, recording or otherwise, without either the prior
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Prelims.qxd 9/15/04 6:14 AM Page v
Contents
vii
Contributors
ix
Preface
         Ultrasound is one of the most widely used imaging       system, together with a fundamental clinical ultra-
         modalities in pediatric radiology and is set to con-    sound training. The intention is to provide an
         tinue to grow and develop as computing and              approach to ultrasound examinations and to
         equipment improves and new applications become          emphasize the real value of ultrasound and its place
         available. Children are ideally suited to ultrasound,   in the broader perspective of the imaging modali-
         since their low levels of body fat contribute to        ties available.
         ultrasound images of exquisite detail.                     Clinical expectations of the diagnostic ability of
             This book is intended as a practical starting       ultrasound are exceedingly high in pediatrics. The
         point for radiologists, sonographers and other          sonographer must strive for a good understanding
         medical healthcare professionals undertaking ultra-     of what is achievable and for excellence in tech-
         sound examinations in children, providing all nec-      nique. Working with children can be one of the
         essary normative charts and guidelines on               most challenging and rewarding experiences.
         examining techniques. The book is not a compre-            The author gratefully acknowledges the help,
         hensive text on all the many different pathologies      stimulation and advice of all her colleagues and
         likely to be encountered in children, but it is         sonographers in the ultrasound department at
         intended to highlight the strengths and weaknesses      Great Ormond Street Hospital for Children NHS
         of ultrasound in the important conditions. The aim      Trust. Also thanks to Michelle Le Maire for her
         is to provide the sonographer with a framework to       patience, encouragement and invaluable help in
         use in diagnosis, so that the maximum amount of         preparing the manuscript. This book is for all the
         information can be gained from the ultrasound.          sick children.
             It is assumed that the sonographer has a basic                                                    R.d.B.
         understanding of how to operate an ultrasound                                                 London, 2005
Prelims.qxd 9/15/04 6:14 AM Page x
Chapter 1
2 PEDIATRIC ULTRASOUND
          can be addressed and the answers can put the par-         ●   demonstrate dilated lower ureters, which other-
          ents’ minds at rest. A contact telephone number               wise may be missed
          on the leaflet is also useful in case the parents have    ●   perform a pre- and post-micturition view which
          any other concerns and want to speak to a member              is standard for all.
          of the ultrasound team.
             The appointment letter should clearly state:               Infants who are to undergo examinations of the
                                                                    gallbladder and biliary tree should be fasted so that
          ●    the appointment date                                 they are scanned just before their next feed, after a
          ●    the time of the scan (including the time at which    3–4-hour fast. Children should be booked first
               the patient should arrive in the department, which   thing in the morning after an overnight fast, other-
               may be some time before the scan takes place)        wise a minimum 6-hour fast is required.
          ●    which examination has been booked                        All children who undergo pelvic examinations
          ●    the department in which the scan will take place.    should have a full bladder when scanned.
                                                                        Endovaginal and endorectal scanning are not
                                                                    practiced routinely in children.
          Preparation
                                                                        If a child is to have multiple examinations it is
          Specific preparation for different scans should be        best to make ultrasound the first examination.
          worded simply but clearly. Examples are as follows.       Cystography requires bladder catheterization which
                                                                    is invasive and may render the child upset and cry-
          ●    For ultrasound scans of the gallbladder/liver—
                                                                    ing during a later ultrasound examination. Also,
               ‘Please ensure that your son/daughter does not
                                                                    studies involving nuclear medicine or intravenous
               have anything to eat or drink for at least 4–6
                                                                    urography generally require an injection, which
               hours before the scan appointment time. If your
                                                                    may also upset the child and make him or her anx-
               child is a baby then the scan should be timed for
                                                                    ious and less cooperative for a later scan. After the
               just before a feed.’
                                                                    injection of a radioisotope the child will also be
          ●    For renal ultrasounds—‘Please ensure that your
                                                                    radioactive. Admittedly the dose is small, but this is
               son/daughter arrives in the department with a
                                                                    an unnecessary radiation exposure for the sonogra-
               FULL BLADDER. If your child is still in nap-
                                                                    pher. In addition, if a young child voids radioactive
               pies, please ensure that they have a bottle of
                                                                    urine while being examined, the ultrasound exam-
               milk or clear fluid prior to the examination.’
                                                                    ining couch and equipment may become contami-
          ●    For pelvic/ovarian ultrasound scans
                                                                    nated, delaying further examinations.
               —‘Please ensure that your son/daughter arrives
               in the department with a FULL BLADDER. If
               your child is still in nappies, please ensure that   THE WAITING AREA
               they have a bottle of milk or clear fluid prior to
                                                                    This is one of the most important areas of the
               the examination.’
                                                                    department, and every age range should be catered
               —‘If your son/daughter is aged 6–11 years they
                                                                    for. There should be soft play areas for the infants,
               should drink at least 1 pint of water 1 hour prior
                                                                    interesting activities for the children and a games
               to the appointment time.’
                                                                    area for the adolescents. A well-designed space
               —‘If your son/daughter is aged 12–16 years
                                                                    where the child can wait and be entertained hap-
               they should drink at least 1 1/2 pints of water
                                                                    pily is essential (Fig. 1.1). The availability of Play
               1 hour prior to the appointment time.’
                                                                    Specialists, who can explain the examination to the
          ●    ‘This examination involves the use of a sound
                                                                    child in a simple way with toys, is extremely help-
               beam to form pictures of some of the organs
                                                                    ful. Don’t forget that parents are often very anx-
               within the body to help your doctor. The exami-
                                                                    ious about the impending examination, and if the
               nation normally takes about 30 minutes and
                                                                    child is bored and unhappy then stress levels will
               does not hurt.’
                                                                    rise and often boil over into anger which may be
            All renal tract examinations should be on a well-       directed at you the sonographer. Always try to per-
          hydrated child with a full bladder so as to:              form the examination on time and do not keep a
Ch01.qxd 9/14/04 5:26 PM Page 3
GENERAL ISSUES 3
A B
         C                                                                D
         Figure 1.1 Examples of play areas. (A) A well-designed waiting area is an important part of any department
         undertaking investigations on children. This is an interactive area of the department for young children where they can
         draw, paint and play with many different types of toys. There are books available on the wall with mobiles on the
         ceiling. A play specialist to explain the examinations to children in a friendly and gentle way helps alleviate anxiety
         and fear. The area is light and welcoming with familiar objects. (B) Interactive areas are particularly good to keep
         children entertained. This space station is designed for children with special needs so that they are attracted by lights
         and water features. The tail of the space station allows access for children in wheelchairs. (C) All age ranges should be
         catered for. This is a soft play area for babies where they can fall and not be hurt. (D) This is an area designated for
         older children. There is a television, a playstation, books and activities for the older child.
4 PEDIATRIC ULTRASOUND
GENERAL ISSUES 5
         to ensure that they are fed just prior to the ultra-   ●   the age range of the patients to be scanned—
         sound so that they are quiet and sleepy.                   from babies to adolescents (i.e. adult size)
            If children are reluctant to be scanned while       ●   the intended workload and types of examina-
         lying supine, be adventurous and accommodating             tions to be undertaken—for example, abdomi-
         for the scanning position (Fig. 1.3). Sit them on          nal, cranial, musculoskeletal or interventional.
         mother’s lap, get her to lie down on the couch
                                                                  The biggest mistake made when choosing
         with the child on her tummy, but don’t give up
                                                                equipment is generally to provide too few trans-
         without a good attempt. Children do not need to
                                                                ducers to be able to scan this very wide age range
         be undressed; removing clothes makes them
                                                                and undertake the variety of types of examination.
         unhappy and vulnerable. Usually all that is
                                                                Often equipment is bought for both adult and
         required is to pull up tops and undo trousers or
                                                                pediatric use and a high quality machine is pur-
         lower garments.
                                                                chased with an insufficient number of transducers.
            Certificates and/or stickers to mark a successful
                                                                This is false economy, and it would be better to
         examination are generally important rewards.
                                                                buy a cheaper machine.
         Box 1.1 provides a summary of some aspects of
         good practice in carrying out examinations.
                                                                Probes
         CHOOSING EQUIPMENT
                                                                The commonest ultrasound examination in chil-
         When choosing a machine for dedicated pediatric        dren is the abdominal scan, so once again a good
         use, the following aspects of the service need to be   range of transducers is needed. Curved arrays are
         considered:                                            undoubtedly best and should be in a frequency
                                                                range suitable for newborns to adolescents, i.e. 7.5
           Box 1.1    The Optimum Pediatric Examination         to 3.5 MHz. A minimum of two probes is required
                                                                (Fig. 1.4).
           ●   Ensure the examination request form                 For neck, eye, musculoskeletal, and soft tissue
               contains sufficient information for you to be    lumps and bumps, a high frequency linear trans-
               able to perform an adequate scan                 ducer is needed such as a 15L8. This is an often
           ●   Before starting the examination decide what      neglected but essential probe. Cranial scanning can
               you hope to achieve from the scan. Know          generally be performed using a curved array but
               what you are looking for and review the          sometimes, when the fontanelle is small and access
               reports and/or any prior examinations            limited, the preference is for a small footprint vec-
               beforehand                                       tor transducer to enable better intracranial views
           ●   Use the correct transducers                      through the anterior fontanelle. For ocular scan-
           ●   Perform the examination quickly. Younger         ning a small footprint, high frequency probe is
               children only give you a small window of         required.
               opportunity and goodwill
           ●   Call someone to help sooner rather than later
           ●   Rarely, if ever, do children need to be          Machine capabilities
               sedated. Have adequate toys available for
                                                                The first requirement of the equipment must be to
               distraction and get parents to help
                                                                produce ultrasound images safely and of the high-
               immobilize the child
                                                                est quality. Generally it is false economy to invest in
           ●   Always perform a full and thorough
                                                                a cheap machine for pediatrics, as the image qual-
               examination in children. Never just look at a
                                                                ity, transducer availability and Doppler sensitivity is
               single system, e.g. renal tract. Congenital
                                                                inferior. The following are features to look for in a
               anomalies often involve multiple systems.
                                                                piece of equipment for pediatric scanning, where
               Pathology is missed because it is not looked
                                                                the patient is often a moving target and the sono-
               for
                                                                grapher has only a short period in which to do the
                                                                examination:
Ch01.qxd 9/14/04 5:27 PM Page 6
6 PEDIATRIC ULTRASOUND
A B
          C
Ch01.qxd 9/14/04 5:27 PM Page 7
GENERAL ISSUES 7
         ●   ergonomically sound, well-positioned and acces-           for example. Generally any delay in being able to
             sible function keys                                       perform a measurement prolongs the examina-
         ●   ease of use—programmable presets for the                  tion for the child. Caliper measurements are
             range of investigations help save time during the         best done by one hand. Measurement packages,
             examination and will also help produce images             for example hip angles, should be standard
             of diagnostic quality                                 ●   portability—examinations are often required in
         ●   probes—ability to connect several probes simul-           distant locations, and equipment needs to be
             taneously, or an easy switching mechanism;                readily portable and small enough to fit into
             change of seating position to enable probe                intensive care and bedside scenarios. Machines
             transfer is not desirable                                 used for portable examinations should be
         ●   patient data—patient name and date of exami-              lightweight and robust with moveable monitors
             nation should be standard                                 and control panels
         ●   variable focus and number of focal zones              ●   DICOM compliance—new equipment should
         ●   freeze frame with excellent static image quality          now all be compliant with Digital Image
         ●   cine replay—essential for moving children;                Communications in Medicine standards
             assess length and ease of replay                      ●   a good relationship with the manufacturer—
         ●   magnification and zoom facility—essential for             essential for a reliable 24-hour service and on-
             small structures; assess ease of use                      site maintenance. New equipment should ideally
         ●   labeling—this needs to be achieved quickly;               have remote diagnostics.
             body markers are generally too time consuming
         ●   Doppler capability—pediatric vascular structures
                                                                   USE OF DOPPLER IN PEDIATRICS
             are small, and Doppler of the highest sensitivity
             is essential; programmable presets should be the      Doppler is an integral part of any ultrasound exami-
             norm                                                  nation in children. Nowadays equipment without
         ●   simultaneous color and pulse Doppler display—         the Doppler capability should not even be consid-
             ability to change quickly between color power         ered for routine pediatric practice. Likewise, the
             Doppler (color ‘Doppler energy’) and color            sonographer should expect to be using and be
             Doppler is extremely useful                           familiar with Doppler controls in most examina-
         ●   measuring capabilities—measuring is an essen-         tions (Box 1.2).
             tial part of pediatric practice; however, the pre-       Power Doppler (sometimes known as Doppler
             cision is less critical than in obstetric scanning,   energy) is extremely useful in children, as it gives a
                                                                   quick overview. Power Doppler recognizes moving
                                                                   red cells but gives no information as to whether
                                                                   flow is arterial or venous. It is not angle dependent
                                                                   and is very sensitive. If a child is very restless and
                                                                   agitated, making a conventional study difficult,
                                                                   turning to the power application may allow simple
                                                                   questions, such as the presence of blood flow to an
                                                                   area, to be answered very quickly. It also quickly
                                                                   provides a very useful sketch of the layout of blood
                                                                   vessels before using the color flow imaging.
                                                                      Peripheral vascular studies are often requested in
                                                                   children for suspected occlusion of vessels from
                                                                   catheters. When performing these studies it is
                                                                   always wise to start off with the vessel on the ‘good’
                                                                   side so as to standardize the controls and use the
         Figure 1.4 A good range of transducers is needed for      vessel as a reference. Comparison can then be made
         the wide range of pediatric examinations.                 with the limb suspected of having pathology.
Ch01.qxd 9/14/04 5:27 PM Page 8
8 PEDIATRIC ULTRASOUND
            ●   The examination needs to be quick—a                   ●   Doppler receiver gain should be set so that
                prolonged procedure results in a bored,                   noise is just visible in the background. Set it
                restless and unhappy child and an                         too low and flow will be missed
                unsuccessful examination                              ●   Identify a vessel with color Doppler and then
            ●   Have presets installed for all examinations to            place the correct size of gate for adequate
                help minimize use of the Doppler controls and             spectral sampling. The gate must be
                optimize the Doppler capabilities of the                  positioned in the center of flow parallel to the
                equipment                                                 vessel walls. Slow flow will be difficult to
            ●   When examining limbs, examine the normal                  detect if the gate is too large
                limb first so that the settings are optimized.        ●   Ensure the beam steering is optimally set for
                This is particularly important in neonates with           the angle of incidence. The angle should be
                suspected vascular occlusion and where                    < 60˚ for Doppler studies
                vessels are small                                     ●   Keep the color box size (width) to the
            ●   Use the correct transducer within the                     minimum. A large box will slow the frame rate
                appropriate frequency range to obtain                     unacceptably in children
                adequate penetration. The higher the                  ●   Reducing the pulse repetition frequency (PRF)
                frequency the higher the sensitivity. Using a             will increase sensitivity at the cost of reduced
                lower frequency will improve the frame rate if            frame rate
                too slow                                              ●   Adjust the baseline and sweep speed so that
            ●   Magnify the image                                         spectral information is optimally displayed
             There are a number of areas where Doppler            ●   The operator’s chair should be completely
          examinations are an essential part of the standard          adjustable so that the back-rest and chair height
          examination. For example, all examinations of the           can be altered. There should be lumbar support
          liver, biliary tree and portal system require a             and a foot rest.
          Doppler examination both to show the patency            ●   The examination couches need to be adjustable
          and direction of flow in the hepatic vasculature and        so that they can be raised or lowered. This is also
          to help differentiate normal anatomy in the porta           particularly useful for children in wheelchairs.
          hepatis. Doppler should always be used in renal         ●   Equipment should be ergonomically sound with
          transplantation, in particular in the immediate             an adjustable keypad. Elbows and wrists should
          post-transplantation period and when looking for            be relaxed and not in awkward positions for
          arteriovenous shunts in the kidney. Vascular                scanning.
          anomalies are common in children. In superficial        ●   Monitors should be on a swivel and be at eye
          skin hemangiomas Doppler can help to assess the             level with no light reflection or glare.
          caliber and flow in the vasculature and whether the     ●   Every effort must be made to schedule patients
          hemangioma is suitable for treatment with sclero-           appropriately so that examinations are per-
          sant or embolization.                                       formed adequately and not rushed. Sono-
                                                                      graphers should have frequent breaks during the
                                                                      scanning day.
          AVOIDANCE OF OCCUPATIONAL INJURY
          Repetitive strain injury is well recognized in sono-
                                                                  IMAGE RECORDING AND STORAGE
          graphers, and it is incumbent on all departments to
          provide a good working environment for staff.           There are many ways of storing images. The
          General principles include the following.               range of analogue devices includes thermal
Ch01.qxd 9/14/04 5:27 PM Page 9
GENERAL ISSUES 9
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