Fissure in Ano, Fistula in Ano, and Hemorrhoids – History, Examination,
Investigation, and Treatment
Feature Fissure in Ano Fistula in Ano Hemorrhoids
Main complaint Severe pain during Persistent or Painless bleeding
and after defecation intermittent during defecation
discharge (pus or
mucus) from
opening near anus
Pain Severe, sharp, Dull aching pain, Usually painless
tearing pain during worse before (pain only if
defecation that may discharge and thrombosed)
persist for hours relieved after it
Bleeding Bright red blood Minimal or absent Bright red blood
streaking the stool that drips after
or on tissue (not defecation or stains
mixed with stool) the toilet
Discharge Rare (unless Pus or mucus None (unless
infected fissure) discharge from infected or
external opening prolapsed
hemorrhoid
ulcerates)
Relation to Pain and bleeding Discharge Bleeding after
defecation with defecation independent of defecation, no pain
defecation
Associated Constipation and History of perianal Mucosal prolapse,
symptoms fear of defecation abscess, fever (if itching, mucus
active infection) discharge (if
internal
hemorrhoids
prolapse)
Systemic symptoms Usually none Fever and malaise if None
abscess present
Inspection Linear tear in External opening Prolapsed
posterior midline, with discharge, hemorrhoids or
sentinel tag if induration, fibrosis congested veins on
chronic straining
Palpation Very painful, DRE Palpable induration Soft swellings, may
often not tolerated or cord-like tract prolapse with
straining
Digital Rectal Exam Avoid in acute May reveal internal Internal
(DRE) fissure due to pain opening or tract hemorrhoids felt as
soft bulges
Investigations Mainly clinical Proctoscopy, Proctoscopy/
diagnosis. If chronic fistulography, MRI anoscopy to assess
or atypical, rule out pelvis (to define grade, CBC if
Crohn’s, TB, tract), EUA bleeding.
carcinoma. (examination under
anesthesia).
Treatment ✅ Conservative: ✅ Surgical: ✅ Conservative:
High-fiber diet, stool Fistulotomy Fiber, avoid
softeners, sitz baths, (simple), Seton straining, topical
topical placement (high agents.
GTN/diltiazem, fistula), ✅ Non-surgical:
topical anesthetic. advancement flap Rubber band
✅ Surgical: Lateral (complex cases). ligation,
internal ✅ Antibiotics for sclerotherapy,
sphincterotomy for abscess. infrared
chronic fissure. coagulation.
✅ Surgical:
Hemorrhoidectomy
for grade III–IV.