Current status of diagnosis,
treatment and control of
haemorrhagic septicaemia in
buffaloes and cows.
Definition
Haemorrhagic septicaemia is acute, fatal, septicaemic
disease caused by strain of Pasteurella multocida
belonging to the serogroups B commonly in buffaloes
and cattle and also in pigs and feral ruminants.
Buffaloes are generally more susceptible than cattle
and young animals are more prone to the disease
than adults.
DIAGNOSIS
CLINICAL DIAGNOSIS
based on
1. clinical signs
2. gross pathological lesions
3. consideration of relevant epidemiological
parameters
A buffalo calf clinically affected with HS
Buffalo having
Submandibular
swelling
Buffalo calf
unable to suckle
milk due to
mandibular
swelling
ROUTINE LABORATORY DIAGNOSIS
Routine laboratory diagnosis is by culture
and serology
Material for lab diagnosis usually consists of
blood or a long bone for bone marrow culture.
Pure cultures are obtained from contaminated
material by mouse inoculation and culture of
the mouse blood.
OTHER DIGNOSTIC TESTS
Includes additional serological, biochemical and
molecular techniques
DIFFERENTIAL DIAGNOSIS
1. INFECTIOUS DISEASE—Anthrax, Rinderpest,
Black quarter
2. NON INFECTIOUS DISEASE—Lightening,
Snakebites and Acute poisoning
3. Respiratory form of disease and Pasteurellosis
caused by serotypes other than groupB and E or
by Pasteurella haemolytica.
TREATEMENT
HS is primary bacterial disease and theoretically
could be effectively treated by wide range of
antibiotics currently available. However
treatment is constrained by a host of practical
consideration
CHEMOTHERAPY
Inj. Ceftiofur sodium@ 1mg/kg body Wight intramuscular
in 24 hours for 3-5days
Inj. Ceftrioxone alone or with
sulbactin@3g/dayintramuscular once in 24 hours for 3-
5days
Inj. Gentamicin@30-40ml intramuscular, repeat after 8
hours for 3-5days
PREVENTION AND CONTROL
PROPHYLACTIC MEASURES IN ENDEMIC COUNTRIES
1. VACCINATE ON A ROUTINE PROPHYLATIC BASIS
2. ESTABLISH A GOOD REPORTING SYSTEM
3. CREATE AWARENESS OF THE DISEASE AMONG
FARMERS
4. PREVENT MIXING OF ANIMALS FROM ENDEMIC AND
NONENDEMIC AREAS
PREVENTIVE MEASURES DURING AN OUTBREAK
1. CONTINUE VACCINATION PROGRAMS
2. ISOLATE AND TREAT ANIMALS SHOWING CLINICAL SIGNS
WITH A PARENTERAL BROAD-SPECTRUM ANTIBIOTIC
3. CHECK THE RECTAL TEMPERATURE OF ALL IMMEDIATE INCONTACT
ANIMALS IN THE HERD
4. SEARCH DAILY FOR SICK ANIMALS OR CARCASES OF DEAD
ANIMALS-
5. CONFINE HERDS AS MUCH AS POSSIBLE, AND PREVENT
MOVENT OF ANIMALS IN AND OUT OF DISEASED PREMISES
OR VILLAGES.
6. TAKE IMMEDIATE ACTION TO CARRY OUT
POSTMORTEM EXAMINATIONS AND MAKE A
TENTATIVE DIAGNOSIS.
7. DISPATCH SPECIMENS TO THE NEAREST
DIAGNOSTIC LABORATORY
8. DISPOSE OF CARCASES OF DEAD ANIMALS
PROPERLY
9. PROPERLY DISPOSE OF UNCONSUMED FODDER, BEDDING
etc FROM INFECTED PREMISES
10. CLOSELY MONITOR OR STOP RAIN-ASSOCIATED
ACTIVITIES
PREVENTION OF SPREAD ACROSS BORDERS
• ENSURE THAT THE ANIMALS ORIGINATE FROM A
REGION WHERE NO OUTBREAKS OF HS HAVE
OCCURRED FOR AMINIMUM PERIOD OF ONE YEAR
2. BLEED A RANDOM SAMPLE OF ANIMALS
3. TEST FOR THE PRESENCE OF ANTIBODY BY THE
INDIRECT HAEMAGGLUTINATION TEST OR BY ELISA
4. HOLD ANIMALS UNDER OBSERVATION FOR TWO TO
THREE WEEKS BEFORE TRANSPORT
5. QUARANTINE ANIMALS AFTER TRANSPORT TO THE
NEW LOCATION
6. VACCINATE ANIMALS FROM DISEASE-FREE
LOCATIONS IN ENDEMIC COUNTRIES