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KORTIKOSTEROID TOPIKAL - Koass Kulit & Kelamin Kelompok 17

This document discusses topical corticosteroids, including their indications, classifications, uses, and side effects. Topical corticosteroids are used for dermatoses responsive to topical corticosteroids and have palliative and suppressive effects rather than treating the underlying cause. They are classified based on their clinical potency from ultra high to low. More potent corticosteroids are used for chronic, thick conditions while milder ones are used for babies, acute cases, or thin skin. Prolonged or excessive use can cause side effects like atrophy, striae, telangiectasis, and infection.

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299 views11 pages

KORTIKOSTEROID TOPIKAL - Koass Kulit & Kelamin Kelompok 17

This document discusses topical corticosteroids, including their indications, classifications, uses, and side effects. Topical corticosteroids are used for dermatoses responsive to topical corticosteroids and have palliative and suppressive effects rather than treating the underlying cause. They are classified based on their clinical potency from ultra high to low. More potent corticosteroids are used for chronic, thick conditions while milder ones are used for babies, acute cases, or thin skin. Prolonged or excessive use can cause side effects like atrophy, striae, telangiectasis, and infection.

Uploaded by

Desya Billa
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Indikasi

 Untuk Dermatosis yang responsif dengan kortikosteroid topikal.

 Bersifar paliatif dan supresif terhadap penyakit kulit dan bukan untuk
penyakit kausal

 Sifatnya sebagai: anti inflamasi, anti alergi, anti pruritus, anti mitotik
dan vasokontriksi
Penggolongan kortikosteroid topikal

Potensi
Klinis

Ultra High High Moderate Low


Potency Potency Potency Potency
Gol I Gol II & III Gol IV & V Gol VI & VII
Pemakaian

 Bayi / Kulit tipis = Kortikosteroid Topikal Lemah (Low Potency)

 Akut = Kortikosteroid Topikal lemah (Low Potency)

 Subakut = Kortikosteroid Topikal potensi sedang (Moderate Potency)

 Kronis dan Tebal = Kortikosteroid Topikal potensi kuat (High-Ultra High Potency)
Ultra high potency

Golongan I (super poten)


Sediaan Nama Generik
Ointment, cream 0,05% Betamethason dipropionate
Ointment 0,05% Diflorason diacetate
Ointment, cream 0,05% Clobetasol propionate
Ointment, cream 0,05% Halobetasol propianate
High Potency

Golongan II (potensi tinggi) Golongan III (potensi tinggi)


Sediaan Nama Generik Sediaan Nama Generik
Ointment 0,1% Amcinonide Cream 0,05% Betamethason dipropionate
Ointment 0,05% Betamethason dirpoprionate Ointment 0,1% Betamethason Valerate
Ointment 0,1% Mometason fuorate Cream 0,05% Diflorasone diacetate
Ointment 0,05% diflorasone diacetate Ointment 0,01% Triamcinolone acetonide
Ointment, 0,01% Halcinonide Cream 0,25% desoximetasone
cream
Ointment, 0,25% desoximetasone
cream
Moderate Potency

Golongan IV (potensi medium) Golongan V (potensi medium)


Sediaan Nama Generik Sediaan Nama Generik
Ointment 0,25% Fluocinolon acetonide Lotion 0,05% Betamethason dipropionate
Ointment 0,2% Hidrokortison Valerate Cream 0,1% Betamethason Valerate
Cream, 0,1% Mometason fuorate Cream 0,025% Fluosinolon acetonide
Lotion Lotion 0,01% Triamcinolone acetonide
Ointment, 0,1% Triamcinolone acetonide
Cream
Low Potency

Golongan VI (potensi medium-lemah) Golongan VII (potensi lemah)


Sediaan Nama Generik Obat topikal dengan
Lotion 0,05% Betamethasone valerate 1% Hidrokortison acetate
Cream 0,05% Desonide 0,25% Metilprednisolon acetate
Cream, 0,01% Fluosinolon acetonide Deksametason
Solution Prednisolon
Glumetalon
Penggolongan Penyakit
Gol I & II GOL III - V GOL VI - VII
• Psoriasis • Dermatiti atopik • Dermatitis pada kelopak
• Liken Planus • Dermatitis numular mata
• Dermatitis berat pada tangan • Dermatitis Asteatotik • Dermatitis pada area
• Liken simplex kronikus • Dermatitis statis popok
• Dermatitis hiperkeratotik • Dermatitis Seboroik • Dermatitis ringan pada
• Dermatitis numular • Liken schlerosis et atrofikus wajah
• Dermatitis Atopik (pasien (Vulva • IntertInflamasi anal
dewasa resistan) • Intertrigo berat ringan
• Dermatitis berat pada wajah • Intetrigo ringan
• Inflamasi anl berat
Aplikasi Klinis

Pemakaian
secara umum: 2-
Lama pemakaian tidak
3x Sehari
lebih dari
sampai sembuh
4 – 6 minggu (potensi
lemah) dan 2 minggu
(potensi kuat)
FTU = 0,5 gr dan luas
permukaan untuk 2 telapak
tangan
Efek Samping

Penggunaan Lama dan Penggunaan Berlebihan akan timbul efek


samping dengan gejala:

 Atrofi  Hipopigmentasi

 Strie atrofise  Dermatitis perioral

 Teleangiektasis  Megnhambat penyembuhan


ulkus
 Purpura
 Infeksi mudah terjadi dan
 Dermatosis akneformis meluas
 Hipertrikosis setempat

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