Scribd
Upload
59 views25 pages

Subcutaneous Mycosis: R.Varidianto Yudo T., Dr.,Mkes

This document summarizes several subcutaneous fungal infections: Sporothricosis is caused by the dimorphic fungus Sporothrix schenckii found on vegetation. It causes local skin nodules and ulcers along lymphatic drainage from skin introduction by a thorn. It is treated with oral antifungals and lesions may be chronic with little systemic illness. Chromoblastomycosis is caused by several soil fungi that form wartlike skin lesions and crusting abscesses along lymphatics from skin trauma. Microscopic examination shows dark brown fungal cells. It is treated with oral antifungals and surgery. Mycetoma features abscesses and pus discharge

Uploaded by

wawan siswoko
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
59 views25 pages

Subcutaneous Mycosis: R.Varidianto Yudo T., Dr.,Mkes

This document summarizes several subcutaneous fungal infections: Sporothricosis is caused by the dimorphic fungus Sporothrix schenckii found on vegetation. It causes local skin nodules and ulcers along lymphatic drainage from skin introduction by a thorn. It is treated with oral antifungals and lesions may be chronic with little systemic illness. Chromoblastomycosis is caused by several soil fungi that form wartlike skin lesions and crusting abscesses along lymphatics from skin trauma. Microscopic examination shows dark brown fungal cells. It is treated with oral antifungals and surgery. Mycetoma features abscesses and pus discharge

Uploaded by

wawan siswoko
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
You are on page 1/ 25

SUBCUTANEOUS

MYCOSIS

R.Varidianto Yudo T., dr.,MKes


Lab. Mikrobiologi
Fakultas Kedokteran Universitas
Hang Tuah Surabaya
SPOROTRICHOSIS
Sporothrix schenckii is a dimorphic
fungus that lives on vegetation.
When introduced into the skin,
typically by a thorn, it causes a
local pustule or ulcer with nodules
along the draining lymphatics.
There is little systemic illness.
Lesions may be chronic.
Small ulcer (sporotrichotic chancre) followed by the development of
erythematous nodules along the line of lymphatic drainage, leading to
the characteristic linear pattern. Regional adenopathy may follow as
well.
 In the clinical laboratory, round or cigar-
shaped budding yeasts are seen in
tissue specimens.
 In Culture, hyphae occur bearing oval
conidia in clusters at the tip of slender
conidiophores (resembling a daisy).
 The disease is treated with oral
potassium iodide or ketoconazole.
 It can be prevented by protecting skin
when touching plants, moss, and wood.
Depending on the conditions and the strain of fungus, sometimes
sections of the lesion contain cigar bodies or asteroid bodies instead of
(or in addition to) the yeasts.

Yeast Asteroid bodies Cigar bodies


Cultures at different temperature
Sporothrix schenckii at room temperature ( 25C )
Sporothrix schenckii at room temperature ( 25C )
Sporothrix schenckii at temperature 37C.
Spherical or oval budding yeast cells
CHROMOMYCOSIS
 This is a slowly progressive
granulomatuous infection that is caused by
several soil fungi (Fonsecaea,
Phialophora, Cladosporium, etc) when
introduced into the skin through trauma.
 These fungi are collectively called
dematiaceous fungi, so named because
they produce melanin-like pigments.
 Wartlike lesion with crusting abscesses
extend along the lymphatics.
Phialophora verrucosa
Cladosporium carrionii
Chromoblastomycosis, syn. chromomycosis; hyperkeratotic lesions
foot; Fonsacaea (Phialophora) infection
Chromoblastomycosis
The disease occurs mainly in the
tropics and is found on bare feet
and legs.
In the clinical laboratory, dark
brown, round fungal cells are seen
in leukocytes or giant cells.
The disease is treated with oral
flucytosine or thiabendazole, plus
local surgery.
Example of chromomycosis.
The organisms are pigmented and some are septated
Sclerotic cells, chromoblastomycosis.
MYCETOMA
Syn. Eumycotic Mycetoma
Soil organisms (Petriellidium,
Madurella mycetomatis) enter
through wounds on the feet, hands,
or back and cause abscesses, with
pus discharged through sinuses.
The pus contains compact colored
granules.
Early stages of mycetoma of the foot, caused by Madurella.
Ulceration, swelling and scarring are visible
Actinomycetes such as Nocardia
and Actinomyces can cause similar
lesions (actinomycotic mycetoma).
Sulfonamides may help the
actinomycotic form.
There is no effective drug against
the fungal form; surgical excision is
recommended.
ACTINOMYCOSIS (Lumpy Jaw)
Typical grain or granule of Actinomyces spp
Actinomycosis
Typical granule ( Splendore-Hoepplei )
TERIMA KASIH

You might also like