Infection and Bacterial Invasion
Infection and Bacterial Invasion
AND INFECTION
DEFINITION OF TERMS
Pathology
Scientific study of disease
Concerned with the etiology
and the manner in which a
disease develops
Deals with structural and
functional changes
DEFINITION OF TERMS
Infection
The invasion of
microorganisms
in the body
Disease
Changes in the
state of health
due to infection
G Y O F
I O L O
ET O U S
F EC T I
I N S E S
S E A
DI
CLASSIFYING
INFECTIOUS DISEASES
According to Occurrence
According to Severity or Duration
According to Extent of Host Involvement
DEFINITION OF TERMS
SYMPTOM
S
SIGNS
SYNDROM
E
DEFINITION OF TERMS
COMMUNICABLE DISEASE
CONTAGIOUS DISEASE
NON-COMMUNICABLE DISEASE
CLASSIFICATION ACCORDING TO
OCCURRENCE OF A DISEASE
INCIDENCE
Number of new
cases of a disease
in a defined
population
during a specific
time period
CLASSIFICATION ACCORDING TO
OCCURRENCE OF A DISEASE
PREVALENCE
Number of people
in a population
who developed
the disease at a
specified time, Period Prevalence
regardless of Point Prevalence
CLASSIFICATION ACCORDING TO
OCCURRENCE OF A DISEASE
PREVALENCE
Period Prevalence – no. of cases of the
disease existing in a pop. during a spec.
time period
Point Prevalence - no. of cases of the
disease existing in a pop. @ a particular
moment in time
CLASSIFICATION ACCORDING TO
FREQUENCY OF OCCURRENCE
SPORADIC ENDEMIC
EPIDEMIC PANDEMIC
CLASSIFICATION ACCORDING TO
SEVERITY OR DURATION OF DISEASE
FOCAL BACTEREMIA
INFECTION
SEPTICEMIA
TOXEMIA VIREMIA
CLASSIFICATION ACCORDING TO
EXTENT OF HOST INVOLVEMENT
According to
Host Resistance
PRIMARY INFECTION
Predisposing Factors
Development of Disease
CHAIN OF INFECTION
PREDISPOSING FACTORS
Is one that makes the
body more
susceptible to a
disease and may alter
Gender,
the Genetic, Climate
course of the
Inadequate nutrition Habits
disease
Emotional disturbances
Preexisting illness Lifestyle
Occupation Fatigue Age
Environment Chemotherapy
DEVELOPMENT OF DISEASE
1. INCUBATION PERIOD
2. PRODROMAL PERIOD
3. PERIOD OF ILLNESS
4. PERIOD OF DECLINE
5. PERIOD OF CONVALESCENCE
INCUBATION PERIOD
A relatively short
period that follows
the period of
incubation
Characterized by
early, mild
symptoms of disease,
such as general
PERIOD OF ILLNESS
The patient is
vulnerable to
PERIOD OF CONVALESCENCE
The person
regains strength
and the body
returns to its pre-
diseased state
Recovery occurs
THE SPREAD OF
INFECTION
Reservoirs of Infection
Transmission of Disease
RESERVOIR
For a disease
to perpetuate
itself, there
must be a
continual
source of the
disease
HUMAN RESERVOIR
CARRIER
Passive Carrier
Incubatory
Carrier
Convalescent
Carrier
Active Carrier
ANIMAL RESERVOIR
Includes both
wild & domestic
animals
ZOONOSES
ARTHROPOD RESERVOIR
Includes insects
& arachnids
VECTORS
NONLIVING RESERVOIR
2 Major
Nonliving
Reservoirs:
1. Soil
2. Water
TRANSMISSION OF DISEASE
3 Principal
Routes:
1. Contact
2. Vehicle
3. Vector
CONTACT TRANSMISSION
DIRECT INDIRECT
DROPLET
INDIRECT CONTACT
IT E S
F O M
FOMITES
VEHICLE TRANSMISSION
FOODBORNE
AIRBORNE
WATERBORNE
VECTOR TRANSMISSION
2 General Methods:
MECHANICAL
TRANSMISION
when pathogen is carried
passively, by feet or other
body parts of insects
BIOLOGICAL
TRANSMISSION
MODES OF DISEASE
TRANSMISSION