Skeletal System: Nor Fadila Kasim FSSKJ Upsi
Skeletal System: Nor Fadila Kasim FSSKJ Upsi
• Cartilage:
• Tendons:
attach bone to muscle
• Ligaments:
attach bone to bone
2
Skeletal System-function
1. Support and provide
attachment for skeletal
muscle
2. Protect internal organs
3. Assist in movement
4. Storage minerals
5. Contains red bone
marrow for produce
blood cell and yellow
bone marrow which
store triglycerides
3
Background Information
• Bones, cartilage, tendons, and ligaments are
connective tissues.
• Proteoglycans:
- large polysaccharides attached to proteins
- store water
4
• Bone’s extracellular matrix is collagen and
minerals (flexible and able to bear weight)
5
Classification of Bones
• Based on shape:
long, short, flat, irregular,sesamoid
6
7
Bone Shapes
• Sesamoid:
– patellae
• Long:
- Ex. Femur, tibia, fibula
• Short:
– Ex. Carpals, tarsals,
phlanges
• Flat:
– Ex. Ribs, sternum, skull
• Irregular:
– Ex. Vertebrae and facial
8
(1) LONG BONE
Long bones have greater length than width and consist of a shaft and a variable
number of ends. They are usually somewhat curved for strength. Long bones
include those in the thigh (femur), leg (tibia and fibula), arm (humerus), forearm
(ulna and radius), and fingers and toes (phalanges).
13
Long Bone Structures
• Diaphysis:
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tissue
Epiphysis
Epiphyseal plates
in juveniles
– Epiphysis:
– ends Spongy bone
• Articular cartilage:
Diaphysis red marrow in juveniles and
yellow marrow in adults)
- covers epiphyses
Periosteum
Endosteum
(a)
14
• Epiphyseal plate:
– site of growth
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Articular cartilage
Epiphysis
– between diaphysis
and epiphysis Epiphyseal lines
in adults
Spongy bone
Compact bone
Endosteum
– red or yellow
marrow (b)
Adult bone
• Periosteum:
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Articular cartilage
Epiphysis
Compact bone
Periosteum
Young bone
(a)
16
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Articular cartilage
Epiphysis
Epiphyseal plates
in juveniles
Epiphyseal lines
in adults
Spongy bone
Compact bone
Periosteum
Endosteum
Young bone
Adult bone
(a) (b)
Osteons
(haversian systems)
Endosteum
Inner
layer
Periosteum
Outer
layer
Compact bone
Central canals
Spongy bone
with trabeculae
Connecting vessels
Medullary
cavity
17
Adult bone
(c)
Divisions of the Skeletal System
• Lacunae:
spaces between lamella, with osteocytes
• Canaliculi:
- tiny canals
- transport nutrients and
remove waste
• Central canal:
- center of osteon
- contains blood vessels, nerve,
lymphatic
46
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Blood vessels
within a central
(Haversian) canal
Canaliculi
LM 400x Osteocytes in
lacunae
Canaliculi (b)
(a)
Blood vessel
Lacunae
connecting to
a central canal
between osteons
a: © Trent Stephens
Spongy Bone Tissue
• Cancellous bone
• Location: epiphyses of long bones and center of other bones
• Trabeculae: interconnecting rods, spaces contain marrow
• No osteons
48
BONE FORMATION
The process of bone formation is called OSSIFICATION (ossi=
bone, fication = making)
2 pattern of bone formation
Intramembranous ossification (within connective tissue membrane)
Endochondral ossification (bone forms within hyaline cartilage)
bone formation occurs in 4 principle situation:
1) initial formation of bones in an embryo and fetus
2) the growth of bone during infancy, childhood and adolescent until their
adult sizes are reached.
3) the remodelling of bone (replacement of old bone tissue by new bone tissue
throughout life)
4) the repair of fracture (break in bone)
Bone Cells
50
Bone Formation
• Ossification:
process of bone formation
• Osteoblast’s role:
- build bone
- after an osteoblast becomes surrounded by bone
matrix it becomes an osteocyte
51
Bone Formation
57
Steps in Endochondral Ossification
1. Chondroblasts build a cartilage model, the
chrondroblasts become chondrocytes.
2. Cartilage model calcifies (hardens).
3. Osteoblasts invade calcified cartilage and a
primary ossification center forms diaphysis.
4. Secondary ossification centers form epiphysis.
5. Original cartilage model is almost completely
ossified and remaining cartilage is articular
cartilage.
58
BONE FORMATION –
FRACTURES
A fracture (FRAK-choor) is any
break in a bone. Types of
fractures include the following:
Partial: an incomplete break across
the bone, such as a crack.
Complete: a complete break across
the bone; that is, the bone is broken
into two or more pieces.
Closed (simple): the fractured bone
does not break through the skin.
Open (compound): the broken
ends of the bone protrude through
the skin.
Bone Remodeling
• What is it?
- removal of existing bone by osteoclasts and
deposition of new bone by osteoblasts
- occurs in all bones
- responsible for changes in bone shape, bone
repair, adjustment of bone to stress, and
calcium ion regulation
61
Bone Repair
1. Broken bone causes bleeding and a blood clot
forms.
2. Callus forms which is a fibrous network between
2 fragments.
3. Cartilage model forms first then, osteoblasts
enter the callus and form cancellous bone this
continues for 4-6 weeks after injury.
4. Cancellous bone is slowly remodeled to form
compact and cancellous bone.
62
EXERCISE AND BONE TISSUE
In angular movements, there is a change in the angle between bones. Examples are
flexion–extension, hyperextension, abduction–adduction, and circumduction.
Special movements occur at specific synovial joints in the body. Examples are as
follows: elevation–depression, protraction–retraction, inversion–eversion,
dorsiflexion–plantar flexion, and supination–pronation.
Abduction- ab (away)
Adduction- ad- toward
Types of Movements at Synovial
Joints
91
Steps in Endochondral Ossification
1. Chondroblasts build a cartilage model, the
chrondroblasts become chondrocytes.
2. Cartilage model calcifies (hardens).
3. Osteoblasts invade calcified cartilage and a
primary ossification center forms diaphysis.
4. Secondary ossification centers form epiphysis.
5. Original cartilage model is almost completely
ossified and remaining cartilage is articular
cartilage.
92
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Femur
Patella
Epiphysis
Epiphyseal
plate
Diaphysis
(a)
Length of bone
increases.
Epiphyseal side
1 New cartilage is
Thickness of produced on
1 epiphyseal the epiphyseal side
plate remains of the plate as the
Chondrocytes 1
unchanged. chondrocytes divide
Epiphyseal divide and enlarge.
and form stacks
plate of cells.
2 2 Chondrocytes
mature and 2
Bone is
3 added to enlarge.
Calcified cartilage diaphysis. 3 Matrix is calcified,
is replaced by bone. and chondrocytes
die. 3
Bone of
4 The cartilage on
diaphysis
4 the diaphyseal side 4
of the plate is LM 400x
(b) replaced by bone.
Diaphyseal side
(c)
(a): © Ed Reschke/Peter Arnold, Inc./ Photolibrary.com; (c): © Bio-Photo Assocs/Photo Researchers, Inc.
94
Bone Growth
• Infancy and youth:
- long bones lengthen at epiphyseal plate
- long bones widen by adding more lamella
95
Figure
6.2b
Bone Remodeling
• What is it?
- removal of existing bone by osteoclasts and
deposition of new bone by osteoblasts
- occurs in all bones
- responsible for changes in bone shape, bone
repair, adjustment of bone to stress, and
calcium ion regulation
97
Bone Repair
1. Broken bone causes bleeding and a blood clot
forms.
2. Callus forms which is a fibrous network between
2 fragments.
3. Cartilage model forms first then, osteoblasts
enter the callus and form cancellous bone this
continues for 4-6 weeks after injury.
4. Cancellous bone is slowly remodeled to form
compact and cancellous bone.
98
Bone and Calcium Homeostasis
• Bone is a major storage site for calcium
• Movement of calcium in and out of bone helps
determine blood levels of calcium
• Calcium moves into bone as osteoblasts build
new bone
• Calcium move out of bone as osteoclasts break
down bone
• Calcium homeostasis is maintained by
parathyroid hormone (PTH) and calcitonin
100
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Decreased Increased
1 5
blood Ca2+ blood Ca2+
Posterior aspect
of thyroid gland
Parathyroid 1 Decreased blood Ca2+ stimulates PTH
glands secretion from parathyroid glands.
Kidney
Thyroid gland 2 PTH stimulates osteoclasts to break down
bone and release Ca 2+ into the blood.
Ca2+ Blood
Hematopoietic Tissue
• What is it?
tissue that makes blood cells
• Red marrow:
location of blood forming cells
• Yellow marrow:
mostly fat
102
• Location of hematopoietic tissue in newborns:
most bones (red marrow)
103
Bone Anatomy
• Foramen:
- hole
- Ex. Foramen magnum
• Fossa:
- depression
- Ex. Glenoid fossa
• Process:
- projection
- Ex. Mastoid process 104
• Condyle:
- smooth, rounded end
- Ex. Occipital condyle
• Meatus:
- canal-like passageway
- Ex. External auditory meatus
• Tubercle:
- lump of bone
- Ex. Greater tubercle
105
106
Axial Skeleton
• Mastoid process:
attached to neck muscles
• Nasolacrimal canal:
- canal between nasal cavity and eye
- conducts tears
107
• Styloid process:
attachment site for tongue
• Mandibular fossa:
depression where lower jaw and skull
meet
• Glenoid fossa:
where humerus meets scapula
108
• Hard palate:
roof of mouth
• Foramen magnum:
hole where spinal cord joins brainstem
109
• Zygomatic:
cheek bone
• Mandible:
lower jaw
• Maxilla:
upper jaw
110
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Incisive fossa
Maxilla
Foramen ovale
Foramen spinosum Styloid process
Mandibular fossa
External auditory canal Carotid canal
Jugular foramen
Occipital condyle Mastoid process
Occipital bone
Nuchal lines
• Movement
119
Thoracic Cage
• Protects vital organs
• 12 pair of ribs
• Sternum:
breastbone
• True ribs:
attach directly to sternum by cartilage
• False ribs:
attach indirectly to sternum by cartilage
• Floating ribs:
not attached to sternum 120
Pectoral Girdle
• Scapula:
shoulder blade
• Clavicle:
collar bone
122
Upper Limb Bones
• Humerus:
upper limb
• Ulna:
forearm
• Radius:
forearm
• Carpals:
wrist
• Metacarpals:
hand 124
Pelvic Girdle
• Where lower limbs attach to body
• Pelvis:
includes pelvic girdle and coccyx
• Ischium:
inferior and posterior region
• Ilium:
most superior region
• Acetabulum:
hip socket (joint) 129
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Iliac crest
Ilium Articular surface
(area of
Iliac fossa articulation
with sacrum)
Ischium
Pubic symphysis
Obturator foramen
Ischial tuberosity
(a) Lateral view (b) Medial view
133
Lower Limb Bones
• Femur:
thigh
• Patella:
knee cap
• Tibia:
large lower leg
• Fibula:
small lower leg
134
• Tarsals:
ankle
• Metatarsals:
foot
• Phalanges:
toes and fingers
135
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Head Head
Neck Neck
Lesser trochanter
Linea aspera
Medial
epicondyle
Lateral epicondyle
(b) Anterior
surface
137
Anterior view
140
Articulations
• What are they?
where 2 bones come together (joint)
• Synarthrosis:
- nonmovable joint
- Ex. skull
• Amphiarthrosis:
- slightly movable joint
- Ex. Between vertebrae
• Diarthrosis:
- freely movable joint
- Ex. knee, elbow, wrist 141
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Parietal
bone
Frontal
Squamous bone
suture
Coronal
suture
Occipital
bone
Lambdoid
suture
Mastoid (posterolateral)
fontanel
Sphenoidal
(anterolateral)
fontanel
Temporal bone
(a) Lateral view
Frontal bones
(not yet fused
into a single
bone)
Frontal
(anterior)
fontanel
Parietal
Sagittal
bone
suture
Occipital
(posterior)
fontanel
Occipital 142
bone
(b) Superior view
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Bone
Synovial membrane
Joint
Blood vessel Fibrous part of joint capsule
Nerve capsule
Bursa
Tendon
sheath
143
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Saddle
Carpometacarpal Carpal and metacarpal Two axes
pollicis of thumb
Intercarpal Between carpal bones Slight
Sternoclavicular Manubrium of sternum Slight
and clavicle
Saddle
Hinge
Cubital (elbow) Humerus, ulna, and radius One axis
Knee Femur and tibia One axis
Interphalangeal Between phalanges One axis
Talocrural (ankle) Talus, tibia, and fibula Multiple axes;
one predominates
Hinge
Pivot
Medial atlantoaxial Atlas and axis Rotation
Proximal radioulnar Radius and ulna Rotation
Distal radioulnar Radius and ulna Rotation
Pivot
Ball-and-Socket
Coxal (hip) Coxal bone and femur Multiple axes
Humeral (shoulder) Scapula and humerus Multiple axes
Ball-and-socket
Ellipsoid
Atlantooccipital Atlas and occipital bone Two axes
Metacarpopha- Metacarpal bones and Two axes
langeal (knuckles) phalanges
Metatarsopha- Metatarsal bones and Two axes
langeal (ball of foot)
Radiocarpal (wrist)
phalanges
Radius and carpal bones Multiple axes 144
Temporomandibular Mandible and temporal bone Multiple axes;
Ellipsoid one predominates
Types of Movement
• Flexion: bending
• Extension: straightening
• Abduction: movement away from midline
• Adduction: movement toward the midline
• Pronation: rotation of the forearm with palms
down
• Supination: rotation of the forearm with palms up
• Rotation: movement of a structure about the long
axis
145
Effects of Aging on the Skeletal
System and Joints
1. Decrease Collagen Production
2. Loss of Bone Density
3. Degenerative Changes
148