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(1) Guillain-Barre syndrome is a rare autoimmune disorder where the immune system damages the nerves, causing muscle weakness and sometimes paralysis. (2) While the exact cause is unknown, two-thirds of patients report an infection in the six weeks prior. (3) Treatment involves plasmapheresis to remove plasma from the blood in the first two weeks, intravenous immune globulin, and supportive care such as respiratory therapy and nutrition if muscles are affected.

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560 views2 pages

Concept Map

(1) Guillain-Barre syndrome is a rare autoimmune disorder where the immune system damages the nerves, causing muscle weakness and sometimes paralysis. (2) While the exact cause is unknown, two-thirds of patients report an infection in the six weeks prior. (3) Treatment involves plasmapheresis to remove plasma from the blood in the first two weeks, intravenous immune globulin, and supportive care such as respiratory therapy and nutrition if muscles are affected.

Uploaded by

Skyla Fiesta
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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The exact cause of Guillain-Barre syndrome is

GUILLAIN-BARRÉ Due to unknown. But two-thirds of patients report symptoms


SYNDROME of an infection in the six weeks preceding. These
means include respiratory or a gastrointestinal infection or
Zika virus.
treatment

Plasmapheresis, removal of plasma from


rare, autoimmune disorder in which a
the blood, and rein-fusion of the cellular
person's own immune system damages
components with saline have been shown May cause
the nerves, causing muscle weakness
to shorten the course of the disease if
and sometimes paralysis. GBS can cause
performed within the first 2 weeks. The
symptoms that last for a few weeks to paralysis of the muscles that
administering of intravenous immune
several years. Most people recover fully, control breathing, blood
globulin known as Gamimune N soon after
but some have permanent nerve infection, lung clots, or cardiac
symptoms manifest may enhance
damage. arrest.
improvement. Otherwise, treatment is
primarily supportive.  If the respiratory
muscles are involved, endotracheal treatment
Signs and symptoms intubation and mechanical ventilation
become necessary. Difficulty chewing and
Diagnostic Tests swallowing necessitate the administration of
IV fluids, gastric tube feedings, or total • respiratory therapy
parenteral nutrition (TPN). • cardiac monitoring
Although symptoms vary, weakness, numbness, and • safe nutritional
tingling in the arms and legs that the client may supplementation
perceive as painful often are the first symptoms. • Monitoring for infectious
The weakness is progressive and moves to the complications (eg,
A lumbar puncture reveals elevated CSF protein levels pneumonia, urinary tract
upper areas of the body and affects the muscles of
and pressure. The results of electrophysiologic testing infections, septicemia)
respiration. Paralysis may follow muscle weakness.
show marked slowing in the conduction of nerve
If cranial nerve involvement develops, chewing,
impulses. Additional neurologic tests are performed to
talking, and swallowing become difficult.
rule out other possible CNS disorders with similar
symptoms.

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