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Prescription Writing: Esha Ann Franson

Esha Ann Franson

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Alosious John
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111 views9 pages

Prescription Writing: Esha Ann Franson

Esha Ann Franson

Uploaded by

Alosious John
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Prescription

Writing
ESHA ANN FRANSON
Exercise B8- Absence
Seizures
A 9 year old was bought with history of not doing well in class. on questioning the parents,
say they noticed she frequently stares into space and seems to be out of touch with her
surroundings for brief spells. The EEG was done and showed 3 cycles per second spike and
wave activity. A diagnosis of absence seizures was made. Write a suitable prescription for
this patient.
Absence seizures
Absence seizures, also known as Petit Mal seizures, are a type of Other Symptoms
epileptic disorders, characterized by a transient loss of
Brief unconscious behaviors
conciousness, without prominent convulsive episodes. Symptoms
(automatisms)
are generally breif, have a sudden onset that interrupts ongoing
Minimal bilateral jerking or blinking
activites.
of eyes
Brief involuntary muscle twitching
Outside factors that may trigger seizure activity include emotions, (myoclonia).
time of day, metabolic factors (including hyperventilation), and
periods of changing attentiveness.
Absences are triggered in the thalamus when T-
type calcium channels are activated, resulting in
sustained burst firing of these neurons. The
neurotransmitter GABA is involved in the
polarisation of these channels, which potentiates
the sustained-burst firing.
Pathophysiology

EEG shows characteristic 3 cycles per second


spike and wave pattern
Treatment
Antiepileptics are the drugs given for absence seizures. They do not cure the disorder but helps to
control and prevent all seizure activity at an acceptable level of side effects. Treatment is to be
initiated early because each seizure episode increases prospensity to further attacks.

Aliphatic Carboxylic Succinimides Phenyltriazene Benzodiazepines Newer Drugs


Acids Clobazam Leviteracetam
Ethosuximide Lamotrigmine
Valproic Acid Clonazepam Topiramide
Zonisamide
Choosing appropriate drug group
Why Not Ethosuximide?

Has dose related side effects such as gastro-intestinal tolerance, tiredeness, mood changes, agitation,
headache, inability to concentrate. Hypersensitivity reactions like rashes, DLE and blood dyscarias
could also occurl.
Why Not Lamotrigmine?

Valproate levels are lowered by lamotrigmine. The half life of lamotrigmine is reduced to 16 hours
in patients receiving phenytoin, carbamazepine or phenobarbitone.
Why Not Benzodiazepines?

Clonazepam has adverse effects of sedation and dullness, some tolerance develops with chronic
therapy. Lack of concentration, irritability and behavioural disorders are seen in children.
It is the drug of choice for absence seizures.
Due to it's tolerability, it can also be given for myoclonic and

DRUG OF partial seizures.


It is widely used in pediatric epilepsy because of its multiple

CHOICE - mechanisms of action and acceptable safety profile.


Valproic acid is rapidly absorbed from the gastrointestinal tract,

Sodium valproate peak concentrations being attained 1 to 2 hours.


The bioavailability of valproic acid is complete and
independent of the preparation used.
Valproic acid is quickly absorbed when taken by mouth.
Step 1 Define the patient's Absence seizures
problem
Antiepileptic drugs to
Specify the therapeutic
Step 2 control and prevent
objective
Selection of P- Step 3 Inventory of effective drug
seizure activity
Succinamides, valproic

Drug groups acids, phenyltriazene


benzodiazipenes
Choose appropriate drug
Step 4 Aliphatic carboxylic acid-
group and verify suitability
Valproic acid
of your P drug treatment
SODIM VALPROATE
Step 5 Write Prescription
200 mg/5ml syrup

Give information- Give one tsp full of syrup


Step 6 instructions and warnings of 5ml twice a day
Prescription
MOSC MEDICAL COLLEGE HOSPITAL- KOLENCHERY
Dr. Esha Ann Franson Reg no:5637 Tel No:74398256 Dated 29/11/2021

Miss Anjana, 9 y/o, Female, Ernakulam, Hosp No;82367


Diagnosis: Absence seizures
Rx
- SODIUM VALPROATE 200mg/5 ml syrup x 1 bottle of 60ml
Give the child ONE teaspoon full syrup 5ml twice a day
Review after 5 Days
Signature

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