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Local Anesthetics Overview

Local anesthetics work by blocking nerve endings and are classified as amides, esters, or miscellaneous agents. Lignocaine is a commonly used amide local anesthetic that is odorless, bitter tasting, and soluble in both organic solvents and water. It is used for local anesthesia, treatment of cardiac arrhythmias, dental anesthesia, nerve blocks, and minor surgeries. Procaine and benzocaine are other examples of local anesthetics that are also odorless, bitter tasting, and soluble in water. They are used for local anesthesia and pain relief.

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70 views11 pages

Local Anesthetics Overview

Local anesthetics work by blocking nerve endings and are classified as amides, esters, or miscellaneous agents. Lignocaine is a commonly used amide local anesthetic that is odorless, bitter tasting, and soluble in both organic solvents and water. It is used for local anesthesia, treatment of cardiac arrhythmias, dental anesthesia, nerve blocks, and minor surgeries. Procaine and benzocaine are other examples of local anesthetics that are also odorless, bitter tasting, and soluble in water. They are used for local anesthesia and pain relief.

Uploaded by

rushikesh ugale
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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Local Anesthetics

Ms. Sneha J. Sawant


• Definition:
these are the drugs which produce loss of pain
sensation in limited area without loss of
consciousness.

MOA: by blocking nerve endings.


Classification
Local
Anesthetics

Amides Miscellaneo
us agents

Ester of p- Anilide Non - Anilide Eugenol


amino derivative derivative Phenol
enzoic acid ( Lignocain ( Cinchocaine Benzyl
( Procaine, e) ) alcohol
enzocaine)
***Lignocaine

Physical properties:
• WCP, Odorless, bitter in taste .
• Soluble in organic solvent and water.

Storage: WCC
Uses: it is used as
- Local anesthetic
- Treatment of cardiac arrythmia
- Dental anesthesia.
- Nerve block
- As minor anesthetic for various minor surgeries.
Official preparation:
- Lignocaine I.P./B.P.
- Lignocaine injection I.P./B.P.
- Lignocaine gel I.P./B.P.
- Lignocaine ointment I.P./B.P.
- Lignocaine ear drop I.P./B.P.
- Lignocaine eye drop I.P./B.P.
- Lignocaine solution I.P./B.P.
Brand Name:
1. LOX 2%
2. Scolin
3. Lidfast 2% jelly
4. LOX heavy 5 % ( for spinal anesthesia)
5. Otek
6. Xylocaine
Procaine
Physical properties:
• WCP, Odorless, bitter in taste .
• Freely Soluble in water.
Storage: WCC
Uses: used to produce:
- Local anaesthesia
- Dental anaethesia
- peripheral nerve block.
- Procaine + benzl penicilline --- duration of action
Official preparation:
- Procaine I.P. / B.P.
- Procaine Adrenaline injection I.P. / B.P.
- Procaine Hydrochloride injection I.P. / B.P.
- Procaine benzyl penicilline injection I.P. / B.P.

Brand names:
- Pronestyl
- Planocaine
- Xylocaine
- Novacaine
Benzocaine

Physical properties:
• WCP, Odorless, bitter in taste .
• Freely Soluble in water.

• Storage : WCC
Uses:
- Used as local anesthetic
- To relieve pain related to ulcers and wounds.
- To treat nausea and vomiting due to systemic toxicity.
- To treat T.B.
- To treat Laryngitis.
Official preparation:
- Benzocaine I.P. / B.P.
- Benzocaine ointment I.P. / B.P.
- Benzocaine spray I.P. / B.P.
- Benzocaine lotion I.P. / B.P.
- Benzocaine lozenges I.P. / B.P.
- Benzocaine cream I.P. / B.P.
- Benzocaine Aerosol I.P. / B.P.
Brand names:
Benzoscap
Omedia
Oticaine

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