IB Biology 2016 - 1.1 - Intro To Cells
IB Biology 2016 - 1.1 - Intro To Cells
1 – INTRO TO CELLS
1.1 – A – Cell Theory
IB BIO – 1.1 Biology is the study of living organisms and matter in all forms. Its
3
INTRO
https://aos.iacpublishinglabs.com/question/aq/1400px-788px/complex-organism_a16ec757bc0b68d7.jpg
IB BIO – 1.1 During the 17th century, cells were observed for the first time as a
4
http://news.nationalgeographic.com/content/dam/news/2016/01/11/01humancells.adapt.768.1.jpg
IB BIO – 1.1 The cell theory was developed as a result of several scientists’
5
• Theodor
Key Terms Schwann
http://1.bp.blogspot.com/-4VRMdnMWfhk/VPndRL-00-I/AAAAAAAAAiU/Lh__8A_vi6E/s1600/Untitled-3.png
IB BIO – 1.1 Robert Hooke was a scientist who used
6
Key Terms
http://41.media.tumblr.com/tumblr_m8fcq4AiAM1rdrl41o1_1280.png
IB BIO – 1.1 Hooke coined the term
7
Key Terms
Anton von
Leeuwenhoek
http://media.gettyimages.com/photos/animalcules-observed-by-anton-van-leeuwenhoek-c1795-handcoloured-picture-id463923335
IB BIO – 1.1 9
Understandings
U1: According
to the cell
theory, living
organisms are
composed of
cells.
Key Terms
http://bugs.adrianthysse.com/wp-content/uploads/2011/01/leeu-flea-2.jpg
IB BIO – 1.1 In 1838, Schleiden and Schwann proposed the cell theory.
10
Key Terms
Matthias
Schleiden
Theodor
Schwann
http://img2-ak.lst.fm/i/u/770x0/b37bae73cb504cf9a55f0e70ab523403.jpg
IB BIO – 1.1 Robert Virchow was a German
11
Key Terms
Robert
Virchow
https://upload.wikimedia.org/wikipedia/commons/e/e9/Rudolf_Virchow_NLM9.jpg
IB BIO – 1.1 During the 17th century, cells were observed for the first time as a
12
http://news.nationalgeographic.com/content/dam/news/2016/01/11/01humancells.adapt.768.1.jpg
IB BIO – 1.1 When testing cell theory, there
13
https://upload.wikimedia.org/wikipedia/commons/3/38/Skeletal_striated_muscle.jpg
IB BIO – 1.1 Fungi consist of long structures called hyphae. In aseptate fungi,
14
Applications the hyphae are long tube-like structures with many nuclei.
A1: Questioning
the cell theory
using atypical
examples,
including striated
muscle, giant
algae and
aseptate fungal
hyphae.
Key Terms
Aseptate
Fungal Hyphae
http://www.microbeorganics.com/Fungal%20Hyphae%20barn%20compost%20w%20mol.JPG
IB BIO – 1.1 Algae are photosynthetic organisms that are
15
Giant Algae
https://s3.amazonaws.com/note-pics/ib_guides_notes_545e54899960b.jpg
1.1 – B – Functions of Life
IB BIO – 1.1 All organisms, including unicellular, have similar abilities that 17
classify them as living entities. These are the functions of life.
Understandings
U2: Organisms
consisting of only
one cell carry out
all functions of
life in that cell.
https://aos.iacpublishinglabs.com/question/aq/1400px-788px/characteristics-multicellular-organisms_98abe8c570ad961f.jpg
https://aos.iacpublishinglabs.com/question/aq/1400px-788px/characteristics-multicellular-organisms_98abe8c570ad961f.jpg
IB BIO – 1.1 18
Functions of Life
Understandings
1. Metabolism
U2: Organisms
consisting of only Chemical reactions inside the cell
one cell carry out
all functions of including photosynthesis and cell
life in that cell. respiration
Guidance
Understandings
3. Growth
U2: Organisms
consisting of only Gradual increase in size over
one cell carry out
all functions of lifetime
life in that cell.
Guidance
Understandings
5. Excretion
U2: Organisms
consisting of only Getting rid of waste products of
one cell carry out
all functions of metabolism
life in that cell.
Guidance
Understandings
5. Reproduction - Producing offspring and passing on genes
U2: Organisms
consisting of only
one cell carry out
all functions of
life in that cell.
Guidance
Applications environments.
Applications environments.
Key Terms
Chlorella
http://i.huffpost.com/gen/2763600/images/o-CHLORELLA-facebook.jpg
IB BIO – 1.1 Paramecia are unicellular organisms that
24
http://i.huffpost.com/gen/2763600/images/o-CHLORELLA-facebook.jpg
IB BIO – 1.1 Paramecia are unicellular organisms that
25
http://i.huffpost.com/gen/2763600/images/o-CHLORELLA-facebook.jpg
IB BIO – 1.1 26
Understandings
U1:
Key Terms
Paramecium
https://www.youtube.com/watch?v=a4aZE5FQ284
1.1 – C – Emergence & Differentiation
IB BIO – 1.1 Individual cells are able to carry out the functions of life, but they
28
INTRO
https://adapaproject.org/images/biobook_images/plant_multicell.jpg
IB BIO – 1.1 Individual cells can fuse together to form multicellular organisms,
29
Understandings which are single masses of cells. Cells can organize into tissues,
organs, organ systems and ultimately form complex organisms.
U4: Multicellular
organisms have
properties that
emerge from
the interaction
of their cellular
components.
Key Terms
Multicellular
https://s3.amazonaws.com/user-media.venngage.com/361832-303bb4c522190ad5ee18243d935472fe.jpeg
IB BIO – 1.1 When cells fuse and organize, they develop emergent properties.
30
Understandings These are functions and properties that individual cells are not
capable of.
U4: Multicellular
organisms have
For example, individual
properties that
emerge from neurons are only capable of
the interaction receiving and sending
of their cellular
signals.
components.
http://jwilson.coe.uga.edu/BrainOnMusic/Fall2010-1.jpg
IB BIO – 1.1 In Biology, scientists usually describe emergent properties by saying
31
Understandings that the ‘whole is greater than the sum of its parts.’
U4: Multicellular
organisms have
properties that
emerge from
the interaction
of their cellular
components.
Key Terms
Emergent
Properties
http://www.thwink.org/sustain/glossary/images/EmergentBehavior_Diagram.png
IB BIO – 1.1 Specialized tissues in organism can develop by cell differentiation,
32
Understandings which is the process of cells developing the ideal structures needed
to carry out a particular function.
U5: Specialized
tissues can
develop by cell
differentiation in
multicellular
organisms.
Key Terms
Cell
Differentiation
http://ccftp.scu.edu.cn:8090/Download/uploadfile/20120812225140572.jpg
IB BIO – 1.1 There are 220 distinct types of specialized cells in the human body.
33
Understandings They form from various types of stem cells spread throughout body
tissues.
U5: Specialized
tissues can
develop by cell
differentiation in
multicellular
organisms.
Key Terms
Cell
Differentiation
http://image.tutorvista.com/content/feed/u2077/Multicellular%20Organisms.jpg
IB BIO – 1.1 Cell differentiation occurs as a
34
Key Terms
http://blogs.scientificamerican.com/a-blog-around-the-clock/files/2011/09/a2-cell-differentiation.gif
IB BIO – 1.1 Once differentiated, cells can further fuse and mature to form
35
Understandings specialized tissues. In the example here, cells specialize and fuse
to create muscle fibers.
U6: Differentiation
involves the
expression of
some genes and
not others in a
cell’s genome.
Key Terms
http://www.mun.ca/biology/desmid/brian/BIOL3530/DEVO_10/ch10f19.jpg
1.1 – D – Stem Cells
IB BIO – 1.1 Stem cells are specialized cells that have the ability to divide and
37
Key Terms
Stem Cell
http://www.nationalmssociety.org/NationalMSSociety/media/MSNational/Research/stemcell201607.jpg?ext=.jpg
IB BIO – 1.1 Stem cells have different levels
38
Understandings of potency.
Key Terms
Stem Cell
https://cdn.arizonapain.com/stemcell/wp-content/uploads/2014/07/hierarchy-of-stem-cells.jpg
IB BIO – 1.1 Stem cells have great potential for use in medical therapies. For 39
Key Terms
Stem Cell
http://http://www.leukaemiamyelomaresearchuk.org/wp-content/uploads/2015/10/humanstemcells.jpg=.jpg
IB BIO – 1.1 40
Understandings
U7: The
capacity of stem
cells to divide
and differentiate
along different
pathways is
necessary in
embryonic
development
and also makes
stem cells
suitable for
therapeutic
uses.
Key Terms
Stem Cell
https://upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Stem_cell_treatments.svg/2000px-Stem_cell_treatments.svg.png
IB BIO – 1.1 Embryonic stem cells are made by fertilizing eggs with sperm and
41
Applications allowing the zygote to develop. They have almost unlimited potential
and can differentiate into any cell type in the body.
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
Embryonic Stem
Cells
http://s3.amazonaws.com/libapps/accounts/1768/images/Embryonic_stem_cells_diagram.jpg
IB BIO – 1.1 42
Embryonic Stem Cells
Applications
BENEFITS DOWNFALLS
A4: Ethics of
Almost unlimited More risk of cells becoming
the therapeutic
use of stem differentiation potential a tumour
cells from Less chance of genetic Removing cells from the
specially damage via mutations embryo kills it
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
Embryonic Stem
Cells
http://d2qiws50qrj9uc.cloudfront.net/content/develop/140/4/705/F1.large.jpg
IB BIO – 1.1 Cord blood stem cells are extracted from the umbilical cord of
43
Applications new-born babies. These cells are pluripotent and can be frozen for
storage until needed later in life.
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
Umbilical Cord
Blood
http://www.cordbloodaware.org/wp-content/uploads/2016/01/Baby-Cord-shutterstock.jpg
IB BIO – 1.1 44
Umbilical Cord Blood Cells
Applications
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
Umbilical Cord
Blood
https://immyounology.files.wordpress.com/2014/09/hematopoiesis_simple.png
IB BIO – 1.1 45
Applications
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
Umbilical Cord
Blood
http://www.todayonline.com/sites/default/files/styles/photo_gallery_image_lightbox/public/photos/43_images/26315152.JPG
IB BIO – 1.1 46
Umbilical Cord Blood Cells
Applications
BENEFITS DOWNFALLS
A4: Ethics of
Easy to obtain and store Storage can be expensive
the therapeutic
use of stem Cells came from patient and Limited capacity to
cells from so are genetically compatible differentiate compared to
specially
created
embryonic stem cells
embryos, from Limited quantity in umbilical
the umbilical cord
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
Umbilical Cord
Blood
http://cmkml1r1zkj34mfam5798011.wpengine.netdna-cdn.com/wp-content/uploads/2016/01/umbilical-cord-stem-cell-banking-sgmt14.jpg
IB BIO – 1.1 Adult stem cells are those taken from an adult’s own tissues. They
47
Applications are harder to obtain and have less growth potential than other types.
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
https://drakebiomedicalinstitute.files.wordpress.com/2015/02/bedelldrawing.jpg
IB BIO – 1.1 48
Applications
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
http://learn.genetics.utah.edu/content/stemcells/quickref/somaticstemcells.jpg
IB BIO – 1.1 49
Applications
A4: Ethics of
the therapeutic
use of stem
cells from
specially
created
embryos, from
the umbilical
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
http://learn.genetics.utah.edu/content/stemcells/quickref/ips-cells.jpg
IB BIO – 1.1 50
Adult Stem Cells
Applications
BENEFITS DOWNFALLS
A4: Ethics of Less change of tumour Difficult to obtain from
the therapeutic
development deep in tissues
use of stem
cells from Full compatible with Less growth potential
specially patient’s tissues
created
embryos, from Removal of cells does not
the umbilical kill the adult
cord blood of a
new-born baby
and from an
adult’s own
tissues.
Key Terms
https://upload.wikimedia.org/wikipedia/commons/thumb/0/09/Induction_of_iPS_cells.svg/2000px-Induction_of_iPS_cells.svg.png
IB BIO – 1.1 Stargard’s disease an inherited conditoin that results in the
51
Applications degeration of the macula in the retina. It affects juveniles and can
result in blindness if untreated.
A3: Use of stem
cells to treat
Stargardt’s
disease and one
other named
condition.
Key Terms
Stargardt’s
Disease
http://www.alkeuspharma.com/images/fundus.jpg
IB BIO – 1.1 52
Applications
Key Terms
Stargardt’s
Disease
http://www.alkeuspharma.com/images/fundus.jpg
IB BIO – 1.1 In 2010, the US FDA approved stem cell research for treatment of
53
By 2020, approximately
200 million people will
Key Terms
be affected worldwide.
Stargardt’s
Disease
http://http://i.dailymail.co.uk/i/pix/2011/09/23/article-2040789-0E0AD53B00000578-500_468x407.jpg
IB BIO – 1.1 Acute leukemia is a form of cancer that stems from white blood cells
54
Applications inside the bone marrow. Cancerous cells invade the body quickly
from the blood stream. It can lethal if untreated.
A3: Use of stem
cells to treat
Stargardt’s
disease and one
other named
condition.
Key Terms
Leukemia
http://www.beveite.com/wp-content/uploads/2015/05/Leukemia.jpg
IB BIO – 1.1 Acute leukemia is a form of cancer that stems from white blood cells
55
Applications inside the bone marrow. Cancerous cells invade the body quickly
from the blood stream. It can lethal if untreated.
A3: Use of stem
cells to treat
Stargardt’s
disease and one
other named
condition.
Key Terms
Leukemia
https://upload.wikimedia.org/wikipedia/commons/3/3a/Symptoms_of_leukemia.png
IB BIO – 1.1 Chemotherapy can be used to kill the cancerous cells in the bone
56
Applications marrow, however this also affects the bodies ability to produce white
blood cells. Stem cell treatment can be used to address this.
A3: Use of stem
cells to treat • Before treatment, stem
Stargardt’s cells are removed from the
disease and one
other named marrow and frozen.
condition.
• After treatment, cells are
injected back into the body
to restore the ability to
produce white blood cells.
Key Terms
Leukemia
http://www.eurostemcell.org/files/Pediatric_patients_receiving_chemotherapy.jpg
IB BIO – 1.1 Leukemia Stem Cell Treatment
57
Applications
Key Terms
Leukemia
http://www.biologyjunction.com/images/maturestemcelltreatment.jpg
IB BIO – 1.1 58
1. Define stem cell.
specialization. However, there are limits how large they can grow.
INTRO
asdf
IB BIO – 1.1 A cell’s volume
61
Key Terms
http://images.wisegeek.com/animal-cell-drawing.jpg
IB BIO – 1.1 As a cell grows, its surface area (SA) and volume (V) do not
63
Understandings increase at the same rate. A high SA:V ratio is essential for a cells’
survival. To consider this, you can visualize cells as perfect cubes.
U3: Surface
area to volume
ratio is
important in the
limitation of cell
1µm
size.
2µm
3µm
Key Terms
4µm
5µm
6µm
IB BIO – 1.1 64
Fill in the chart below showing the surface area and volume of a cube
Understandings with the shown side size. The relevant equations are below.
U3: Surface
area to volume Size /
µm
1 2 3 4 5 6 7
ratio is
important in the
limitation of cell Surface
size. Area / µm2
Volume /
µm3
Key Terms
U3: Surface
area to volume Size /
µm
1 2 3 4 5 6 7
ratio is
important in the
limitation of cell Surface
size. Area / µm2
6 24 54 96 150 216 294
Volume /
µm3
1 8 27 64 125 216 343
Key Terms
U3: Surface
area to volume Size /
µm
1 2 3 4 5 6 7
ratio is
important in the
limitation of cell Surface
size. Area / µm2
6 24 54 96 150 216 294
Volume /
µm3
1 8 27 64 125 216 343
Key Terms
SA / V
IB BIO – 1.1 Now, calculate the surface area to volume ratio, by dividing the
67
U3: Surface
area to volume Size /
µm
1 2 3 4 5 6 7
ratio is
important in the
limitation of cell Surface
size. Area / µm2
6 24 54 96 150 216 294
Volume /
µm3
1 8 27 64 125 216 343
Key Terms
1 2 3 4 5 6 7 8 9 10
Side length (um)
IB BIO – 1.1 As seen in the graph, the SA:V ratio decreases exponentially as
69
Understandings cube side length increases. So, in order to grow cells must fix this.
SA:V Ratio vs Side length
U3: Surface
10
area to volume
ratio is 9
important in the
limitation of cell 8
size. 7
6
Surface
5
Area :
Volume 4
Key Terms
3
2
1
1 2 3 4 5 6 7 8 9 10
Side length (um)
IB BIO – 1.1 To maintain a high SA:V as they grow, cells have developed a
70
Key Terms
https://cdn-images-1.medium.com/max/800/0*C-RMOyH9FdGz83C4
IB BIO – 1.1 Other cells can change their
71
Understandings morphology:
http://library.med.utah.edu/WebPath/jpeg4/GI162.jpg
http://library.med.utah.edu/WebPath/jpeg4/GI162.jpg
IB BIO – 1.1 Lung cells and the roots of plants branch out. This gives lung cells
72
Understandings access to more air and plant cells more access to water.
U3: Surface
area to volume
ratio is
important in the
limitation of cell
size.
Key Terms
http://library.med.utah.edu/WebPath/jpeg4/GI162.jpg
http://library.med.utah.edu/WebPath/jpeg4/GI162.jpg
IB BIO – 1.1 73
1. What role does volume play in cell activity?
http://baileyb.pbworks.com/f/1391453862/Cell%20Surface%20to%20volume.gif
1.1 – F – Magnification
IB BIO – 1.1 75
http://http://www.microscope.com/media/catalog/product/cache/2/image/9df78eab33525d08d6e5fb8d27136e95/o/m/
IB BIO – 1.1 Calculating Magnification
76
Skills
When looking at images, magnification is often stated indicating the
S1: Calculation scale of the image
of the
magnification of
drawings and
the actual size A magnification could
of structures be directly stated
and
ultrastructures. • x 250
Guidance
G3 Scale bars
are useful as a Or indicated by means
way of of a scale bar
indicating actual
sizes in • |--------| = 1 μm
drawings and
micrographs.
https://s-media-cache-ak0.pinimg.com/236x/e8/01/fe/e801fefab74af11d4b36deb1c8a47ea4.jpg
IB BIO – 1.1 When viewing an image in a microscope or micrograph,
77
S1: Calculation
of the
magnification of Magnification = magnified size
drawings and
the actual size actual size
of structures
and
ultrastructures.
Guidance • Magnified size = the length of the scale bar provided in the image,
which can be measured with a ruler
G3 Scale bars
are useful as a
way of
indicating actual • Actual size = actual size represented by the scale bar
sizes in
drawings and
micrographs.
asdf
IB BIO – 1.1 Practice: What is the magnification of this image? (Note that the
78
Skills value with change depending the size of your screen or printout)
S1: Calculation
of the
magnification of
drawings and
the actual size
of structures
and
ultrastructures.
Guidance
G3 Scale bars
are useful as a
way of
indicating actual
sizes in
drawings and
micrographs.
https://s-media-cache-ak0.pinimg.com/736x/55/71/5b/55715bea56c65f34ad172bcd49dbdcf7.jpg
IB BIO – 1.1 This method can also be used to calculate the size of structures in
79
S1: Calculation
of the given scale length = actual size
magnification of
drawings and measured length of scale size in image
the actual size
of structures
and
ultrastructures. or..
Guidance
actual size = size in image
G3 Scale bars
are useful as a magnfication
way of
indicating actual
sizes in
drawings and
micrographs.
IB BIO – 1.1 Practice: How long is the cell shown in the image below?
80
Skills
S1: Calculation
of the
magnification of
drawings and
the actual size
of structures
and
ultrastructures.
Guidance
G3 Scale bars
are useful as a
way of
indicating actual
sizes in
drawings and 10 µm
micrographs.
http://slideplayer.com/13/4088643/big_thumb.jpg
IB BIO – 1.1 If a red blood cell has a diameter of 8 mm and a student 81
A. × 0.0002
B. × 0.2
C. × 5
D. × 5000