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Medical Application

This document discusses several medical applications of recombinant DNA (rDNA) technology: 1) The mass production of antibiotics like penicillin and streptomycin through genetically engineered fungi. 2) The large-scale production of insulin through incorporation of the human insulin gene into bacteria. 3) The production of vaccines by transferring antigen genes into bacteria to provide protection against infection. 4) The production of interferons, which are antiviral proteins, through recombinant DNA techniques to treat cancers and viral infections.

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Ela Morillo
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60 views20 pages

Medical Application

This document discusses several medical applications of recombinant DNA (rDNA) technology: 1) The mass production of antibiotics like penicillin and streptomycin through genetically engineered fungi. 2) The large-scale production of insulin through incorporation of the human insulin gene into bacteria. 3) The production of vaccines by transferring antigen genes into bacteria to provide protection against infection. 4) The production of interferons, which are antiviral proteins, through recombinant DNA techniques to treat cancers and viral infections.

Uploaded by

Ela Morillo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Medical Application

General Biology 2
2

Recombinant DNA (rDNA)


has many uses in the society
of today, from research and
biotechnology to the
medicine stocked on the
shelves of pharmacies.
3

1
Production of
antibiotics
4

Penicillium and Streptomyces


fungi are used for mass production
of famous antibiotics penicillin
and streptomycin. Genetically
efficient strains of these fungi have
been developed to greatly increase
the yield of these antibiotics.
5

2
Production of
hormone insulin
Human gene for insulin 6

production has been


incorporated into bacterial
DNA and such genetically
engineered bacteria are
used for large-scale
production of insulin.
7

3
Production of
vaccines
8

Vaccines are now produced


by transfer of antigen-coding
genes to disease-causing
bacteria. Such antibodies
provide protection against the
infection by the same bacteria
or virus
9

4
Production of
interferon
10

Interferons are virus-induced


proteins produced by virus-infected
cells. They are antiviral in action and
act as first line of defense against
viruses causing infections, including
breast cancer and lymph node
malignancy. Natural interferon is
produced in very small quality from
human blood cells.
11

5
Production of
enzymes
12

Some useful enzymes can also be


produced by recombinant
DNA technique.
13

6
Gene Therapy
14

Genetic Engineering enable to


replace the defective genes
responsible for hereditary
diseases with normal genes.
15

7
Solution of disputed
parentage
16

Disputed cases of parentage


can now be solved most
accurately by recombinant
technology than by blood
test.
17

8
Diagnosis of disease
18

Recombinant DNA technology


has provided a broad range of
tools to help physicians in the
diagnosis of diseases. By testing
the DNA of prospective genetic
disorder carrier parents, their
genotype can be determined and
their chances of producing an
afflicted child can be predicted.
19

9
Production of
transgenic animals
20

Animals which carry foreign


genes are called transgenic
animals.

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