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The document discusses various ocular manifestations that can occur in patients with HIV/AIDS, including cytomegalovirus retinitis, immune recovery uveitis, retinal detachment, necrotizing herpetic retinitis, toxoplasmosis retinochoroiditis, ocular syphilis, and others. It also covers external manifestations such as Kaposi sarcoma, molluscum contagiosum, herpes zoster ophthalmicus, and keratitis. Many of these conditions are sight-threatening and more common in patients with advanced AIDS and low CD4 counts. The document provides details on presentation, diagnosis, and treatment of these ocular manifestations.

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Usamah Haidar
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26 views44 pages

Add Slide

The document discusses various ocular manifestations that can occur in patients with HIV/AIDS, including cytomegalovirus retinitis, immune recovery uveitis, retinal detachment, necrotizing herpetic retinitis, toxoplasmosis retinochoroiditis, ocular syphilis, and others. It also covers external manifestations such as Kaposi sarcoma, molluscum contagiosum, herpes zoster ophthalmicus, and keratitis. Many of these conditions are sight-threatening and more common in patients with advanced AIDS and low CD4 counts. The document provides details on presentation, diagnosis, and treatment of these ocular manifestations.

Uploaded by

Usamah Haidar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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Dry eye and HIV/AIDS

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205170/#B2
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164028
Dry eye and HIV/AIDS

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205170/#B2
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164028
CMV Retinitis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636133
Terapi CMV Retintis (AAO)
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Zona Retintis
Terapi CMV
Immune recovery uveitis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Raosoft sample size calculator

http://www.raosoft.com/samplesize.html
Uji Korelasi

Dahlan, MS. Statistik untuk Kedokteran dan Kesehatan. Jakarta: Epidemiologi Indonesia.
Stage HIV/AIDS

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536229
Stadium HIV/AIDS
Viral Load
& CD4
CD4 Baseline & Ocular Manifest

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
HIV Retinopathy

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Cytomegalovirus Retinitis
Disseminated CMV infection  most common opportunistic infection in people with AIDS.
Retinal infection  most clinically important manifestation occurring in up to 40% of patients with AIDS,
usually those with CD4+ T- lymphocyte counts less than 50 cells/µL.

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Cytomegalovirus Retinitis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Immune recovery uveitis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Retinal detachment

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Necrotizing Herpetic Retinitis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Toxoplasma Retinochoroiditis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Toxoplasma Retinochoroiditis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Ocular Syphilis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Multifocal Choroiditis and
Systemic Dissemination

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Pneumocystis jirovecii choroiditis

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Cryptococcosis

Figure 13-7 Cryptococcal choroiditis. Fundus photograph


(A) and fundus autofluorescence image (B) show multifocal chorioretinal lesions.

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
External Eye Manifestations
• Other ophthalmic conditions associated with infection that occur in
persons with AIDS include:
• Kaposi sarcoma
• Molluscum contagiosum
• Herpes zoster ophthalmicus
• Keratitis  due to various viral or protozoal infections, conjunctival
infections, and microvascular abnormalities.

All of these conditions affect mainly the anterior segment of the globe and
the ocular adnexa.
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Kaposi sarcoma

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Molluscum contagiosum

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Herpes zoster ophthalmicus

American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
American Academy of Ophthalmology. Uveitis and Ocular Inflammation. In: Smith WM, Armbrust KR, Dahr SS, Dodds EM, et al.,
editors. Basic and Clinical Science Course. Section 9. San Fransisco: American Academy of Ophthalmology. 2023.
Neoplasma and HIV
PORN
ARN
Uveitis pada HIV AIDS

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