Project work presentation
Formulation and evaluation of Gel based Sunscreen with kojic acid
Submitted by- Submitted to-
Shiv Parkash Mr. Amanpreet Singh
University roll no. 2123019 Assistant Professor
FACULTY OF PHARMACEUTICAL SCIENCE
PCTE GROUP OF INSTITUTES
Table of contents
Introduction
Project objective and scope
Literature review
Proecdure
Evaluation Parameters
Conclusion
References
Introduction
• Sunscreen protect skin from UV rays.
• Prevent sun burn.
• Prevent premature aging.
• Reduce risk of skin cancer.
Project objective
• To Prepare hybrid sunscreen in Gel base.
• To prepare sunscreen which also treat hyperpigmentation and sun damage.
• To provide Broad spectrum protection.
Literature Review
Article/Journal title Authors name Publishing year Aim to study
Formulation and evaluation Ms. Indira solai et al. 2019 To study about evaluation
of sunscreen parameters for sunscreen
Overview: Application of Ms. Safitri et al. 2021 To study about uses &
carbopol 940 in Gel properties of carbopol 940.
Review on sunscreen and Sudhahar et al. 2015 To study about the SPF
sun protection factor
Formulation and evaluation Ms. Rina et al. 2019 To study about the
of gel based sunscreen formulation of gel based
sunscreen
Zinc oxide nanoparticles in Megan et al. 2010 To study about use of zinc
modern sunscreen oxide in sunscreen
Article/Journal title Authors name Publishing year Aim to study
Sunscreen emulsion with Moyal D et al. 2016 To study about different
broad spectrum UV filters UV filters for sunscreen
Protective Effect of citrus Catrula N et al. 2014 To study about use and
and Rosemary extract on effect of Rosemary in
UV induced damage in sunscreen
skin cell
Review on skin lightening Dwivedi A. K et al. 2023 To study about use of
agents kojic acid
Formulation Table
Ingredients F1 F2 F3
Avobenzone 1.5g 1.5g 1.5g
Zinc oxide 2.5g 2.5g 2.5g
Rosemary extract 1.5g 1.5g 1.5g
Caprylic acid 2.5g 3.5g 5g
Glycerine 1ml 2.5ml 5ml
Propylene glycol 1ml 2.5ml 5ml
Stearic acid 1.5g 2g 3g
Cetyl alcohol 1.5g 2g 3g
Carbopol940 0.5g 0.5g 0.5g
Kojic acid 1g 1g 1g
Triethanolamine 1ml 1ml 1ml
Phenoxyethanol 0.5ml 0.5ml 0.5ml
Fragrance 2-3 drops 2-3drops 2-3drops
Distilled water Q. S Q. S Q. S
Formulation method
Evaluation parameters
• Physical Parameters
• pH
• Viscosity
• Skin irritation
• Spreadability
• SPF
Brookfield
Spectrophotometer
viscometer
Evaluation Parameters F3
Colour Whitish yellow
Odor Rose like
Texture Smooth
pH 5.7
Viscosity 9766cps
Spreadability Good
Irritancy test No irritation
SPF 35
Stability No separation
References
Kaimal S, Abraham A. Sunscreens. Indian J Dermatol Venereol Leprol 2011;77:238-43.
• Parwaiz, Shaikh & Khan, Mohammad Mansoob. (2023). Recent developments in tuning
the efficacy of different types of sunscreens. Bioprocess and Biosystems Engineering. 46.
3. 10.1007/s00449-023-02919-9.
• Dwivedi, A. K. A Review on natural skin lightening agent,Innovare journal of health
Sciences October 2023).
• National Center for Biotechnology Information (2024). PubChem Compound Summary
for CID 51040, Avobenzone. Retrieved November 17, 2024 from
https://pubchem.ncbi.nlm.nih.gov/compound/Avobenzone.
• Osmond-McLeod, Megan & McCall, Maxine. (2010). Zinc oxide nanoparticles in modern
sunscreens: An analysis of potential exposure and hazard. Nanotoxicology. 4. 15-41.
10.3109/17435390903502028.
• Li Pomi F, Papa V, Borgia F, et al. Rosmarinus officinalis and Skin: Antioxidant Activity
and Possible Therapeutical Role in Cutaneous Diseases. Antioxidants (Basel).
2023;12(3):680. Published 2023 Mar 9.
• Rina, Aprilita & Eff, Yanti & Rahayu, Sri & Saraswati, Henny & Mun'im, Abdul.
(2019). Formulation and Evaluation of Sunscreen Gel, 141-145.
• T. Muthumani, V. Sudhahar, T. Mukhopadhyay. Review on Sunscreens and Sun
Protection factor. Research J. Topical and Cosmetic Sci. 6(2): July-Dec. 2015 page 55-
65
• Safitri, Fenny & Nawangsari, Desy & Febrina, Dina. (2021). Overview: Application of
Carbopol 940 in Gel. 10.2991/ahsr.k.210127.018.
• Saeedi, M., Eslamifar, M., & Khezri, K. (2018). Kojic acid applications in cosmetic and
pharmaceutical preparations. Biomedicine & Pharmacotherapy, 110, 582–593.
• Jesus A, Augusto I, Duarte J, Sousa E, Cidade H, Cruz MT, Lobo JMS, Almeida IF.
Recent Trends on UV filters. Applied Sciences. 2022; 12(23)
• Andersen, F. A. (2013). Safety Assessment of Triethanolamine and
Triethanolamine-Containing Ingredients as Used in Cosmetics. International
Journal of Toxicology, 32, 59S-83S.
• Pérez-Sánchez A, Barrajón-Catalán E, Caturla N, et al. Protective effects of citrus
and rosemary extracts on UV-induced damage in skin cell model and human
volunteers. J Photochem Photobiol B. 2014;136:12-18.
• Moyal, D. (2016). Sunscreen emulsions with broad-spectrum UV filters: UVB and
UVA protection. Journal of the American Academy of Dermatology, 75(3), S122-
S129.
THANK
YOU
