CSMU School of Pharmacy
What is
novel
drug
Presented by,
DRx.Prajakta Katekar
What is novel drug
Novel drug are often innovative product
that serve previously unmet medical
need or otherwise significantly help to
advance patient care and public health.
Novel drug delivery system is for delivery of drug other than
conventional drug delivery system.
NDDS refers to the approaches, formulations technolies and system for
transporting drug in the body as needed to safely achieve its desired
therapeutic effects.
Advantages Factor Affecting to
NDDS
NDDS includes optimum dose
at the right time and right • Physico-chemical properties
location efficient use of • Route of administration
expensive drug and excipients • Targeted sites
and reduction in production • Disease level.
cost, beneficial to patients
better therapy, improved
comfort and standard of living
Classification
1. Controlled release drug delivery system (CRDDS)
2. Micro-encapsulation
3. Muco-adhesive drug delivery system(MDDS)
4. Implantable drug delivery system (IDDS)
5. Transdermal drug delivery system (TDDS)
6. Gastro-retentive drug delivery system (GRDDS)
7. Naso-Pulmonary drug delivery system (NPDDS)
8. Targeted drug delivery system
9. Ocular drug delivery system (ODDS)
10. Intra-Uterine drug delivery system (IUD)
11. Vaginal drug delivery system (VDDS)
Controlled release drug delivery system (CRDDS)
Matrix diffusion type:
Dissolution matrix type
Encapsulation
Dissolution and diffusion controlled release system
Osmotic pressure Controlled system
Chemically ontrolled system
Hydro-gel
Ion exchange resins ontrolled release system
Micro-encapsulation
Micro-spheres
Microspheres are polymeric micron range spherical particles that can be used as drug carriers wherein the drug can be
encapsulated or is in entrapped form.
Micro-capsules
Microcapsules are small spheres with deposition of a thin polymer coating onto small solid particles or liquid droplets, or on
dispersion of solids in liquids.
Micro-particles
These are spherical particles of 1-1000um size that serve as multi-unit drug delivery system with well-defined physiological and
pharmaco-kinetic benefits in order to improve the effectiveness, tolerability and patient compliance