This document discusses principles for managing change in the 21st century. It begins by outlining tools and models that are now available but were not 17 years ago. It advocates moving beyond overly relying on single best practices from the 20th century. The document then presents five principles for introducing and developing Lean-Agile approaches in an organization: 1) Start with needs, 2) Agree on outcomes, 3) Keep the agenda for change visible, 4) Manage options and test assumptions, and 5) Organize for clarity, speed and mutual accountability.