Cholelithiasis is the presence of gallstones in the gallbladder. Gallstones can be cholesterol stones, pigment stones, or mixed stones. Risk factors include family history, older age, obesity, high-fat diet, and lack of exercise. Symptoms include pain in the upper right abdomen after eating fatty meals. Complications can include gallbladder inflammation, blocked bile ducts, or pancreatitis. Diagnosis involves ultrasound, CT scan, or blood tests. Treatment options are medical management to relieve pain, dissolution therapy, shockwave lithotripsy, or cholecystectomy to remove the gallbladder. Prevention focuses on a healthy diet and exercise.