This report outlines the economic opportunity of transitioning from a linear "take-make-dispose" economy to a circular economy where resources are reused and waste is designed out. It finds that adopting circular business models could result in annual net material cost savings of $380-630 billion for EU manufacturing sectors by 2025. Case studies show companies can benefit from designing products for disassembly, reuse, remanufacturing and recycling to reduce costs while increasing value creation. The report argues the circular economy presents a solution to risks of resource scarcity and volatility, and a way for businesses to decouple revenues from material inputs through more sustainable models.