This document discusses sudden cardiac death (SCD) in young athletes. SCD is the leading cause of death in exercising young athletes, with estimates of incidence ranging from 1 in a million to as high as 1 in 3,000 for some athlete populations. SCD often results from structural heart abnormalities that may be detected through pre-participation physicals. Pre-participation cardiovascular screening evaluates large athlete populations before participation to reduce the risk of SCD. The document goes on to discuss recommendations and components of pre-participation cardiovascular screening examinations.