Greyhound Chromatography Q - Fil Syringe Filters 2020

FilFil
Simply Quality
Greyhound Q-Fil Syringe Filters
YOUR GLOBAL SCIENCE PARTNER

RangeRange
As a trusted name in the supply of chromatography
consumables and certified reference standards, Greyhound also
offers a comprehensive selection of top quality own brand
Capillary columns and HPLC columns. This catalogue contains
details of the Q-Fil range of Syringe Filters. Other product
catalogues are available on request.
These quality products are backed by the guaranteed reliability
and technical support which has become synonymous with the
name Greyhound.
Visit our website at: www.greyhoundchrom.com for details of
our full range of products.
Welcome to a new era in analyte detection and
column performance.
Greyhound
Your Global Science Partner
Q-Fil Syringe Filters set the new Quality standard for today’s
laboratory syringe filters. Manufactured from the highest quality
medical grade, high density polypropylene. Q-Fil Syringe Filters
provide excellent chemical compatibility with acids, alcohols,
bases, ethers, glycols, ketones and oils.
Every colour-coded filter is printed with details of the membrane
material and its pore size on the outside of the filter and every
box is labelled with the batch number making them ideal for
traceability, GLPs and validation purposes.
Greyhound Q-Fil Syringe
Filters
Q-Fil Syringe Filters
Q-Cap Capillary Columns
Q-Col HPLC Columns
GC Septa and Ferrules
FilFil
SYRINGE FILTERS BY GREYHOUND
Certificate of Conformance • Disposable Syringe Filters
Greyhound Chromatography and Allied Chemicals
6 Kelvin Park Birkenhead Merseyside CH41 1LT England
Tel: +44 (0) 151 649 4000 Fax: +44-(0) 151 649 4001
Email: info@greyhoundchrom.com Web: www.greyhoundchrom.com
This product complies with all Q-Fil Syringe Filter manufacturing specifications and was
produced in accordance with ISO 9001 Quality Management System
Product Q-Fil Syringe Filter
Part Number 40-100001
Lot Number SM280616
Filter Material Hydrophilic Nylon 0.45µm
Housing Material Polypropylene
Membrane Diameter 25mm
Test Specifications
Visual Inspection Absence of External defects
Luer Lock Female Luer-Lock Inlet, Male
Slip Outlet
Bubble Point 29 psi
Burst Pressure 87 psi
Filtration Area 4.08 cm3
Holdup Volume <100μL
Volume Throughput 100mL
Q-Fil Certificate of Conformance

GREYHOUND Q-Fil SYRINGE FILTERS
1
Why filter your
samples for
HPLC?
The main source of particle contamination in HPLC columns originate in the sample to be analysed.
Therefore, the final preparation step prior to sample injection into the HPLC instrument is to remove any small
particulates from the sample by filtration. Removal of the solid materials is very important as they can interfere
with the compound of interest and easily clog up the column being used. This will inevitably have a
detrimental effect on the performance of the column, i.e. back pressure, peak size, retention time, peak shape.
Severe contamination can lead to the column being irreversibly blocked and therefore having to be replaced.
Other costs can include instrument downtime, and the loss of valuable samples.
Sample Types
Samples differ in a variety of ways, they may be heavily loaded with fine or coarse particulates, dissolved in
aqueous or organic solvents with varying viscosities. To facilitate the most appropriate sample preparation
result, filters should be optimised to match the particular requirements of each kind of sample being injected.
Standard Samples
A matrix of 5-10mL is the most common sample volume, with low viscosity, low particle contamination and
dissolved in either an organic or an aqueous solvent. Greyhound Q-Fil Regenerated Cellulose Syringe Filters
are an excellent choice for such samples. Their inert housing manufactured from high density medical grade
virgin polypropylene, complete with the integrated Regenerated Cellulose (RC) membrane has a high chemical
resistance against the most common HPLC solvents and is very suitable for aqueous samples. Every batch
is HPLC-tested for low extractables. Whilst 0.45µm is the most commonly used membrane porosity, the
0.22µm membrane provides improved purity when using capillary columns or HPLC packings with a
particle size of 3µm or less
Demanding Samples
More difficult samples which contain high loads of particulates, high viscosity or unusually high volumes
place additional challenges on the user when preparing samples for HPLC analysis. The particles have a
tendency to block the filter, high viscosities will decrease the flow rate and high volumes increase the time
required to complete the filtration process. These challenges often result in the user applying a greater degree
of manual pressure to the process and potentially exceeding the maximum pressure limit of the filter with a
subsequent risk of bursting the housing. As a result, the sample will be lost and a potential safety risk can
arise if corrosive solvents or harmful chemicals are being filtered. To assist in overcoming these challenges,
the use of Q-Fil Syringe Filters with a built in Glass Microfiber pre-filter are recommended. The pre-filter
removes the larger particulates from the sample leaving only the smaller particulates to be filtered by the
membrane. These filters increase the flow rate through the unit resulting in a higher volume of sample to be
filtered and less pressure being required by the user.
Small Volume Samples
Smaller volume samples are often valuable and require special attention. Any loss of the analyte due to
adsorption by the filter membrane or housing or a large dead volume can have a detrimental effect on the
analysis. Smaller filters of 13mm and 4mm diameter decrease the dead volume to less than 25uL and 8uL
respectively making them ideal for smaller volume samples.
Summary
Sample filtration is an important factor in ensuring that HPLC analysis is achieved in an efficient and cost
effective way. The extensive range of Q-Fil Syringe Filters have been developed to meet the demands of the
analyst and the different sample matrices being used and without losing any of the important sample.
Why use
Greyhound
Q-Fil Syringe
Filters?
• Every batch of filters is manufactured and tested in accordance with strict ISO 9001:2015 quality procedures
• Every individual Q-Fil Syringe Filter is visually inspected to ensure it meets our manufacturing and quality
control specifications
• Each batch of filters is tested prior to release for:
- External Dimensions - Bubble Point - Water Flow Rate - UV Extractables
- Burst Pressure and compliance - Filter Integrity
About our
Quality Control
procedures
• Every box is supplied with a Certificate of Conformance to guarantee its batch to batch quality
and performance
• The unique encapsulating process developed for these filters, forces the sample to pass only through the
membrane, thus avoiding the possibility of leaks or contamination
• Available in the most popular sizes, porosities and membrane types
• Excellent resistance to all routinely used HPLC solvents
• Filter housings are manufactured from the highest quality medical grade, high density polypropylene
• Extremely low level of extractables for highly sensitive work
• Luer connections fully comply with ISO 594-1

30mm Dia
25mm Dia
13mm Dia
4mm Dia
2
Designed for the largest sample volumes or solvent filtration
Filtration area 5.39cm2
Maximum filtration volume <200ml
Maximum operating pressure 87psi (6.0 bar) at 20°C
Sample volume <200ml
Holdup volume <200µl
Designed for larger sample volumes or solvent filtration
Maximum filtration volume >100ml
Sample volume <100ml
Suitable for most applications
Maximum filtration volume >10ml
Sample volume <10ml
Suitable for smaller volume applications
Maximum filtration volume <2ml
Sample volume <2ml
Holdup volume <8ul
• Choose the size of filter based on the volume of sample to be filtered
• Choose the filters porosity based on the size of the potential particulates in the sample. It is important to be
aware that the finer the porosity of the membrane the greater the pressure will be required to pass the sample
through the filter. A sample containing large quantities of particulates is best filtered using a filter with a built-in
glass microfiber pre-filter
• Choose the type of membrane based on the solvent being filtered
Selecting the
right Q-Fil
Syringe Filter

4
Syringe Filter Membrane Compatibility Chart
Chemical Nylon PTFE PVDF PES CA RC PP GMF
ACIDS
Acetic, Glacial LC C C C IC C C C
Acetic, 25% C C C C CA C C C
Hydrochloric, Concentrated IC C C C IC IC C C
Hydrochloric, 25% IC C C C IC IC C C
Sulphuric, Concentrated IC C IC IC IC IC C C
Sulphuric, 25% IC C C C IC LC C C
Nitric, Concentrated IC C C IC IC IC C LC
Nitric, 25% IC C C C IC IC C LC
Phosphoric, 25% IC C ND ND CA LC C ND
Formic, 25% IC C ND ND LC C C C
Trichloroacetic, 10% IC C ND ND CA C C ND
ALCOHOLS
Methanol, 98% C C C C C C C C
Ethanol, 98% C C C C C C C C
Ethanol, 70% IC C C C C C C C
Isopropanol C C C C C C C C
n-Propanol C C C C C C C C
Amyl Alcohol (Butanol) C C C C C C C C
Benzyl Alcohol C C C ND LC C C IC
Ethylene Glycol C C C C C C C C
Propylene Glycol C C C C LC C C C
Clycerol C C C C C C C C
ALKALIS
Ammonium Hydroxide, 25% C C LC C C LC C C
Sodium Hydroxide, 3N C C C C IC LC C IC
AMINES AND AMIDES
Dimethyl Formamide LC C IC IC IC LC C C
Diethylacetamide C C ND ND IC C ND C
Triethanolamine C C ND ND C C ND ND
Aniline ND C ND ND IC C ND ND
Pyridine C C IC IC IC C IC C
Acetonitrile C C C LC IC C C C
ESTERS
Ethyl Acetate/Methyl Acetate C C C IC IC C LC C
Amyl Acetate/Butyl Acetate C C IC IC LC C LC C
Propyl Acetate C C IC IC LC C LC ND
Propylene Glycol Acetate ND C ND IC IC C C ND
2-Ethoxyethyl Acetate ND C ND IC LC C ND ND
Methyl Cellusolve ND C ND IC IC C C C
Use this information to determine the ability of a specific syringe filter membrane to withstand exposure to solvent.
All concentrations are 100% unless noted.

5
Chemical Nylon PTFE PVDF PES CA RC PP GMF
ESTERS
Benzyl Benzoate C C ND IC C C ND ND
Isopropyl Myristate C C ND IC C C ND ND
Tricresyl Phosphate ND C ND IC C C ND ND
HALOGENATED HYDROCARBONS
Methylene Chloride LC C C IC IC C LC C
Chloroform C C C IC IC C LC C
Trichloroethylene C C C IC C C C C
Chlorobenzene C C C IC C C C C
Freon C C C IC C C C C
Carbon Tetrachloride C C C IC LC C LC C
HYDROCARBONS
Hexane/Xylene C C C IC C C IC C
Toluene/Benzene C C C IC C C IC C
Kerosene/Gasoline C C C LC C C LC ND
Tetralin/Decalin ND C C ND C C ND ND
KETONES
Acetone C C IC IC IC C C C
Cyclohexanone C C IC IC IC C C C
Methyl Ethyl Ketone C C IC IC LC C LC C
Isopropylacetone C C IC IC C C ND C
Methyl Isobutyl Ketone ND C IC IC ND C LC C
ORGANIC OXIDES
Ethyl Ether C C C C C C LC ND
Dioxane C C LC IC I C C C
Tetrahydrofuran C C LC IC I C C C
Triethanolamine C C ND ND C C ND ND
Dimethylsulfoxide (DMSO) C C IC IC I C C C
Isopropyl Ether ND C C C C C C ND
MISCELLANEOUS
Phenol,Aqueous Solution 10% ND C LC IC IC IC C C
Formaldehyde Aqueous C C C C C LC C C
Solution 30%
Hydrogen Peroxide 30% C C ND ND C C ND ND
Silicone Oil/Mineral Oil ND C C C C C C C
LEGEND
PVDF Polyvinylidene
PES Polyethersulfone
CA Cellulose Acetate
RC Regenerated Cellulose
PP Polypropylene
GMF Glass MicroFibre
C Compatible
LC Limited Compatibility (membrane
may swell and shrink)
IC Incompatible (not recommended)
ND No compatibility data currently available
PTFE Polytetrafluoroethylene (Teflon®)

6
NYLON
• Hydrophilic membrane
• Excellent for HPLC samples and general filtration
• Compatible with organic and aqueous liquids
• Good solvent resistance and high protein retention
• Strong mechanical stability
Not suitable for use with strong acids or bases, halogenated hydrocarbons or protein
Cat. No. Description Colour Pack
40-100007
40-100008
40-100004
40-100003
40-100002
40-100001
40-100006
40-100005
Nylon Syringe Filters, 0.22µm, 4mm Clear 100
Nylon Syringe Filters, 0.45µm, 4mm Clear 100
Nylon Syringe Filters, 0.22µm, 13mm Blue 100
40-100004-PF
40-100003-PF
40-100002-PF
40-100001-PF
40-100006-PF
40-100005-PF
Nylon Syringe Filters, 0.22µm, 13mm, with pre-filter Blue 100
40-100004-S
40-100003-S
40-100002-S
40-100001-S
40-100006-S
40-100005-S
Nylon Syringe Filters, 0.22µm, 13mm, Sterile Blue 100
Tel: +44(0)151 649 4000 • Fax: +44(0)151 649 4001 • www.greyhoundchrom.com

7
CELLULOSE ACETATE
• Ideal for aqueous based samples, tissue culture media filtration and sensitive
biological samples
• Very low protein binding membrane, lower than PVDF and PES membranes
• Lower chemical resistance than Regenerated Cellulose
Not suitable for use with organic solvents
40-100330
40-100331
40-100063
40-100062
40-100061
40-100060
40-100065
40-100064
Cellulose Acetate Syringe Filters, 0.22µm, 4mm Clear 100
Cellulose Acetate Syringe Filters, 0.45µm, 4mm Clear 100
Cellulose Acetate Syringe Filters, 0.22µm, 13mm Orange 100
40-100063-PF
40-100062-PF
40-100061-PF
40-100060-PF
40-100065-PF
40-100064-PF
40-100063-S
40-100062-S
40-100061-S
40-100060-S
40-100065-S
40-100064-S
Cellulose Acetate Syringe Filters, 0.22µm, 13mm, with pre-filter Orange 100
Cellulose Acetate Syringe Filters, 0.22µm, 13mm, Sterile Orange 100

8
PTFE (HYDROPHOBIC)
• Hydrophobic membrane resistant to strong acids, aggressive solvents,
alcohols, bases and aromatics
• Ideal for the filtration and degassing of chromatography solvents and
for extremely basic mobile phase solutions
• Very low extractables
• Mechanically strong
• Excellent thermal stability
40-100300
40-100301
40-100017
40-100016
40-100015
40-100014
40-100019
40-100018
PTFE Hydrophobic Syringe Filters, 0.22µm, 4mm Clear 100
PTFE Hydrophobic Syringe Filters, 0.45µm, 4mm Clear 100
PTFE Hydrophobic Syringe Filters, 0.22µm, 13mm Red 100
40-100017-PF
40-100016-PF
40-100015-PF
40-100014-PF
40-100019-PF
40-100018-PF
PTFE Hydrophobic Syringe Filters, 0.22µm, 13mm, with pre-filter Red 100
40-100017-S
40-100016-S
40-100015-S
40-100014-S
40-100019-S
40-100018-S
PTFE Hydrophobic Syringe Filters, 0.22µm, 13mm, Sterile Red 100

PTFE (HYDROPHILIC)
• Hydrophilic membrane compatible with aqueous, organic solvents,
strong acids and alkalis
• Mechanically strong
• Excellent thermal stability
• Low protein binding
9
40-100310
40-100311
40-100312
40-100313
40-100314
40-100315
40-100316
40-100317
40-100312-PF
40-100313-PF
40-100314-PF
40-100315-PF
40-100316-PF
40-100317-PF
40-100312-S
40-100313-S
40-100314-S
40-100315-S
40-100316-S
40-100317-S
PTFE Hydrophilic Syringe Filters, 0.22µm, 4mm Clear 100
PTFE Hydrophilic Syringe Filters, 0.45µm, 4mm Clear 100
PTFE Hydrophilic Syringe Filters, 0.22µm, 13mm Red 100
PTFE Hydrophilic Syringe Filters, 0.22µm, 13mm, with pre-filter Red 100
PTFE Hydrophilic Syringe Filters, 0.22µm, 13mm, Sterile Red 100

10
PVDF (HYDROPHOBIC)
• Polyvinylidene difluoride membrane, hydrophobic
• Resistant to solvents, exhibits low levels of extractables
• Low protein binding membrane, can be used with proteins
and peptides
• Suitable for filtration of aqueous and organic solvents
• Ideal for HPLC and general biological filtration
40-100360
40-100361
40-100362
40-100363
40-100364
40-100365
40-100366
40-100367
40-100362-PF
40-100363-PF
40-100364-PF
40-100365-PF
40-100366-PF
40-100367-PF
40-100362-S
40-100363-S
40-100364-S
40-100365-S
40-100366-S
40-100367-S
PVDF Hydrophobic Syringe Filters, 0.22µm, 4mm Clear 100
PVDF Hydrophobic Syringe Filters, 0.45µm, 4mm Clear 100
PVDF Hydrophobic Syringe Filters, 0.22µm, 13mm Yellow 100
PVDF Hydrophobic Syringe Filters, 0.22µm, 13mm, with pre-filter Yellow 100
PVDF Hydrophobic Syringe Filters, 0.22µm, 13mm, Sterile Yellow 100

11
40-100320
40-100321
40-100033
40-100032
40-100031
40-100030
40-100035
40-100034
PVDF Hydrophilic Syringe Filters, 0.22µm, 4mm Clear 100
PVDF Hydrophilic Syringe Filters, 0.45µm, 4mm Clear 100
PVDF Hydrophilic Syringe Filters, 0.22µm, 13mm Yellow 100
40-100033-PF
40-100032-PF
40-100031-PF
40-100030-PF
40-100035-PF
40-100034-PF
40-100033-S
40-100032-S
40-100031-S
40-100030-S
40-100035-S
40-100034-S
PVDF Hydrophilic Syringe Filters, 0.22µm, 13mm, with pre-filter Yellow 100
PVDF Hydrophilic Syringe Filters, 0.22µm, 13mm, Sterile Yellow 100
PVDF (HYDROPHILIC)
• Modified Polyvinylidene difluoride membrane, hydrophilic
• Resistant to solvents, acids and chemicals
• Very low protein and preservative binding
• Clarification and purification of aqueous and organic solvents, acids and bases
• Filtration of antibiotics, diagnostics, serum, culture media and vaccines

12
POLYPROPYLENE
• Hydrophobic, high resistance to solvents
• Wide range of chemical compatibility to organic solvents
• Ideal for biological sample filtration
• Low protein binding
• Ideal for chromatography protein analysis and biological sample filtration
• Suitable for acids and bases and general HPLC analysis
40-100026
40-100027
40-100023
40-100022
40-100021
40-100020
40-100025
40-100024
Polypropylene Syringe Filters, 0.22µm, 4mm Purple 100
40-100023-S
40-100022-S
40-100021-S
40-100020-S
40-100025-S
40-100024-S
Polypropylene Syringe Filters, 0.22µm, 13mm, Sterile Purple 100

13
GREYHOUND Q-Fil SYRINGE FILTERSGREYHOUND Q-Fil SYRINGE FILTERS
POLYETHERSULFONE
• Very low protein and nucleotic acid binding
• Provides high flow rates and good throughput volume
• Best choice for tissue culture work
• Very low extractables
• Mechanically strong membrane, suitable for use with strong bases, alcohols
and resistive proteins
• Excellent flow rates
40-100340
40-100341
40-100053
40-100052
40-100051
40-100050
40-100055
40-100054
40-100053-PF
40-100052-PF
40-100051-PF
40-100050-PF
40-100055-PF
40-100054-PF
40-100053-S
40-100052-S
40-100051-S
40-100050-S
40-100055-S
40-100054-S
Polyethersulfone Syringe Filters, 0.22µm, 4mm Clear 100
Polyethersulfone Syringe Filters, 0.45µm, 4mm Clear 100
Polyethersulfone Syringe Filters, 0.22µm, 13mm Dark Green 100
Polyethersulfone Syringe Filters, 0.22µm, 13mm, with pre-filter Dark Green 100
Polyethersulfone Syringe Filters, 0.22µm, 13mm, Sterile Dark Green 100

14
REGENERATED CELLULOSE
• Hydrophilic, solvent resistant
• Very low protein binding
• Compatible with most common HPLC solvents
• Compatible with aqueous samples in pH range 3 to 12
• Suitable for biological samples and important for protein recuperation
• Best choice for low non-specific binding applications, tissue culture media filtration
and biological sample filtration
Not suitable for use with strong acids, chloroform or THF
40-100043
40-100042
40-100041
40-100040
40-100046
40-100045
Regenerated Cellulose Syringe Filters, 0.22µm, 13mm Light Blue 100
40-100043-PF
40-100042-PF
40-100041-PF
40-100040-PF
40-100046-PF
40-100045-PF
Regenerated Cellulose Syringe Filters, 0.22µm, 13mm, with pre-filter Light Blue 100
40-100043-S
40-100042-S
40-100041-S
40-100040-S
40-100046-S
40-100045-S
Regenerated Cellulose Syringe Filters, 0.22µm, 13mm, Sterile Light Blue 100

15
MIXED CELLULOSE ESTERS (MCE)
• A mixture of nitrocellulose and cellulose acetate
• Suitable for cleaning or sterilising many aqueous solutions
• Ideal for biological samples or culture media
40-100073
40-100072
40-100071
40-100070
40-100075
40-100074
Mixed Cellulose Ester (MCE) Syringe Filters, 0.22µm, 13mm Light Green 100
40-100073-PF
40-100072-PF
40-100071-PF
40-100070-PF
40-100075-PF
40-100074-PF
Mixed Cellulose Ester (MCE) Syringe Filters, 0.22µm, 13mm, with pre-filter Light Green 100
40-100073-S
40-100072-S
40-100071-S
40-100070-S
40-100075-S
40-100074-S
Mixed Cellulose Ester (MCE) Syringe Filters, 0.22µm, 13mm, Sterile Light Green 100

16
GLASS MICROFIBER (GMF)
• Commonly used as pre-filters to remove large particulates and extend
the loading capacity of the filter membrane
• Ideal for dissolution tests
40-100350
40-100351
40-100352
40-100353
40-100354
40-100355
40-100350-S
40-100351-S
40-100352-S
40-100353-S
40-100354-S
40-100355-S
Glass Fiber Syringe Filters, 0.7µm 13mm White 100
Glass Fiber Syringe Filters, 0.7µm 13mm, Sterile White 100

Greyhound Chromatography
and Allied Chemicals
6 Kelvin Park, Birkenhead,
Merseyside CH41 1LT
United Kingdom
Tel: (+44)-0-151 649 4000
Fax: (+44)-0-151 649 4001
www.greyhoundchrom.com
Greyhound Q-Fil
Syringe Filters
© Copyright Greyhound Chromatography & Allied Chemicals 2020. All rights reserved.

Greyhound Chromatography Q - Fil Syringe Filters 2020

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