Musculoskeletal System
Part 1.A: Skeletal System
Scope
I.
II.
III. Skeleton
Cartilage
Bone
A.Axial Skeleton
• Skull
•Vertebral Column
•Thoracic Cage
B. Appendicular Skeleton
•Pectoral (Upper limb)
•Pelvic (Lower
limb)Joints
CARTILAGE
Cartilage
•
•
•
•
Primarily made up of water
Contains no nerves or blood vessels
Special type of dense regular
connective tissue
Surrounded by:
•Perichondrium
Three Types of Cartilage
•Hyaline cartilage
•Flexibility and mobility
•Elastic cartilage
•Contains more stretchy elastic
fibers
• Fibrocartilage
•Highly compressible with great
tensile strength
Growth of Cartilage
•
•
•
Flexible matrix that can accommodate
mitosis
Grows in twoways.
Appositional growth -
>
cartilage-
forming cells secretes new matrix against
the external face of the existing cartilage
tissue
• Interstitial growth -> lacunae-bound
chondrocytes -> divide and secrete new
matrix,
within.
expanding the cartilage from
BONE
Bones
• Serves as:
•Support
• Protection
•Anchorage
•Mineral storage
•Blood cell formation
•Triglyceride (fat) storage
•Hormone production
Bones
• Classify by location
•Axial skeleton
•Appendicular skeleton
• Shape
•Long bones
•Short bones
•Sesamoid bones
•Flat bones
•Irregular bones
Gross Anatomy
Long Bone Anatomy
Bones
• Hematopoietic Tissue
• Red marrow
•
•
Infants: medullary cavity
Adults: long bones (red marrow
Yellow marrow)
à
Bone Markings
• provide a wealth of information about
howthe bone is attachedto muscles and
ligaments; worktogether
• Categories:
1.Projections that are sites of muscle
and ligament attachment
Bone Markings
• Categories:
1.Projections that are sites of muscle
and ligament attachment
2.Surfaces that form joints
Bone Markings
• Categories:
1.Projections that are sites of muscle
and ligament attachment
2.Surfaces that form joints
3. Depressions and openings for blood
vessels and nerves.
Microscopic Anatomy
BONE FORMATION
Bone Formation
•
•
Endochondral ossification
Intramembranous ossification
- bone develops by replacing hyaline cartilage
- bone develops from a fibrous membrane
Bone Formation -Endochondral ossification
A bone collar forms around the diaphysis of the
hyaline cartilage model
1.
Mesenchymal cells → Osteoblasts
→Osteoid → Collar
a.
Chondrocytes within the shaft hypertrophy
→ Primary Ossification center
b.
2. Cartilage calcifies in the center of the diaphysis
and then develops cavities
hypertrophied chondrocytes calcify →
chondrocytes die and the matrix begins to
deteriorates → Cavities
Bone Formation -Endochondral ossification
3.The periosteal bud invades the internal
cavities and spongy bone forms
• Cavities →invaded by collections
of elements (periosteal bud)
• Osteoclast partially erode cartilage
matrix → osteoid produced around
the calcified fragments → earliest
version of spongy bones
Bone Formation -Endochondral ossification
4. The diaphysis elongates and a medullary
cavity forms.
• primary ossification center enlarges,
osteoclasts break down the newly formed
spongy bone and open up a medullary cavity in
the center of the diaphysis
• secondary ossification centers develop in one
or both epiphyses
5. The epiphyses ossify
Bone Formation -Intramembranous ossification
4. Compact bone replaces
immature spongy bone, just
deep to the periosteum. Red
marrow develops.
Ossification centers develop in
the fibrous connective tissue
membrane
1.
2. Osteoid is secreted and calcifies.
3. Immature spongy bone and
periosteum form.
BONE REMODELLING
Bone remodeling
•
•Responds to:
Constituted by:
•
•
•
•
Resorption
Deposition
Hormones
Stress-sensing osteocytes
Bone remodeling –Resorption -PTH
Bone remodeling –Deposition
Controls
• Hormones
•
•
Parathyroid hormone
Calcitonin
Clinical Corner -Fractures
Describe the fracture A.
A.Incomplete, displaced,
open
B.Incomplete, displaced,
close
C.Incomplete,
nondisplaced, open
D.Incomplete,
nondisplaced, close
A
B
NORMAL for reference
Clinical Corner -Fractures
Incomplete Displaced
Closed / simple
NORMAL for reference
A
B
Describe the fracture B.
A.Complete, displaced,
open
B.Incomplete, displaced,
close
C.Incomplete, displaced,
open
D.Complete, displaced,
close
A
B
NORMAL for reference
A
B
Complete Displaced
Closed / simple
NORMAL for reference
Clinical Corner -Fractures
Incomplete Displaced
In depth presentation about the muscoskeletal system
Bone Remodeling
BONE DISORDERS
In depth presentation about the muscoskeletal system
Paget’s Disease
•
•
Excessive and haphazard bone deposit and resorption
Pagetic Bone → newly formed bone
Musculoskeletal System
Part 1.B: Skeletal System -Skeleton
Scope
I.
II.
III. Skeleton
Cartilage
Bone
A.Axial Skeleton
• Skull
•Vertebral Column
•Thoracic Cage
B. Appendicular Skeleton
•Pectoral (Upper limb)
•Pelvic (Lower
limb)Joints
SKELETON
AXIAL SKELETON
In depth presentation about the muscoskeletal system
Skull
• Consist of:
•
•
•
•
8 cranial bones / cranium
14 facial bones
Most are flat bones
All except Mandible is united by Sutures
Sagittal Suture
•
•
Cranial bones
Cranium
•
• Unpaired
8 cranial bones composed of:
•Paired
•
•
•
•
•
•
Parietal
Temporal
Frontal
Occipital
Sphenoid
Ethmoid
In depth presentation about the muscoskeletal system
•Facial Bones:
•
• Paired
14 bones
•Composed of:
•Unpaired
•
•
•
•
•
•
•
•
Mandible
Vomer
Maxillae
Zygomatic
Nasals
Lacrimals
Palatines
Inferior nasal conchae
VERTEBRAL COLUMN
In depth presentation about the muscoskeletal system
Five regions
•
•
•
•
•
Cervical –7 vertebrae
Thoracic –12 vertebrae
Lumbar –5 vertebrae
Sacrum -articulates with hip bone
Cocyx - terminus
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
APPENDICULAR SKELETON
PECTORAL / SHOULDER GIRDLE
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
UPPER LIMB
ARM
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
FOREARM
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
HAND
In depth presentation about the muscoskeletal system
PELVIC / HIP GIRDLE
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
LOWER LIMB
THIGH
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
LEG
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
FOOT
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system
In depth presentation about the muscoskeletal system

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