This sermon encourages believers to make their best effort in pursuing goals and overcoming challenges. It discusses how frustration may lead some to quit, but the Bible teaches believers to persist in doing good works. The sermon uses examples like Helen Keller to illustrate that goals can be achieved through determined effort over time, even in the face of setbacks. It urges listeners to stay calm and keep trying their best, with God's help, so as not to limit their potential. The overarching message is that anything is possible if one believes in God and continues making their best effort.