Non Migratory Bioactive Polymer
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This document discusses non-migratory bioactive polymers for food packaging. It provides examples of how bioactive peptides and antimicrobial peptides can be covalently linked to packaging polymers to inhibit microbial growth without migrating into the food. Specifically, it mentions how chitosan, UV-irradiated nylon, and nylon treated with laser can all exhibit antimicrobial properties through interactions with microbial membranes that disrupt permeability. Non-migratory bioactive polymers provide benefits like improved stability of bioactive compounds, regulatory advantages over food additives, and enabling minimally processed foods with a longer shelf life.
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Non Migratory Bioactive Polymer
- 1. NON MIGRATORY BIOACTIVE POLYMERS SUBMITTED TO: SUBMITTED BY: Ms. NEHA SINGH KUSH VERMA 15/PFT/001
- 2. INTRODUCTION • Non-migratory bioactive packaging is a novel form of active packaging. • It gives desirable biological response to food without the active component migrating from the packaging into the food.
- 3. • Bioactive peptides were covalently linked to the free terminus of the PEG chains. • Antibacterial activity was found for films treated with antimicrobial peptide. • No activity was found for lactase attached to PE films. • NMBP possess biological activity without the active components migrating from the polymer to the substrate. • Example: inhibition of microbial growth.
- 4. Types of Non-Migratory Bioactive Polymers Chitosan a) Possesses broad spectrum antimicrobial activity. b) Commercially available as an antifungal coating for fresh fruit. c) Chitosan is the deacetylated form of chitin. d) Effective against gram-positive and gram- negative bacteria.
- 5. Interaction b/w polycationic chitosan and anions Change in membrane permeability Bacterial outer membrane gets disrupted Leakage of glucose lactate dehydrogenase (+ve charge exist on amino group of C₂ below pH 6.3)
- 6. UV irradiated nylon a) The antimicrobial effect is strongly dependent on the UV wavelength used, the temperature and the composition. b) Example- poly-L-lysine c) Interaction with negatively charged microbial membranes leading to membrane disruption. PEG It posses antimicrobial activity only at high concentrations. It reduces the adhesion of proteins and cells to polymers.
- 7. Nylon Lazer treatment at 193nm Amides converted into amines and binds with polymer chain Interaction with –vely charged microbial membrane leads to membrane disruption Leakage of cellular constituents
- 8. APPLICATION • In-package processing. • Antimicrobial packaging . • Shelf life extension. • Intelligent Packaging.
- 9. ADVANTAGES 1. Technical benefits a) Improved stability and conc. of bioactive compounds and its effect at a specific area. b) Immobilization of bioactive compounds. c) Conc. Of bioactive molecules are higher on the surface of polymer and headspace.
- 10. 2. Regulatory advantages a) A/C to US regulation that there is negligible migration into a food product is not classified as a food additive. b) NMBP don’t need to meet food additive regulation.
- 11. 3. Marketting aspects a) It incorporates non migratory antimicrobials in packaging material. b) It provide minimally processed, preservative free food products. c) More demand.
- 12. 4. Food processor’s perspective a) More stable pdt. with longer shelf life. b) Using lactase-active packaging, milk could be packed off a normal production run and a lactose reduced product obtained after a short period of storage. Eg- lactose free milk. c) It has high cost and low sales volume.
- 13. THANK YOU