Oxygen therapy involves administering oxygen at concentrations greater than room air (21%) to treat or prevent hypoxia. There are various devices that deliver oxygen at different concentrations, including low flow devices like nasal cannulas (25-45% oxygen), reservoir systems like simple face masks (35-60% oxygen), and high flow devices like venturi masks that use air entrainment to deliver higher concentrations (35-40% oxygen). Proper nursing care is required to monitor patients receiving oxygen therapy and address any potential complications like oxygen toxicity from overexposure.