Best HIPAA Compliance Software in the USA
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Compare the Top HIPAA Compliance Software in the USA as of January 2026
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What is HIPAA Compliance Software in the USA?
HIPAA compliance software is designed to help organizations in the healthcare industry meet the requirements of the Health Insurance Portability and Accountability Act (HIPAA). These platforms provide tools to ensure that sensitive patient information is protected and that healthcare providers are compliant with HIPAA's privacy and security regulations. Features typically include secure data storage, encryption, access controls, audit trails, and risk assessments, helping organizations identify potential vulnerabilities and mitigate risks. HIPAA compliance software also helps with employee training, policy management, and reporting to ensure that organizations remain compliant during audits. By using this software, healthcare providers can reduce the risk of data breaches, avoid legal penalties, and ensure patient privacy. Compare and read user reviews of the best HIPAA Compliance software in the USA currently available using the table below. This list is updated regularly.
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1
Carbide
Carbide
Carbide simplifies HIPAA compliance for healthcare providers and business associates by embedding administrative, physical, and technical safeguards into a single, guided platform. We help you manage risk assessments, policy documentation, and employee training while automating the collection of evidence needed for compliance. Carbide Academy educates staff on PHI handling, and our integrations provide insight into access logs and cloud configurations. Expert support ensures your HIPAA program is effective, audit-ready, and built to scale.Starting Price: $7,500 annually -
2
Diplomat Managed File Transfer
Coviant Software
Diplomat MFT by Coviant Software is a secure, reliable managed file transfer solution designed to simplify and automate SFTP, FTPS, and HTTPS file transfers. Built for seamless integration, Diplomat MFT works across major cloud storage platforms, including AWS S3, Azure Blob, Google Cloud, Oracle Cloud, SharePoint, Dropbox, Box, and more. With over two decades of proven, breach-free performance, Diplomat MFT supports compliance with HIPAA, HITECH, GLBA, PCI/DSS, GDPR, and DORA. It features robust capabilities such as PGP encryption, multi-factor authentication, IP-based access rules, and built-in threat intelligence. If you're still relying on manual scripts or outdated FTP tools and you're concerned about audit failures, security gaps, or compliance risks, Diplomat MFT offers a scalable, secure solution you can trust. Start your free trial today.Starting Price: $1,149/year -
3
DriveStrike
DriveStrike
DriveStrike is easy to use, implement and manage. With DriveStrike you can execute secure remote wipe, remote lock, and remote locate commands on any platform. Integrated drive encryption support as well as mobile device management MDM for mobile platforms. Our professional support team is always available to answer your questions and help you install our services or manage your account and devices. Protecting your data and devices has never been easier or more cost effective. If you have questions or need help understanding how best to protect your data please contact us and we will gladly answer your questions. Protect your business with a device and data protection platform that keeps all devices safe with a single solution and Dashboard. Keep your Workstations, MacBooks, iPads, Smartphones, Tablets, Laptops safe, secure, and organized.Starting Price: $0.99 per month -
4
Safetica
Safetica
Safetica’s Intelligent Data Security protects sensitive data where teams work, using powerful AI to deliver contextual awareness, reduce false positives, and stop real threats without disrupting productivity. With Safetica, security teams can maintain visibility and control over sensitive data, stay ahead of insider risks, maintain compliance, and secure sensitive cloud-based data. ✔️ Data Protection: Classify, monitor and control sensitive data across devices and clouds in real time. ✔️ Insider Risk and User Behavior: Spot risky behavior, detect intent, and stop insider threats to stay ahead of the careless handling of sensitive data, compromised user accounts and malicious user activity. ✔️ Compliance and Data Discovery: Prove compliance with audit-ready reporting for data in use, in motion, and at rest. ✔️ Cloud Security: Protect Microsoft 365, cloud, and file-sharing platforms to secure sensitive cloud-based data. -
5
ADAudit Plus helps keep your Windows Server ecosystem secure and compliant by providing full visibility into all activities. ADAudit Plus provides a clear picture of all changes made to your AD resources including AD objects and their attributes, group policy, and more. AD auditing helps detect and respond to insider threat, privilege misuse, and other indicators of compromise, and in short, strengthens your organization's security posture. Gain granular visibility into everything that resides in AD, including objects such as users, computers, groups, OUs, GPOs, schema, and sites, along with their attributes. Audit user management actions including creation, deletion, password resets, and permission changes, along with details on who did what, when, and from where. Keep track of when users are added or removed from security and distribution groups to ensure that users have the bare minimum privileges.Starting Price: $595.00/year
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6
Ostendio
Ostendio
Ostendio is the only integrated security and risk management platform that leverages the strength of your greatest asset. Your people. Ostendio delivers an easy-to-use, cost-effective platform that allows you to assess risk, create and manage critical policies and procedures, educate and empower your people to be secure with security awareness training, and monitor continuous compliance across 250+ security frameworks. With deep customization, advanced intelligence, and flexible controls, you’re always audit-ready, always secure, and always able to take on what’s next. For more information about Ostendio, visit ostendio.com. -
7
Paubox
Paubox
Healthcare's simple, easy, and scalable way to email secure, HIPAA compliant patient information. Keeping patient data secure and remaining HIPAA compliant is a top concern for healthcare organizations, especially when it comes to email. Paubox Email Suite provides guaranteed encryption so you can rest assured your patient data is protected. Our HIPAA compliant email service removes the hassle of portals and passcodes by sending encrypted emails that can be read right in your recipient’s inbox. Healthcare email encryption is easy with our patented tools which integrate easily into your existing email system with no training necessary for employees. Paubox HIPAA compliant email service is designed to empower IT and simplify the process for end-users, making the frustrations and vulnerability of emailing PHI a thing of the past.Starting Price: $29/month -
8
Accountable
Accountable HQ
Accountable can supercharge your risk management and empower your team by simplifying the process of managing risk across all levels of your organization, become compliant with HIPAA, GDPR, CCPA and more privacy laws, and build trust with your customers and partners. Easily comply with global privacy laws such as HIPAA, GDPR, CPRA and more using Accountable's easy-to-use solution for privacy compliance. Manage risk by identifying and mitigating vulnerabilities by using Accountable's security risk and data protection impact assessments, giving you confidence in risk management. Monitor 3rd and 4th party vendor risk with ease with built in questionnaires and business agreement templates. The employee portal gives your team a way to stay up to date on security awareness and HIPAA training as well as the ability to review policies or report potential security issues. Share compliance, security, and privacy reports with those inside and outside your organization.Starting Price: $399.00/month -
9
SaltStack
SaltStack
SaltStack is an intelligent IT automation platform that can manage, secure, and optimize any infrastructure—on-prem, in the cloud, or at the edge. It’s built on a unique and powerful event-driven automation engine that detects events in any system and reacts intelligently to them, making it an extremely effective solution for managing large, complex environments. With the newly launched SecOps offering, SaltStack can detect security vulnerabilities and non-compliant, mis-configured systems. As soon as an issue is detected, this powerful automation helps you and your team remediate it, keeping your infrastructure securely configured, compliant, and up-to-date. The SecOps suite includes both Comply and Protect. Comply scans and remediates against CIS, DISA-STIG, NIST, PCI, HIPAA compliance standards. And Protect scans for vulnerabilities and patches and updates your operating systems. -
10
SanerNow
SecPod Technologies
SecPod SanerNow is the world's best unified endpoint security & management platform that powers IT/Security Teams automate cyber hygiene practices. It works on an intelligent agent-server model to execute effective endpoint management and security. It gives you accurate vulnerability management with scanning, detection, assessment, prioritization, and remediation capabilities. SanerNow is available on both cloud and on-premise, whose integrated patch management automates patching across all major OSs like Windows, MAC, Linux, and a vast collection of 3rd party software patches. What makes it unique? You can now access other salient features like security compliance management, IT asset management, endpoint management, software deployment, application & device control, and endpoint threat detection and response, all on a single platform. With SanerNow, you can remotely perform and automate these tasks to secure your systems from the emerging wave of cyberattacks.Starting Price: $50/year/device -
11
EnGuard
Enterprise Guardian
EnGuard offers HIPAA compliant email services designed for the healthcare industry.Starting Price: $15 per month -
12
Probely
Probely
Probely is a web vulnerability scanner for agile teams. It provides continuous scanning of web applications and lets you efficiently manage the lifecycle of the vulnerabilities found, in a sleek and intuitive web interface. It also provides simple instructions on how to fix the vulnerabilities (including snippets of code), and by using its full-featured API, it can be integrated into development processes (SDLC) and continuous integration pipelines (CI/CD), to automate security testing. Probely empowers developers to be more independent, solving the security teams' scaling problem, that is usually undersized when compared to development teams, by providing developers with a tool that makes them more independent when it comes to security testing, allowing security teams to focus on more important and critical activities. Probely covers OWASP TOP10 and thousands more and can be used to check specific PCI-DSS, ISO27001, HIPAA, and GDPR requirements.Starting Price: $49.00/month -
13
Cloudaware
Cloudaware
Cloudaware is a cloud management platform with such modules as CMDB, Change Management, Cost Management, Compliance Engine, Vulnerability Scanning, Intrusion Detection, Patching, Log Management, and Backup. Cloudaware is designed for enterprises that deploy workloads across multiple cloud providers and on-premises. Cloudaware integrates out-of-the-box with ServiceNow, New Relic, JIRA, Chef, Puppet, Ansible, and over 50 other products. Customers deploy Cloudaware to streamline their cloud-agnostic IT management processes, spending, compliance and security.Starting Price: $0.008/CI/month -
14
Send It Secure
Protected Trust
Send and receive secure emails that enable you to meet HIPAA & GLBA compliance standards. Protected Trust Email Encryption is now Send It Secure by Protected Trust. You may know us as Protected Trust Email Encryption, or perhaps just Protected Trust. As our email encryption product has grown and our company offerings have increased, we believe it is the right time to create a new brand for our email encryption product. Our new brand comes with the product the market has learned to trust, and we welcome an even better user experience and an improved product designed to meet your needs. We are recognized as one of the most powerful encryption solutions on the market for the secure exchange of confidential data. Your trust and protecting your data are our priority. We are excited to bring you our updated email encryption solution, Send It Secure by Protected Trust.Starting Price: $15 per month -
15
HIPAA One
Intraprise Health
Leveraging this new suite of integrated products, practices, clinics, healthcare organizations of all sizes can now holistically address security risk management and HIPAA compliance across the continuum of their health system or network. Pairing HIPAA One’s automated Security Risk Assessment software platform with Intraprise Health’s existing cybersecurity capabilities offers our customers a complete security and compliance solution, increasing our commitment to securing our customer’s data. To learn more about our full suite of software and services, visit our new home on Intraprise Health. Make us part of your team to stay up-to-date, automate compliance and most importantly, protect your client's information. Completely healthcare-focused, we provide cybersecurity advisory services and cloud-based software solutions to meet the pressing information security needs you face now and will face in the future.Starting Price: $99.99 per month -
16
Immuta
Immuta
Immuta is the market leader in secure Data Access, providing data teams one universal platform to control access to analytical data sets in the cloud. Only Immuta can automate access to data by discovering, securing, and monitoring data. Data-driven organizations around the world trust Immuta to speed time to data, safely share more data with more users, and mitigate the risk of data leaks and breaches. Founded in 2015, Immuta is headquartered in Boston, MA. Immuta is the fastest way for algorithm-driven enterprises to accelerate the development and control of machine learning and advanced analytics. The company's hyperscale data management platform provides data scientists with rapid, personalized data access to dramatically improve the creation, deployment and auditability of machine learning and AI. -
17
JupiterOne
JupiterOne
JupiterOne is a cyber asset analysis platform every modern security team needs to collect and transform asset data into actionable insights to secure their attack surface. JupiterOne was created to make security as simple as asking a question and getting the right answer back, with context, to make the right decision. With JupiterOne, organizations are able to see all asset data in a single place, improve confidence in choosing their priorities and optimize the deployment of their existing security infrastructure.Starting Price: $2000 per month -
18
CyberCompass
CyberCompass
We build Information Security, Privacy, and Compliance Programs to improve your cyber resilience – saving you and your organization time and money. CyberCompass is a cyber risk management consulting and software firm. We navigate organizations through the complexity of cybersecurity and compliance at half the cost of full-time employees. We design, create, implement, and maintain information security and compliance programs. We provide consulting services and a cloud-based GRC workflow automation platform to save our clients over 65% of the time to become and remain cybersecure and compliant. We provide expertise and support for the following standards and regulations – CCPA/ CPRA, CIS-18, CMMC 2.0, CPA, CTDPA, FTC Safeguards Rule, GDPR, GLBA, HIPAA, ISO-27001, NIST SP 800-171, NY DFS Reg 500, Singapore PDPA, SOC 2, TCPA, TPN, UCPA, VCDPA. We also provide third-party risk management within the CyberCompass platform.Starting Price: $5000/year -
19
PBHS SecureMail
PBHS
Achieve and maintain data privacy compliance. PBHS Secure Mail is a mature HIPAA encrypted messaging solution for doctors, dentists, hospitals and other healthcare providers. Compliancy made easy! There is no software to install, configure or maintain. PBHS Secure Mail works on any device, from any location. It’s simple to share. Documents, Radiographs, CT Scans, and Messages are organized and available to all colleagues working on a case. Account initiation is as simple as logging in with your ADA Membership ID. Our optional Outlook Plug-in enables users to send and receive messages directly via Microsoft Outlook on your PC. Treatment Letters and private communications that are delivered from your practice management software to Outlook are now encrypted. Radiographs that are delivered from your digital x-ray systems to Outlook are now encrypted. No need to change how you email your colleagues and patients. Continue to use Outlook without violating HIPAA.Starting Price: $10 per month per account -
20
LuxSci
Lux Scientiae
LuxSci provides HIPAA-compliant web and email communications services. LuxSci creates uniquely secure and customizable enterprise-grade environments and solutions that enable organizations to confidently meet their specific business and security needs at scale. LuxSci’s HIPAA-compliant email and web solutions are HITRUST certified and include: • Secure High Volume Sending for delivering massive volumes of transactional and marketing emails. • Secure SMTP Connector for encrypting outbound emails sent from Microsoft 365 and Google Workspace. • Secure Email Marketing platform for creating and sending marketing campaigns with ePHI. • Secure Email Hosting for reliable and secure day-to-day business email. • Fully managed Secure Web and Database Hosting for web applications that require compliance. • Secure Forms to safely collect and store sensitive information. LuxSci provides a full suite of secure technology for companies requiring compliant web and email services.Starting Price: $4 per/user/month -
21
MailHippo
MailHippo
HIPAA compliant email made easy and affordable. MailHippo is the easiest way to securely send and receive sensitive information and attachments by email. There's no setup or configuration required. Just sign up and start sending and receiving HIPAA-compliant emails right away. End-to-end encryption means your sensitive emails and attachments are always secure, both in transit and at rest. MailHippo works with your current email address, and with any email provider. MailHippo looks and works great on any smartphone or tablet. Get a unique link that empowers you to receive totally-secure emails from anyone. Get our HIPAA-compliant email platform with secure encrypted email messaging for FREE during our limited-time Beta program!Starting Price: $4.95 per month -
22
Polymer
Polymer Data Security
Polymer DLP is a comprehensive data governance and remediation platform that integrates with your SaaS applications. We use machine learning and natural language processing to automatically detect and stop sensitive information like PII or business-critical data from going to the wrong people in real time. In addition, we offer real time feedback and training to stop future incidents before they happen. Try for free today and set up a custom policy in minutes. Polymer is constantly expanding, currently we integrate with Slack, Google Drive, Microsoft Teams, One Drive, Bitbucket, Github and Box.Starting Price: $4/month/user -
23
Satori
Satori
Satori is a Data Security Platform (DSP) that enables self-service data and analytics. Unlike the traditional manual data access process, with Satori, users have a personal data portal where they can see all available datasets and gain immediate access to them. Satori’s DSP dynamically applies the appropriate security and access policies, and the users get secure data access in seconds instead of weeks. Satori’s comprehensive DSP manages access, permissions, security, and compliance policies - all from a single console. Satori continuously discovers sensitive data across data stores and dynamically tracks data usage while applying relevant security policies. Satori enables data teams to scale effective data usage across the organization while meeting all data security and compliance requirements. -
24
ManageEngine AD360
Zoho
AD360 is an integrated identity and access management (IAM) solution for managing user identities, governing access to resources, enforcing security, and ensuring compliance. From user provisioning, self-service password management, and Active Directory change monitoring, to single sign-on (SSO) for enterprise applications, AD360 helps you perform all your IAM tasks with a simple, easy-to-use interface. AD360 provides all these functionalities for Windows Active Directory, Exchange Servers, and Office 365. With AD360, you can just choose the modules you need and start addressing IAM challenges across on-premises, cloud, and hybrid environments from within a single console. Easily provision, modify, and deprovision accounts and mailboxes for multiple users at once across AD, Exchange servers, Office 365 services, and G Suite from a single console. Use customizable user creation templates and import data from CSV to bulk provision user accounts.Starting Price: $595.00 / year -
25
Pryv.io
Pryv
Personal Data & Privacy Management Software - A ready-to-use solution for personal data and consent management. - Pryv.io is a solid foundation on which you build your own digital health solution, so you can collect, store, share and rightfully use personal data. - Maintained and developed by Pryv. Features - Provides latest Pryv.io core system ready for production - User registration and authentication - Granular consent-based access control rights - Data model made for privacy, aggregation and sharing - Full data life-cycle: collect - store - change - delete - REST & Socket.io API - Ease of software integration and configuration - Seamless connectivity and interoperability -
26
Hushmail
Hushmail
Hushmail protects your clients by adding encryption to your emails, web forms and e-signatures. It’s secure, HIPAA-compliant, and trusted by healthcare professionals worldwide. Best of all, Hushmail is easy to set up and use. Send your first encrypted email today, and set up a secure online intake form in minutes. Your Hushmail account works just like a regular email account, with added security features to help keep your data safe. Send and receive encrypted email on the web and iPhone. Access your account using Outlook, Apple Mail or your Android smartphone. Move your forms online in minutes. Hush™ Secure Forms is our secure alternative to old-fashioned paper forms and includes online signing for your most important digital forms. Switching from pen and ink to e-signatures has never been easier.Starting Price: $9.99/month/user -
27
Protegrity
Protegrity
Our platform allows businesses to use data—including its application in advanced analytics, machine learning, and AI—to do great things without worrying about putting customers, employees, or intellectual property at risk. The Protegrity Data Protection Platform doesn't just secure data—it simultaneously classifies and discovers data while protecting it. You can't protect what you don't know you have. Our platform first classifies data, allowing users to categorize the type of data that can mostly be in the public domain. With those classifications established, the platform then leverages machine learning algorithms to discover that type of data. Classification and discovery finds the data that needs to be protected. Whether encrypting, tokenizing, or applying privacy methods, the platform secures the data behind the many operational systems that drive the day-to-day functions of business, as well as the analytical systems behind decision-making. -
28
Runecast
Runecast Solutions
Runecast is an enterprise CNAPP platform that saves your Security and Operations teams time and resources by enabling a proactive approach to ITOM, CSPM, and compliance. It automates vulnerability assessment, configuration drift management and continuous compliance – for VMware, Cloud and Containers. By proactively using our agentless scanning in real-time admins discover potential risks and remediation solutions before any issues can develop into a major outage. It provides continuous audits against vendor best practices, common security standards, and frameworks such as BSI IT-Grundschutz, CIS, Cyber Essentials, DISA STIG, DORA, Essential 8, GDPR, HIPAA, ISO 27001, KVKK, NIST, PCI DSS, TISAX, VMware Security Hardening Guidelines, and the CISA KEVs catalog. Detect and assess risks and be fully compliant across your hybrid cloud in minutes. Runecast has been recognized with Frost & Sullivan's 2023 European New Product Innovation Award in the CNAPP industry. -
29
Virtru
Virtru
Easily control access to sensitive data flowing in and out of your organization via email, file sharing, and other applications. All powered by the Trusted Data Format and Virtru’s industry-leading platform for Zero Trust Data Control. Virtru integrates natively within the apps your teams already use, securing workflows in Google, Microsoft 365, Salesforce, Zendesk, and more. We make military-grade encryption accessible to everyone. Deploy Virtru across your organization in less than a day and meet your compliance goals. Granular access controls safeguard your most valuable asset — your data — throughout its entire lifecycle, everywhere it travels. Collaborate securely in Docs, Sheets, and Slides. Store and share files in Drive. Message via Gmail and Google Meet. Secure messages flowing through enterprise and custom apps. Seamlessly protect emails and files shared via Outlook. -
30
HushHush Data Masking
HushHush
Today’s businesses face significant punishment if they do not meet the ever-increasing privacy requirements of both regulators and the public. Vendors need to keep abreast by adding new algorithms to protect sensitive data such as PII and PHI. HushHush stays at the forefront of privacy protection (Patents: US9886593, US20150324607A1, US10339341) with its PII data discovery and anonymization tool workbench (also known as data de-identification, data masking, and obfuscation software). It helps you find your and your customer's sensitive data, classify it, anonymize it, and comply with GDPR, CCPA, HIPAA / HITECH, and GLBA requirements. Use a collection of rule-based atomic add-on anonymization components to configure comprehensive and secure data anonymization solutions. HushHush components are out-of-the box solutions designed to anonymize both direct identifiers (SSN, credit cards, names, addresses, phone numbers, etc.) as well as indirect identifiers, with both fixed algorithms.
