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Citicoline: Uses, Effects, and Dosage

Citicoline seems to increase levels of phosphatidylcholine in the brain which is important for brain function. It may also decrease brain tissue damage following injury. Citicoline taken by mouth or intravenously seems to improve memory and recovery from stroke and may improve symptoms of long-term cerebrovascular diseases. While some evidence suggests it may help cognitive function in Alzheimer's disease and vision problems in glaucoma, more evidence is needed to determine effectiveness for other conditions. Common side effects may include insomnia, headache, diarrhea and others. Safety of long-term use is unknown and it should be avoided during pregnancy and breastfeeding due to lack of information.

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Marianne Daphne Guevarra
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152 views3 pages

Citicoline: Uses, Effects, and Dosage

Citicoline seems to increase levels of phosphatidylcholine in the brain which is important for brain function. It may also decrease brain tissue damage following injury. Citicoline taken by mouth or intravenously seems to improve memory and recovery from stroke and may improve symptoms of long-term cerebrovascular diseases. While some evidence suggests it may help cognitive function in Alzheimer's disease and vision problems in glaucoma, more evidence is needed to determine effectiveness for other conditions. Common side effects may include insomnia, headache, diarrhea and others. Safety of long-term use is unknown and it should be avoided during pregnancy and breastfeeding due to lack of information.

Uploaded by

Marianne Daphne Guevarra
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd

CITICOLINE 5'-Cytidine diphosphate choline, CDPC, CDP Choline, CDP-Choline, Citicholine, Citicolina, Cytidine 5Diphosphocholine, Cytidine 5'-diphosphocholine, Cytidine

(5') diphosphocholine, Cytidine Diphosphate Choline, Cytidine Diphosphocholine, Cytidinediphosphocholine. MOA: Citicoline seems to increase a brain chemical called phosphatidylcholine. his brain chemical is important !or brain !"nction. Citicoline mi#ht also decrease brain tiss"e dama#e $hen the brain is in%"red. Possibly Effective for:

A#e-related memory problems. Citicoline seems to help memory loss in people a#ed 5& to '5 years. (tro)e reco*ery. (tro)e patients $ho ta)e citicoline by mo"th $ithin +, ho"rs o! ha*in# the )ind o! stro)e that is ca"sed by a clot (ischemic stro)e) are more li)ely than other ischemic stro)e patients to ha*e a complete reco*ery $ithin - months. .on#-term blood circ"lation problems in the brain (cerebro*asc"lar diseases). here is some e*idence that citicoline ta)en by mo"th or #i*en by /0 or as a shot mi#ht impro*e memory and beha*ior in patients $ith lon#-term cerebro*asc"lar diseases, s"ch as stro)e.

Insufficient Evidence for:

Al1heimer's disease and other types o! dementia. (ome e*idence s"##ests that ta)in# citicoline by mo"th mi#ht impro*e learnin#, memory and in!ormation processin# (co#niti*e !"nction) in people $ith mild to moderate Al1heimer's disease. Par)inson's disease. here is some e*idence that citicoline #i*en as a shot alon# $ith "s"al treatment mi#ht impro*e some o! the symptoms o! Par)inson2s disease, b"t not tremor. Attention de!icit-hyperacti*e disorder (AD3D). 4la"coma. De*elopin# e*idence s"##ests that citicoline mi#ht impro*e *isionin some people $ith #la"coma. 0asc"lar dementia. a)in# citicoline does not seem to impro*e symptoms in people $ith *asc"lar dementia. 3ead tra"ma. Other conditions. More e*idence is needed to rate the e!!ecti*eness o! citicoline !or these "ses. Citicoline seems to be sa!e $hen ta)en short-term ("p to 5& days). he sa!ety o! lon#-term "se is not )no$n. Most people $ho ta)e citicoline don't e6perience problematic side e!!ects. 7"t some people can

ha*e side e!!ects s"ch as tro"ble sleepin# (insomnia), headache, diarrhea, lo$ or hi#h blood press"re, na"sea, bl"rred *ision, chest pains, and others. Special Precautions & Warnings: Pregnancy and breast feeding: 8ot eno"#h is )no$n abo"t the "se o! citicoline d"rin# pre#nancy and breast-!eedin#. (tay on the sa!e side and a*oid "se. he !ollo$in# doses ha*e been st"died in scienti!ic research:

!" #O$T%: 9or decline in thin)in# s)ills d"e to a#e: :&&&-+&&& m# o! citicoline per day.

9or on#oin# disease o! the blood *essels that ser*e the brain (chronic cerebro*asc"lar disease): ;&& m# o! citicoline per day. 9or immediate treatment o! stro)e d"e to a clot (ischemic stro)e): 5&&-+&&& m# o! citicoline per day startin# $ithin +, ho"rs o! stro)e. INT&'(ENO$S: 3ealthcare pro*iders #i*e citicoline intra*eno"sly (by /0) !or a#e-related decline in thin)in# s)ills or !or chronic cerebro*asc"lar disease. !" IN)ECTION: 3ealthcare pro*iders #i*e citicoline by shot !or chronic cerebro*asc"lar disease.

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