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Drug Classificati ON Mechanism of Action Indications Contraindications Side Effects/ Adverse Effects Nursing Considerations

Cholestyramine and colesevalam are bile acid sequestrants used to treat hypercholesterolemia by binding bile acids in the gastrointestinal tract. This results in increased clearance of cholesterol from the body. Common side effects include constipation. Nursing considerations include assessing for contraindications and side effects, encouraging compliance with the regimen, and monitoring the patient's response to treatment.

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Franz Earl Niño Albesa
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351 views3 pages

Drug Classificati ON Mechanism of Action Indications Contraindications Side Effects/ Adverse Effects Nursing Considerations

Cholestyramine and colesevalam are bile acid sequestrants used to treat hypercholesterolemia by binding bile acids in the gastrointestinal tract. This results in increased clearance of cholesterol from the body. Common side effects include constipation. Nursing considerations include assessing for contraindications and side effects, encouraging compliance with the regimen, and monitoring the patient's response to treatment.

Uploaded by

Franz Earl Niño Albesa
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

DRUG MECHANISM INDICATIONS CONTRAINDICATIONS SIDE EFFECTS/ NURSING CONSIDERATIONS

CLASSIFICATI OF ACTION ADVERSE


ON EFFECTS
cholestyramine Binds bile acids in Management of - Hypersensitivity - Irritation of Assessment:
the GI tract, primary - Complete biliary the tongue - Assess for contraindications and
PO (adults): 4 forming an hypercholesterol obstruction - Abdominal cautions.
g1-2 times a daily insoluble complex. emia. Pruritis - Some products discomfort - Perform a physical assessment.
(initially, may be Result is increased associated with contain aspartame - Constipatio - Weigh the patient.
increased as clearance of elevated levels of and should be n - Inspect the patient’s skin for
needed/tolerated cholesterol. bile acids. avoided in patients - Nausea color, bruising, and rash.
up to 24g/day in 6 with - Flatulence - Assess neurological status.
divided doses) Therapeutic phenylketonuria. - Vomiting - Monitor pulse and blood
effects: - Rashes pressure.
PO (children): Decreased plasma
- Vitamin A,
240 mg/kg/day in cholesterol and Implementation:
D, and K
2-3 divided doses low-density - Do not administer powdered
deficiency
( not >8 g/day) lipoproteins. agents in dry form.
Decreased pruritis.
- If the patient is taking tablets,
ensure that tablets are not cut,
chewed, or crushed.
- measures.
- Offer support and
encouragement.
- Provide thorough patient teaching

Evaluation:
- Monitor patient response to the
drug.
- Monitor for adverse effects.
- Monitor for the effectiveness of
comfort measures and
compliance with the regimen.
DRUG MECHANISM INDICATIONS CONTRAINDICATIONS SIDE EFFECTS/ NURSING CONSIDERATIONS
CLASSIFICATION OF ACTION ADVERSE
EFFECTS
Colesevalam Binds bile acids Adjunctive therapy to - Hypersensitivity - Constipation Assessment:
in the GI tract. diet and exercise for - Bowel obstruction - dyspepsia - Assess for contraindications and
PO (adults): 3 Result in the reduction of LDL cautions.
tablets twice daily or increased cholesterol in patients - Perform a physical assessment.
6 tablets once daily; clearance of with primary - Weigh the patient.
may be increased to 7 cholesterol, hypercholesterolemia; - Inspect the patient’s skin for
tablets daily. may be used aloe or in color, bruising, and rash.
Therapeutic combination with - Assess neurological status.
effects: HMG-CoA reductase
Decreased inhibitor. Implementation:
cholesterol - Do not administer powdered
agents in dry form.
- If the patient is taking tablets,
ensure that tablets are not cut,
chewed, or crushed.
- Give the drug before meals
- Provide comfort measures.
- Offer support and
encouragement.
- Provide thorough patient
teaching

Evaluation:
- Monitor patient response to the
drug.
- Monitor for adverse effects.
- Monitor for the effectiveness of
comfort measures and
compliance with the regimen.
- Evaluate the effectiveness of the
teaching plan.

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