Name of Drug Mechanism of Action Indication Contraindication Adverse Effect/Side Effect and Nursing

Interaction Responsibilities
- Bactericidal action is - Parenterally for - Hypersensitivity to Central Nervous System: Chills, Before Drug
Vancomycin due to inhibition of potentially life- drug depression, Administration
cell-wall biosynthesis threatening infections dizziness,fatigue,[Link]. - Monitor IV site
and alteration of in patients allergic, - Previous hearing closely.
Minimum dose: bacterial cell nonsensitive or loss Cardiovascular System: Low
125mg membrane resistant to other less blood pressure. - Assess hearing. Drug
permeability and toxic antimicrobial -Allergy to corn or may cause damage to
Maximum dose: ribonucleic acid (RNA) drugs. corn products Gastrointestinal: Abdominal auditory branch of
500mg synthesis. Active pain, constipation. Clostridium eighth cranial nerve
against many gram- - Used orally only in difficile associated diarrhea, with consequent
Patient’s dose: positive organisms. Clostridium difficile nausea and vomiting. deafness, which may
750mg colitis (not effective be permanent.
by oral route for Endocrine System: Itching, Red
Route: treatment of systemic Man Syndrome (due to rapid During Drug
IV Infusion infections. infusion of Vancomycin. Administration
- Avoid rapid infusion
Special Senses: Ototoxicity which may cause
Classification: sudden hypotension.
Urogenital: Nephrotoxicity
Pharmacologic Class: leading to uremia. -Monitor BP and
Tricyclic glycopeptide heart rate
derivative Body as a Whole: continuously through
Hypersensitivity reactions period of drug
Therapeutic Class: (chills,fever, skin rash), administration.
Antibiotic anaphylactoid reaction with
vascular collapse, severe pain, After Drug
thrombophlebitis at injection Administration
site. - Notify prescriber
promptly of ringing in
EENT: Discolored saliva and ears.
sputum.
Hematologic: Transient - Observe IV infusion
leukopenia, eosinophilia, site for evidence of
neutropenia. extravasation,
including necrosis,
Interactions: pain, tenderness and
Drug-drug- Aminoglycosides, thrombophlebitis
amphotericin B, bacitracin,
cephalosporins: increased risk of
nephrotoxicity and ototoxicity.