Bio Test (26.1-26.2D & 26.4)/P.
NSS Biology Test (Ch.26 Basic Genetics-26.1-26.2D &26.4)
Section A: Multiple Choice (6 marks)
1. In a DNA molecule of yeast, 30% of the nitrogenous bases are guanine (G).
What is the ratio of cytosine to thymine (T) in this DNA molecule?
A. 1:1 B. 2:1 C. 3:2 D. 3:7
2. A couple has two children. The son is of blood group B and the daughter is of
blood group A. Which of the following is not a possible combination of
genotypes of this couple?
(Note: The alleles responsible for the production of antigen A, antigen B and
not producing antigen A or B are represented by IA, IB and i respectively.)
A. IA i and IB i B. IA IA and IB i
C. IA IB and IA IB D. IA IB and IB i
3. Two homozygous parents with different phenotypes of the same trait are crossed to
produce some offspring. Which of the following correctly describes the offspring with
trait?
A. The offspring may have two different phenotypes.
B. The offspring are similar to both parents.
C. The offspring only show one phenotype.
D. The offspring are homozygous.
Directions: Questions 4 and 5 refer to the following two crosses of fruit flies. In fruit
flies, males are the heterogametic sex (XY) and the wing shape (normal
wing or cut wing) is controlled by a single gene.
Cross I Cross II
Parents: Normal wing female x Cut wing male Cut wing female x Normal wing male
12 normal wing females 11 normal wing females
F1 11 normal wing males 11 cut wing males
71 normal wing females 32 normal wing females
F2 34 normal wing males 33 cut wing females
35 cut wing males 36 normal wing males
38 cut wing males
4. Which of the following observations from Cross I best supports the conclusion that
normal wing is the dominant phenotype?
A. All the F 1 individuals are normal wing.
B. The ratio of normal wing individuals to cut wing individuals in F2 is 3:1.
C. There are more normal wing individuals than cut wing individuals in the F2.
D. Normal wing males are more or less the same in number as cut wing males in the
F2.
5. From Cross II, we can conclude that
A. the gene for the wing shape is located on the X-chromosome because the cut wing
phenotype was passed from the female parent to the F 1 males.
B. the law of independent assortment was demonstrated because new phenotypes,
including normal wing females and cut wing males, were found in F2.
C. the normal wing male parent is heterozygous because four combinations of
phenotypes were observed in F2 .
D. the gene for the wing shape is located on an autosome because a ratio of [Link]
was shown in F2 .
Bio Test (26.1-26.2D & 26.4)/P.2
6. Which of the following statements about chromosomes and genes is not correct?
A Chromosome is composed of DNA and proteins.
B Gene is a small segment of DNA of a chromosome.
C Chromosomes are present only in cells that are going to divide.
D The position of a gene on a chromosome is called a gene locus.
Section B :Questions (14 marks)
1. The diagram below shows a segment of a polynucleotide chain.
a. Name part Z. (1 marks)
b. State two features of DNA that make it an ideal
genetic material. (2 marks)
2. Red-green colour blindness is an X-linked recessive trait in humans. Peter is red-green
colour blind while his daughter, Mary, is normal.
Deduce Mary’s genotype without using a genetic diagram. (4 marks)
3. The pedigree below shows the inheritance of ability to roll the tongue in a family.
(a) Deduce from the pedigree whether tongue rolling is a dominant or recessive
character. (Do not use genetic diagram) (4 marks)
(b) Draw a genetic diagram of the cross of individuals 1 and 2. (3 marks)
Bio Test (26.1-26.2D & 26.4)/P.3
NSS Biology Test (Ch.26 Basic Genetics-26.1-26.2D &26.4) – Answer sheet
Section A: 6 marks
1. 2. 3. 4. 5. 6.
Section B: 14 marks
1(a)
(b)
3(a)
Bio Test (26.1-26.2D & 26.4)/P.4
3(b)
Bio Test (26.1-26.2D & 26.4)/P.5
NSS Biology Test (Ch.26 Basic Genetics-26.1-26.2D &26.4) – Suggested Answer
Section A: 6 marks
1. 2. 3. 4. 5. 6.
C B C D A C
Section B: 14 marks
1(a) Z: deoxyribose / pentose / 5-carbon sugar (1)
(b) The 3 base of DNA can form genetic code that can codes for 20 amino acids. /
The complementary pairing of specific bases allows accurate replication by semi-
conservative principle. /
To maintain diversity of organism: millions of bases in one DNA molecule can carry a
large amount of information, so all characters can be stored. /
The double helical structure with the bases project inwards, making the DNA a stable
molecule. (any 2) (1,1)
as Mary’s father is red-green colour blind, he must have a X chromosome bearing the
recessive allele for red-green colour blindness (1)
being a female, Mary must have inherited the X chromosome bearing the recessive
allele from her father (1)
on the other hand, Mary is normal, therefore she must have a X chromosome bearing
dominant allele for normal eye sight (1)
3 a Both individuals 1 and 2 are tongue rollers, therefore each of them must possess
at least one allele for tongue rolling. 1m
Individual 6 is a non-tongue roller, that means at least one of his parents must
also possess one allele for non-tongue rolling.
At least one of the parents is heterozygous. 1m
In a heterozygous condition, only the dominant allele will be expressed. 1m
Therefore, tongue rolling is a dominant character. 1m
3m
therefore, Mary is a heterozygote (1)
Bio Test (26.1-26.2D & 26.4)/P.6
