GSSS SEMISTER 1 BIO. FINAL EXAMINATION FOR GRADE 11 2017 E.

NAME________________________________________________ SEC._____ R.N_____

Maximum Marks: 70 Time Allowed 60’s

PART I: Write “True” if the statement is correct and “False” if it is incorrect. ( 5pts.)

1. Enzymes catalyse the chemical reaction by decreasing the kinetic energy of substrates.
2. Inhibition of enzyme is done by blocking its active site called non-competitive inhibition.
3. Lock & key model state that active site of enzyme & substrates are naturally complementary.
4. Enzymes speed up the biochemical reaction and consumed in the process of reaction.
5. Using enzymes in industry allows the reactions to takes place in lower temperature.

PART II : Match the following Reaction catalyzed under column ‘A’ with corresponding enzyme
classes under column ‘B’. (5pts.)

A B

1. Change molecular form of the substrate A. Isomerases

2. Hydrolysis of a substrate B. Ligases

3. Non-hydrolytic removal or addition of a group to a substrate C. Lyases

4. Transfer of a specific group from one substrate to another D. Transferases

5. Joining of two molecules by the formation of new bonds E. Hydrolase

PART III: Fill the blank space with appropriate answer. (3pts)

1. Enzyme acts best at a particular temperature called _____________________.

2. Holoenzyme is made from ________________and _________________.

3. Competitive inhibitors are usually structurally similar to the _______________ .

PART IV: Choose the best answer from the given options & write your choice on the space in
front of the question. (53 pts.)

1. Which one of the following statement explains the specificity of enzymes? Enzymes:

A. Can be used over and over again C. can be destroyed by excessive heat

B. Catalize one reaction only D. do not used at the end of the reaction

2. Which one is different from the rest? A. Competitive inhibitors B. Reversible inhibitors
C. Non-competitive inhibitors D. Irreversible inhibitors

3. A catalyzed reaction involves:

A. High activation energy B. Balanced activation energy C. Low activation energy D. low kinetic
energy

4. Which type of enzyme inhibition its effect is reversed by increasing substrate concentration?

A. Allosteric inhibition B . Non-competitive inhibition C. Competitive inhibition D .End product

inhibition

5. As the temperature increases, the

A. kinetic energy decreases B. probability of substrate & enzyme collision increases

C. charge of amino acids that form the active site is altered. D. probability of substrate & enzyme
collision decreases

6. Only a small amount of enzymes are needed by a single cell because enzymes:

A. Are globular proteins C. Can be used over and over again

B. Are specific for substrate D. Are denatured by high temperature

7. Enzyme are able to lower the activation energy of a chemical reaction by:

A. Increasing the kinetic energy of substrates.

B. Decreasing the kinetic energy of substrates.

C. Creating tension on the covalent bond of substrates.

D. Increasing the temperature of the reaction medium.

8. The region where an enzyme binds with its substrate is called:

A. Substrate B. allosteric site C. active site D. activation energy

9. Digestive enzymes are example of:

A. Oxidoreductase B. Hydrolases C. Isomerase D. Transrerase

10. In key and lock model, the substrate bind on the active site b/c they:

A. have the same shape with the active site C. modify their shape according to the active site

B. have complementary shape with the active site D. A and C

11. An environmental benefit of using enzymes in industrial processes is that it can:

A. reduce use of paper in packaging the product C. increase purity of the product

B. Reduce carbon dioxide emissions D. reduce the costs involved

12. The induced-fit model of enzyme action suggests that, when enzyme and substrate bind, there is a
conformational change in:

A. substrate C. the active site

B. both substrate & active site D. neither substrate nor active site

13. Non-competitive inhibitors alter the shape of the active site by:

A. binding with the allosteric site of the enzyme.

B. competing with the substrate for the active site.

C. altering the structure of the enzyme & inactivating permanently

D. binding with the active site of the enzyme

14. The optimum PH of most mammals are between:

A. 1-3 B. 6-8 C. 4-6 D.8-10

15. Which one of the following substances bind to enzymes & stop or slow down the rate of reaction?

A. Inhibitor B. Activator C .Cofactor D. Substrate

16. Which of the following is not a co-enzyme? A. NAD B. NADP C. FAD D. Mn++

17. In competitive inhibition, inhibitors have a close structural similarity with the
A. Co-enzyme B. Co-factor C. Prosthetic group D. Substrate

18. Uncatalyzed reaction shows ______________ activation energy

A. Lower B. Higher C. Moderate D. Optimum

19. The enzymes which break up starch into sugar are called
A. Hydrolase B. Amylases C. Lipases D. Nucleases
20. Apoenzyme is a A. Protein B. Carbohydrate C. Vitamin D. Amino acid
21. Coenzyme is : A. Always a protein B. Often a metal C. Always an inorganic compound D. Often
a vitamin
22. Enzymes are named after their substrates by adding suffix :
A. -in B. –ase C. -ose D. -sin

23. Homeostasis means

A. Control of internal environment of the body B. Adaptation with the environment
C. Constant environment of the body D. All of the above

24. Which of the following statement is not true about allosteric enzymes?
A. Allosteric enzyme are regulatory enzymes B. Allosteric enzymes have allosteric site
C. Allosteric enzymes have regulatory site D. In allosteric enzymes effector binds to the active site

25. A β pleated sheet organization in a polypeptide chain is an example of _______ structure.

A. primary B. secondary C. tertiary D. quaternary

26. The effect of temperature on the relative rate of action of an enzyme is represented in the
graph.

The optimum temperature for the action of this enzyme is approximately

A. 15°C
B. 22°C
C. 37°C
D. 50°C
27. Which statement best describes the enzyme represented in the graphs given above?
A. This enzyme works best at a temperature of 35°C and a pH of 8.
B. This enzyme works best at a temperature of 50°C and a pH of 12.
C. Temperature and pH have no effect on the action of this enzyme.
D. This enzyme works best at a temperature above 50°C and a pH above 12.

28. A process that occurs in the human body is shown in the diagram. What would happen if a
temperature change caused the shape of the active site to be altered?
A. The dipeptide would digest faster.
B. The dipeptide would digest slower or not at all.
C. The amino acids would combine faster.
D. The amino acids would combine slower or not at all.

29. Which characteristic allows enzymes to function in a specific way?

A. Enzymes are complex compounds composed of starch.
B. Each enzyme has a characteristic shape.
C. Enzymes are long, complex fats.
D. Each enzyme is made up of four subunits.
30. The diagram above illustrates a biochemical process that occurs in organisms. The substance labeled
“catalyst” is also known as
A. a hormone B. an enzyme C. an antibody D. an inorganic compound

31. Base your answer to the question on the information below and on your knowledge of biology.
A student completed a series of experiments and found that a protein-digesting enzyme
(intestinal protease) functions best when the pH is 8.0 and the temperature is 37°C. During an
experiment, the student used some of the procedures listed below.
Procedures
(A) Adding more protease
(B) Adding more protein
(C) Decreasing the pH to 6.0
(D) Increasing the temperature to 45°C
(E) Decreasing the amount of light

32. Which procedure would have the least effect on the rate of protein digestion?
A. procedure A B. procedure E C. procedure C D. procedure D

33. The effect of pH on a certain enzyme is shown in the graph.

33. At what pH would the enzyme be most effective?
A. above 10 B. between 8 and 10 C. between 5 and 7 D. below 5

34. Enzymes have an optimum temperature at which they work best. Temperatures above and below
this optimum will decrease enzyme activity. Which graph best illustrates the effect of
temperature on enzyme activity?

Base your answer to the question on the information below and on your knowledge of
biology.
The graph below shows the effect of substrate concentration on the action of enzyme X. This
enzyme is functioning at its optimal temperature, 36°C, and at its optimal pH, 5.5.
35. When the substrate concentration increases from 0.4% to 0.5%, the rate of the reaction
A. decreases B. increases C. remains the same D. increases, then decreases

36. If our body is to function properly it must regulate…

A. water and salt levels B. pH levels (C) blood sugar levels D. All
37. . _____________ is the process of keeping the body at a constant temperature.
A. osmo regulation B. gluco regulation C. thermo regulation D. euro- regulation
38. ____________ is the means by which a constant blood sugar level is maintained.
A. osmoregulation B. glucoregulation C. thermoregulation D. euro-regulation
39. Which part of the brain monitors the body’s sugar levels, temperature and water content?
A. Hypothalamus B. Hippocampus C. Hypothermus D. Hippopotamus
40. Human enzymes work best at body temperature which is …
A. 0°C B. 24°C C. 30°C D. 37°C
41. The amount of water reabsorbed in the kidney depends on which of the following
hormones? A. ADA B. ATP C. ADH D. insulin
42. The body maintains a constant internal environment by using _________ feedback (which attempts
to reverse the changes that are occurring) A. constructive B. negative C. positive D. destructive

43. Human behavior, like other mammalian behavior, is determined A) strictly by the genes
B) strictly by learning C)by a mixture of genes and learning D)none

44. Which of the following statements is true?

A) Animals can learn to associate any stimuli using classical conditioning.

B) Animals are innately programmed to learn some things more easily than others.

C) Instinctive learning programs explain why most people speak only one language.

D) all of the above

45. Dog salivating at the sound of a can opener.

A) classical conditioning B) fixed-action pattern C) habituation D) operant conditioning

46. A feature that distinguishes most animals from other organisms is that they

A. are multicellular and heterotrophs with no cell wall

B. are multicellular and eukaryotes with a cell wall
C. are asexual and multicellular
D. are sexual and eukaryotes with no cell wall

47. Animal reproduction is ____________ for the most groups.

A. asexual C. heterotrophic
B. sexual D. eukaryotic
48. Which form of reproduction can result from damage to the original animal ?

A. Asexual B. fragmentation C. budding D. parthenogenesis

49. Biotechnology deals with

A. methods to improve crop yield and quality B. classification of plants,

C. diseases and their causes D. the structure of micro-organisms.

[Link] of the following glands produces insulin?

A. Thyroid C. Adrenal

B. Pituitary D. Pancreas

51.A man may drink several liters of water for some days and very much less for the other days.
However, the water balance of his body is always maintained. Which of the following organs of the body
is responsible for such physiological process?

A. Liver B. Lung

C. Heart D. Kidney

52. Which of the following is true about homeostasis?

A. Maintains the level of CO2 in cur body B. Increases the level of CO2 in our body

C. Decreases the level of glucose in our body D. Raise the level of glucose in our body

53. what do you call animals which have body temperature that varies with the external temperature?
A. Poikilotherms B. Hibernators

C. Homoiotherms D. Aestivators

PART 5 : ESSAY TYPE QUESTION (4 pts)

[Link] will happen if the water content of the blood is too high? (2marks)

2. Explain the difference between instinctive behavior and learning behavior (2marks)