MCQ DISCUSSION
PYQ & PYT
ZOOM CLASS
Dr Aishwarya kathuria BY
+916353326112 DR AISHWARYA KATHURIA
NEETPG WITH
DR AISHWARYA KATHURIA
MEDICINE
Q1. Which of the following DMARD use requires regular monitoring of visual
acuity and fundus examination?
A. Methotrexate
B. Hydroxychloroquine
C. Sulfasalazine
D. Leflunomide
Q2. A female presented with burning micturition and symptoms of Urinary Tract
Infection (UTI). Which of the following fluoroquinolones is least likely to be
effective?
A. Ofloxacin
B. Ciprofloxacin
C. Moxifloxacin
D. Levofloxacin
Q3. A patient with heart disease presented with breathlessness. The feature of the
patient is given in the image below. Which of the following is the best drug for the
treatment of edema in this patient?
A. ACE inhibitor
B. Na⁺-K⁺-2Cl⁻ symporter inhibitor in loop of Henle
C. Na⁺-Cl⁻ symporter inhibitor in DCT
D. Aldosterone blocker in DCT
Q4. The graph below depicts the dose-response with multiple administrations of
the drug. Which of the following statements is false regarding the phenomenon
shown in this graph?
A. Drugs are given at short intervals in the same dose
B. Drugs are given at short intervals in gradually increasing doses
C. This incident is seen with drugs such as ephedrine
D. This action is rarely seen in clinical practice
Q5. A patient on anti-cancer therapy developed infection. Blood analysis revealed
a Total Leucocyte Count of 2000/mm³. Which of the following drugs is likely to be
effective in this patient?
A. Romiplostim
B. Oprelvekin
C. Filgrastim
D. Erythropoietin
Q6. A person presents with acute chest pain. Nitroglycerine was given sublingually
and pain relieved within 5 minutes. What is the likely mechanism of this drug?
A. Release of endothelin
B. Release of NO
C. Calcium channel blockade
D. Beta blockade
Q7. Which of the following drugs acts by inhibiting the catechol-O-
methyltransferase enzyme?
A. Amantadine
B. Rotigotine
C. Tolcapone
D. Selegiline
Q8. A patient has pain in the facial nerve distribution while chewing and speaking.
Which of the following drugs should be given for the treatment?
A. Lamotrigine
B. Carbamazepine
C. Phenobarbitone
D. Haloperidol
Q9. Which of the following is a true statement regarding Aliskiren?
A. It is indicated in diabetes mellitus
B. It can be given in pregnancy
C. It increases renin levels
D. It increases aldosterone levels
Q10. A 40-year-old man was treated for a high-grade soft-tissue sarcoma with
radiotherapy. Since he was not responding, he was shifted to chemotherapy. After
initiating chemotherapy, he developed erythematous rashes over the areas where
radiotherapy was administered earlier.
Which of the following drugs causes this condition?
A. Vincristine
B. Doxorubicin
C. Cyclophosphamide
D. 6-mercaptopurine
Q 11. A patient took medication for migraine relief and soon developed numbness
with bluish discolouration of the fingers, as shown in the picture.
Which drug is most likely responsible?
A. Dihydroergotamine
B. Sumatriptan
C. Butorphanol
D. Aspirin
Q12. A female presented with burning micturition and symptoms of Urinary Tract
Infection (UTI).
Which of the following fluoroquinolones is least likely to be effective?
A. Ofloxacin
B. Ciprofloxacin
C. Moxifloxacin
D. Levofloxacin
Q13. Adrenaline acting via beta-2 receptors causes bronchodilation, whereas
histamine acts through H1 receptors to cause bronchoconstriction.
Which type of antagonism is this?
A. Physiological antagonism
B. Chemical antagonism
C. Reversible antagonism
D. Competitive antagonism
Q14. A 4-year-old boy presents with a history of facial edema that has now
progressed to total body swelling involving the face, abdomen, scrotum, and feet.
Urinalysis revealed protein 4+ and a urine protein:creatinine ratio of 3. What is
the initial treatment of choice for this child?
A. Prednisolone
B. Cyclophosphamide
C. Levamisole
D. Cyclosporine
Q15. A 72-year-old male presents with complaints of a weak urinary stream and
frequent urination in small amounts. He is currently on prazosin. He also mentions
that he frequently feels lightheaded and has low blood pressure. Which of the
following alpha-blockers will you prefer to give him?
A. Alfuzosin
B. Terazosin
C. Tamsulosin
D. Doxazosin
Q16. Which monoclonal antibody is used in cancer treatment?
A. Omalizumab
B. Denosumab
C. Rituximab
D. Methotrexate
Q17. A 60-year-old male came to the emergency department after sustaining a
fall. X-ray showed a fractured neck of the femur, and he was operated on for the
same. On post-operative day 2, he experienced a sharp, severe, constant, burning
pain over his right back. On examination, the lesion is as seen below. The area is
tender to light touch with a rash over the area. What is the most appropriate
treatment for this patient?
A. Amitriptyline
B. Topical corticosteroids
C. Valacyclovir
D. Mupirocin
Q18. A 26-year-old woman presents with a unilateral throbbing headache
associated with nausea and vomiting. She has had similar episodes in the past
where the headache usually lasts for 1–2 days. Bright light increases her
discomfort and she prefers sitting in a dark room. Which of the following drugs
can be used to decrease her headache episodes in the future?
A. Propranolol
B. Alprazolam
C. Diazepam
D. Fluoxetine
Q19. Which of the following is a Selective Estrogen Receptor Modulator
(SERM)?
A. Estrogen
B. Metformin
C. Tamoxifen
D. Adriamycin
Q20. A new drug is introduced into the market after which phase of the clinical
trials?
A. Phase I
B. Phase II
C. Phase III
D. Phase IV
Q21. Beta-blockers should be avoided in all except:
A. Asthma
B. Glaucoma
C. Bradycardia
D. Hypothyroidism
