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Overview of Biomedical Engineering Concepts

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0% found this document useful (0 votes)
154 views6 pages

Overview of Biomedical Engineering Concepts

Uploaded by

everexxt16
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Introduction to Biomedical Engineering [BME] Review & Application of Concepts

Name

Directions: As you listen to the presentation, take notes and answer the following questions.

1. Describe three ways that the body resembles a machine. What are some of its limitations?
Possible answers:
● Powered by a pump: heart circulates fluids via heartbeat, heart rate can speed
up/slow down as needed
● Powered by food: food that we eat is digested, broken down into carbohydrates,
fats, and proteins that our body uses for energy production
● Uses electricity to communicate: neurons send pulses of electricity to other
neurons to produce brain activity
● Senses its environment: eyes, nose, ears, fingers/skin; help detect heat, pressure,
vibration, texture, vibrations in air, light intensity, odors, etc.

Limitations:

Possible answers:
● Susceptible to diseases caused by viruses and bacteria
● Can be injured (temporary or permanent)
● Genetic mutations that lead to abnormal development or protein dysregulation
● Body stops working as expected/organ functions begin to break down with age →
body stops repairing itself

2. What is biomedical engineering? How does it address the body as a machine?

● Application of engineering principles to medicine and biology in order to further


someone’s health
● Study of biological systems → improves or recreates them to keep people
healthier for longer
● Also known as bioengineering: applying biology to medicine from engineering
perspective
● Addresses body as machine by helping “repair” the body:
○ Keeps the body running for longer by fixing broken parts
○ Slows the degradation or breakdown of body parts
○ Provides body with new sources of energy
○ Edits out defects (or prevent defects from occurring in the first place)

Created by O. Olshevski, Carnegie Mellon University, 2021


Introduction to Biomedical Engineering [BME] Review & Application of Concepts

3. List the general steps of the BME Design Process. For each step, compare how the
engineering and medical fields approach each step.

1. Identify the problem


● Engineering identifies the needs; medicine identifies the symptoms
● Engineering creates a problem statement: what is the problem? Who has
the problem? Why is it important?
● Medicine uses diagnostic tests and assessments to define the problem:
imaging tests, physical exams, patient histories
2. Define the constraints
● Engineering describes conditions that need to be met by the design
solution; also limits design possibilities by excluding/requiring
specifications (cost, size, weight, material, etc.)
● Medicine describes conditions that must be met with treatment method;
limits treatment options on various physiological and healthcare factors
(cost, time, patient values, medical expertise, etc.)
3. Generate ideas
● Engineering performs research, studies existing solutions (for
improvements and to find aspects that may apply in a new context), and
brainstorms new solutions
● Medicine performs research, considers alternative treatment methods (both
surgical and medication), and examines existing treatment options
(weighing the benefits and drawbacks of each option)
4. Select approach
● Engineering describes the advantages and disadvantages of each solution,
weighs each solution against the design criteria and constraints to ensure
that they’re satisfied, then identifies the best approach
● Medicine describes the risks and benefits of each treatment option, ensures
that the treatment plan is appropriate for the specific patient’s
diagnosis/prognosis, then identifies the best treatment plan
5. Develop design
● Engineering refines the approach by revisiting the specifics of the
problem; once approach is locked in, engineers establish the design
structure and function → may build physical prototypes or create and run
simulations (depending on approach)
● Medicine refines the approach based on patient specifics (medical history,
current symptoms, etc.); once approach is locked in, medical professionals

Created by O. Olshevski, Carnegie Mellon University, 2021


Introduction to Biomedical Engineering [BME] Review & Application of Concepts

establish the treatment component → may design a device or develop a


pharmaceutical (depending on approach)
6. Test solution
● Engineering iterates the design process to improve their current work and
identify any remaining flaws in the design; they evaluate feedback
throughout the process and consider any possible improvements or
upgrades to the design
● Medicine performs clinical trials to identify any common flaws or dangers
associated with the treatment; they also follow up with patients post-
treatment to ensure that the treatment option was successful and that the
individual outcomes were satisfactory and expected

4. What do you think is the most important ethical obligation that a biomedical engineer
has? Why? Name 2-3 situations where this obligation would be relevant. There is no
single correct answer—just provide reasoning to back up your answer.
As noted in the question, answers will vary depending on what the student holds as most
important. The goal of this question is to get students thinking about and contextualizing
ethical obligations in their own lives.

Possible situations:
● Use scientific knowledge for “public good”; prioritize safety, health, and public
welfare when researching or providing a briefing to a group of people (for
example, press briefing on public health concerns)
● Uphold prestige of the BME profession by working truthfully and competently
when researching, teaching, presenting, etc.
● Keep patient information private and confidential in the office, clinic, hospital,
etc.
● Consider consequences of price, availability, and delivery of healthcare when
marketing new product to the medical industry
● Ensure that all guidelines and laws are followed when running animal studies or
clinical models
● Appropriately cite and represent other researchers’ work when including it in
publications
● Present your research accurately, honestly, and clearly so that people will not be
misled
● Train new undergraduates in the lab appropriately; model to new students how to
publish papers and results honestly
● Avoid influence from special interests when training or producing content; keep
science separate from politics, religion, etc.

Created by O. Olshevski, Carnegie Mellon University, 2021


Introduction to Biomedical Engineering [BME] Review & Application of Concepts

Brainstorm Applications
Directions: Name a specific problem or application related to biomedical engineering (for
example, a disease, treatment, medicine, device, surgery, organ, tissue type, complication, lab
technique, medical instrument, etc.) that can be addressed or enhanced by BME.

1. What is the problem or application that can be solved or improved?


Answers will vary, but complete answers will identify who has the problem/need (patient
population), what the problem/need is (problem statement), and why it’s important to
pursue (motivation). Answers will provide appropriate context and background
information and will justify why the problem must be solved or what aspect of a current
solution could be improved.

2. How would information from this presentation help solve or support your problem or
application? What did you hear that is most relevant?
Answers will vary, but complete answers will reference specific slide content. Students
may identify the focus area that is most relevant to their problem/need. They may also
describe their problem/need in terms of a “machine” and illustrate how biomedical
engineering addresses these issues (for example, by “repairing” broken parts). If relevant,
students may reference historical information about the application they hope to improve
(or may use the historical information as an example of an existing solution).

3. After reviewing the presentation, what questions do you still have?

Answers will vary. Questions may ask for teachers to elaborate on the content presented,
or they may point out aspects of biomedical engineering that students are interested in but
that were not addressed in the presentation. This question may be useful in gauging
interest and determining other lesson plans or modules to include to retain engagement.

4. How would the BME Design Process help you find a solution or improvement to the
problem presented above?

a. Identify the problem: What is the problem/need? Who does it impact? Why is it
important?

Answers will vary depending on the problem chosen. Ensure that students are following
the general BME Design Process presented. The goal of the question is to get students
working through the general thought process, and the question is meant to reveal how
many aspects must be considered and addressed in an appropriate design. The grading
focus should be on whether students are engaging with the general process and
justifying their answers, rather than worrying about scientific accuracy. Complete

Created by O. Olshevski, Carnegie Mellon University, 2021


Introduction to Biomedical Engineering [BME] Review & Application of Concepts

answers will demonstrate critical thinking and will show that students are incorporating
the lesson into their personal interests.

b. Define the constraints: What conditions must be met by your solution in order for it to
be successful? What other specifications (cost, size, weight, material, implementation
time, medical expertise, etc.) should be considered for your solution?

Answers will vary.

c. Generate ideas: What solutions already exist, and what aspects of these solutions can
be improved upon? If no solutions exist, why haven’t they been proposed yet?

Answers will vary.

d. Select approach: Why is your solution advantageous? How does it meet the conditions
and specifications stated in part (a)? What risks and benefits does it offer? Why is it
appropriate for the patient population you have in mind? Is it feasible?

Answers will vary.

e. Develop design: How would the solution function? What would the structure be like?
The structure does not need to be complete—just demonstrate that you’ve thought of
how this might be executed or implemented. It may be useful to sketch out the design.

Answers will vary.

f. Test solution: How might you test your solution/improvement? List 2-3 potential
options. How will you know that your product is meeting the specifications? What
feedback or data would you collect? What ethical considerations might you need to
have when testing? Examples such as animal testing, clinical trials, lab experiments,
surveys (either before or after treatment), observations, interviews, user testing

Created by O. Olshevski, Carnegie Mellon University, 2021


Introduction to Biomedical Engineering [BME] Review & Application of Concepts

Answers will vary.

Created by O. Olshevski, Carnegie Mellon University, 2021

Common questions

Powered by AI

Understanding the BME design process is crucial for structuring systematic solutions to medical problems through problem identification, constraint definition, ideation, and testing. For example, addressing complications in diabetic foot ulcers could follow this process by identifying patient needs, defining constraints like affordability and minimal invasiveness, generating ideas such as improved dressing materials, selecting the most promising solution based on effectiveness and patient feedback, developing the design tailored for diabetic physiology, and testing through controlled clinical trials to ensure efficacy and safety .

The BME design process involves: (1) Identifying the problem, where engineering identifies needs while medicine identifies symptoms; (2) Defining constraints, where engineering describes design conditions and limits while medicine describes treatment conditions and limitations; (3) Generating ideas, where engineering researches and brainstorms solutions while medicine considers and examines treatment options; (4) Selecting an approach, where engineering weighs solutions against criteria and medicine evaluates treatment risks and benefits; (5) Developing design, where engineering refines the problem specifics and establishes design structure while medicine refines approaches based on patient specifics; and (6) Testing the solution, where engineering iterates designs for improvement and medicine performs clinical trials for safety and efficacy .

Biomedical engineering treats the body as a machine by applying engineering principles to medicine and biology to repair and enhance body functions. It keeps the body running longer by fixing broken parts, slows degradation of body parts, provides new energy sources, and edits defects to prevent their occurrence. This perception influences health interventions by enabling the creation of devices and treatments that integrate these principles to enhance and restore health functions, thus prolonging healthy living .

Considering ethical obligations is essential in biomedical engineering to ensure the safety, efficacy, and integrity of research and technological developments. Ethical considerations prevent harm to patients, uphold patient rights and confidentiality, and ensure the truthful reporting of results. This maintains public trust, ensures adherence to legal standards, and fosters the responsible creation and deployment of health technologies, which is critical for longitudinal success in healthcare improvements .

The human body functions like a machine in several ways: it is powered by a pump (the heart) that circulates fluids via heartbeat, it uses food which is digested into carbohydrates, fats, and proteins for energy production, and it utilizes electricity for communication through neurons that send pulses to produce brain activity. Additionally, it senses its environment through eyes, nose, ears, and skin detecting heat, pressure, vibration, texture, and more. However, this machine is limited as it is susceptible to diseases caused by viruses and bacteria, can suffer injuries (temporary or permanent), be affected by genetic mutations resulting in abnormal development, and as it ages, organ functions begin to deteriorate, causing the body to stop repairing itself .

Biomedical engineers have ethical responsibilities to use scientific knowledge for public good, prioritize safety and health, and uphold professional integrity. They must keep patient information confidential and present research truthfully. Scenarios where these responsibilities are pertinent include conducting clinical trials where patient well-being and data privacy must be protected, developing medical devices ensuring patient safety, and publishing research where accuracy and honesty are crucial to maintain trust and avoid misinformation .

The biomedical engineering design process facilitates the creation and testing of medical devices by providing a structured framework: (1) Identifying the problem requires understanding clinical needs and patient requirements; (2) Defining constraints involves analyzing material, cost, and medical specifications; (3) Generating ideas requires researching and brainstorming innovative solutions; (4) Selecting an approach involves evaluating potential solutions against constraints; (5) Developing design includes refining designs and building prototypes; and (6) Testing solutions through clinical trials ensures effectiveness and safety. This process ensures that devices meet clinical needs, are safe for patient use, and comply with regulatory standards .

Interdisciplinary collaborations in biomedical engineering involve partnerships among engineers, biologists, medical practitioners, and material scientists. These collaborations contribute to innovation by combining technical expertise and clinical insights, facilitating the development of comprehensive healthcare solutions that address real-world medical problems effectively. For instance, engineers provide technical solutions, while medical practitioners ensure these solutions align with patient care standards, enhancing the design and implementation of biomedical technologies that are practical, effective, and safe for healthcare settings .

Challenges in applying engineering principles to biological systems include variability in biological materials, complexity of human anatomy, and the need for biocompatibility. To address these, solutions such as developing adaptable designs, utilizing biocompatible materials, and implementing computational models for simulation and analysis can be applied. Interdisciplinary collaboration between engineers and medical professionals is also crucial to navigate these challenges effectively and create viable solutions that accommodate patient-specific needs .

Biomedical engineering contributes to the development of diagnostic and therapeutic devices by applying engineering principles to solve biological and medical problems. This includes creating devices like pacemakers, MRI machines, and artificial organs, which improve diagnostic accuracy and treatment effectiveness, leading to non-invasive monitoring and personalized patient care. These advancements significantly enhance the quality of healthcare by ensuring early diagnosis, improving surgical outcomes, and enhancing life quality and longevity for patients .

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